gamma-Linolenic acid
Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.
Cross Reference
Introduction
To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid
PubChem Associated disorders and diseases
What pathways are associated with gamma-Linolenic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with gamma-Linolenic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with gamma-Linolenic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
What genes are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
What common seen animal models are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with gamma-Linolenic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Tollesson A and Frithz A | Transepidermal water loss and water content in the stratum corneum in infantile seborrhoeic dermatitis. | 1993 | Acta Derm. Venereol. | pmid:8095744 |
| Leventhal LJ et al. | Treatment of rheumatoid arthritis with blackcurrant seed oil. | 1994 | Br. J. Rheumatol. | pmid:8081671 |
| Kirchgessner M et al. | The effects of dietary oils on the fatty acid composition and osmotic fragility of rat erythrocytes. | 1994 | Z Ernahrungswiss | pmid:8079509 |
| Giamarellos-Bourboulis EJ et al. | Do Escherichia coli susceptibilities to various antibiotics decrease in the presence of polyunsaturated fatty acids? A preliminary report. | 1994 | J Chemother | pmid:8071677 |
| Oliwiecki S and Burton JL | Evening primrose oil and marine oil in the treatment of psoriasis. | 1994 | Clin. Exp. Dermatol. | pmid:8050140 |
| Schoemaker JH | Pharmacological treatment of diabetic peripheral neuropathy: challenges and possibilities. | 1994 Mar-Apr | Br J Clin Pract | pmid:8024999 |
| Szczesna M | [Therapeutic assessment of the evening primrose]. | 1993 | Rocz Panstw Zakl Hig | pmid:8016534 |
| du Toit PJ et al. | Pyelonephritis: renal urokinase activity in rats on essential fatty acid diets. | 1994 | Urol. Res. | pmid:7992455 |
| Milner LS et al. | Synergistic effects of fish oil diet and dimethylthiourea in acute adriamycin nephrosis. | 1994 | Am. J. Med. Sci. | pmid:7977444 |
| du Toit PJ et al. | The effect of gamma-linolenic acid and eicosapentaenoic acid on urokinase activity. | 1994 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:7972265 |
| de Kock M et al. | Differential cytotoxic effects of gamma-linolenic acid on MG-63 and HeLa cells. | 1994 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:7972263 |
| Hopewell JW et al. | Amelioration of both early and late radiation-induced damage to pig skin by essential fatty acids. | 1994 | Int. J. Radiat. Oncol. Biol. Phys. | pmid:7961020 |
| Kleijnen J | Evening primrose oil. | 1994 | BMJ | pmid:7950599 |
| Miller MA and Morgan RJ | Eicosanoids, erections and erectile dysfunction. | 1994 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:7938091 |
| Rubin M et al. | Effect of three intravenously administered fat emulsions containing different concentrations of fatty acids on the plasma fatty acid composition of premature infants. | 1994 | J. Pediatr. | pmid:7931881 |
| Biagi PL et al. | The effect of gamma-linolenic acid on clinical status, red cell fatty acid composition and membrane microviscosity in infants with atopic dermatitis. | 1994 | Drugs Exp Clin Res | pmid:7924900 |
| Veale DJ et al. | A double-blind placebo controlled trial of Efamol Marine on skin and joint symptoms of psoriatic arthritis. | 1994 | Br. J. Rheumatol. | pmid:7921757 |
