gamma-Linolenic acid

Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.

Cross Reference

Introduction

To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid

MeSH term MeSH ID Detail
Cell Transformation, Neoplastic D002471 126 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Dermatitis D003872 30 associated lipids
Dermatitis, Atopic D003876 19 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Dyskinesia, Drug-Induced D004409 15 associated lipids
Per page 10 20 50 100 | Total 85

PubChem Associated disorders and diseases

What pathways are associated with gamma-Linolenic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with gamma-Linolenic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with gamma-Linolenic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with gamma-Linolenic acid

Download all related citations
Per page 10 20 50 100 | Total 1121
Authors Title Published Journal PubMed Link
Hamilton LA and Trobaugh KA Acute respiratory distress syndrome: use of specialized nutrients in pediatric patients and infants. 2011 Nutr Clin Pract pmid:21266694
Ghoreishi SM et al. Separation of γ-linolenic and other polyunsaturated fatty acids from Boraginaceae via supercritical CO2. 2011 J Sep Sci pmid:21246730
Li J et al. Feeding stimulant in Cinnamomum camphora for the common bluebottle, Graphium sarpedon nipponum (Lepidoptera: Papilionidae). 2010 Sep-Oct Z. Naturforsch., C, J. Biosci. pmid:21138058
Khongto B et al. Fermentation process development of recombinant Hansenula polymorpha for gamma-linolenic acid production. 2010 J. Microbiol. Biotechnol. pmid:21124062
Abraham RD et al. Effects of safflower oil and evening primrose oil in men with a low dihomo-gamma-linolenic level. 1990 Atherosclerosis pmid:2112389
Wang H et al. [Separation of gamma linolenic acid from evening primrose oil with urea inclusion--orthogonal experiment of optimizing technological parameters and observation of urea inclusion compound I]. 2010 Zhongguo Zhong Yao Za Zhi pmid:20707192
Itoh S et al. Antineoplastic effects of gamma linolenic Acid on hepatocellular carcinoma cell lines. 2010 J Clin Biochem Nutr pmid:20664735
Ferrie S Re: The use of an inflammation-modulating diet in patients with acute lung injury or acute respiratory distress syndrome: a meta-analysis of outcome data. 2010 Jul-Aug JPEN J Parenter Enteral Nutr pmid:20631393
Das UN Polyunsaturated fatty acids and atopic dermatitis. 2010 Jul-Aug Nutrition pmid:20579591
Foster RH et al. Borage oil in the treatment of atopic dermatitis. 2010 Jul-Aug Nutrition pmid:20579590
Huang CB et al. Antimicrobial activity of n-6, n-7 and n-9 fatty acids and their esters for oral microorganisms. 2010 Arch. Oral Biol. pmid:20541177
Calder PC Rationale and use of n-3 fatty acids in artificial nutrition. 2010 Proc Nutr Soc pmid:20441676
Pruthi S et al. Vitamin E and evening primrose oil for management of cyclical mastalgia: a randomized pilot study. 2010 Altern Med Rev pmid:20359269
Cameron NE et al. Essential fatty acid diet supplementation. Effects on peripheral nerve and skeletal muscle function and capillarization in streptozocin-induced diabetic rats. 1991 Diabetes pmid:2022301
Say B A panacea for all ills? 1991 Apr 10-16 Nurs Times pmid:2020583
Chuang LT et al. Co-expression of heterologous desaturase genes in Yarrowia lipolytica. 2010 N Biotechnol pmid:20188875
Ruenwai R et al. Oxygen-induced expression of Delta(6)-, Delta(9)- and Delta(12)-desaturase genes modulates fatty acid composition in Mucor rouxii. 2010 Appl. Microbiol. Biotechnol. pmid:20187298
Castellanos P et al. Changes in fatty acid profiles in testis and spermatozoa of red deer exposed to metal pollution. 2010 Reprod. Toxicol. pmid:20096347
Holborow P Melanoma and fatty acids. 1991 N. Z. Med. J. pmid:2008253
Holborow P Melanoma and polyunsaturated fat. 1991 N. Z. Med. J. pmid:2006066
Olveira G et al. Fatty acid supplements improve respiratory, inflammatory and nutritional parameters in adults with cystic fibrosis. 2010 Arch. Bronconeumol. pmid:20045240
Fa-lin Z et al. Efficacy of blackcurrant oil soft capsule, a Chinese herbal drug, in hyperlipidemia treatment. 2010 Phytother Res pmid:20041414
