Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.
To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Umeda-Sawada R et al. | Distribution and metabolism of dihomo-gamma-linolenic acid (DGLA, 20:3n-6) by oral supplementation in rats. | 2006 | Biosci. Biotechnol. Biochem. | pmid:16960355 |
Kim J et al. | Comparative effect of gromwell (Lithospermum erythrorhizon) extract and borage oil on reversing epidermal hyperproliferation in guinea pigs. | 2006 | Biosci. Biotechnol. Biochem. | pmid:16960390 |
Hatanaka E et al. | Systematic study on ROS production induced by oleic, linoleic, and gamma-linolenic acids in human and rat neutrophils. | 2006 | Free Radic. Biol. Med. | pmid:16962937 |
Hongsthong A et al. | Revealing the complementation of ferredoxin by cytochrome b (5) in the Spirulina- (6)-desaturation reaction by N-terminal fusion and co-expression of the fungal-cytochrome b (5) domain and Spirulina- (6)-acyl-lipid desaturase. | 2006 | Appl. Microbiol. Biotechnol. | pmid:16575563 |
Das UN | Re: Effect of gamma-linolenic acid on the transcriptional activity of the Her-2/neu (erbB-2) oncogene. | 2006 | J. Natl. Cancer Inst. | pmid:16705127 |
Puri BK | Long-chain polyunsaturated fatty acids and the pathophysiology of myalgic encephalomyelitis (chronic fatigue syndrome). | 2007 | J. Clin. Pathol. | pmid:16935966 |
Noli C et al. | Conjugated linoleic acid and black currant seed oil in the treatment of canine atopic dermatitis: a preliminary report. | 2007 | Vet. J. | pmid:16495095 |
Dasgupta S and Bhattacharyya DK | Dietary effect of gamma-linolenic acid on the lipid profile of rat fed erucic acid rich oil. | 2007 | J Oleo Sci | pmid:17938547 |
Sýkora J et al. | High-performance liquid chromatography with nuclear magnetic resonance detection--A method for quantification of alpha- and gamma-linolenic acids in their mixtures with free fatty acids. | 2007 | J Chromatogr A | pmid:17157864 |
Martin TA et al. | Enhanced tight junction function in human breast cancer cells by antioxidant, selenium and polyunsaturated lipid. | 2007 | J. Cell. Biochem. | pmid:17243118 |
Matta JA et al. | TRPV1 is a novel target for omega-3 polyunsaturated fatty acids. | 2007 | J. Physiol. (Lond.) | pmid:17038422 |
Pitel S et al. | At low doses, a gamma-linolenic acid-lipoic acid conjugate is more effective than docosahexaenoic acid-enriched phospholipids in preventing neuropathy in diabetic rats. | 2007 | J. Nutr. | pmid:17237313 |
Christie A et al. | Effectiveness of nonpharmacological and nonsurgical interventions for patients with rheumatoid arthritis: an overview of systematic reviews. | 2007 | Phys Ther | pmid:17906290 |
Dobryniewski J et al. | [The gamma-linolenic acid (GLA)--the therapeutic value]. | 2007 | Prz. Lek. | pmid:17892041 |
Theilla M et al. | A diet enriched in eicosapentanoic acid, gamma-linolenic acid and antioxidants in the prevention of new pressure ulcer formation in critically ill patients with acute lung injury: A randomized, prospective, controlled study. | 2007 | Clin Nutr | pmid:17933438 |
Garaiova I et al. | A randomised cross-over trial in healthy adults indicating improved absorption of omega-3 fatty acids by pre-emulsification. | 2007 | Nutr J | pmid:17254329 |
Das UN | Gamma-linolenic acid therapy of human glioma-a review of in vitro, in vivo, and clinical studies. | 2007 | Med. Sci. Monit. | pmid:17599036 |
Schirmer MA and Phinney SD | Gamma-linolenate reduces weight regain in formerly obese humans. | 2007 | J. Nutr. | pmid:17513402 |
Curtis L | High-quality enteral nutrition essential for reducing morbidity and mortality in acute care patients. | 2007 | Crit. Care Med. | pmid:17421112 |
Ortiz-Leyba C and Garnacho-Montero J | Saving lives in severe sepsis with the help of enteral nutrition. | 2007 | Crit. Care Med. | pmid:17421113 |
Kanehara S et al. | Clinical effects of undershirts coated with borage oil on children with atopic dermatitis: a double-blind, placebo-controlled clinical trial. | 2007 | J. Dermatol. | pmid:18078406 |
Vrinten P et al. | Production of polyunsaturated fatty acids in transgenic plants. | 2007 | Biotechnol. Genet. Eng. Rev. | pmid:18059637 |
Villamor E et al. | Long-chain n-6 polyunsaturated fatty acids in breast milk decrease the risk of HIV transmission through breastfeeding. | 2007 | Am. J. Clin. Nutr. | pmid:17823433 |
Stolyhwo A and Mol J | Changes in the content of gamma-linolenic C18:3 (n-6) and stearidonic C18:4 (n-3) acids in developing seeds of viper's bugloss Echium vulgare L. | 2007 | Acta Biochim. Pol. | pmid:18066400 |