| Stillwell W et al. | Cholesterol condensation of alpha-linolenic and gamma-linolenic acid-containing phosphatidylcholine monolayers and bilayers. | 1994 | Biochim. Biophys. Acta | pmid:7918592 |
| Fiocchi A et al. | The efficacy and safety of gamma-linolenic acid in the treatment of infantile atopic dermatitis. | 1994 Jan-Feb | J. Int. Med. Res. | pmid:7910570 |
| Morris GM et al. | Trophic effects of essential fatty acids on pig skin. | 1995 | Cell Prolif. | pmid:7893841 |
| Karikó K et al. | Stimulatory effect of unsaturated fatty acids on the level of plasminogen activator inhibitor-1 mRNA in cultured human endothelial cells. | 1995 | FEBS Lett. | pmid:7890029 |
| Cameron NE and Cotter MA | Effects of evening primrose oil treatment on sciatic nerve blood flow and endoneurial oxygen tension in streptozotocin-diabetic rats. | 1994 | Acta Diabetol | pmid:7888693 |
| Cartwright-Shamoon JM et al. | A complex biochemical modulation of intestinal ion transport in rats fed on high-fat diets. | 1995 | J. Pediatr. Gastroenterol. Nutr. | pmid:7884616 |
| Purasiri P et al. | Modulation of cytokine production in vivo by dietary essential fatty acids in patients with colorectal cancer. | 1994 | Clin. Sci. | pmid:7874864 |
| Tulloch I et al. | Evening primrose oil reduces urinary calcium excretion in both normal and hypercalciuric rats. | 1994 | Urol. Res. | pmid:7871634 |
| Berth-Jones J et al. | Evening primrose oil and atopic eczema. | 1995 | Lancet | pmid:7861894 |
| Falconer JS et al. | Polyunsaturated fatty acids in the treatment of weight-losing patients with pancreatic cancer. | 1994 | World Rev Nutr Diet | pmid:7856240 |
| McCaul JA and Lamey PJ | Multiple oral mucoceles treated with gamma-linolenic acid: report of a case. | 1994 | Br J Oral Maxillofac Surg | pmid:7849001 |
| Guivernau M et al. | Clinical and experimental study on the long-term effect of dietary gamma-linolenic acid on plasma lipids, platelet aggregation, thromboxane formation, and prostacyclin production. | 1994 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:7846101 |
| Hauben M | Comment: evening primrose oil in the treatment of rheumatoid arthritis--proper application of statistical analysis. | 1994 Jul-Aug | Ann Pharmacother | pmid:7832860 |
| Araya J and Cagalj A | [Exclusion of alpha-linolenic acid from diets for rats during several generations. I. Effect on reproduction and postnatal growth]. | 1993 | Arch Latinoam Nutr | pmid:7826185 |
| Horrobin DF and Morse PF | Evening primrose oil and atopic eczema. | 1995 | Lancet | pmid:7823743 |
| Berth-Jones J and Graham-Brown RA | Evening primrose oil. Does not show promise in atopic dermatitis. | 1994 | BMJ | pmid:7819863 |
| BeLieu RM | Mastodynia. | 1994 | Obstet. Gynecol. Clin. North Am. | pmid:7816407 |
| Darlington LG and Ramsey NW | Review of dietary therapy for rheumatoid arthritis. | 1994 | Compr Ther | pmid:7805365 |
| Tate GA and Zurier RB | Suppression of monosodium urate crystal-induced inflammation by black currant seed oil. | 1994 | Agents Actions | pmid:7741038 |
| Scholey JW and Mills DE | Dietary fatty acids and the glomerular hemodynamic response to cyclosporine in borderline hypertensive rats. | 1995 | Kidney Int. | pmid:7723248 |
| Dines KC et al. | Comparison of the effects of evening primrose oil and triglycerides containing gamma-linolenic acid on nerve conduction and blood flow in diabetic rats. | 1995 | J. Pharmacol. Exp. Ther. | pmid:7714803 |
