| MeSH term | MeSH ID | Detail |
|---|---|---|
| Stomach Ulcer | D013276 | 75 associated lipids |
| Hyperlipidemias | D006949 | 73 associated lipids |
| Melanoma | D008545 | 69 associated lipids |
| Neuroblastoma | D009447 | 66 associated lipids |
| Cystic Fibrosis | D003550 | 65 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Kidney Failure, Chronic | D007676 | 51 associated lipids |
| Osteosarcoma | D012516 | 50 associated lipids |
| Thrombosis | D013927 | 49 associated lipids |
gamma-Linolenic acid
Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.
Cross Reference
Introduction
To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid
PubChem Associated disorders and diseases
What pathways are associated with gamma-Linolenic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with gamma-Linolenic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with gamma-Linolenic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
What genes are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
What common seen animal models are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with gamma-Linolenic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Pakala R et al. | Eicosapentaenoic acid and docosahexaenoic acid selectively attenuate U46619-induced smooth muscle cell proliferation. | 1999 | Lipids | pmid:10574655 |
| Ward GR et al. | Effects of gamma-linolenic acid and docosahexaenoic acid in formulae on brain fatty acid composition in artificially reared rats. | 1999 | Lipids | pmid:10580333 |
| Joubert AM et al. | Comparative study of the effects of polyunsaturated fatty acids and their metabolites on cell growth and tyrosine kinase activity in oesophageal carcinoma cells. | 1999 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10582657 |
| Bell HS et al. | Effects of N-6 essential fatty acids on glioma invasion and growth: experimental studies with glioma spheroids in collagen gels. | 1999 | J. Neurosurg. | pmid:10584845 |
| Srinivas CV et al. | Safflower petals: a source of gamma linolenic acid. | 1999 | Plant Foods Hum Nutr | pmid:10646633 |
| Hornych A et al. | Effect of gamma-linolenic acid on plasma and membrane lipids and renal prostaglandins in old subjects. | 1999 | Br J Clin Pharmacol | pmid:10651470 |
| Fan YY et al. | Modulation of atherogenesis by dietary gamma-linolenic acid. | 1999 | Adv. Exp. Med. Biol. | pmid:10667372 |
| Vartak S et al. | The selective cytotoxicity of gamma-linolenic acid (GLA) is associated with increased oxidative stress. | 1999 | Adv. Exp. Med. Biol. | pmid:10667373 |
| Robbins M et al. | gamma-linolenic acid (GLA)-mediated cytotoxicity in human prostate cancer cells. | 1999 | Adv. Exp. Med. Biol. | pmid:10667374 |
| Harris JE et al. | Five-lipoxygenase inhibitors reduce Panc-1 survival: synergism of MK886 with gamma linolenic acid. | 1999 | Adv. Exp. Med. Biol. | pmid:10667375 |
| Ramrath S et al. | Stimulation of cardiac glucose transport by thioctic acid and insulin. | 1999 | Horm. Metab. Res. | pmid:10668913 |
| Motaung E et al. | Cytotoxicity of combined essential fatty acids on a human prostate cancer cell line. | 1999 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10670696 |
| Davies CL et al. | Effect of gamma-linolenic acid on cellular uptake of structurally related anthracyclines in human drug sensitive and multidrug resistant bladder and breast cancer cell lines. | 1999 | Eur. J. Cancer | pmid:10673983 |
| Woltil HA et al. | Does supplementation of formula with evening primrose and fish oils augment long chain polyunsaturated fatty acid status of low birthweight infants to that of breast-fed counterparts? | 1999 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10359022 |
| DeLuca P et al. | Effects of gammalinolenic acid on interleukin-1 beta and tumor necrosis factor-alpha secretion by stimulated human peripheral blood monocytes: studies in vitro and in vivo. | 1999 | J. Investig. Med. | pmid:10361385 |
| Ilc K et al. | Cytotoxic effects of two gamma linoleic salts (lithium gammalinolenate or meglumine gammalinolenate) alone or associated with a nitrosourea: an experimental study on human glioblastoma cell lines. | 1999 | Anticancer Drugs | pmid:10378677 |
| Tsevegsüren N et al. | Occurrence of gamma-linolenic acid in compositae: a study of Youngia tenuicaulis seed oil. | 1999 | Lipids | pmid:10380126 |
| Wolf LA and Laster SM | Characterization of arachidonic acid-induced apoptosis. | 1999 | Cell Biochem. Biophys. | pmid:10403056 |
| Cai J et al. | Inhibition of the expression of VE-cadherin/catenin complex by gamma linolenic acid in human vascular endothelial cells, and its impact on angiogenesis. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10222244 |
| Leaver HA et al. | Dynamics of reactive oxygen intermediate production in human glioma: n-6 essential fatty acid effects. | 1999 | Eur. J. Clin. Invest. | pmid:10202379 |
| Passorn S et al. | Heterologous expression of Mucor rouxii delta(12)-desaturase gene in Saccharomyces cerevisiae. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10486251 |
| Patel J and Tomlinson DR | Nerve conduction impairment in experimental diabetes-proximodistal gradient of severity. | 1999 | Muscle Nerve | pmid:10487907 |