Barar J et al. Barrier functionality and transport machineries of human ECV304 cells. 2010 Med. Sci. Monit. pmid:20037486
Scheim DE Cytotoxicity of unsaturated fatty acids in fresh human tumor explants: concentration thresholds and implications for clinical efficacy. 2009 Lipids Health Dis pmid:20003514
Simpson LO Melanoma and fatty acids. 1991 N. Z. Med. J. pmid:1996191
Cameron M et al. Evidence of effectiveness of herbal medicinal products in the treatment of arthritis. Part 2: Rheumatoid arthritis. 2009 Phytother Res pmid:19941324
Ribeiro G et al. The novel ruthenium-gamma-linolenic complex [Ru(2)(aGLA)(4)Cl] inhibits C6 rat glioma cell proliferation and induces changes in mitochondrial membrane potential, increased reactive oxygen species generation and apoptosis in vitro. 2010 Cell Biochem. Funct. pmid:19927275
Kishino S et al. Microbial production of conjugated gamma-linolenic acid from gamma-linolenic acid by Lactobacillus plantarum AKU 1009a. 2010 J. Appl. Microbiol. pmid:19919619
Ranieri M et al. The use of alpha-lipoic acid (ALA), gamma linolenic acid (GLA) and rehabilitation in the treatment of back pain: effect on health-related quality of life. 2009 Jul-Sep Int J Immunopathol Pharmacol pmid:19887043
Wan X et al. Production of gamma-linolenic acid in Pichia pastoris by Expression of a delta-6 desaturase gene from Cunninghamella echinulata. 2009 J. Microbiol. Biotechnol. pmid:19884765
Labruzzo BA et al. Which complementary therapies can help patients with PMS? 2009 J Fam Pract pmid:19874736
Rodgers A et al. Evening primrose oil supplementation increases citraturia and decreases other urinary risk factors for calcium oxalate urolithiasis. 2009 J. Urol. pmid:19846138
Chang CS et al. Gamma-linolenic acid inhibits inflammatory responses by regulating NF-kappaB and AP-1 activation in lipopolysaccharide-induced RAW 264.7 macrophages. 2010 Inflammation pmid:19842026
Lísa M et al. Comparison of various types of stationary phases in non-aqueous reversed-phase high-performance liquid chromatography-mass spectrometry of glycerolipids in blackcurrant oil and its enzymatic hydrolysis mixture. 2009 J Chromatogr A pmid:19837411
Lindemann J et al. Clinical study of the effects on asthma-related QOL and asthma management of a medical food in adult asthma patients. 2009 Curr Med Res Opin pmid:19811112
Tsai NP et al. Activation of testicular orphan receptor 4 by fatty acids. 2009 Nov-Dec Biochim. Biophys. Acta pmid:19800043
Habermann N et al. Effects of fatty acids on metabolism and cell growth of human colon cell lines of different transformation state. 2009 Sep-Oct Biofactors pmid:19798733
Riaz A et al. Assessment of anticoagulant effect of evening primrose oil. 2009 Pak J Pharm Sci pmid:19783511
Chapkin RS and Carmichael SL Effect of dietary blackcurrant seed oil on mouse macrophage subclasses of choline and ethanolamine glycerophospholipids. 1990 J. Nutr. pmid:1974284
Zaniewska A et al. The activity of lysosomal exoglycosidases in serum of alcohol-dependent men supplemented with borage oil enriched with vitamin E. 2009 J Med Food pmid:19735195
Horrobin DF and Stewart C Evening primrose oil and atopic eczema. 1990 Lancet pmid:1973228
Platzbecker U et al. Reduction of 5-azacitidine induced skin reactions in MDS patients with evening primrose oil. 2010 Ann. Hematol. pmid:19714330
Sharpe GR and Farr PM Evening primrose oil and eczema. 1990 Lancet pmid:1971352
Horrobin DF and Stewart C Evening primrose oil in atopic eczema. 1990 Lancet pmid:1969596
Sharpe GR and Farr PM Evening primrose oil and eczema. 1990 Lancet pmid:1969047
Hayashi Y et al. Anticancer activity of free gamma-linolenic acid on AH-109A rat hepatoma cells and the effect of serum albumin on anticancer activity of gamma-linolenic acid in vitro. 1990 J. Pharmacobio-dyn. pmid:1965510
Schrek R An animal model for intractable chronic lymphocytic leukemia. 1990 Med. Hypotheses pmid:1963468
Fakas S et al. Fatty acid composition in lipid fractions lengthwise the mycelium of Mortierella isabellina and lipid production by solid state fermentation. 2009 Bioresour. Technol. pmid:19574039
Ruiz-Rodriguez A et al. Recent trends in the advanced analysis of bioactive fatty acids. 2010 J Pharm Biomed Anal pmid:19525080
