Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.
To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Guenther L and Wexler D | Efamol in the treatment of atopic dermatitis. | 1987 | J. Am. Acad. Dermatol. | pmid:3680673 |
Ziboh VA and Chapkin RS | Biologic significance of polyunsaturated fatty acids in the skin. | 1987 | Arch Dermatol | pmid:3688908 |
Singh NK et al. | Essential fatty acids and cancer with particular reference to Hodgkin's disease. | 1987 | J Assoc Physicians India | pmid:3693269 |
Das UN et al. | Beneficial effect of essential fatty acids in cirrhosis of the liver. | 1987 | J Assoc Physicians India | pmid:3693270 |
Levy RJ and Lian JB | gamma-Carboxyglutamate excretion and warfarin therapy. | 1979 | Clin. Pharmacol. Ther. | pmid:373941 |
Sugano M et al. | Hypocholesterolemic effect of gamma-linolenic acid as evening primrose oil in rats. | 1986 | Ann. Nutr. Metab. | pmid:3752928 |
Puolakka J et al. | Biochemical and clinical effects of treating the premenstrual syndrome with prostaglandin synthesis precursors. | 1985 | J Reprod Med | pmid:3839018 |
Wright S | Atopic dermatitis and essential fatty acids: a biochemical basis for atopy? | 1985 | Acta Derm Venereol Suppl (Stockh) | pmid:3890448 |
Bamford JT et al. | Atopic eczema unresponsive to evening primrose oil (linoleic and gamma-linolenic acids). | 1985 | J. Am. Acad. Dermatol. | pmid:3908514 |
Kumar S et al. | Prediction of response to endocrine therapy in pronounced cyclical mastalgia using dynamic tests of prolactin release. | 1985 | Clin. Endocrinol. (Oxf) | pmid:3938354 |
Soma M et al. | The effects of hydrogenated coconut oil, safflower oil, and evening primrose oil on development of hypertension and sodium handling in spontaneously hypertensive rats. | 1985 | Can. J. Physiol. Pharmacol. | pmid:4005704 |
Webb J and McCredie M | Primary Sjögren's syndrome treated with Efamol/efavit. A double-blind cross-over investigation. | 1985 | Rheumatol. Int. | pmid:4048763 |
Belch JJ et al. | Evening primrose oil (Efamol) in the treatment of Raynaud's phenomenon: a double blind study. | 1985 | Thromb. Haemost. | pmid:4082084 |
Strong AM et al. | The effect of oral linoleic acid and gamma-linolenic acid (Efamol [G]). | 1985 Nov-Dec | Br J Clin Pract | pmid:4092010 |
Horrobin DF | Essential fatty acid metabolism in diseases of connective tissue with special reference to scleroderma and to Sjogren's syndrome. | 1984 | Med. Hypotheses | pmid:6088955 |
Mertin J | Omega-6 and omega-3 polyunsaturates and the immune system. | 1984 | Br J Clin Pract Suppl | pmid:6091715 |
Leonard BE | Possible relationships between thiamine, carnitine, polyunsaturated fatty acids and the neurotoxicity of alcohol. | 1984 | Alcohol Alcohol. | pmid:6093831 |
Traitler H et al. | Characterization of gamma-linolenic acid in Ribes seed. | 1984 | Lipids | pmid:6098796 |
Monnier L | [Influence of metabolic and nutritional balance on platelet function in insulin-dependent diabetes]. | 1984 | Journ Annu Diabetol Hotel Dieu | pmid:6100381 |
Lovell CR et al. | Treatment of atopic eczema with evening primrose oil. | 1981 | Lancet | pmid:6109930 |
Wright S and Burton JL | Oral evening-primrose-seed oil improves atopic eczema. | 1982 | Lancet | pmid:6128449 |
Chalmers RJ and Shuster S | Evening primrose seed oil in ichthyosis vulgaris. | 1983 | Lancet | pmid:6130264 |
Horrobin DF | A biochemical basis for alcoholism and alcohol-induced damage including the fetal alcohol syndrome and cirrhosis: interference with essential fatty acid and prostaglandin metabolism. | 1980 | Med. Hypotheses | pmid:6253773 |
Darcet P et al. | [Study of the metabolism of fatty acids and total plasma lipids, and platelet aggregation of a population of elderly men using a diet enriched in gamma-linolenic acid]. | 1980 | Ann Nutr Aliment | pmid:6254419 |
Beitz J et al. | Influence of linseed oil diet on the pattern of serum phospholipids in man. | 1981 | Acta Biol. Med. Ger. | pmid:6277115 |
