Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.
To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Bates D | Lipids and multiple sclerosis. | 1989 | Biochem. Soc. Trans. | pmid:2546837 |
Santoli D and Zurier RB | Prostaglandin E precursor fatty acids inhibit human IL-2 production by a prostaglandin E-independent mechanism. | 1989 | J. Immunol. | pmid:2545787 |
Watkins BA | Levels of dihomo-gamma-linolenate are depressed in heart phosphatidylcholine and phosphatidylethanolamine in the biotin-deficient chick. | 1989 | Poult. Sci. | pmid:2547210 |
Uccella R et al. | [Action of evening primrose oil on cardiovascular risk factors in insulin-dependent diabetics]. | 1989 | Clin Ter | pmid:2548804 |
Melnik BC and Plewig G | Is the origin of atopy linked to deficient conversion of omega-6-fatty acids to prostaglandin E1? | 1989 | J. Am. Acad. Dermatol. | pmid:2550526 |
Tate G et al. | Suppression of acute and chronic inflammation by dietary gamma linolenic acid. | 1989 | J. Rheumatol. | pmid:2550629 |
Rasmussen JE | Advances in nondietary management of children with atopic dermatitis. | 1989 | Pediatr Dermatol | pmid:2552424 |
Rasmussen JE | Management of atopic dermatitis. | 1989 | Allergy | pmid:2554743 |
Tomlinson DR et al. | Essential fatty acid treatment--effects on nerve conduction, polyol pathway and axonal transport in streptozotocin diabetic rats. | 1989 | Diabetologia | pmid:2477293 |
Horrobin DF | Effects of evening primrose oil in rheumatoid arthritis. | 1989 | Ann. Rheum. Dis. | pmid:2688567 |
Papanikolaou N et al. | Partial protection against acute renal failure by Efamol. | 1989 | Prog. Clin. Biol. Res. | pmid:2798451 |
Ebden P et al. | A study of evening primrose seed oil in atopic asthma. | 1989 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:2717651 |
Huang YS et al. | The prostaglandin outflow from perfused mesenteric vasculature of rats fed different fats. | 1989 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:2717652 |
Siliprandi N | [Significance of evening primrose oil in the problem of the nutritional value of poly-unsaturated fatty acids]. | 1989 Jan-Mar | Minerva Dietol Gastroenterol | pmid:2657494 |
Bégin ME et al. | Differential sensitivity of tumorigenic and genetically related non-tumorigenic cells to cytotoxic polyunsaturated fatty acids. | 1989 Jul-Aug | Anticancer Res. | pmid:2554786 |
Schrek R | An animal model for intractable chronic lymphocytic leukemia. | 1990 | Med. Hypotheses | pmid:1963468 |
Hayashi Y et al. | Anticancer activity of free gamma-linolenic acid on AH-109A rat hepatoma cells and the effect of serum albumin on anticancer activity of gamma-linolenic acid in vitro. | 1990 | J. Pharmacobio-dyn. | pmid:1965510 |
Sharpe GR and Farr PM | Evening primrose oil and eczema. | 1990 | Lancet | pmid:1969047 |
Horrobin DF and Stewart C | Evening primrose oil in atopic eczema. | 1990 | Lancet | pmid:1969596 |
Sharpe GR and Farr PM | Evening primrose oil and eczema. | 1990 | Lancet | pmid:1971352 |
Horrobin DF and Stewart C | Evening primrose oil and atopic eczema. | 1990 | Lancet | pmid:1973228 |
Chapkin RS and Carmichael SL | Effect of dietary blackcurrant seed oil on mouse macrophage subclasses of choline and ethanolamine glycerophospholipids. | 1990 | J. Nutr. | pmid:1974284 |
Dodge JA et al. | Paradoxical effects of essential fatty acid supplementation on lipid profiles and sweat electrolytes in cystic fibrosis. | 1990 | Br. J. Nutr. | pmid:2185826 |
Mansel RE et al. | A randomized trial of dietary intervention with essential fatty acids in patients with categorized cysts. | 1990 | Ann. N. Y. Acad. Sci. | pmid:2192634 |
Nakahara T et al. | Inhibitory effects of mold oil including gamma-linolenate on platelet thrombus formation in mesenteric microvessels of the rat. | 1990 | Thromb. Res. | pmid:2156348 |
Roemen TH et al. | Quantitative assessment of gamma-linolenic acid in human blood and plasma with capillary gas chromatography. | 1990 | J. Chromatogr. | pmid:2166745 |