Smyk B et al. Steady-state and time-resolved fluorescence studies of stripped Borage oil. 2009 Anal. Chim. Acta pmid:19523559
Di Geronimo G et al. Treatment of carpal tunnel syndrome with alpha-lipoic acid. 2009 Mar-Apr Eur Rev Med Pharmacol Sci pmid:19499849
Jangbua P et al. Gamma-linolenic acid production of Mucor rouxii by solid-state fermentation using agricultural by-products. 2009 Lett. Appl. Microbiol. pmid:19453951
Schnebelen C et al. Nutrition for the eye: different susceptibility of the retina and the lacrimal gland to dietary omega-6 and omega-3 polyunsaturated fatty acid incorporation. 2009 Ophthalmic Res. pmid:19451735
Ring J and Kleinheinz A [Evening primrose oil in neurodermatitis?]. 1991 Med Monatsschr Pharm pmid:1943974
Schäfer L and Kragballe K Supplementation with evening primrose oil in atopic dermatitis: effect on fatty acids in neutrophils and epidermis. 1991 Lipids pmid:1943500
Viau S et al. Efficacy of a 2-month dietary supplementation with polyunsaturated fatty acids in dry eye induced by scopolamine in a rat model. 2009 Graefes Arch. Clin. Exp. Ophthalmol. pmid:19415319
Weaver KL et al. Effect of dietary fatty acids on inflammatory gene expression in healthy humans. 2009 J. Biol. Chem. pmid:19359242
Ge H et al. Gamma-linolenic acid induces apoptosis and lipid peroxidation in human chronic myelogenous leukemia K562 cells. 2009 Cell Biol. Int. pmid:19356705
Recently introduced products. 1991 Drug Ther Bull pmid:1935601
Miyake JA et al. Gamma-linolenic acid inhibits both tumour cell cycle progression and angiogenesis in the orthotopic C6 glioma model through changes in VEGF, Flt1, ERK1/2, MMP2, cyclin D1, pRb, p53 and p27 protein expression. 2009 Lipids Health Dis pmid:19292920
Kong X et al. Gamma-linolenic acid modulates the response of multidrug-resistant K562 leukemic cells to anticancer drugs. 2009 Toxicol In Vitro pmid:19268700
Shi LM et al. [Effects of gamma linolenic acid on atherosclerosis induced by cholesterol-rich diet in rats]. 2008 Zhongguo Zhong Yao Za Zhi pmid:19260318
Schnebelen C et al. Dietary n-3 and n-6 PUFA enhance DHA incorporation in retinal phospholipids without affecting PGE(1) and PGE (2) levels. 2009 Lipids pmid:19242743
Wright S Atopic eczema. 1991 J R Coll Physicians Lond pmid:1920221
Lu H et al. Identification and characterization of a novel delta6-fatty acid desaturase gene from Rhizopus nigricans. 2009 Mol. Biol. Rep. pmid:19152021
Brzeski M et al. Evening primrose oil in patients with rheumatoid arthritis and side-effects of non-steroidal anti-inflammatory drugs. 1991 Br. J. Rheumatol. pmid:1913008
Senapati S et al. Evening primrose oil is effective in atopic dermatitis: a randomized placebo-controlled trial. 2008 Sep-Oct Indian J Dermatol Venereol Leprol pmid:19052401
Nandakumar M and Tan MW Gamma-linolenic and stearidonic acids are required for basal immunity in Caenorhabditis elegans through their effects on p38 MAP kinase activity. 2008 PLoS Genet. pmid:19023415
Won J et al. Stability analysis of zinc oxide-nanoencapsulated conjugated linoleic acid and gamma-linolenic acid. 2008 J. Food Sci. pmid:19019122
Nasrollahzadeh J et al. The influence of feeding linoleic, gamma-linolenic and docosahexaenoic acid rich oils on rat brain tumor fatty acids composition and fatty acid binding protein 7 mRNA expression. 2008 Lipids Health Dis pmid:19014610
Dickerson RN Modified EN support for patients with acute respiratory distress syndrome. 2008 Nov-Dec JPEN J Parenter Enteral Nutr pmid:18974252
Preiser JC Nutrition therapy for acute respiratory distress syndrome. 2008 Nov-Dec JPEN J Parenter Enteral Nutr pmid:18974251
Pontes-Arruda A et al. The use of an inflammation-modulating diet in patients with acute lung injury or acute respiratory distress syndrome: a meta-analysis of outcome data. 2008 Nov-Dec JPEN J Parenter Enteral Nutr pmid:18974237
Funtikova NS and Mysiakina IS [Effects of conditions for obtaining sporangiospores of the inoculum on the morphology and productivity of the fungus Mucor circinelloides var. lusitanicus 12 M, a producer of gamma-linolenic acid]. 2008 Jul-Aug Prikl. Biokhim. Mikrobiol. pmid:18924414
Mysiakina IS and Funtikova NS [Metabolic characteristics and lipid composition of yeastlike cells and mycelium of Mucor circinelloides var. lusitanicus INMI grown at a high glucose content in the medium]. 2008 Jul-Aug Mikrobiologiia pmid:18825971