Bodak A et al. | [Comparative study of light and electron microscopic aspects of myocardial lesions induced in the rat by oils with several amounts of gamma-linolenic acid (author's transl)]. | 1982 | Pathol. Biol. | pmid:6278382 |
Bonacossa A et al. | Effect of corticosterone, hydrocortisone and prostaglandin fatty acid precursors on the spontaneous motility of the uterus isolated from ovariectomized rats. | 1982 | Prostaglandins | pmid:6278538 |
Huang YS et al. | Most biological effects of zinc deficiency corrected by gamma-linolenic acid (18: 3 omega 6) but not by linoleic acid (18: 2 omega 6). | 1982 | Atherosclerosis | pmid:6279122 |
Simmons DA et al. | Significance of tissue myo-inositol concentrations in metabolic regulation in nerve. | 1982 | Science | pmid:6285474 |
Varma PK and Persaud TV | Protection against ethanol-induced embryonic damage by administering gamma-linolenic and linoleic acids. | 1982 | Prostaglandins Leukot Med | pmid:6287501 |
Leary WP et al. | Some effects of gamma-linolenic acid on cultured human oesophageal carcinoma cells. | 1982 | S. Afr. Med. J. | pmid:6291175 |
Dippenaar N et al. | The reversibility of cancer: evidence that malignancy in human hepatoma cells is gamma-linolenic acid deficiency-dependent. | 1982 | S. Afr. Med. J. | pmid:6291176 |
Renaud S et al. | Comparative beneficial effects on platelet functions and atherosclerosis of dietary linoleic and gamma-linolenic acids in the rabbit. | 1982 | Atherosclerosis | pmid:6297517 |
van der Merwe CF | The reversibility of cancer. | 1983 | S. Afr. Med. J. | pmid:6298954 |
Field EJ and Joyce G | Multiple sclerosis: effect of gamma linolenate administration upon membranes and the need for extended clinical trials of unsaturated fatty acids. | 1983 | Eur. Neurol. | pmid:6301844 |
Hansen TM et al. | Treatment of rheumatoid arthritis with prostaglandin E1 precursors cis-linoleic acid and gamma-linolenic acid. | 1983 | Scand. J. Rheumatol. | pmid:6304871 |
Botha JH et al. | Parenteral gamma-linolenic acid administration in nude mice bearing a range of human tumour xenografts. | 1983 | S. Afr. Med. J. | pmid:6304925 |
Paccalin J et al. | [Changes in the higher derivatives of linoleic acid in cirrhotics treated with gamma-linolenic acid]. | 1983 May-Jun | Therapie | pmid:6310813 |
Kirstein D et al. | Effect of dietary fats on the delta 6- and delta 5-desaturation of fatty acids in rat liver microsomes. | 1983 | Br. J. Nutr. | pmid:6315055 |
Kemp P and Lander DJ | The hydrogenation of gamma-linolenic acid by pure cultures of two rumen bacteria. | 1983 | Biochem. J. | pmid:6318740 |
Hamberg M | Omega 6-oxygenation of 6, 9, 12-octadecatrienoic acid in human platelets. | 1983 | Biochem. Biophys. Res. Commun. | pmid:6318765 |
Van der Merwe CF | The reversibility of cancer. | 1984 | S. Afr. Med. J. | pmid:6320476 |
Booyens J and Katzeff IE | Cancer: a simple metabolic disease? | 1983 | Med. Hypotheses | pmid:6321917 |
Hamberg M | Isotope effects in enzymatic and non-enzymatic oxygenation of 6,9,12-octadecatrienoic acid. | 1984 | Biochim. Biophys. Acta | pmid:6322853 |
Chaintreuil J et al. | Effects of dietary gamma-linolenate supplementation on serum lipids and platelet function in insulin-dependent diabetic patients. | 1984 | Hum Nutr Clin Nutr | pmid:6323358 |
Mills DE and Ward R | Attenuation of psychosocial stress-induced hypertension by gamma-linolenic acid (GLA) administration in rats. | 1984 | Proc. Soc. Exp. Biol. Med. | pmid:6324224 |
Booyens J and Koenig L | The effect of dietary supplementation with gamma-linolenic acid on the growth of induced tumours in rats. | 1984 | S. Afr. Med. J. | pmid:6324397 |
Paccalin J et al. | [Rediscovery of an oleaginous plant: Oenothera biennis. The importance of gamma-linolenic acid in nutrition]. | 1983 | Bull. Acad. Natl. Med. | pmid:6324965 |
McCarty MF and Rubin EJ | Rationales for micronutrient supplementation in diabetes. | 1984 | Med. Hypotheses | pmid:6325854 |
van der Merwe CF | The reversibility of cancer. | 1984 | S. Afr. Med. J. | pmid:6326340 |