| MeSH term | MeSH ID | Detail |
|---|---|---|
| Osteosarcoma | D012516 | 50 associated lipids |
| Salivary Gland Diseases | D012466 | 1 associated lipids |
| Respiratory Insufficiency | D012131 | 10 associated lipids |
| Respiratory Distress Syndrome, Adult | D012128 | 15 associated lipids |
| Raynaud Disease | D011928 | 7 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Premenstrual Syndrome | D011293 | 7 associated lipids |
| Pityriasis | D010915 | 3 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
gamma-Linolenic acid
Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.
Cross Reference
Introduction
To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid
PubChem Associated disorders and diseases
What pathways are associated with gamma-Linolenic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with gamma-Linolenic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with gamma-Linolenic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
What genes are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
What common seen animal models are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with gamma-Linolenic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Larsson-Backström C et al. | Effects of dietary alpha- and gamma-linolenic acids on liver fatty acids, lipid metabolism, and survival in sepsis. | 1995 | Shock | pmid:7552772 |
| Li MC et al. | [Expression of delta6-fatty acid desaturase gene from Mortierella alpina in Pichia pastoris]. | 2004 | Sheng Wu Gong Cheng Xue Bao | pmid:16108486 |
| Zhang Q et al. | [Progress on molecular biology of delta6-fatty acid desaturases]. | 2004 | Sheng Wu Gong Cheng Xue Bao | pmid:15971598 |
| Li MC et al. | [Expression of Mortierella isabellina delta6-fatty acid desaturase gene in gamma-linolenic acid production in transgenic tobacco]. | 2003 | Sheng Wu Gong Cheng Xue Bao | pmid:15966318 |
| Rothman D et al. | Botanical lipids: effects on inflammation, immune responses, and rheumatoid arthritis. | 1995 | Semin. Arthritis Rheum. | pmid:8578315 |
| Saad N et al. | Optimization of aeration and agitation rate for lipid and gamma linolenic acid production by Cunninghamella bainieri 2A1 in submerged fermentation using response surface methodology. | 2014 | ScientificWorldJournal | pmid:25610901 |
| Simmons DA et al. | Significance of tissue myo-inositol concentrations in metabolic regulation in nerve. | 1982 | Science | pmid:6285474 |
| Manthorpe R and Prause JU | Treatment of Sjögren's syndrome: an overview. | 1986 | Scand. J. Rheumatol. Suppl. | pmid:3296150 |
| Horrobin DF | Essential fatty acid and prostaglandin metabolism in Sjögren's syndrome, systemic sclerosis and rheumatoid arthritis. | 1986 | Scand. J. Rheumatol. Suppl. | pmid:3296151 |
| Hansen TM et al. | Treatment of rheumatoid arthritis with prostaglandin E1 precursors cis-linoleic acid and gamma-linolenic acid. | 1983 | Scand. J. Rheumatol. | pmid:6304871 |
| Theander E et al. | Gammalinolenic acid treatment of fatigue associated with primary Sjögren's syndrome. | 2002 | Scand. J. Rheumatol. | pmid:12109650 |
| Oxholm P et al. | Patients with primary Sjögren's syndrome treated for two months with evening primrose oil. | 1986 | Scand. J. Rheumatol. | pmid:3529370 |
| de Kock M et al. | Effects of gamma-linolenic acid on mitosis and nuclear morphology in osteogenic sarcoma cells. | 1992 | S. Afr. Med. J. | pmid:1315459 |
| Leary WP et al. | Some effects of gamma-linolenic acid on cultured human oesophageal carcinoma cells. | 1982 | S. Afr. Med. J. | pmid:6291175 |
| Dippenaar N et al. | The reversibility of cancer: evidence that malignancy in human hepatoma cells is gamma-linolenic acid deficiency-dependent. | 1982 | S. Afr. Med. J. | pmid:6291176 |
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| Botha JH et al. | Parenteral gamma-linolenic acid administration in nude mice bearing a range of human tumour xenografts. | 1983 | S. Afr. Med. J. | pmid:6304925 |
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| van der Merwe CF | The reversibility of cancer. | 1984 | S. Afr. Med. J. | pmid:6326340 |
| Oakley OR et al. | The effects of lithium gamma-linolenic acid in reversing LPBM5 MuLV induced suppression of hematopoietic progenitor cells in vitro. | 1998 Jan-Jun | Rom J Physiol | pmid:11000861 |
| Szczesna M | [Therapeutic assessment of the evening primrose]. | 1993 | Rocz Panstw Zakl Hig | pmid:8016534 |
| Macfarlane GJ et al. | Evidence for the efficacy of complementary and alternative medicines in the management of rheumatoid arthritis: a systematic review. | 2011 | Rheumatology (Oxford) | pmid:21652584 |
| Soeken KL et al. | Herbal medicines for the treatment of rheumatoid arthritis: a systematic review. | 2003 | Rheumatology (Oxford) | pmid:12709541 |
