Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.
To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Nasrollahzadeh J et al. | The influence of feeding linoleic, gamma-linolenic and docosahexaenoic acid rich oils on rat brain tumor fatty acids composition and fatty acid binding protein 7 mRNA expression. | 2008 | Lipids Health Dis | pmid:19014610 |
Nandakumar M and Tan MW | Gamma-linolenic and stearidonic acids are required for basal immunity in Caenorhabditis elegans through their effects on p38 MAP kinase activity. | 2008 | PLoS Genet. | pmid:19023415 |
Won J et al. | Stability analysis of zinc oxide-nanoencapsulated conjugated linoleic acid and gamma-linolenic acid. | 2008 | J. Food Sci. | pmid:19019122 |
Cui PH et al. | Monoepoxy octadecadienoates and monoepoxy octadecatrienoates 1: NMR spectral characterization. | 2008 | Chem. Phys. Lipids | pmid:18339314 |
Wu CC et al. | Metabolism of omega-6 polyunsaturated fatty acids in women with dysmenorrhea. | 2008 | Asia Pac J Clin Nutr | pmid:18296341 |
Jeennor S et al. | Evaluation of inoculum performance for enhancing gamma-linolenic acid production from Mucor rouxii. | 2008 | Lett. Appl. Microbiol. | pmid:18298455 |
Puch F et al. | Consumption of functional fermented milk containing borage oil, green tea and vitamin E enhances skin barrier function. | 2008 | Exp. Dermatol. | pmid:18318715 |
Vinggaard AM et al. | Screening of 397 chemicals and development of a quantitative structure--activity relationship model for androgen receptor antagonism. | 2008 | Chem. Res. Toxicol. | pmid:18324785 |
Song C et al. | Long-chain polyunsaturated fatty acids modulate interleukin-1beta-induced changes in behavior, monoaminergic neurotransmitters, and brain inflammation in rats. | 2008 | J. Nutr. | pmid:18424607 |
Funtikova NS and Mysiakina IS | [Effects of conditions for obtaining sporangiospores of the inoculum on the morphology and productivity of the fungus Mucor circinelloides var. lusitanicus 12 M, a producer of gamma-linolenic acid]. | 2008 Jul-Aug | Prikl. Biokhim. Mikrobiol. | pmid:18924414 |
Mysiakina IS and Funtikova NS | [Activity of NAD-dependent isocitrate dehydrogenase, isocitrate lyase, and malate dehydrogenase in Mucor circinelloides var. lusitanicus INMI under different modes of nitrogen supply]. | 2008 Jul-Aug | Mikrobiologiia | pmid:18825970 |
Mysiakina IS and Funtikova NS | [Metabolic characteristics and lipid composition of yeastlike cells and mycelium of Mucor circinelloides var. lusitanicus INMI grown at a high glucose content in the medium]. | 2008 Jul-Aug | Mikrobiologiia | pmid:18825971 |
Pontes-Arruda A et al. | The use of an inflammation-modulating diet in patients with acute lung injury or acute respiratory distress syndrome: a meta-analysis of outcome data. | 2008 Nov-Dec | JPEN J Parenter Enteral Nutr | pmid:18974237 |
Preiser JC | Nutrition therapy for acute respiratory distress syndrome. | 2008 Nov-Dec | JPEN J Parenter Enteral Nutr | pmid:18974251 |
Dickerson RN | Modified EN support for patients with acute respiratory distress syndrome. | 2008 Nov-Dec | JPEN J Parenter Enteral Nutr | pmid:18974252 |
Senapati S et al. | Evening primrose oil is effective in atopic dermatitis: a randomized placebo-controlled trial. | 2008 Sep-Oct | Indian J Dermatol Venereol Leprol | pmid:19052401 |
Ahmed SU et al. | Application of response surface method for studying the role of dissolved oxygen and agitation speed on gamma-linolenic acid production. | 2009 | Appl. Biochem. Biotechnol. | pmid:18480973 |
De Spirt S et al. | Intervention with flaxseed and borage oil supplements modulates skin condition in women. | 2009 | Br. J. Nutr. | pmid:18761778 |
Kong X et al. | Gamma-linolenic acid modulates the response of multidrug-resistant K562 leukemic cells to anticancer drugs. | 2009 | Toxicol In Vitro | pmid:19268700 |
Schnebelen C et al. | Dietary n-3 and n-6 PUFA enhance DHA incorporation in retinal phospholipids without affecting PGE(1) and PGE (2) levels. | 2009 | Lipids | pmid:19242743 |
Miyake JA et al. | Gamma-linolenic acid inhibits both tumour cell cycle progression and angiogenesis in the orthotopic C6 glioma model through changes in VEGF, Flt1, ERK1/2, MMP2, cyclin D1, pRb, p53 and p27 protein expression. | 2009 | Lipids Health Dis | pmid:19292920 |
Ge H et al. | Gamma-linolenic acid induces apoptosis and lipid peroxidation in human chronic myelogenous leukemia K562 cells. | 2009 | Cell Biol. Int. | pmid:19356705 |
Weaver KL et al. | Effect of dietary fatty acids on inflammatory gene expression in healthy humans. | 2009 | J. Biol. Chem. | pmid:19359242 |
Zaniewska A et al. | The activity of lysosomal exoglycosidases in serum of alcohol-dependent men supplemented with borage oil enriched with vitamin E. | 2009 | J Med Food | pmid:19735195 |