| Karasu C et al. | Effects of anti-oxidant treatment on sciatic nerve dysfunction in streptozotocin-diabetic rats; comparison with essential fatty acids. | 1995 | Diabetologia | pmid:7713308 |
| Jiang WG et al. | Inhibition of hepatocyte growth factor-induced motility and in vitro invasion of human colon cancer cells by gamma-linolenic acid. | 1995 | Br. J. Cancer | pmid:7710939 |
| Goldfien A | Premenstrual syndrome. | 1994 | Curr Ther Endocrinol Metab | pmid:7704719 |
| Beno DW et al. | Gamma-linolenic acid suppression of hepatic Ito cell mitogenesis: post-PDGF receptor prostaglandin-independent mechanism. | 1993 | Am. J. Physiol. | pmid:7694498 |
| Sherrington EJ et al. | The effect of dietary lipid manipulation on macrophage cell surface molecule expression. | 1995 | Biochem. Soc. Trans. | pmid:7672298 |
| Fan YY et al. | Dietary gamma-linolenic acid modulates macrophage-vascular smooth muscle cell interactions. Evidence for a macrophage-derived soluble factor that downregulates DNA synthesis in smooth muscle cells. | 1995 | Arterioscler. Thromb. Vasc. Biol. | pmid:7670954 |
| Akahane N et al. | Antithrombotic activity of a symmetrical triglyceride with eicosapentaenoic acid and gamma-linolenic acid in guinea pig mesenteric microvasculature. | 1995 | Thromb. Res. | pmid:7660360 |
| Das UN et al. | Local application of gamma-linolenic acid in the treatment of human gliomas. | 1995 | Cancer Lett. | pmid:7634242 |
| Claassen N et al. | Supplemented gamma-linolenic acid and eicosapentaenoic acid influence bone status in young male rats: effects on free urinary collagen crosslinks, total urinary hydroxyproline, and bone calcium content. | 1995 | Bone | pmid:7626328 |
| Jiang WG et al. | Regulation of the expression of E-cadherin on human cancer cells by gamma-linolenic acid (GLA). | 1995 | Cancer Res. | pmid:7585549 |
| Chajès V et al. | Influence of n-3 fatty acids on the growth of human breast cancer cells in vitro: relationship to peroxides and vitamin-E. | 1995 | Breast Cancer Res. Treat. | pmid:7579484 |
| Manninen P et al. | Separation of gamma- and alpha-linolenic acid containing triacylglycerols by capillary supercritical fluid chromatography. | 1995 | Lipids | pmid:7564922 |
| Rossetti RG et al. | Differential regulation of human T lymphocyte protein kinase C activity by unsaturated fatty acids. | 1995 | Clin. Immunol. Immunopathol. | pmid:7554442 |
| Larsson-Backström C et al. | Effects of dietary alpha- and gamma-linolenic acids on liver fatty acids, lipid metabolism, and survival in sepsis. | 1995 | Shock | pmid:7552772 |
| Kietzmann M | [Pharmacotherapeutic use of antipruritic drugs in skin diseases]. | 1995 | Tierarztl Prax | pmid:7545832 |
| Rose DP et al. | Effects of linoleic acid and gamma-linolenic acid on the growth and metastasis of a human breast cancer cell line in nude mice and on its growth and invasive capacity in vitro. | 1995 | Nutr Cancer | pmid:7491296 |
| Hrelia S et al. | Essential fatty acid metabolism in cultured rat cardiomyocytes in response to either N-6 or N-3 fatty acid supplementation. | 1995 | Biochem. Biophys. Res. Commun. | pmid:7488075 |
| Lindskov R and Petersen CS | [Oral gamma-linoleic acid (Epogam) in the treatment of atopic dermatitis]. | 1995 | Ugeskr. Laeg. | pmid:7483071 |
| Kunkel SL et al. | Suppression of chronic inflammation by evening primrose oil. | 1981 | Prog. Lipid Res. | pmid:7342138 |
