gamma-Linolenic acid

Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.

Cross Reference

Introduction

To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid

MeSH term MeSH ID Detail
Carcinoma 256, Walker D002279 22 associated lipids
Neoplasm Invasiveness D009361 23 associated lipids
Neoplasms, Hormone-Dependent D009376 23 associated lipids
Cardiovascular Diseases D002318 24 associated lipids
Encephalomyelitis, Autoimmune, Experimental D004681 26 associated lipids
Gastritis D005756 27 associated lipids
Alcoholism D000437 27 associated lipids
Dermatitis D003872 30 associated lipids
Acute Lung Injury D055371 33 associated lipids
Hyperplasia D006965 34 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Leukemia P388 D007941 43 associated lipids
Psoriasis D011565 47 associated lipids
Thrombosis D013927 49 associated lipids
Osteosarcoma D012516 50 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Pain D010146 64 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with gamma-Linolenic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with gamma-Linolenic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with gamma-Linolenic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with gamma-Linolenic acid

Download all related citations
Per page 10 20 50 100 | Total 1121
Authors Title Published Journal PubMed Link
Delmonte P et al. Synthesis and isolation of trans-7,cis-9 octadecadienoic acid and other CLA isomers by base conjugation of partially hydrogenated gamma-linolenic acid. 2003 Lipids pmid:12880116
Dobbin SN Evening primrose oil and epilepsy. 1992 Dec 19-26 Vet. Rec. pmid:1287960
Giamarellos-Bourboulis EJ et al. Lipid peroxidation by Pseudomonas aeruginosa in the pathogenesis of nosocomial sepsis. 2003 Jan-Mar J Postgrad Med pmid:12865564
McFayden IJ et al. Cyclical breast pain--some observations and the difficulties in treatment. 1992 Br J Clin Pract pmid:1286012
Surette ME et al. Inhibition of leukotriene biosynthesis by a novel dietary fatty acid formulation in patients with atopic asthma: a randomized, placebo-controlled, parallel-group, prospective trial. 2003 Clin Ther pmid:12852711
Surette ME et al. Inhibition of leukotriene synthesis, pharmacokinetics, and tolerability of a novel dietary fatty acid formulation in healthy adult subjects. 2003 Clin Ther pmid:12852710
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Macrì A et al. Effect of linoleic acid and gamma-linolenic acid on tear production, tear clearance and on the ocular surface after photorefractive keratectomy. 2003 Graefes Arch. Clin. Exp. Ophthalmol. pmid:12768289
Wainwright PE et al. Effects of high-gamma-linolenic acid canola oil compared with borage oil on reproduction, growth, and brain and behavioral development in mice. 2003 Lipids pmid:12733750
Spector SL and Surette ME Diet and asthma: has the role of dietary lipids been overlooked in the management of asthma? 2003 Ann. Allergy Asthma Immunol. pmid:12722956
Soeken KL et al. Herbal medicines for the treatment of rheumatoid arthritis: a systematic review. 2003 Rheumatology (Oxford) pmid:12709541
Jelińska M et al. Effects of dietary linseed, evening primrose or fish oils on fatty acid and prostaglandin E2 contents in the rat livers and 7,12-dimethylbenz[a]anthracene-induced tumours. 2003 Biochim. Biophys. Acta pmid:12697300
Seibel MM Treating hot flushes without hormone replacement therapy. 2003 J Fam Pract pmid:12681090
Vecera R et al. Antioxidant status, lipoprotein profile and liver lipids in rats fed on high-cholesterol diet containing currant oil rich in n-3 and n-6 polyunsaturated fatty acids. 2003 Physiol Res pmid:12678660
Nelson JL et al. Effect of enteral feeding with eicosapentaenoic acid, gamma-linolenic acid, and antioxidants on antioxidant status in patients with acute respiratory distress syndrome. 2003 Mar-Apr JPEN J Parenter Enteral Nutr pmid:12665164
Whelan J et al. Dietary EPA reduces tumor load in ApcMin/+ mice by altering arachidonic acid metabolism, but conjugated linoleic acid, gamma--and alpha-linolenic acids have no effect. 2002 Adv. Exp. Med. Biol. pmid:12664643
van Gool CJ et al. Gamma-linolenic acid supplementation for prophylaxis of atopic dermatitis--a randomized controlled trial in infants at high familial risk. 2003 Am. J. Clin. Nutr. pmid:12663296
Shimizu S and Nakano M Structural characterization of triacylglycerol in several oils containing gamma-linolenic acid. 2003 Biosci. Biotechnol. Biochem. pmid:12619674
Hirano A et al. Arachidonic acid-induced channel- and carrier-type ion transport across planar bilayer lipid membranes. 2003 Anal Sci pmid:12608744
Barabino S et al. Systemic linoleic and gamma-linolenic acid therapy in dry eye syndrome with an inflammatory component. 2003 Cornea pmid:12605039
Usami M et al. Effect of gamma-linolenic acid or docosahexaenoic acid on tight junction permeability in intestinal monolayer cells and their mechanism by protein kinase C activation and/or eicosanoid formation. 2003 Nutrition pmid:12591548