Lu H et al. | Identification and characterization of a novel delta6-fatty acid desaturase gene from Rhizopus nigricans. | 2009 | Mol. Biol. Rep. | pmid:19152021 |
Schnebelen C et al. | Nutrition for the eye: different susceptibility of the retina and the lacrimal gland to dietary omega-6 and omega-3 polyunsaturated fatty acid incorporation. | 2009 | Ophthalmic Res. | pmid:19451735 |
Jangbua P et al. | Gamma-linolenic acid production of Mucor rouxii by solid-state fermentation using agricultural by-products. | 2009 | Lett. Appl. Microbiol. | pmid:19453951 |
Smyk B et al. | Steady-state and time-resolved fluorescence studies of stripped Borage oil. | 2009 | Anal. Chim. Acta | pmid:19523559 |
Fakas S et al. | Fatty acid composition in lipid fractions lengthwise the mycelium of Mortierella isabellina and lipid production by solid state fermentation. | 2009 | Bioresour. Technol. | pmid:19574039 |
Viau S et al. | Efficacy of a 2-month dietary supplementation with polyunsaturated fatty acids in dry eye induced by scopolamine in a rat model. | 2009 | Graefes Arch. Clin. Exp. Ophthalmol. | pmid:19415319 |
Wan X et al. | Production of gamma-linolenic acid in Pichia pastoris by Expression of a delta-6 desaturase gene from Cunninghamella echinulata. | 2009 | J. Microbiol. Biotechnol. | pmid:19884765 |
LÃsa M et al. | Comparison of various types of stationary phases in non-aqueous reversed-phase high-performance liquid chromatography-mass spectrometry of glycerolipids in blackcurrant oil and its enzymatic hydrolysis mixture. | 2009 | J Chromatogr A | pmid:19837411 |
Cameron M et al. | Evidence of effectiveness of herbal medicinal products in the treatment of arthritis. Part 2: Rheumatoid arthritis. | 2009 | Phytother Res | pmid:19941324 |
Rodgers A et al. | Evening primrose oil supplementation increases citraturia and decreases other urinary risk factors for calcium oxalate urolithiasis. | 2009 | J. Urol. | pmid:19846138 |
Scheim DE | Cytotoxicity of unsaturated fatty acids in fresh human tumor explants: concentration thresholds and implications for clinical efficacy. | 2009 | Lipids Health Dis | pmid:20003514 |
Lindemann J et al. | Clinical study of the effects on asthma-related QOL and asthma management of a medical food in adult asthma patients. | 2009 | Curr Med Res Opin | pmid:19811112 |
Riaz A et al. | Assessment of anticoagulant effect of evening primrose oil. | 2009 | Pak J Pharm Sci | pmid:19783511 |
Labruzzo BA et al. | Which complementary therapies can help patients with PMS? | 2009 | J Fam Pract | pmid:19874736 |
Ranieri M et al. | The use of alpha-lipoic acid (ALA), gamma linolenic acid (GLA) and rehabilitation in the treatment of back pain: effect on health-related quality of life. | 2009 Jul-Sep | Int J Immunopathol Pharmacol | pmid:19887043 |
Di Geronimo G et al. | Treatment of carpal tunnel syndrome with alpha-lipoic acid. | 2009 Mar-Apr | Eur Rev Med Pharmacol Sci | pmid:19499849 |
Tsai NP et al. | Activation of testicular orphan receptor 4 by fatty acids. | 2009 Nov-Dec | Biochim. Biophys. Acta | pmid:19800043 |
Habermann N et al. | Effects of fatty acids on metabolism and cell growth of human colon cell lines of different transformation state. | 2009 Sep-Oct | Biofactors | pmid:19798733 |
Castellanos P et al. | Changes in fatty acid profiles in testis and spermatozoa of red deer exposed to metal pollution. | 2010 | Reprod. Toxicol. | pmid:20096347 |
Barar J et al. | Barrier functionality and transport machineries of human ECV304 cells. | 2010 | Med. Sci. Monit. | pmid:20037486 |
Itoh S et al. | Antineoplastic effects of gamma linolenic Acid on hepatocellular carcinoma cell lines. | 2010 | J Clin Biochem Nutr | pmid:20664735 |
Huang CB et al. | Antimicrobial activity of n-6, n-7 and n-9 fatty acids and their esters for oral microorganisms. | 2010 | Arch. Oral Biol. | pmid:20541177 |
Ruiz-Rodriguez A et al. | Recent trends in the advanced analysis of bioactive fatty acids. | 2010 | J Pharm Biomed Anal | pmid:19525080 |
Pruthi S et al. | Vitamin E and evening primrose oil for management of cyclical mastalgia: a randomized pilot study. | 2010 | Altern Med Rev | pmid:20359269 |
Chang CS et al. | Gamma-linolenic acid inhibits inflammatory responses by regulating NF-kappaB and AP-1 activation in lipopolysaccharide-induced RAW 264.7 macrophages. | 2010 | Inflammation | pmid:19842026 |
Ribeiro G et al. | The novel ruthenium-gamma-linolenic complex [Ru(2)(aGLA)(4)Cl] inhibits C6 rat glioma cell proliferation and induces changes in mitochondrial membrane potential, increased reactive oxygen species generation and apoptosis in vitro. | 2010 | Cell Biochem. Funct. | pmid:19927275 |