gamma-Linolenic acid

Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.

Cross Reference

Introduction

To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid

MeSH term MeSH ID Detail
Carpal Tunnel Syndrome D002349 3 associated lipids
Carcinoma, Mucoepidermoid D018277 3 associated lipids
Arthritis, Psoriatic D015535 3 associated lipids
Gastritis, Atrophic D005757 4 associated lipids
Hand Dermatoses D006229 5 associated lipids
Back Pain D001416 5 associated lipids
Intermittent Claudication D007383 6 associated lipids
Xerostomia D014987 6 associated lipids
Raynaud Disease D011928 7 associated lipids
Food Hypersensitivity D005512 7 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with gamma-Linolenic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with gamma-Linolenic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with gamma-Linolenic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with gamma-Linolenic acid

Download all related citations
Per page 10 20 50 100 | Total 1121
Authors Title Published Journal PubMed Link
Bruder ED et al. Metabolic consequences of hypoxia from birth and dexamethasone treatment in the neonatal rat: comprehensive hepatic lipid and fatty acid profiling. 2004 Endocrinology pmid:15271879
Schwartz Z et al. Arachidonic acid directly mediates the rapid effects of 24,25-dihydroxyvitamin D3 via protein kinase C and indirectly through prostaglandin production in resting zone chondrocytes. 1999 Endocrinology pmid:10385391
Simoncíkova P et al. Comparison of the extrapancreatic action of gamma-linolenic acid and n-3 PUFAs in the high fat diet-induced insulin resistance [corrected]. 2002 Endocr Regul pmid:12466014
Zavodnik LB et al. [Effect of gamma-linolenic acid on microsomal oxidation in the rat liver following gamma-irradiation]. 2001 Jul-Aug Eksp Klin Farmakol pmid:11589114
Biagi PL et al. The effect of gamma-linolenic acid on clinical status, red cell fatty acid composition and membrane microviscosity in infants with atopic dermatitis. 1994 Drugs Exp Clin Res pmid:7924900
Biagi PL et al. A long-term study on the use of evening primrose oil (Efamol) in atopic children. 1988 Drugs Exp Clin Res pmid:3048952
Bordoni A et al. Evening primrose oil (Efamol) in the treatment of children with atopic eczema. 1988 Drugs Exp Clin Res pmid:3048953
Cyclical breast pain--what works and what doesn't. 1992 Drug Ther Bull pmid:1425218
Gamolenic acid in atopic eczema: Epogam. 1990 Drug Ther Bull pmid:2131219
Recently introduced products. 1991 Drug Ther Bull pmid:1935601
Wade AE et al. Effect of 7,12-dimethylbenz(a)anthracene administration on hepatic drug metabolizing enzymes in female rats fed corn, primrose, and menhaden oils. 1988 Drug Nutr Interact pmid:3149238
Duffy O et al. Effects of an oil enriched in gamma linolenic acid on locomotor activity and behaviour in the Morris Maze, following in utero ethanol exposure in rats. 1992 Drug Alcohol Depend pmid:1317288
Duffy O et al. Attenuation of the effects of chronic ethanol administration in the brain lipid content of the developing rat by an oil enriched in gamma linolenic acid. 1992 Drug Alcohol Depend pmid:1330473
Huang YS et al. Protective effect of gamma-linolenic acid on aspirin-induced gastric hemorrhage in rats. 1987 Digestion pmid:3030865
Vinik AI et al. Diabetic neuropathies. 2000 Diabetologia pmid:10990072
Cameron NE et al. Effects of alpha-lipoic acid on neurovascular function in diabetic rats: interaction with essential fatty acids. 1998 Diabetologia pmid:9562342
Dines KC et al. Contrasting effects of treatment with omega-3 and omega-6 essential fatty acids on peripheral nerve function and capillarization in streptozotocin-diabetic rats. 1993 Diabetologia pmid:8270127
Cameron NE and Cotter MA Comparison of the effects of ascorbyl gamma-linolenic acid and gamma-linolenic acid in the correction of neurovascular deficits in diabetic rats. 1996 Diabetologia pmid:8877288
Hounsom L et al. Oxidative stress participates in the breakdown of neuronal phenotype in experimental diabetic neuropathy. 2001 Diabetologia pmid:11357471
Stevens EJ et al. Essential fatty acid treatment prevents nerve ischaemia and associated conduction anomalies in rats with experimental diabetes mellitus. 1993 Diabetologia pmid:8314443
Hounsom L et al. A lipoic acid-gamma linolenic acid conjugate is effective against multiple indices of experimental diabetic neuropathy. 1998 Diabetologia pmid:9686927
Tomlinson DR et al. Essential fatty acid treatment--effects on nerve conduction, polyol pathway and axonal transport in streptozotocin diabetic rats. 1989 Diabetologia pmid:2477293