Rosenstein ED et al. Pilot study of dietary fatty acid supplementation in the treatment of adult periodontitis. 2003 Prostaglandins Leukot. Essent. Fatty Acids pmid:12591005
Pham H and Ziboh VA 5 alpha-reductase-catalyzed conversion of testosterone to dihydrotestosterone is increased in prostatic adenocarcinoma cells: suppression by 15-lipoxygenase metabolites of gamma-linolenic and eicosapentaenoic acids. 2002 J. Steroid Biochem. Mol. Biol. pmid:12589947
Halat KM and Dennehy CE Botanicals and dietary supplements in diabetic peripheral neuropathy. 2003 Jan-Feb J Am Board Fam Pract pmid:12583650
Xian M et al. Production of gamma-linolenic acid by disrupted mycelia of Mortierella isabellina. 2003 Lett. Appl. Microbiol. pmid:12581380
Pacht ER et al. Enteral nutrition with eicosapentaenoic acid, gamma-linolenic acid, and antioxidants reduces alveolar inflammatory mediators and protein influx in patients with acute respiratory distress syndrome. 2003 Crit. Care Med. pmid:12576957
Gimeno RE et al. Characterization of a heart-specific fatty acid transport protein. 2003 J. Biol. Chem. pmid:12556534
Duttaroy AK et al. Acyl-CoA thioesterase activity in human placental choriocarcinoma (BeWo), cells: effects of fatty acids. 2003 Prostaglandins Leukot. Essent. Fatty Acids pmid:12538089
Shotton HR et al. The effectiveness of treatments of diabetic autonomic neuropathy is not the same in autonomic nerves supplying different organs. 2003 Diabetes pmid:12502507
Harris NM et al. Epirubicin and meglumine gamma-linolenic acid: a logical choice of combination therapy for patients with superficial bladder carcinoma. 2003 Cancer pmid:12491507
Samuels R et al. Hypocholesterolemic effect of spirulina in patients with hyperlipidemic nephrotic syndrome. 2002 J Med Food pmid:12487756
Simoncíkova P et al. Comparison of the extrapancreatic action of gamma-linolenic acid and n-3 PUFAs in the high fat diet-induced insulin resistance [corrected]. 2002 Endocr Regul pmid:12466014
Funtikova NS et al. [Synthesis of biologically active lipids by fungus Mucor lusitanicus 306D grown on media with various composition]. 2002 Nov-Dec Prikl. Biokhim. Mikrobiol. pmid:12449793
Pham H et al. Activation of peroxisome proliferator-activated receptor (PPAR)-gamma by 15S-hydroxyeicosatrienoic acid parallels growth suppression of androgen-dependent prostatic adenocarcinoma cells. 2003 Cancer Lett. pmid:12445673
Leaver HA et al. Highly unsaturated fatty acid induced tumour regression in glioma pharmacodynamics and bioavailability of gamma linolenic acid in an implantation glioma model: effects on tumour biomass, apoptosis and neuronal tissue histology. 2002 Prostaglandins Leukot. Essent. Fatty Acids pmid:12445487
Blommers J et al. Evening primrose oil and fish oil for severe chronic mastalgia: a randomized, double-blind, controlled trial. 2002 Am. J. Obstet. Gynecol. pmid:12439536
Uesaka Y [Prevention and treatment of diabetic neuropathy]. 2002 Nippon Rinsho pmid:12430238
Ernst E Ayurvedic medicines. 2002 Pharmacoepidemiol Drug Saf pmid:12426929
Berry JA Benign breast pain. New approaches manage this common condition more effectively. 2001 Adv Nurse Pract pmid:12400335
Pérez Y et al. Measurement by nuclear magnetic resonance diffusion of the dimensions of the mobile lipid compartment in C6 cells. 2002 Cancer Res. pmid:12384523
Gillis RC et al. Eicosapentaenoic acid and gamma-linolenic acid induce apoptosis in HL-60 cells. 2002 J. Surg. Res. pmid:12384078
Turon F et al. A direct method for regiospecific analysis of TAG using alpha-MAG. 2002 Lipids pmid:12371754
Senanayake SP and Shahidi F Positional distribution of FA in TAG of enzymatically modified borage and evening primrose oils. 2002 Lipids pmid:12371752
Chung S et al. Gamma-linolenic acid in borage oil reverses epidermal hyperproliferation in guinea pigs. 2002 J. Nutr. pmid:12368400
Das UN Abrupt and complete occlusion of tumor-feeding vessels by gamma-linolenic acid. 2002 Nutrition pmid:12297217
Dyer O Doctor accused of giving false information to drug trial. 2002 BMJ pmid:12269314
Hamburger M et al. Constituents in evening primrose oil with radical scavenging, cyclooxygenase, and neutrophil elastase inhibitory activities. 2002 J. Agric. Food Chem. pmid:12236675
Khunyoshyeng S et al. Differential expression of desaturases and changes in fatty acid composition during sporangiospore germination and development in Mucor rouxii. 2002 Fungal Genet. Biol. pmid:12223185
Hornych A et al. The effect of gamma-linolenic acid on plasma and membrane lipids and renal prostaglandin synthesis in older subjects. 2002 Bratisl Lek Listy pmid:12190041
Jack AM et al. Effects of diabetes and evening primrose oil treatment on responses of aorta, corpus cavernosum and mesenteric vasculature in rats. 2002 Life Sci. pmid:12175702