| MeSH term | MeSH ID | Detail |
|---|---|---|
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Diabetes Mellitus, Experimental | D003921 | 85 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Gastritis | D005756 | 27 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Osteosarcoma | D012516 | 50 associated lipids |
| Melanoma | D008545 | 69 associated lipids |
| Kidney Calculi | D007669 | 7 associated lipids |
gamma-Linolenic acid
Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.
Cross Reference
Introduction
To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid
PubChem Associated disorders and diseases
What pathways are associated with gamma-Linolenic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with gamma-Linolenic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with gamma-Linolenic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
What genes are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
What common seen animal models are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with gamma-Linolenic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Jiang WG et al. | Peroxisome proliferator activated receptor-gamma (PPAR-gamma) mediates the action of gamma linolenic acid in breast cancer cells. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10780877 |
| Leonard AE et al. | cDNA cloning and characterization of human Delta5-desaturase involved in the biosynthesis of arachidonic acid. | 2000 | Biochem. J. | pmid:10769175 |
| Preuss M et al. | Role of antioxidant enzyme expression in the selective cytotoxic response of glioma cells to gamma-linolenic acid supplementation. | 2000 | Free Radic. Biol. Med. | pmid:10832077 |
| Palombo JD et al. | Comparison of growth and fatty acid metabolism in rats fed diets containing equal levels of gamma-linolenic acid from high gamma-linolenic acid canola oil or borage oil. | 2000 | Lipids | pmid:11026618 |
| Fokkema MR et al. | Short-term supplementation of low-dose gamma-linolenic acid (GLA), alpha-linolenic acid (ALA), or GLA plus ALA does not augment LCP omega 3 status of Dutch vegans to an appreciable extent. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11090255 |
| Worm M and Henz BM | Novel unconventional therapeutic approaches to atopic eczema. | 2000 | Dermatology (Basel) | pmid:11096188 |
| Harbige LS et al. | The protective effects of omega-6 fatty acids in experimental autoimmune encephalomyelitis (EAE) in relation to transforming growth factor-beta 1 (TGF-beta1) up-regulation and increased prostaglandin E2 (PGE2) production. | 2000 | Clin. Exp. Immunol. | pmid:11122253 |
| Horner NK and Lampe JW | Potential mechanisms of diet therapy for fibrocystic breast conditions show inadequate evidence of effectiveness. | 2000 | J Am Diet Assoc | pmid:11103660 |
| Pakala R et al. | Vascular smooth muscle cells preloaded with eicosapentaenoic acid and docosahexaenoic acid fail to respond to serotonin stimulation. | 2000 | Atherosclerosis | pmid:11058699 |
| Vinik AI et al. | Diabetic neuropathies. | 2000 | Diabetologia | pmid:10990072 |
| Iijima S et al. | Oral supplementation with gamma-linolenic acid extracted from Mucor circinelloides improves the deformability of red blood cells in hemodialysis patients. | 2000 | Nephron | pmid:11014980 |
| Arnold LE et al. | Does zinc moderate essential fatty acid and amphetamine treatment of attention-deficit/hyperactivity disorder? | 2000 | J Child Adolesc Psychopharmacol | pmid:10933121 |
| Guil-Guerrero JL et al. | Occurrence and characterization of oils rich in gamma-linolenic acid part II: fatty acids and squalene from Macaronesian Echium leaves. | 2000 | Phytochemistry | pmid:10939357 |
| Liu QY and Tan BK | Effects of cis-unsaturated fatty acids on doxorubicin sensitivity in P388/DOX resistant and P388 parental cell lines. | 2000 | Life Sci. | pmid:10954054 |
| Parker-Barnes JM et al. | Identification and characterization of an enzyme involved in the elongation of n-6 and n-3 polyunsaturated fatty acids. | 2000 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10899997 |
| Rahbeeni F et al. | The effect of evening primrose oil on the radiation response and blood flow of mouse normal and tumour tissue. | 2000 | Int. J. Radiat. Biol. | pmid:10902742 |
| Kapoor R and Klimaszewski A | Efficacy of borage oil in patients with atopic eczema. | 2000 | Br. J. Dermatol. | pmid:10886164 |
| Simán CM et al. | Failure of short-term gamma-linolenic acid treatment to reduce urinary calcium loss of diabetic rats. | 2000 | Urol. Res. | pmid:10850637 |
| Murray MJ et al. | Effects of eicosapentaenoic and gamma-linolenic acids (dietary lipids) on pulmonary surfactant composition and function during porcine endotoxemia. | 2000 | Chest | pmid:10858408 |
| Oguogho A et al. | Prostaglandin synthesis in human lymphatics from precursor fatty acids. | 2000 | Lymphology | pmid:10897472 |
| Barham JB et al. | Addition of eicosapentaenoic acid to gamma-linolenic acid-supplemented diets prevents serum arachidonic acid accumulation in humans. | 2000 | J. Nutr. | pmid:10917903 |
| Guil-Guerrero JL et al. | Occurrence and characterization of oils rich in gamma-linolenic acid Part I: Echium seeds from Macaronesia. | 2000 | Phytochemistry | pmid:10731022 |