Mysiakina IS and Funtikova NS [Activity of NAD-dependent isocitrate dehydrogenase, isocitrate lyase, and malate dehydrogenase in Mucor circinelloides var. lusitanicus INMI under different modes of nitrogen supply]. 2008 Jul-Aug Mikrobiologiia pmid:18825970
De Spirt S et al. Intervention with flaxseed and borage oil supplements modulates skin condition in women. 2009 Br. J. Nutr. pmid:18761778
Arisaka M et al. Fatty acid and prostaglandin metabolism in children with diabetes mellitus. II. The effect of evening primrose oil supplementation on serum fatty acid and plasma prostaglandin levels. 1991 Prostaglandins Leukot. Essent. Fatty Acids pmid:1871184
Horrobin DF et al. The effects of evening primrose oil, safflower oil and paraffin on plasma fatty acid levels in humans: choice of an appropriate placebo for clinical studies on primrose oil. 1991 Prostaglandins Leukot. Essent. Fatty Acids pmid:1871175
Thumfart J et al. Magnesium stimulates renal phosphate reabsorption. 2008 Am. J. Physiol. Renal Physiol. pmid:18701629
Fakas S et al. Gamma-linolenic acid production by Cunninghamella echinulata growing on complex organic nitrogen sources. 2008 Bioresour. Technol. pmid:18609766
Guo JP and Xue H [Prepared evening primrose oil microspheres by spray drying]. 2008 Zhongguo Zhong Yao Za Zhi pmid:18589773
Leskinen H et al. Regioisomeric structure determination of alpha- and gamma-linolenoyldilinoleoylglycerol in blackcurrant seed oil by silver ion high-performance liquid chromatography and mass spectrometry. 2008 Anal. Chem. pmid:18578547
Clément M et al. Purification and identification of bovine cheese whey fatty acids exhibiting in vitro antifungal activity. 2008 J. Dairy Sci. pmid:18565910
Adam O [Ankylosing Spondylitis and convenient nutrition]. 2008 Wien Med Wochenschr pmid:18560957
Bloom P Atopic dermatitis: the quest for the silver bullet. 2008 Vet. J. pmid:18554562
Das UN Tumoricidal action of cis-unsaturated fatty acids and their relationship to free radicals and lipid peroxidation. 1991 Cancer Lett. pmid:1850658
Yu Q et al. LC/ESR/MS study of spin trapped carbon-centred radicals formed from in vitro lipoxygenase-catalysed peroxidation of gamma-linolenic acid. 2008 Free Radic. Res. pmid:18484409
Ahmed SU et al. Application of response surface method for studying the role of dissolved oxygen and agitation speed on gamma-linolenic acid production. 2009 Appl. Biochem. Biotechnol. pmid:18480973
Song C et al. Long-chain polyunsaturated fatty acids modulate interleukin-1beta-induced changes in behavior, monoaminergic neurotransmitters, and brain inflammation in rats. 2008 J. Nutr. pmid:18424607
Prociuk MA et al. Cholesterol-induced stimulation of platelet aggregation is prevented by a hempseed-enriched diet. 2008 Can. J. Physiol. Pharmacol. pmid:18418423
Choi GG et al. Enhanced biomass and gamma-linolenic acid production of mutant strain Arthrospira platensis. 2008 J. Microbiol. Biotechnol. pmid:18388474
Gateley CA and Mansel RE Management of the painful and nodular breast. 1991 Br. Med. Bull. pmid:1834299
Cui PH et al. Monoepoxy octadecadienoates and monoepoxy octadecatrienoates 1: NMR spectral characterization. 2008 Chem. Phys. Lipids pmid:18339314
Vinggaard AM et al. Screening of 397 chemicals and development of a quantitative structure--activity relationship model for androgen receptor antagonism. 2008 Chem. Res. Toxicol. pmid:18324785
Puch F et al. Consumption of functional fermented milk containing borage oil, green tea and vitamin E enhances skin barrier function. 2008 Exp. Dermatol. pmid:18318715
Jeennor S et al. Evaluation of inoculum performance for enhancing gamma-linolenic acid production from Mucor rouxii. 2008 Lett. Appl. Microbiol. pmid:18298455
Wu CC et al. Metabolism of omega-6 polyunsaturated fatty acids in women with dysmenorrhea. 2008 Asia Pac J Clin Nutr pmid:18296341
Chilton FH et al. Mechanisms by which botanical lipids affect inflammatory disorders. 2008 Am. J. Clin. Nutr. pmid:18258646
Yen CH et al. Linoleic acid metabolite levels and transepidermal water loss in children with atopic dermatitis. 2008 Ann. Allergy Asthma Immunol. pmid:18254485