| Karmali RA et al. | Prostaglandins and essential fatty acids in regulation of autoimmunity and development of antibodies to DNA in NZB x NZW F1 mice. | 1981 | Prog. Lipid Res. | pmid:7342118 |
| Prencipe M et al. | Naudicelle and platelet reactivity in TIA patients. | 1982 | Ital J Neurol Sci | pmid:7166485 |
| Kábrt J et al. | [Serum lipid concentrations in familial hyperlipoproteinaemia type IIa. Treatment with unsaturated fatty acids and vitamin C (author's transl)]. | 1982 | Cas. Lek. Cesk. | pmid:7093988 |
| Kábrt J et al. | [Serum lipid concentration in familial hyperlipoproteinemia type IV. Treatment with vitamin C and unsaturated fatty acids]. | 1983 | Cas. Lek. Cesk. | pmid:6871949 |
| Hanifin JM | Diet, nutrition, and allergy in atopic dermatitis. | 1983 | J. Am. Acad. Dermatol. | pmid:6863636 |
| Phillips JS | Oil of the evening primrose. | 1984 | N. Z. Med. J. | pmid:6589527 |
| Weighill VE and Buglass D | Weight change and psychological state in obese women. | 1984 | Appetite | pmid:6517571 |
| Olsson AG et al. | [Ineffectiveness of Naudicelle in intermittent claudication]. | 1984 | Lakartidningen | pmid:6394928 |
| Manthorpe R et al. | Primary Sjögren's syndrome treated with Efamol/Efavit. A double-blind cross-over investigation. | 1984 | Rheumatol. Int. | pmid:6385206 |
| Haslett C et al. | A double-blind evaluation of evening primrose oil as an antiobesity agent. | 1983 | Int J Obes | pmid:6360923 |
| Horrobin DF | The role of essential fatty acids and prostaglandins in the premenstrual syndrome. | 1983 | J Reprod Med | pmid:6350579 |
| Hoffman P and Förster W | Effects of sunflowerseed oil, linseed oil, evening primrose oil and hydrogenated palm kernel oil on hypertension development in spontaneously hypertensive rats. | 1983 | Prostaglandins Leukot Med | pmid:6348801 |
| Sohal RS et al. | Relationship between lipofuscin granules and polyunsaturated fatty acids in the housefly, Musca domestica. | 1984 | Mech. Ageing Dev. | pmid:6330462 |
| Manku MS et al. | Essential fatty acids in the plasma phospholipids of patients with atopic eczema. | 1984 | Br. J. Dermatol. | pmid:6329254 |
| van der Merwe CF | The reversibility of cancer. | 1984 | S. Afr. Med. J. | pmid:6326340 |
| McCarty MF and Rubin EJ | Rationales for micronutrient supplementation in diabetes. | 1984 | Med. Hypotheses | pmid:6325854 |
| Paccalin J et al. | [Rediscovery of an oleaginous plant: Oenothera biennis. The importance of gamma-linolenic acid in nutrition]. | 1983 | Bull. Acad. Natl. Med. | pmid:6324965 |
| Booyens J and Koenig L | The effect of dietary supplementation with gamma-linolenic acid on the growth of induced tumours in rats. | 1984 | S. Afr. Med. J. | pmid:6324397 |
| Mills DE and Ward R | Attenuation of psychosocial stress-induced hypertension by gamma-linolenic acid (GLA) administration in rats. | 1984 | Proc. Soc. Exp. Biol. Med. | pmid:6324224 |
| Chaintreuil J et al. | Effects of dietary gamma-linolenate supplementation on serum lipids and platelet function in insulin-dependent diabetic patients. | 1984 | Hum Nutr Clin Nutr | pmid:6323358 |
| Hamberg M | Isotope effects in enzymatic and non-enzymatic oxygenation of 6,9,12-octadecatrienoic acid. | 1984 | Biochim. Biophys. Acta | pmid:6322853 |
| Booyens J and Katzeff IE | Cancer: a simple metabolic disease? | 1983 | Med. Hypotheses | pmid:6321917 |
| Van der Merwe CF | The reversibility of cancer. | 1984 | S. Afr. Med. J. | pmid:6320476 |