| Hindo J et al. | Evidence of the formation of different hydroperoxides in irradiated gamma-linolenate solutions: effect of micelle formation. | 2000 | Radiat. Res. | pmid:10629620 |
| Takahashi Y et al. | Dietary gamma-linolenic acid in the form of borage oil causes less body fat accumulation accompanying an increase in uncoupling protein 1 mRNA level in brown adipose tissue. | 2000 | Comp. Biochem. Physiol. B, Biochem. Mol. Biol. | pmid:11079375 |
| Dobson G | Leaf lipids of Ribes nigrum: a plant containing 16:3, alpha-18:3, gamma-18:3 and 18:4 fatty acids. | 2000 | Biochem. Soc. Trans. | pmid:11171133 |
| Beaudoin F et al. | Production of C20 polyunsaturated fatty acids (PUFAs) by pathway engineering: identification of a PUFA elongase component from Caenorhabditis elegans. | 2000 | Biochem. Soc. Trans. | pmid:11171161 |
| Shahidi F | Antioxidant factors in plant foods and selected oilseeds. | 2000 | Biofactors | pmid:11237180 |
| Horrobin DF | Essential fatty acid metabolism and its modification in atopic eczema. | 2000 | Am. J. Clin. Nutr. | pmid:10617999 |
| Petrik MB et al. | Highly unsaturated (n-3) fatty acids, but not alpha-linolenic, conjugated linoleic or gamma-linolenic acids, reduce tumorigenesis in Apc(Min/+) mice. | 2000 | J. Nutr. | pmid:11015469 |
| Chan LW et al. | Microencapsulation of oils using sodium alginate. | 2000 Nov-Dec | J Microencapsul | pmid:11063422 |
| Fuller MA et al. | Activity of soybean lipoxygenase isoforms against esterified fatty acids indicates functional specificity. | 2001 | Arch. Biochem. Biophys. | pmid:11361131 |
| Kamphuis MM et al. | Fat-specific satiety in humans for fat high in linoleic acid vs fat high in oleic acid. | 2001 | Eur J Clin Nutr | pmid:11423927 |
| Chakrabarti KB et al. | Modification of doxorubicin-induced cardiotoxicity: effect of essential fatty acids and ICRF-187 (dexrazoxane). | 2001 | Eur. J. Cancer | pmid:11435077 |
| Banni S et al. | Vaccenic acid feeding increases tissue levels of conjugated linoleic acid and suppresses development of premalignant lesions in rat mammary gland. | 2001 | Nutr Cancer | pmid:12094634 |
| OlguÃn EJ et al. | The effect of low light flux and nitrogen deficiency on the chemical composition of Spirulina sp. (Arthrospira) grown on digested pig waste. | 2001 | Bioresour. Technol. | pmid:11211071 |
| Goffman FD and Galletti S | Gamma-linolenic acid and tocopherol contents in the seed oil of 47 accessions from several Ribes species. | 2001 | J. Agric. Food Chem. | pmid:11170598 |
| Conti E et al. | gamma-Linolenic acid production by solid-state fermentation of Mucorales strains on cereals. | 2001 | Bioresour. Technol. | pmid:11198184 |
| Keysser G | [Are there effective dietary recommendations for patients with rheumatoid arthritis?]. | 2001 | Z Rheumatol | pmid:11263011 |
| Biessels GJ et al. | The effect of gamma-linolenic acid-alpha-lipoic acid on functional deficits in the peripheral and central nervous system of streptozotocin-diabetic rats. | 2001 | J. Neurol. Sci. | pmid:11137514 |
| Corbett JW et al. | Trifluoromethyl-containing 3-alkoxymethyl- and 3-aryloxymethyl-2-pyridinones are potent inhibitors of HIV-1 non-nucleoside reverse transcriptase. | 2001 | Bioorg. Med. Chem. Lett. | pmid:11212098 |
| Birch AE et al. | Antioxidant properties of evening primrose seed extracts. | 2001 | J. Agric. Food Chem. | pmid:11559161 |
| Demmelmair H et al. | Influence of formulas with borage oil or borage oil plus fish oil on the arachidonic acid status in premature infants. | 2001 | Lipids | pmid:11485158 |
| Guil-Guerrero JL et al. | Occurrence and characterization of oils rich in gamma-linolenic acid (III): the taxonomical value of the fatty acids in Echium (Boraginaceae). | 2001 | Phytochemistry | pmid:11524120 |
| Ford I et al. | The effects of treatment with alpha-lipoic acid or evening primrose oil on vascular hemostatic and lipid risk factors, blood flow, and peripheral nerve conduction in the streptozotocin-diabetic rat. | 2001 | Metab. Clin. Exp. | pmid:11474472 |
| Tsimaratos M et al. | Gamma-linolenic acid restores renal medullary thick ascending limb Na(+),K(+)-ATPase activity in diabetic rats. | 2001 | J. Nutr. | pmid:11739860 |
| Thies F et al. | Influence of dietary supplementation with long-chain n-3 or n-6 polyunsaturated fatty acids on blood inflammatory cell populations and functions and on plasma soluble adhesion molecules in healthy adults. | 2001 | Lipids | pmid:11795850 |
| Kaku S et al. | Interactions of dietary fats and proteins on fatty acid composition of immune cells and LTB4 production by peritoneal exudate cells of rats. | 2001 | Biosci. Biotechnol. Biochem. | pmid:11302164 |
| Sims EC and Plowman PN | Stereotactic radiosurgery XII. Large AVM and the failure of the radiation response modifier gamma linolenic acid to improve the therapeutic ratio. | 2001 | Br J Neurosurg | pmid:11303657 |
| Little C and Parsons T | Herbal therapy for treating rheumatoid arthritis. | 2001 | Cochrane Database Syst Rev | pmid:11279784 |
| Frenoux JM et al. | A polyunsaturated fatty acid diet lowers blood pressure and improves antioxidant status in spontaneously hypertensive rats. | 2001 | J. Nutr. | pmid:11208936 |