Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.
To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Nassar BA et al. | The influence of dietary marine oil (Polepa) and evening primrose oil (Efamol) on prostaglandin production by the rat mesenteric vasculature. | 1987 | Prostaglandins Leukot Med | pmid:3033691 |
Cunnane SC | Hepatic triacylglycerol accumulation induced by ethanol and carbon tetrachloride: interactions with essential fatty acids and prostaglandins. | 1987 | Alcohol. Clin. Exp. Res. | pmid:3032013 |
Horrobin DF | Essential fatty acids, prostaglandins, and alcoholism: an overview. | 1987 | Alcohol. Clin. Exp. Res. | pmid:3032012 |
Huang YS et al. | Protective effect of gamma-linolenic acid on aspirin-induced gastric hemorrhage in rats. | 1987 | Digestion | pmid:3030865 |
Bursztyn PG and King MH | Fat induced hypertension in rabbits: the effects of dietary linoleic and linolenic acid. | 1986 | J. Hypertens. | pmid:3029216 |
Viikari J and Lehtonen A | Effect of primrose oil on serum lipids and blood pressure in hyperlipidemic subjects. | 1986 | Int J Clin Pharmacol Ther Toxicol | pmid:3028968 |
Stymne S and Stobart AK | Biosynthesis of gamma-linolenic acid in cotyledons and microsomal preparations of the developing seeds of common borage (Borago officinalis). | 1986 | Biochem. J. | pmid:3028375 |
Dib A and Carreau JP | Effects of gamma-linolenic acid supplementation on lipogenesis regulation in pregnant zinc-deficient rat and fetus. | 1986 | Int. J. Biochem. | pmid:3026865 |
Fujiwara F et al. | Antitumor effect of gamma-linolenic acid on cultured human neuroblastoma cells. | 1986 | Prostaglandins Leukot Med | pmid:3020590 |
Bégin ME and Das UN | A deficiency in dietary gamma-linolenic and/or eicosapentaenoic acids may determine individual susceptibility to AIDS. | 1986 | Med. Hypotheses | pmid:3014282 |
Skogh M | Atopic eczema unresponsive to evening primrose oil (linoleic and gamma-linolenic acids) | 1986 | J. Am. Acad. Dermatol. | pmid:3013957 |
Wolkin A et al. | Essential fatty acid supplementation in tardive dyskinesia. | 1986 | Am J Psychiatry | pmid:3013033 |
Robinson KM and Botha JH | Effects of gamma-linolenic acid, dihomo-gamma-linolenic acid and ethanol on cultured human mammary carcinoma cells. | 1985 | Prostaglandins Leukot Med | pmid:2999828 |
Wainwright P et al. | gamma-Linolenic acid fails to prevent the effects of prenatal ethanol exposure on brain and behavioral development in B6D2F2 mice. | 1985 Jul-Aug | Alcohol. Clin. Exp. Res. | pmid:2996378 |
Booyens J et al. | The use of drugs for the inhibition of prostaglandin or leukotriene synthesis from arachidonic acid is theoretically hazardous. | 1985 | Med. Hypotheses | pmid:2995775 |
Mills DE et al. | Gamma linolenic acid attenuates cardiovascular responses to stress in borderline hypertensive rats. | 1985 | Lipids | pmid:2995750 |
de Bravo MM et al. | Metabolism of gammalinolenic acid by human blood platelet microsomes. | 1985 | Biochem. Int. | pmid:2994669 |
Das UN et al. | Prostaglandins and their precursors can modify genetic damage-induced by gamma-radiation and benzo(a)pyrene. | 1985 | Prostaglandins | pmid:2994175 |
Segarnick DJ et al. | Prostanoid modulation (mediation?) of certain behavioral effects of ethanol. | 1985 | Pharmacol. Biochem. Behav. | pmid:2994122 |
Botha JH et al. | The response of human carcinoma cell lines to gamma-linolenic acid with special reference to the effects of agents which influence prostaglandin and thromboxane synthesis. | 1985 | Prostaglandins Leukot Med | pmid:2994114 |
Segarnick DJ et al. | Gamma-linolenic acid inhibits the development of the ethanol-induced fatty liver. | 1985 | Prostaglandins Leukot Med | pmid:2986177 |