Karasu C et al. Effects of anti-oxidant treatment on sciatic nerve dysfunction in streptozotocin-diabetic rats; comparison with essential fatty acids. 1995 Diabetologia pmid:7713308
Cameron NE et al. Interactions between essential fatty acid, prostanoid, polyol pathway and nitric oxide mechanisms in the neurovascular deficit of diabetic rats. 1996 Diabetologia pmid:8635669
van Doormaal JJ et al. Effects of short-term high dose intake of evening primrose oil on plasma and cellular fatty acid compositions, alpha-tocopherol levels, and erythropoiesis in normal and type 1 (insulin-dependent) diabetic men. 1988 Diabetologia pmid:3065111
Borenshtein D et al. Cataract development in diabetic sand rats treated with alpha-lipoic acid and its gamma-linolenic acid conjugate. 2001 Jan-Feb Diabetes Metab. Res. Rev. pmid:11241890
Keegan A et al. Corpus cavernosum dysfunction in diabetic rats: effects of combined alpha-lipoic acid and gamma-linolenic acid treatment. 2001 Sep-Oct Diabetes Metab. Res. Rev. pmid:11747143
Keen H et al. Treatment of diabetic neuropathy with gamma-linolenic acid. The gamma-Linolenic Acid Multicenter Trial Group. 1993 Diabetes Care pmid:8380765
Shotton HR et al. The effectiveness of treatments of diabetic autonomic neuropathy is not the same in autonomic nerves supplying different organs. 2003 Diabetes pmid:12502507
Horrobin DF Essential fatty acids in the management of impaired nerve function in diabetes. 1997 Diabetes pmid:9285506
Cameron NE et al. Essential fatty acid diet supplementation. Effects on peripheral nerve and skeletal muscle function and capillarization in streptozocin-induced diabetic rats. 1991 Diabetes pmid:2022301
Jamal GA The use of gamma linolenic acid in the prevention and treatment of diabetic neuropathy. 1994 Diabet. Med. pmid:8200197
Jamal GA and Carmichael H The effect of gamma-linolenic acid on human diabetic peripheral neuropathy: a double-blind placebo-controlled trial. 1990 Diabet. Med. pmid:2159860
Whitaker DK et al. Evening primrose oil (Epogam) in the treatment of chronic hand dermatitis: disappointing therapeutic results. 1996 Dermatology (Basel) pmid:8884146
Worm M and Henz BM Novel unconventional therapeutic approaches to atopic eczema. 2000 Dermatology (Basel) pmid:11096188
Mayo TT et al. Comparative study on bruise reduction treatments after bruise induction using the pulsed dye laser. 2013 Dermatol Surg pmid:23899131
Mettang T Uremic Itch Management. 2016 Curr. Probl. Dermatol. pmid:27578082
Goldfien A Premenstrual syndrome. 1994 Curr Ther Endocrinol Metab pmid:7704719
Das UN Tumoricidal and anti-angiogenic actions of gamma-linolenic acid and its derivatives. 2006 Curr Pharm Biotechnol pmid:17168663
Morse NL and Clough PM A meta-analysis of randomized, placebo-controlled clinical trials of Efamol evening primrose oil in atopic eczema. Where do we go from here in light of more recent discoveries? 2006 Curr Pharm Biotechnol pmid:17168667
Kapoor R and Huang YS Gamma linolenic acid: an antiinflammatory omega-6 fatty acid. 2006 Curr Pharm Biotechnol pmid:17168669
Lindemann J et al. Clinical study of the effects on asthma-related QOL and asthma management of a medical food in adult asthma patients. 2009 Curr Med Res Opin pmid:19811112
Surette ME et al. The impact of a medical food containing gammalinolenic and eicosapentaenoic acids on asthma management and the quality of life of adult asthma patients. 2008 Curr Med Res Opin pmid:18194593
Mancuso P et al. Effects of eicosapentaenoic and gamma-linolenic acid on lung permeability and alveolar macrophage eicosanoid synthesis in endotoxic rats. 1997 Crit. Care Med. pmid:9118672
Gasperino J and Kvetan V Acute lung injury and nutritional support. 2006 Crit. Care Med. pmid:16550085
Karlstad MD et al. Effect of intravenous lipid emulsions enriched with gamma-linolenic acid on plasma n-6 fatty acids and prostaglandin biosynthesis after burn and endotoxin injury in rats. 1993 Crit. Care Med. pmid:8222692
Gadek JE et al. Effect of enteral feeding with eicosapentaenoic acid, gamma-linolenic acid, and antioxidants in patients with acute respiratory distress syndrome. Enteral Nutrition in ARDS Study Group. 1999 Crit. Care Med. pmid:10470743
Wiedemann HP Fish oil is not the fix for acute lung injury. 2011 Crit. Care Med. pmid:21685749
Curtis L High-quality enteral nutrition essential for reducing morbidity and mortality in acute care patients. 2007 Crit. Care Med. pmid:17421112
Pacht ER et al. Enteral nutrition with eicosapentaenoic acid, gamma-linolenic acid, and antioxidants reduces alveolar inflammatory mediators and protein influx in patients with acute respiratory distress syndrome. 2003 Crit. Care Med. pmid:12576957