gamma-Linolenic acid

Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.

Cross Reference

Introduction

To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid

MeSH term MeSH ID Detail
Neovascularization, Pathologic D009389 39 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Leukemia P388 D007941 43 associated lipids
Psoriasis D011565 47 associated lipids
Thrombosis D013927 49 associated lipids
Osteosarcoma D012516 50 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Pain D010146 64 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Neuroblastoma D009447 66 associated lipids
Melanoma D008545 69 associated lipids
Hyperlipidemias D006949 73 associated lipids
Stomach Ulcer D013276 75 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Atherosclerosis D050197 85 associated lipids
Arteriosclerosis D001161 86 associated lipids
Seizures D012640 87 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Insulin Resistance D007333 99 associated lipids
Weight Gain D015430 101 associated lipids
Glioma D005910 112 associated lipids
Hypertension D006973 115 associated lipids
Inflammation D007249 119 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Adenocarcinoma D000230 166 associated lipids
Lung Neoplasms D008175 171 associated lipids
Body Weight D001835 333 associated lipids
Per page 10 20 50 100 | Total 85

PubChem Associated disorders and diseases

What pathways are associated with gamma-Linolenic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with gamma-Linolenic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with gamma-Linolenic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with gamma-Linolenic acid

Download all related citations
Per page 10 20 50 100 | Total 1121
Authors Title Published Journal PubMed Link
Olveira G et al. Fatty acid supplements improve respiratory, inflammatory and nutritional parameters in adults with cystic fibrosis. 2010 Arch. Bronconeumol. pmid:20045240
Holborow P Melanoma and polyunsaturated fat. 1991 N. Z. Med. J. pmid:2006066
Holborow P Melanoma and fatty acids. 1991 N. Z. Med. J. pmid:2008253
Castellanos P et al. Changes in fatty acid profiles in testis and spermatozoa of red deer exposed to metal pollution. 2010 Reprod. Toxicol. pmid:20096347
Ruenwai R et al. Oxygen-induced expression of Delta(6)-, Delta(9)- and Delta(12)-desaturase genes modulates fatty acid composition in Mucor rouxii. 2010 Appl. Microbiol. Biotechnol. pmid:20187298
Chuang LT et al. Co-expression of heterologous desaturase genes in Yarrowia lipolytica. 2010 N Biotechnol pmid:20188875
Say B A panacea for all ills? 1991 Apr 10-16 Nurs Times pmid:2020583
Cameron NE et al. Essential fatty acid diet supplementation. Effects on peripheral nerve and skeletal muscle function and capillarization in streptozocin-induced diabetic rats. 1991 Diabetes pmid:2022301
Pruthi S et al. Vitamin E and evening primrose oil for management of cyclical mastalgia: a randomized pilot study. 2010 Altern Med Rev pmid:20359269
Calder PC Rationale and use of n-3 fatty acids in artificial nutrition. 2010 Proc Nutr Soc pmid:20441676
Huang CB et al. Antimicrobial activity of n-6, n-7 and n-9 fatty acids and their esters for oral microorganisms. 2010 Arch. Oral Biol. pmid:20541177
Foster RH et al. Borage oil in the treatment of atopic dermatitis. 2010 Jul-Aug Nutrition pmid:20579590
Das UN Polyunsaturated fatty acids and atopic dermatitis. 2010 Jul-Aug Nutrition pmid:20579591
Ferrie S Re: The use of an inflammation-modulating diet in patients with acute lung injury or acute respiratory distress syndrome: a meta-analysis of outcome data. 2010 Jul-Aug JPEN J Parenter Enteral Nutr pmid:20631393
Itoh S et al. Antineoplastic effects of gamma linolenic Acid on hepatocellular carcinoma cell lines. 2010 J Clin Biochem Nutr pmid:20664735
Wang H et al. [Separation of gamma linolenic acid from evening primrose oil with urea inclusion--orthogonal experiment of optimizing technological parameters and observation of urea inclusion compound I]. 2010 Zhongguo Zhong Yao Za Zhi pmid:20707192
Abraham RD et al. Effects of safflower oil and evening primrose oil in men with a low dihomo-gamma-linolenic level. 1990 Atherosclerosis pmid:2112389
Khongto B et al. Fermentation process development of recombinant Hansenula polymorpha for gamma-linolenic acid production. 2010 J. Microbiol. Biotechnol. pmid:21124062
Li J et al. Feeding stimulant in Cinnamomum camphora for the common bluebottle, Graphium sarpedon nipponum (Lepidoptera: Papilionidae). 2010 Sep-Oct Z. Naturforsch., C, J. Biosci. pmid:21138058
Ghoreishi SM et al. Separation of γ-linolenic and other polyunsaturated fatty acids from Boraginaceae via supercritical CO2. 2011 J Sep Sci pmid:21246730
Hamilton LA and Trobaugh KA Acute respiratory distress syndrome: use of specialized nutrients in pediatric patients and infants. 2011 Nutr Clin Pract pmid:21266694
Enzenbach C et al. Erythrocyte membrane phospholipid polyunsaturated fatty acids are related to plasma C-reactive protein and adiponectin in middle-aged German women and men. 2011 Eur J Nutr pmid:21301856