| Manthorpe R et al. | Primary Sjögren's syndrome treated with Efamol/Efavit. A double-blind cross-over investigation. | 1984 | Rheumatol. Int. | pmid:6385206 |
| Webb J and McCredie M | Primary Sjögren's syndrome treated with Efamol/efavit. A double-blind cross-over investigation. | 1985 | Rheumatol. Int. | pmid:4048763 |
| Willemaers V et al. | [Atopic dermatitis]. | 1998 | Rev Med Liege | pmid:9564223 |
| DeMichele SJ et al. | A nutritional strategy to improve oxygenation and decrease morbidity in patients who have acute respiratory distress syndrome. | 2006 | Respir Care Clin N Am | pmid:17150431 |
| Castellanos P et al. | Changes in fatty acid profiles in testis and spermatozoa of red deer exposed to metal pollution. | 2010 | Reprod. Toxicol. | pmid:20096347 |
| Hindo J et al. | Evidence of the formation of different hydroperoxides in irradiated gamma-linolenate solutions: effect of micelle formation. | 2000 | Radiat. Res. | pmid:10629620 |
| Vaddadi KS et al. | A double-blind trial of essential fatty acid supplementation in patients with tardive dyskinesia. | 1989 | Psychiatry Res | pmid:2565585 |
| Dobryniewski J et al. | [The gamma-linolenic acid (GLA)--the therapeutic value]. | 2007 | Prz. Lek. | pmid:17892041 |
| Griffiths G et al. | Effect of n-6 polyunsaturated fatty acids on growth and lipid composition of neoplastic and non-neoplastic canine prostate epithelial cell cultures. | 1997 | Prostate | pmid:9108883 |
| Papanikolaou N et al. | Effects of OKY-046 and nifedipine in cyclosporine-induced renal dysfunction in rats. | 1996 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8951993 |
| Mengeaud V et al. | Effects of eicosapentaenoic acid, gamma-linolenic acid and prostaglandin E1 on three human colon carcinoma cell lines. | 1992 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:1337209 |
| de Kock M et al. | The induction of apoptosis in human cervical carcinoma (HeLa) cells by gamma-linolenic acid. | 1996 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9014218 |
| Miller MA and Morgan RJ | Eicosanoids, erections and erectile dysfunction. | 1994 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:7938091 |
| Singer P et al. | N-6 and N-3 PUFA in liver lipids, thromboxane formation and blood pressure from SHR during diets supplemented with evening primrose, sunflowerseed or fish oil. | 1990 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:2336450 |
| Hrelia S et al. | Concentration- and time-dependent effects of gamma-linolenic acid supplementation to tumor cells in culture. | 1999 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10397404 |
| Pakala R et al. | Thromboxane A2 fails to induce proliferation of smooth muscle cells enriched with eicosapentaenoic acid and docosahexaenoic acid. | 1999 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10397410 |
| Kavanagh K et al. | Stearidonic and γ-linolenic acids in echium oil improves glucose disposal in insulin resistant monkeys. | 2013 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:23664597 |
| Leaver HA et al. | Intracellular oxidation by human glioma cell populations: effect of arachidonic acid. | 2004 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:15062847 |
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| Haag M et al. | Polyunsaturated fatty acids inhibit Mg2+ -ATPase in basolateral membranes from rat enterocytes. | 1999 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10477038 |
| Zurier RB et al. | Human peripheral blood T lymphocyte proliferation after activation of the T cell receptor: effects of unsaturated fatty acids. | 1999 May-Jun | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10471124 |
| Bell JG et al. | Diets rich in eicosapentaenoic acid and gamma-linolenic acid affect phospholipid fatty acid composition and production of prostaglandins E1, E2 and E3 in turbot (Scophthalmus maximus), a species deficient in delta 5 fatty acid desaturase. | 1995 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8577782 |
| Agostoni C et al. | Biochemical effects of supplemented long-chain polyunsaturated fatty acids in hyperphenylalaninemia. | 2001 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11237478 |
| Hrelia S et al. | Role of gamma-linolenic acid in counteracting doxorubicin-induced damage in cultured rat cardiomyocytes. | 2001 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11334548 |
| Leaver HA et al. | Antitumour and pro-apoptotic actions of highly unsaturated fatty acids in glioma. | 2002 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12051954 |
| Watkins G et al. | Gamma-Linolenic acid regulates the expression and secretion of SPARC in human cancer cells. | 2005 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:15763439 |