Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.
To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Laho T et al. | Effects of prefermented cereal-derived substrates (ground barley and rye bran) enriched with fungal γ-linolenic acid on rumen fermentation parameters and lipid metabolism in vitro. | 2011 | J. Appl. Microbiol. | pmid:21672096 |
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Foster RH et al. | Borage oil in the treatment of atopic dermatitis. | 2010 Jul-Aug | Nutrition | pmid:20579590 |
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Castellanos P et al. | Changes in fatty acid profiles in testis and spermatozoa of red deer exposed to metal pollution. | 2010 | Reprod. Toxicol. | pmid:20096347 |
Olveira G et al. | Fatty acid supplements improve respiratory, inflammatory and nutritional parameters in adults with cystic fibrosis. | 2010 | Arch. Bronconeumol. | pmid:20045240 |
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Khongto B et al. | Fermentation process development of recombinant Hansenula polymorpha for gamma-linolenic acid production. | 2010 | J. Microbiol. Biotechnol. | pmid:21124062 |
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Chang CS et al. | Gamma-linolenic acid inhibits inflammatory responses by regulating NF-kappaB and AP-1 activation in lipopolysaccharide-induced RAW 264.7 macrophages. | 2010 | Inflammation | pmid:19842026 |
Ribeiro G et al. | The novel ruthenium-gamma-linolenic complex [Ru(2)(aGLA)(4)Cl] inhibits C6 rat glioma cell proliferation and induces changes in mitochondrial membrane potential, increased reactive oxygen species generation and apoptosis in vitro. | 2010 | Cell Biochem. Funct. | pmid:19927275 |
Kishino S et al. | Microbial production of conjugated gamma-linolenic acid from gamma-linolenic acid by Lactobacillus plantarum AKU 1009a. | 2010 | J. Appl. Microbiol. | pmid:19919619 |
Calder PC | Rationale and use of n-3 fatty acids in artificial nutrition. | 2010 | Proc Nutr Soc | pmid:20441676 |
Chuang LT et al. | Co-expression of heterologous desaturase genes in Yarrowia lipolytica. | 2010 | N Biotechnol | pmid:20188875 |
Ruenwai R et al. | Oxygen-induced expression of Delta(6)-, Delta(9)- and Delta(12)-desaturase genes modulates fatty acid composition in Mucor rouxii. | 2010 | Appl. Microbiol. Biotechnol. | pmid:20187298 |
Fa-lin Z et al. | Efficacy of blackcurrant oil soft capsule, a Chinese herbal drug, in hyperlipidemia treatment. | 2010 | Phytother Res | pmid:20041414 |
Wang H et al. | [Separation of gamma linolenic acid from evening primrose oil with urea inclusion--orthogonal experiment of optimizing technological parameters and observation of urea inclusion compound I]. | 2010 | Zhongguo Zhong Yao Za Zhi | pmid:20707192 |
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Di Geronimo G et al. | Treatment of carpal tunnel syndrome with alpha-lipoic acid. | 2009 Mar-Apr | Eur Rev Med Pharmacol Sci | pmid:19499849 |
Ranieri M et al. | The use of alpha-lipoic acid (ALA), gamma linolenic acid (GLA) and rehabilitation in the treatment of back pain: effect on health-related quality of life. | 2009 Jul-Sep | Int J Immunopathol Pharmacol | pmid:19887043 |
De Spirt S et al. | Intervention with flaxseed and borage oil supplements modulates skin condition in women. | 2009 | Br. J. Nutr. | pmid:18761778 |
Kong X et al. | Gamma-linolenic acid modulates the response of multidrug-resistant K562 leukemic cells to anticancer drugs. | 2009 | Toxicol In Vitro | pmid:19268700 |
Schnebelen C et al. | Dietary n-3 and n-6 PUFA enhance DHA incorporation in retinal phospholipids without affecting PGE(1) and PGE (2) levels. | 2009 | Lipids | pmid:19242743 |
Miyake JA et al. | Gamma-linolenic acid inhibits both tumour cell cycle progression and angiogenesis in the orthotopic C6 glioma model through changes in VEGF, Flt1, ERK1/2, MMP2, cyclin D1, pRb, p53 and p27 protein expression. | 2009 | Lipids Health Dis | pmid:19292920 |
Ge H et al. | Gamma-linolenic acid induces apoptosis and lipid peroxidation in human chronic myelogenous leukemia K562 cells. | 2009 | Cell Biol. Int. | pmid:19356705 |
Weaver KL et al. | Effect of dietary fatty acids on inflammatory gene expression in healthy humans. | 2009 | J. Biol. Chem. | pmid:19359242 |
Zaniewska A et al. | The activity of lysosomal exoglycosidases in serum of alcohol-dependent men supplemented with borage oil enriched with vitamin E. | 2009 | J Med Food | pmid:19735195 |
Lu H et al. | Identification and characterization of a novel delta6-fatty acid desaturase gene from Rhizopus nigricans. | 2009 | Mol. Biol. Rep. | pmid:19152021 |
Viau S et al. | Efficacy of a 2-month dietary supplementation with polyunsaturated fatty acids in dry eye induced by scopolamine in a rat model. | 2009 | Graefes Arch. Clin. Exp. Ophthalmol. | pmid:19415319 |
Wan X et al. | Production of gamma-linolenic acid in Pichia pastoris by Expression of a delta-6 desaturase gene from Cunninghamella echinulata. | 2009 | J. Microbiol. Biotechnol. | pmid:19884765 |
LÃsa M et al. | Comparison of various types of stationary phases in non-aqueous reversed-phase high-performance liquid chromatography-mass spectrometry of glycerolipids in blackcurrant oil and its enzymatic hydrolysis mixture. | 2009 | J Chromatogr A | pmid:19837411 |
Cameron M et al. | Evidence of effectiveness of herbal medicinal products in the treatment of arthritis. Part 2: Rheumatoid arthritis. | 2009 | Phytother Res | pmid:19941324 |
Rodgers A et al. | Evening primrose oil supplementation increases citraturia and decreases other urinary risk factors for calcium oxalate urolithiasis. | 2009 | J. Urol. | pmid:19846138 |
Scheim DE | Cytotoxicity of unsaturated fatty acids in fresh human tumor explants: concentration thresholds and implications for clinical efficacy. | 2009 | Lipids Health Dis | pmid:20003514 |
Lindemann J et al. | Clinical study of the effects on asthma-related QOL and asthma management of a medical food in adult asthma patients. | 2009 | Curr Med Res Opin | pmid:19811112 |
Riaz A et al. | Assessment of anticoagulant effect of evening primrose oil. | 2009 | Pak J Pharm Sci | pmid:19783511 |
Labruzzo BA et al. | Which complementary therapies can help patients with PMS? | 2009 | J Fam Pract | pmid:19874736 |