Gamolenic acid in atopic eczema: Epogam. 1990 Drug Ther Bull pmid:2131219
Cameron M et al. Herbal therapy for treating rheumatoid arthritis. 2011 Cochrane Database Syst Rev pmid:21328257
Wan X et al. Molecular cloning and expression analysis of a delta 6-fatty acid desaturase gene from Rhizopus stolonifer strain YF6 which can accumulate high levels of gamma-linolenic acid. 2011 J. Microbiol. pmid:21369993
Al-Khamees WA et al. Status epilepticus associated with borage oil ingestion. 2011 J Med Toxicol pmid:21387119
Schumacher MC et al. A comparative study of tissue ω-6 and ω-3 polyunsaturated fatty acids (PUFA) in benign and malignant pathologic stage pT2a radical prostatectomy specimens. 2013 Urol. Oncol. pmid:21414816
Grau-Carmona T et al. Effect of an enteral diet enriched with eicosapentaenoic acid, gamma-linolenic acid and anti-oxidants on the outcome of mechanically ventilated, critically ill, septic patients. 2011 Clin Nutr pmid:21474219
Zaitone SA et al. Effect of evening primrose oil and ω-3 polyunsaturated fatty acids on the cardiovascular risk of celecoxib in rats. 2011 J. Cardiovasc. Pharmacol. pmid:21499116
Nakahara T et al. Inhibitory effects of mold oil including gamma-linolenate on platelet thrombus formation in mesenteric microvessels of the rat. 1990 Thromb. Res. pmid:2156348
Bordoni A [Significance and motivation of the clinical use of essential fatty acid derivatives, especially gamma-linolenic acid]. 1990 Clin Ter pmid:2158408
Jamal GA and Carmichael H The effect of gamma-linolenic acid on human diabetic peripheral neuropathy: a double-blind placebo-controlled trial. 1990 Diabet. Med. pmid:2159860
Kanbur M et al. The effects of evening primrose oil on lipid peroxidation induced by subacute aflatoxin exposure in mice. 2011 Food Chem. Toxicol. pmid:21600263
Sangeetha P et al. Free radical generation in human leukocytes by CIS-unsaturated fatty acids is a calmodulin dependent process. 1990 Prostaglandins Leukot. Essent. Fatty Acids pmid:2160083
Kawashima Y et al. Peroxisome proliferators enhance linoleic acid metabolism in rat liver. Increased biosynthesis of omega 6 polyunsaturated fatty acids. 1990 J. Biol. Chem. pmid:2160962
Melnik BC [A chance for the prevention of atopic diseases]. 1990 Monatsschr Kinderheilkd pmid:2162007
Hoppu U et al. Probiotics and dietary counselling targeting maternal dietary fat intake modifies breast milk fatty acids and cytokines. 2012 Eur J Nutr pmid:21626296
Macfarlane GJ et al. Evidence for the efficacy of complementary and alternative medicines in the management of rheumatoid arthritis: a systematic review. 2011 Rheumatology (Oxford) pmid:21652584
Pontes-Arruda A et al. Enteral nutrition with eicosapentaenoic acid, γ-linolenic acid and antioxidants in the early treatment of sepsis: results from a multicenter, prospective, randomized, double-blinded, controlled study: the INTERSEPT study. 2011 Crit Care pmid:21658240
Meyer BJ and Kolanu N Australian children are not consuming enough long-chain omega-3 polyunsaturated fatty acids for optimal health. 2011 Nov-Dec Nutrition pmid:21658909
Ikushima S et al. Gamma linolenic acid alters the cytotoxic activity of anticancer drugs on cultured human neuroblastoma cells. 1990 Jul-Aug Anticancer Res. pmid:2166461
Roemen TH et al. Quantitative assessment of gamma-linolenic acid in human blood and plasma with capillary gas chromatography. 1990 J. Chromatogr. pmid:2166745
Laho T et al. Effects of prefermented cereal-derived substrates (ground barley and rye bran) enriched with fungal γ-linolenic acid on rumen fermentation parameters and lipid metabolism in vitro. 2011 J. Appl. Microbiol. pmid:21672096
Chen Q et al. Delta-6 desaturase from borage converts linoleic acid to gamma-linolenic acid in HEK293 cells. 2011 Biochem. Biophys. Res. Commun. pmid:21679695
Wang P et al. Production of γ-linolenic acid using a novel heterologous expression system in the oleaginous yeast Lipomyces kononenkoae. 2011 Biotechnol. Lett. pmid:21681556
Wiedemann HP Fish oil is not the fix for acute lung injury. 2011 Crit. Care Med. pmid:21685749
Cleland LG et al. The effect of dietary fish oil supplement upon the content of dihomo-gammalinolenic acid in human plasma phospholipids. 1990 Prostaglandins Leukot. Essent. Fatty Acids pmid:2169063
Liu J et al. Δ6-Desaturase from Mortierella alpina: cDNA cloning, expression, and phylogenetic analysis. 2011 Biotechnol. Lett. pmid:21691840
van der Merwe CF et al. The effect of gamma-linolenic acid, an in vitro cytostatic substance contained in evening primrose oil, on primary liver cancer. A double-blind placebo controlled trial. 1990 Prostaglandins Leukot. Essent. Fatty Acids pmid:2169638
Alhazzaa R et al. Up-regulated desaturase and elongase gene expression promoted accumulation of polyunsaturated fatty acid (PUFA) but not long-chain PUFA in Lates calcarifer, a tropical euryhaline fish, fed a stearidonic acid- and γ-linoleic acid-enriched diet. 2011 J. Agric. Food Chem. pmid:21707030