| Palombo JD et al. | Effect of short-term enteral feeding with eicosapentaenoic and gamma-linolenic acids on alveolar macrophage eicosanoid synthesis and bactericidal function in rats. | 1999 | Crit. Care Med. | pmid:10507617 |
| Senanayake SP and Shahidi F | Enzyme-assisted acidolysis of borage (Borago officinalis L.) and evening primrose (Oenothera biennis L.) oils: incorporation of omega-3 polyunsaturated fatty acids. | 1999 | J. Agric. Food Chem. | pmid:10552616 |
| Gehring W et al. | Effect of topically applied evening primrose oil on epidermal barrier function in atopic dermatitis as a function of vehicle. | 1999 | Arzneimittelforschung | pmid:10442214 |
| Cheung KL | Management of cyclical mastalgia in oriental women: pioneer experience of using gamolenic acid (Efamast) in Asia. | 1999 | Aust N Z J Surg | pmid:10442919 |
| De La Cruz JP et al. | Antioxidant potential of evening primrose oil administration in hyperlipemic rabbits. | 1999 | Life Sci. | pmid:10462081 |
| Schwartz Z et al. | Arachidonic acid directly mediates the rapid effects of 24,25-dihydroxyvitamin D3 via protein kinase C and indirectly through prostaglandin production in resting zone chondrocytes. | 1999 | Endocrinology | pmid:10385391 |
| Henz BM et al. | Double-blind, multicentre analysis of the efficacy of borage oil in patients with atopic eczema. | 1999 | Br. J. Dermatol. | pmid:10233322 |
| Likhodii SS and Cunnane SC | Uptake of 13C-tracer arachidonate and gamma-linolenate by the brain and liver of the suckling rat observed using 13C-NMR. | 1999 | J. Neurochem. | pmid:10349866 |
| Yoshimoto-Furuie K et al. | Effects of oral supplementation with evening primrose oil for six weeks on plasma essential fatty acids and uremic skin symptoms in hemodialysis patients. | 1999 | Nephron | pmid:9933750 |
| Murakami K et al. | Evidence for direct binding of fatty acids and eicosanoids to human peroxisome proliferators-activated receptor alpha. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10403814 |
| Pirich C et al. | Effects of fish oil supplementation on platelet survival and ex vivo platelet function in hypercholesterolemic patients. | 1999 | Thromb. Res. | pmid:10588465 |
| Redden PR et al. | Acyloxymethyl acidic drug derivatives: in vitro hydrolytic reactivity. | 1999 | Int J Pharm | pmid:10370185 |
| Dove D and Johnson P | Oral evening primrose oil: its effect on length of pregnancy and selected intrapartum outcomes in low-risk nulliparous women. | 1999 May-Jun | J Nurse Midwifery | pmid:10380450 |
| De Antueno R et al. | Tissue distribution and metabolism of gamma-linolenoyl-3-eicosapentaenoyl propane diol enterally or intravenously administered to mice bearing human pancreatic carcinomas. | 1999 May-Jun | Anticancer Res. | pmid:10470146 |
| Zurier RB et al. | Human peripheral blood T lymphocyte proliferation after activation of the T cell receptor: effects of unsaturated fatty acids. | 1999 May-Jun | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10471124 |
| Palombo JD et al. | Comparison of growth and fatty acid metabolism in rats fed diets containing equal levels of gamma-linolenic acid from high gamma-linolenic acid canola oil or borage oil. | 2000 | Lipids | pmid:11026618 |
| Fokkema MR et al. | Short-term supplementation of low-dose gamma-linolenic acid (GLA), alpha-linolenic acid (ALA), or GLA plus ALA does not augment LCP omega 3 status of Dutch vegans to an appreciable extent. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11090255 |
| Worm M and Henz BM | Novel unconventional therapeutic approaches to atopic eczema. | 2000 | Dermatology (Basel) | pmid:11096188 |
| Harbige LS et al. | The protective effects of omega-6 fatty acids in experimental autoimmune encephalomyelitis (EAE) in relation to transforming growth factor-beta 1 (TGF-beta1) up-regulation and increased prostaglandin E2 (PGE2) production. | 2000 | Clin. Exp. Immunol. | pmid:11122253 |
| Horner NK and Lampe JW | Potential mechanisms of diet therapy for fibrocystic breast conditions show inadequate evidence of effectiveness. | 2000 | J Am Diet Assoc | pmid:11103660 |
| Pakala R et al. | Vascular smooth muscle cells preloaded with eicosapentaenoic acid and docosahexaenoic acid fail to respond to serotonin stimulation. | 2000 | Atherosclerosis | pmid:11058699 |
| Vinik AI et al. | Diabetic neuropathies. | 2000 | Diabetologia | pmid:10990072 |
| Guil-Guerrero JL et al. | Occurrence and characterization of oils rich in gamma-linolenic acid Part I: Echium seeds from Macaronesia. | 2000 | Phytochemistry | pmid:10731022 |
| Hindo J et al. | Evidence of the formation of different hydroperoxides in irradiated gamma-linolenate solutions: effect of micelle formation. | 2000 | Radiat. Res. | pmid:10629620 |
| Beaudoin F et al. | Production of C20 polyunsaturated fatty acids (PUFAs) by pathway engineering: identification of a PUFA elongase component from Caenorhabditis elegans. | 2000 | Biochem. Soc. Trans. | pmid:11171161 |
| Shahidi F | Antioxidant factors in plant foods and selected oilseeds. | 2000 | Biofactors | pmid:11237180 |
| Horrobin DF | Essential fatty acid metabolism and its modification in atopic eczema. | 2000 | Am. J. Clin. Nutr. | pmid:10617999 |
| Petrik MB et al. | Highly unsaturated (n-3) fatty acids, but not alpha-linolenic, conjugated linoleic or gamma-linolenic acids, reduce tumorigenesis in Apc(Min/+) mice. | 2000 | J. Nutr. | pmid:11015469 |