Cleland LG et al. | The effect of dietary fish oil supplement upon the content of dihomo-gammalinolenic acid in human plasma phospholipids. | 1990 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:2169063 |
van der Merwe CF et al. | The effect of gamma-linolenic acid, an in vitro cytostatic substance contained in evening primrose oil, on primary liver cancer. A double-blind placebo controlled trial. | 1990 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:2169638 |
Hirschberg Y et al. | The response to endotoxin in guinea pigs after intravenous black currant seed oil. | 1990 | Lipids | pmid:2170795 |
Simpson LO | Melanoma and fatty acids. | 1990 | N. Z. Med. J. | pmid:2173823 |
Gamolenic acid in atopic eczema: Epogam. | 1990 | Drug Ther Bull | pmid:2131219 | |
Gateley CA and Mansel RE | Management of cyclical breast pain. | 1990 | Br J Hosp Med | pmid:2364227 |
Watson J et al. | Mechanism of action of polyunsaturated fatty acids in rheumatoid arthritis. | 1990 | Biochem. Soc. Trans. | pmid:2379720 |
Singer P et al. | N-6 and N-3 PUFA in liver lipids, thromboxane formation and blood pressure from SHR during diets supplemented with evening primrose, sunflowerseed or fish oil. | 1990 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:2336450 |
Huang YS et al. | Stress modulates cholesterol-induced changes in plasma and liver fatty acid composition in rats fed n-6 fatty acid-rich oils. | 1990 | Proc. Soc. Exp. Biol. Med. | pmid:2399256 |
Singer P et al. | Blood pressure and serum lipids from SHR after diets supplemented with evening primrose, sunflowerseed or fish oil. | 1990 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:2399267 |
Khoo SK et al. | Evening primrose oil and treatment of premenstrual syndrome. | 1990 | Med. J. Aust. | pmid:2201888 |
Gateley CA et al. | Mastalgia refractory to drug treatment. | 1990 | Br J Surg | pmid:2224458 |
Bordoni A | [Significance and motivation of the clinical use of essential fatty acid derivatives, especially gamma-linolenic acid]. | 1990 | Clin Ter | pmid:2158408 |
Jamal GA and Carmichael H | The effect of gamma-linolenic acid on human diabetic peripheral neuropathy: a double-blind placebo-controlled trial. | 1990 | Diabet. Med. | pmid:2159860 |
Sangeetha P et al. | Free radical generation in human leukocytes by CIS-unsaturated fatty acids is a calmodulin dependent process. | 1990 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:2160083 |
Melnik BC | [A chance for the prevention of atopic diseases]. | 1990 | Monatsschr Kinderheilkd | pmid:2162007 |
Bunce OR and Abou-El-Ela SH | Eicosanoid synthesis and ornithine decarboxylase activity in mammary tumors of rats fed varying levels and types of N-3 and/or N-6 fatty acids. | 1990 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:2177199 |
Huang YS et al. | The effects of dietary protein and cholesterol on tissue cholesterol contents and N-6 fatty acid compositions in rats and mice fed a gamma-linolenate-rich diet. | 1990 | Monogr Atheroscler | pmid:2178226 |
Horrobin DF | Evening primrose oil and premenstrual syndrome. | 1990 | Med. J. Aust. | pmid:2233440 |
Kawashima Y et al. | Peroxisome proliferators enhance linoleic acid metabolism in rat liver. Increased biosynthesis of omega 6 polyunsaturated fatty acids. | 1990 | J. Biol. Chem. | pmid:2160962 |
Abraham RD et al. | Effects of safflower oil and evening primrose oil in men with a low dihomo-gamma-linolenic level. | 1990 | Atherosclerosis | pmid:2112389 |
Ikushima S et al. | Gamma linolenic acid alters the cytotoxic activity of anticancer drugs on cultured human neuroblastoma cells. | 1990 Jul-Aug | Anticancer Res. | pmid:2166461 |
Sircar S et al. | Transformation renders MDR cells more sensitive to polyunsaturated fatty acids. | 1990 Nov-Dec | Anticancer Res. | pmid:2178327 |
Izumi T et al. | Purification of two forms of arachidonate 15-lipoxygenase from human leukocytes. | 1991 | Eur. J. Biochem. | pmid:1662607 |