| Hamberg M | Omega 6-oxygenation of 6, 9, 12-octadecatrienoic acid in human platelets. | 1983 | Biochem. Biophys. Res. Commun. | pmid:6318765 |
| Kemp P and Lander DJ | The hydrogenation of gamma-linolenic acid by pure cultures of two rumen bacteria. | 1983 | Biochem. J. | pmid:6318740 |
| Kirstein D et al. | Effect of dietary fats on the delta 6- and delta 5-desaturation of fatty acids in rat liver microsomes. | 1983 | Br. J. Nutr. | pmid:6315055 |
| Paccalin J et al. | [Changes in the higher derivatives of linoleic acid in cirrhotics treated with gamma-linolenic acid]. | 1983 May-Jun | Therapie | pmid:6310813 |
| Botha JH et al. | Parenteral gamma-linolenic acid administration in nude mice bearing a range of human tumour xenografts. | 1983 | S. Afr. Med. J. | pmid:6304925 |
| Hansen TM et al. | Treatment of rheumatoid arthritis with prostaglandin E1 precursors cis-linoleic acid and gamma-linolenic acid. | 1983 | Scand. J. Rheumatol. | pmid:6304871 |
| Field EJ and Joyce G | Multiple sclerosis: effect of gamma linolenate administration upon membranes and the need for extended clinical trials of unsaturated fatty acids. | 1983 | Eur. Neurol. | pmid:6301844 |
| van der Merwe CF | The reversibility of cancer. | 1983 | S. Afr. Med. J. | pmid:6298954 |
| Renaud S et al. | Comparative beneficial effects on platelet functions and atherosclerosis of dietary linoleic and gamma-linolenic acids in the rabbit. | 1982 | Atherosclerosis | pmid:6297517 |
| Dippenaar N et al. | The reversibility of cancer: evidence that malignancy in human hepatoma cells is gamma-linolenic acid deficiency-dependent. | 1982 | S. Afr. Med. J. | pmid:6291176 |
| Leary WP et al. | Some effects of gamma-linolenic acid on cultured human oesophageal carcinoma cells. | 1982 | S. Afr. Med. J. | pmid:6291175 |
| Varma PK and Persaud TV | Protection against ethanol-induced embryonic damage by administering gamma-linolenic and linoleic acids. | 1982 | Prostaglandins Leukot Med | pmid:6287501 |
| Simmons DA et al. | Significance of tissue myo-inositol concentrations in metabolic regulation in nerve. | 1982 | Science | pmid:6285474 |
| Huang YS et al. | Most biological effects of zinc deficiency corrected by gamma-linolenic acid (18: 3 omega 6) but not by linoleic acid (18: 2 omega 6). | 1982 | Atherosclerosis | pmid:6279122 |
| Bonacossa A et al. | Effect of corticosterone, hydrocortisone and prostaglandin fatty acid precursors on the spontaneous motility of the uterus isolated from ovariectomized rats. | 1982 | Prostaglandins | pmid:6278538 |
| Bodak A et al. | [Comparative study of light and electron microscopic aspects of myocardial lesions induced in the rat by oils with several amounts of gamma-linolenic acid (author's transl)]. | 1982 | Pathol. Biol. | pmid:6278382 |
| Beitz J et al. | Influence of linseed oil diet on the pattern of serum phospholipids in man. | 1981 | Acta Biol. Med. Ger. | pmid:6277115 |
| Darcet P et al. | [Study of the metabolism of fatty acids and total plasma lipids, and platelet aggregation of a population of elderly men using a diet enriched in gamma-linolenic acid]. | 1980 | Ann Nutr Aliment | pmid:6254419 |
| Horrobin DF | A biochemical basis for alcoholism and alcohol-induced damage including the fetal alcohol syndrome and cirrhosis: interference with essential fatty acid and prostaglandin metabolism. | 1980 | Med. Hypotheses | pmid:6253773 |
| Chalmers RJ and Shuster S | Evening primrose seed oil in ichthyosis vulgaris. | 1983 | Lancet | pmid:6130264 |