O'Brien PM et al. | The effect of dietary supplementation with linoleic and gammalinolenic acids on the pressor response to angiotensin II--a possible role in pregnancy-induced hypertension? | 1985 | Br J Clin Pharmacol | pmid:2985102 |
Pascaud M and Strouve-Vallet C | Desaturation of 14C linoleic acid by the rat fetus. | 1985 | Ann. Nutr. Metab. | pmid:2983600 |
Choi YS and Sugano M | Effects of dietary alpha- and gamma-linolenic acid on lipid metabolism in young and adult rats. | 1988 | Ann. Nutr. Metab. | pmid:2903713 |
Meigel W et al. | [Additional oral therapy of atopic dermatitis with unsaturated fatty acids]. | 1987 | Z. Hautkr. | pmid:2894730 |
Jamal GA et al. | Gamma-linolenic acid in diabetic neuropathy. | 1986 | Lancet | pmid:2871365 |
pmid:28686292 | ||||
Bégin ME et al. | Selective killing of human cancer cells by polyunsaturated fatty acids. | 1985 | Prostaglandins Leukot Med | pmid:2864701 |
pmid:28646265 | ||||
Khattab HAH et al. | EFFICIENCY OF BORAGE SEEDS OIL AGAINST GAMMA IRRADIATION-INDUCED HEPATOTOXICITY IN MALE RATS: POSSIBLE ANTIOXIDANT ACTIVITY. | 2017 | Afr J Tradit Complement Altern Med | pmid:28638880 |
pmid:28637686 | ||||
pmid:28637506 | ||||
Pye JK et al. | Clinical experience of drug treatments for mastalgia. | 1985 | Lancet | pmid:2862523 |
Huang YS et al. | Effect of dietary alpha- and gamma-linolenic acid on tissue fatty acids in guinea pigs. | 1985 | Proc. Soc. Exp. Biol. Med. | pmid:2857052 |
pmid:28557429 | ||||
pmid:28545346 | ||||
Julu PO | Essential fatty acids prevent slowed nerve conduction in streptozotocin diabetic rats. | 1988 Oct-Dec | J Diabet Complications | pmid:2853165 |
pmid:28528342 | ||||
pmid:28526097 | ||||
Williams JH | The use of gamma linolenic acid, linoleic acid and natural vitamin E for the treatment of multicentric lymphoma in two dogs. | 1988 | J S Afr Vet Assoc | pmid:2848946 |
Tate GA et al. | Suppression of monosodium urate crystal-induced acute inflammation by diets enriched with gamma-linolenic acid and eicosapentaenoic acid. | 1988 | Arthritis Rheum. | pmid:2848532 |
Cronholm T et al. | Influence of dietary fats on pancreatic phospholipids of chronically ethanol-treated rats. | 1988 | Lipids | pmid:2846981 |
Miller CC and Ziboh VA | Gammalinolenic acid-enriched diet alters cutaneous eicosanoids. | 1988 | Biochem. Biophys. Res. Commun. | pmid:2841938 |
Daneshmand R et al. | Associations of estimated Δ-5-desaturase and Δ-6-desaturase activities with stroke risk factors and risk of stroke: the Kuopio Ischaemic Heart Disease Risk Factor Study. | 2017 | Br. J. Nutr. | pmid:28382895 |
Van der Merwe CF et al. | Oral gamma-linolenic acid in 21 patients with untreatable malignancy. An ongoing pilot open clinical trial. | 1987 | Br J Clin Pract | pmid:2837264 |
Chaud M et al. | Gamma-linolenic acid improves the constancy of contractions in uteri from sprayed rats and is metabolized to prostaglandin E1 but not to bisenoic prostanoids. | 1988 | Prostaglandins | pmid:2836889 |
Veselinovic M et al. | Clinical Benefits of n-3 PUFA and ɤ-Linolenic Acid in Patients with Rheumatoid Arthritis. | 2017 | Nutrients | pmid:28346333 |
pmid:28336102 | ||||
Belch JJ et al. | Effects of altering dietary essential fatty acids on requirements for non-steroidal anti-inflammatory drugs in patients with rheumatoid arthritis: a double blind placebo controlled study. | 1988 | Ann. Rheum. Dis. | pmid:2833184 |
Fujiwara F et al. | Fatty acid modification of cultured neuroblastoma cells by gamma linolenic acid relevant to its antitumor effect. | 1987 | Prostaglandins Leukot Med | pmid:2829239 |