Saied GM et al. | Low intensity laser therapy is comparable to bromocriptine-evening primrose oil for the treatment of cyclical mastalgia in Egyptian females. | 2007 | Tanzan Health Res Bull | pmid:18087899 |
Poulsen RC et al. | Specific effects of gamma-linolenic, eicosapentaenoic, and docosahexaenoic ethyl esters on bone post-ovariectomy in rats. | 2007 | Calcif. Tissue Int. | pmid:18008020 |
Lindmark L and Clough P | A 5-month open study with long-chain polyunsaturated fatty acids in dyslexia. | 2007 | J Med Food | pmid:18158838 |
Guo SX et al. | [Influence of methyl esterification on the ultraviolet absorption of gamma-linolenic acid]. | 2007 | Zhong Yao Cai | pmid:18236761 |
Puri BK | The safety of evening primrose oil in epilepsy. | 2007 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:17764919 |
Pinna A et al. | Effect of oral linoleic and gamma-linolenic acid on meibomian gland dysfunction. | 2007 | Cornea | pmid:17413949 |
Lu H et al. | [Cloning and expression of a delta6-fatty acid desaturase gene from Rhizopus stolonifer in Saccharomyces cervisiae]. | 2007 | Wei Sheng Wu Xue Bao | pmid:17436625 |
Cho HS et al. | Anti-wrinkling effects of the mixture of vitamin C, vitamin E, pycnogenol and evening primrose oil, and molecular mechanisms on hairless mouse skin caused by chronic ultraviolet B irradiation. | 2007 | Photodermatol Photoimmunol Photomed | pmid:17803593 |
Kanehara S et al. | Undershirts coated with borage oil alleviate the symptoms of atopic dermatitis in children. | 2007 Sep-Oct | Eur J Dermatol | pmid:17673396 |
Yen CH et al. | Linoleic acid metabolite levels and transepidermal water loss in children with atopic dermatitis. | 2008 | Ann. Allergy Asthma Immunol. | pmid:18254485 |
Bloom P | Atopic dermatitis: the quest for the silver bullet. | 2008 | Vet. J. | pmid:18554562 |
Adam O | [Ankylosing Spondylitis and convenient nutrition]. | 2008 | Wien Med Wochenschr | pmid:18560957 |
Wedig KE and Whitsett JA | Down the primrose path: petechiae in a neonate exposed to herbal remedy for parturition. | 2008 | J. Pediatr. | pmid:18154917 |
Nasrollahzadeh J et al. | The influence of feeding linoleic, gamma-linolenic and docosahexaenoic acid rich oils on rat brain tumor fatty acids composition and fatty acid binding protein 7 mRNA expression. | 2008 | Lipids Health Dis | pmid:19014610 |
Shi LM et al. | [Effects of gamma linolenic acid on atherosclerosis induced by cholesterol-rich diet in rats]. | 2008 | Zhongguo Zhong Yao Za Zhi | pmid:19260318 |
Nandakumar M and Tan MW | Gamma-linolenic and stearidonic acids are required for basal immunity in Caenorhabditis elegans through their effects on p38 MAP kinase activity. | 2008 | PLoS Genet. | pmid:19023415 |
Won J et al. | Stability analysis of zinc oxide-nanoencapsulated conjugated linoleic acid and gamma-linolenic acid. | 2008 | J. Food Sci. | pmid:19019122 |
Geppert J et al. | Co-supplementation of healthy women with fish oil and evening primrose oil increases plasma docosahexaenoic acid, gamma-linolenic acid and dihomo-gamma-linolenic acid levels without reducing arachidonic acid concentrations. | 2008 | Br. J. Nutr. | pmid:17678567 |
Rühl R et al. | Fatty acid composition of serum lipid classes in mice following allergic sensitisation with or without dietary docosahexaenoic acid-enriched fish oil substitution. | 2008 | Br. J. Nutr. | pmid:18005485 |
Chilton FH et al. | Mechanisms by which botanical lipids affect inflammatory disorders. | 2008 | Am. J. Clin. Nutr. | pmid:18258646 |
Surette ME et al. | The impact of a medical food containing gammalinolenic and eicosapentaenoic acids on asthma management and the quality of life of adult asthma patients. | 2008 | Curr Med Res Opin | pmid:18194593 |
Cui PH et al. | Monoepoxy octadecadienoates and monoepoxy octadecatrienoates 1: NMR spectral characterization. | 2008 | Chem. Phys. Lipids | pmid:18339314 |
Wu CC et al. | Metabolism of omega-6 polyunsaturated fatty acids in women with dysmenorrhea. | 2008 | Asia Pac J Clin Nutr | pmid:18296341 |
Jeennor S et al. | Evaluation of inoculum performance for enhancing gamma-linolenic acid production from Mucor rouxii. | 2008 | Lett. Appl. Microbiol. | pmid:18298455 |
Puch F et al. | Consumption of functional fermented milk containing borage oil, green tea and vitamin E enhances skin barrier function. | 2008 | Exp. Dermatol. | pmid:18318715 |
Vinggaard AM et al. | Screening of 397 chemicals and development of a quantitative structure--activity relationship model for androgen receptor antagonism. | 2008 | Chem. Res. Toxicol. | pmid:18324785 |