| MeSH term | MeSH ID | Detail |
|---|---|---|
| Stomach Ulcer | D013276 | 75 associated lipids |
| Hyperlipidemias | D006949 | 73 associated lipids |
| Melanoma | D008545 | 69 associated lipids |
| Neuroblastoma | D009447 | 66 associated lipids |
| Cystic Fibrosis | D003550 | 65 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Kidney Failure, Chronic | D007676 | 51 associated lipids |
| Osteosarcoma | D012516 | 50 associated lipids |
| Thrombosis | D013927 | 49 associated lipids |
gamma-Linolenic acid
Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.
Cross Reference
Introduction
To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid
PubChem Associated disorders and diseases
What pathways are associated with gamma-Linolenic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with gamma-Linolenic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with gamma-Linolenic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
What genes are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
What common seen animal models are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with gamma-Linolenic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Bordoni A et al. | Manipulation of lipid composition of rat heart myocytes aged in culture and its effect on alpha1-adrenoceptor stimulation. | 1997 | Biochim. Biophys. Acta | pmid:9366250 |
| Larsen LN et al. | Polyunsaturated thia- and oxa-fatty acids: incorporation into cell-lipids and their effects on arachidonic acid- and eicosanoid synthesis. | 1997 | Biochim. Biophys. Acta | pmid:9366251 |
| Ziboh VA et al. | gamma-Linolenic acid-containing diet attenuates bleomycin-induced lung fibrosis in hamsters. | 1997 | Lipids | pmid:9252965 |
| De La Cruz JP et al. | Effect of evening primrose oil on platelet aggregation in rabbits fed an atherogenic diet. | 1997 | Thromb. Res. | pmid:9253809 |
| Küpper C | [Premenstrual syndrome: does gamma-linolenic acid help?]. | 1997 | Fortschr. Med. | pmid:9173016 |
| Vassilopoulos D et al. | Gammalinolenic acid and dihomogammalinolenic acid suppress the CD3-mediated signal transduction pathway in human T cells. | 1997 | Clin. Immunol. Immunopathol. | pmid:9175912 |
| Manninen P and Laakso P | Capillary supercritical fluid chromatography--atmospheric pressure chemical ionization mass spectrometry of gamma- and alpha-linolenic acid containing triacylglycerols in berry oils. | 1997 | Lipids | pmid:9270973 |
| Fan YY et al. | Dietary gamma-linolenic acid enhances mouse macrophage-derived prostaglandin E1 which inhibits vascular smooth muscle cell proliferation. | 1997 | J. Nutr. | pmid:9278557 |
| Jiang WG et al. | Gamma linolenic acid regulates expression of maspin and the motility of cancer cells. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9299418 |
| Mancuso P et al. | Dietary fish oil and fish and borage oil suppress intrapulmonary proinflammatory eicosanoid biosynthesis and attenuate pulmonary neutrophil accumulation in endotoxic rats. | 1997 | Crit. Care Med. | pmid:9233748 |
| Johnson MM et al. | Dietary supplementation with gamma-linolenic acid alters fatty acid content and eicosanoid production in healthy humans. | 1997 | J. Nutr. | pmid:9237935 |
| Harbige LS et al. | Protective mechanisms by omega-6 lipids in experimental autoimmune encephalomyelitis (EAE) are associated with cytokines and eicosanoids. | 1997 | Biochem. Soc. Trans. | pmid:9191387 |
| Fisher BA and Harbige LS | Effect of omega-6 lipid-rich borage oil feeding on immune function in healthy volunteers. | 1997 | Biochem. Soc. Trans. | pmid:9191388 |
| Kokura S et al. | Efficacy of hyperthermia and polyunsaturated fatty acids on experimental carcinoma. | 1997 | Cancer Res. | pmid:9187121 |
| Magnusson G et al. | Plasma and tissue levels of lipids, fatty acids and plasma carnitine in neonates receiving a new fat emulsion. | 1997 | Acta Paediatr. | pmid:9202801 |
| Garland HO et al. | Dietary essential fatty acid supplementation, urinary calcium excretion and reproductive performance in the diabetic pregnant rat. | 1997 | J. Endocrinol. | pmid:9203989 |
| Murray MJ and Zhang T | The incorporation of dietary n-3 polyunsaturated fatty acids into porcine platelet phospholipids and their effects on platelet thromboxane A2 release. | 1997 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9089803 |
| Bard JM et al. | A therapeutic dosage (3 g/day) of borage oil supplementation has no effect on platelet aggregation in healthy volunteers. | 1997 | Fundam Clin Pharmacol | pmid:9107561 |
| Fang C et al. | Expression of constitutive cyclo-oxygenase (COX-1) in rats with streptozotocin-induced diabetes; effects of treatment with evening primrose oil or an aldose reductase inhibitor on COX-1 mRNA levels. | 1997 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9051726 |
| Liang T and Liao S | Growth suppression of hamster flank organs by topical application of gamma-linolenic and other fatty acid inhibitors of 5alpha-reductase. | 1997 | J. Invest. Dermatol. | pmid:9242500 |
| McGahon B et al. | The ability of aged rats to sustain long-term potentiation is restored when the age-related decrease in membrane arachidonic acid concentration is reversed. | 1997 | Neuroscience | pmid:9300396 |
