Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.
To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Del Castillo ML et al. | Fatty acid content and juice characteristics in black currant (Ribes nigrum L.) genotypes. | 2004 | J. Agric. Food Chem. | pmid:14969555 |
Knorr R and Hamburger M | Quantitative analysis of anti-inflammatory and radical scavenging triterpenoid esters in evening primrose oil. | 2004 | J. Agric. Food Chem. | pmid:15161190 |
Liu JW et al. | Effect of long-term dietary supplementation of high-gamma-linolenic canola oil versus borage oil on growth, hematology, serum biochemistry, and N-6 fatty acid metabolism in rats. | 2004 | J. Agric. Food Chem. | pmid:15186123 |
Senanayake SP and Shahidi F | Enzyme-assisted acidolysis of borage (Borago officinalis L.) and evening primrose (Oenothera biennis L.) oils: incorporation of omega-3 polyunsaturated fatty acids. | 1999 | J. Agric. Food Chem. | pmid:10552616 |
Goffman FD and Galletti S | Gamma-linolenic acid and tocopherol contents in the seed oil of 47 accessions from several Ribes species. | 2001 | J. Agric. Food Chem. | pmid:11170598 |
Birch AE et al. | Antioxidant properties of evening primrose seed extracts. | 2001 | J. Agric. Food Chem. | pmid:11559161 |
Senanayake SP and Shahidi F | Structured lipids via lipase-catalyzed incorporation of eicosapentaenoic acid into borage (Borago officinalis L.) and evening primrose (Oenothera biennis L.) oils. | 2002 | J. Agric. Food Chem. | pmid:11804516 |
Teichert SA and Akoh CC | Modifications of stearidonic acid soybean oil by enzymatic acidolysis for the production of human milk fat analogues. | 2011 | J. Agric. Food Chem. | pmid:22097918 |
Hamburger M et al. | Constituents in evening primrose oil with radical scavenging, cyclooxygenase, and neutrophil elastase inhibitory activities. | 2002 | J. Agric. Food Chem. | pmid:12236675 |
Skogh M | Atopic eczema unresponsive to evening primrose oil (linoleic and gamma-linolenic acids) | 1986 | J. Am. Acad. Dermatol. | pmid:3013957 |
Melnik B and Plewig G | Atopic dermatitis and disturbances of essential fatty acid and prostaglandin E metabolism. | 1991 | J. Am. Acad. Dermatol. | pmid:1666398 |
Melnik BC and Plewig G | Is the origin of atopy linked to deficient conversion of omega-6-fatty acids to prostaglandin E1? | 1989 | J. Am. Acad. Dermatol. | pmid:2550526 |
Hanifin JM | Diet, nutrition, and allergy in atopic dermatitis. | 1983 | J. Am. Acad. Dermatol. | pmid:6863636 |
Guenther L and Wexler D | Efamol in the treatment of atopic dermatitis. | 1987 | J. Am. Acad. Dermatol. | pmid:3680673 |
Bamford JT et al. | Atopic eczema unresponsive to evening primrose oil (linoleic and gamma-linolenic acids). | 1985 | J. Am. Acad. Dermatol. | pmid:3908514 |
Ingram AJ et al. | Dietary alteration of dihomogamma-linolenic acid/arachidonic acid ratio in a rat 5/6-renal-ablation model. The Nutrition & Kidney Disease Research Group. | 1996 | J. Am. Soc. Nephrol. | pmid:8829117 |
Giamarellos-Bourboulis EJ et al. | In-vitro inhibitory activity of gamma-linolenic acid on Escherichia coli strains and its influence on their susceptibilities to various antimicrobial agents. | 1995 | J. Antimicrob. Chemother. | pmid:8522462 |
Papanikolaou S et al. | Repression of reserve lipid turnover in Cunninghamella echinulata and Mortierella isabellina cultivated in multiple-limited media. | 2004 | J. Appl. Microbiol. | pmid:15357737 |
Zikou E et al. | Evaluating glucose and xylose as cosubstrates for lipid accumulation and γ-linolenic acid biosynthesis of Thamnidium elegans. | 2013 | J. Appl. Microbiol. | pmid:23279437 |
Laho T et al. | Effects of prefermented cereal-derived substrates (ground barley and rye bran) enriched with fungal γ-linolenic acid on rumen fermentation parameters and lipid metabolism in vitro. | 2011 | J. Appl. Microbiol. | pmid:21672096 |
Wencelová M et al. | Substrates enriched by the fungus Cunninghamella echinulata: an in vitro study of nutrient composition, sheep rumen fermentation and lipid metabolism. | 2014 | J. Appl. Microbiol. | pmid:24995934 |
Kishino S et al. | Microbial production of conjugated gamma-linolenic acid from gamma-linolenic acid by Lactobacillus plantarum AKU 1009a. | 2010 | J. Appl. Microbiol. | pmid:19919619 |