| Rossetti RG et al. | Oral administration of unsaturated fatty acids: effects on human peripheral blood T lymphocyte proliferation. | 1997 | J. Leukoc. Biol. | pmid:9335312 |
| Horrobin DF | Essential fatty acids in the management of impaired nerve function in diabetes. | 1997 | Diabetes | pmid:9285506 |
| Quoc KP and Dubacq JP | Effect of growth temperature on the biosynthesis of eukaryotic lipid molecular species by the cyanobacterium Spirulina platensis. | 1997 | Biochim. Biophys. Acta | pmid:9219908 |
| Purasiri P et al. | Modulation in vitro of human natural cytotoxicity, lymphocyte proliferative response to mitogens and cytokine production by essential fatty acids. | 1997 | Immunology | pmid:9415022 |
| de Antueno R et al. | In vivo and in vitro biotransformation of the lithium salt of gamma-linolenic acid by three human carcinomas. | 1997 | Br. J. Cancer | pmid:9192987 |
| Mpanju O et al. | Selective cytotoxicity of lithium gamma-linolenic acid in human T cells chronically and productively infected with HIV. | 1997 | Antivir. Ther. (Lond.) | pmid:11322262 |
| Griffiths G et al. | Effect of n-6 polyunsaturated fatty acids on growth and lipid composition of neoplastic and non-neoplastic canine prostate epithelial cell cultures. | 1997 | Prostate | pmid:9108883 |
| Pohl CH et al. | The production of gamma-linolenic acid by selected members of the Dikaryomycota grown on different carbon sources. | 1997 | Antonie Van Leeuwenhoek | pmid:9403104 |
| Jiang WG et al. | Regulation of desmosomal cell adhesion in human tumour cells by polyunsaturated fatty acids. | 1997 | Clin. Exp. Metastasis | pmid:9344043 |
| Campbell EM et al. | Premenstrual symptoms in general practice patients. Prevalence and treatment. | 1997 | J Reprod Med | pmid:9350019 |
| Morris GM et al. | Modulation of the cell kinetics of pig skin by the topical application of evening primrose oil or Lioxasol. | 1997 Aug-Sep | Cell Prolif. | pmid:9501921 |
| Borrek S et al. | [Gamma-linolenic-acid-rich borage seed oil capsules in children with atopic dermatitis. A placebo-controlled double-blind study]. | 1997 May-Jun | Klin Padiatr | pmid:9244815 |
| Palombo JD et al. | Cyclic vs continuous enteral feeding with omega-3 and gamma-linolenic fatty acids: effects on modulation of phospholipid fatty acids in rat lung and liver immune cells. | 1997 May-Jun | JPEN J Parenter Enteral Nutr | pmid:9168366 |
| Tollesson A et al. | Malassezia furfur in infantile seborrheic dermatitis. | 1997 Nov-Dec | Pediatr Dermatol | pmid:9436835 |
| Kairemo KJ et al. | Effects of lithium gammalinolenate on the perfusion of liver and pancreatic tissues in pancreatic cancer. | 1997 Sep-Oct | Anticancer Res. | pmid:9427770 |
| Andreassi M et al. | Efficacy of gamma-linolenic acid in the treatment of patients with atopic dermatitis. | 1997 Sep-Oct | J. Int. Med. Res. | pmid:9364289 |
| Tanaka T et al. | Methylene-interrupted double bond in polyunsaturated fatty acid is an essential structure for metabolism by the fatty acid chain elongation system of rat liver. | 1998 | Biochim. Biophys. Acta | pmid:9748638 |
| de Vries JE | [Painful breasts]. | 1998 | Ned Tijdschr Geneeskd | pmid:9749309 |
| Johnson SR | Premenstrual syndrome therapy. | 1998 | Clin Obstet Gynecol | pmid:9646973 |
| Engler MM et al. | Effects of dietary gamma-linolenic acid on blood pressure and adrenal angiotensin receptors in hypertensive rats. | 1998 | Proc. Soc. Exp. Biol. Med. | pmid:9648942 |
| Giamarellos-Bourboulis EJ et al. | In vitro activity of polyunsaturated fatty acids on Pseudomonas aeruginosa: relationship to lipid peroxidation. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9654401 |
| Kahler CP and Du Plooy WJ | Effect of gammalinolenic acid, dihomogammalinolenic acid, ascorbyl-6-gammalinolenic acid, and ascorbyl-6-dihomo gammalinolenic acid on histamine- and methacholine-induced contraction of the isolated guinea pig tracheal chain. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9654407 |
| Solomon LZ et al. | Bladder cancer recurrence by implantation of exfoliated cells: is gamma-linolenic acid an effective tumoricidal agent? | 1998 | Br J Urol | pmid:9698674 |
| Vartak S et al. | Gamma-linolenic acid (GLA) is cytotoxic to 36B10 malignant rat astrocytoma cells but not to 'normal' rat astrocytes. | 1998 | Br. J. Cancer | pmid:9635836 |
| Ramesh G and Das UN | Effect of evening primrose and fish oils on two stage skin carcinogenesis in mice. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9844986 |
| Kuruvilla R et al. | Evening primrose oil treatment corrects reduced conduction velocity but not depletion of arachidonic acid in nerve from streptozotocin-induced diabetic rats. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9844993 |
| Schellhammer PF | Intravesical chemotherapy with gamma linolenic acid becomes a reality. | 1998 | J. Urol. | pmid:9817299 |
| Solomon LZ et al. | Intravesical chemotherapy with gamma linolenic acid becomes a realistic prospect in serum-free applications: in vitro cytotoxicity and systemic absorption studies. | 1998 | J. Urol. | pmid:9817384 |
| Marra F et al. | Effects of supplementation with unsaturated fatty acids on plasma and membrane lipid composition and platelet function in patients with cirrhosis and defective aggregation. | 1998 | J. Hepatol. | pmid:9566835 |