Zhu Y and Zhang BB | Molecular cloning and functional characterization of a Δ6-fatty acid desaturase gene from Rhizopus oryzae. | 2013 | J. Basic Microbiol. | pmid:22961300 |
Muriana FJ et al. | Fatty acid composition and properties of the liver microsomal membrane of rats fed diets enriched with cholesterol. | 1992 | J. Biochem. | pmid:1491012 |
Gimeno RE et al. | Characterization of a heart-specific fatty acid transport protein. | 2003 | J. Biol. Chem. | pmid:12556534 |
Burke A et al. | Specific analysis in plasma and urine of 2,3-dinor-5, 6-dihydro-isoprostane F(2alpha)-III, a metabolite of isoprostane F(2alpha)-III and an oxidation product of gamma-linolenic acid. | 2000 | J. Biol. Chem. | pmid:10644705 |
Weaver KL et al. | Effect of dietary fatty acids on inflammatory gene expression in healthy humans. | 2009 | J. Biol. Chem. | pmid:19359242 |
Kawashima Y et al. | Peroxisome proliferators enhance linoleic acid metabolism in rat liver. Increased biosynthesis of omega 6 polyunsaturated fatty acids. | 1990 | J. Biol. Chem. | pmid:2160962 |
MEAD JF and HOWTON DR | Metabolism of essential fatty acids. VII. Conversion of gamma-linolenic acid to arachidonic acid. | 1957 | J. Biol. Chem. | pmid:13502321 |
ÄŒertÃk M et al. | Simultaneous enrichment of cereals with polyunsaturated fatty acids and pigments by fungal solid state fermentations. | 2013 | J. Biotechnol. | pmid:23583333 |
Bellou S et al. | The olive mill wastewater as substrate for single cell oil production by Zygomycetes. | 2014 | J. Biotechnol. | pmid:24316440 |
Zaitone SA et al. | Effect of evening primrose oil and ω-3 polyunsaturated fatty acids on the cardiovascular risk of celecoxib in rats. | 2011 | J. Cardiovasc. Pharmacol. | pmid:21499116 |
Martin TA et al. | Synergistic regulation of endothelial tight junctions by antioxidant (Se) and polyunsaturated lipid (GLA) via Claudin-5 modulation. | 2006 | J. Cell. Biochem. | pmid:16514648 |
Martin TA et al. | Enhanced tight junction function in human breast cancer cells by antioxidant, selenium and polyunsaturated lipid. | 2007 | J. Cell. Biochem. | pmid:17243118 |
Roemen TH et al. | Quantitative assessment of gamma-linolenic acid in human blood and plasma with capillary gas chromatography. | 1990 | J. Chromatogr. | pmid:2166745 |
Furse RK et al. | Oral administration of gammalinolenic acid, an unsaturated fatty acid with anti-inflammatory properties, modulates interleukin-1beta production by human monocytes. | 2002 | J. Clin. Immunol. | pmid:11998897 |
Puri BK | Long-chain polyunsaturated fatty acids and the pathophysiology of myalgic encephalomyelitis (chronic fatigue syndrome). | 2007 | J. Clin. Pathol. | pmid:16935966 |
Kim JJ et al. | Properties of cholesterol-reduced butter made with beta-cyclodextrin and added evening primrose oil and phytosterols. | 2006 | J. Dairy Sci. | pmid:17106080 |
Clément M et al. | Purification and identification of bovine cheese whey fatty acids exhibiting in vitro antifungal activity. | 2008 | J. Dairy Sci. | pmid:18565910 |
Kanehara S et al. | Clinical effects of undershirts coated with borage oil on children with atopic dermatitis: a double-blind, placebo-controlled clinical trial. | 2007 | J. Dermatol. | pmid:18078406 |
Burnard SL et al. | Cilazapril and dietary gamma-linolenic acid prevent the deficit in sciatic nerve conduction velocity in the streptozotocin diabetic rat. | 1998 Mar-Apr | J. Diabetes Complicat. | pmid:9559483 |
Garland HO et al. | Dietary essential fatty acid supplementation, urinary calcium excretion and reproductive performance in the diabetic pregnant rat. | 1997 | J. Endocrinol. | pmid:9203989 |
Cheng Z et al. | Alteration of prostaglandin production and agonist responsiveness by n-6 polyunsaturated fatty acids in endometrial cells from late-gestation ewes. | 2004 | J. Endocrinol. | pmid:15283685 |
Braddock R et al. | gamma-Linoleic acid and ascorbic acid ameliorate the effects of experimental diabetes on electrolyte and bone homeostasis in pregnant rats. | 2002 | J. Endocrinol. | pmid:12010635 |
Ramandi NF et al. | Central composite design for the optimization of supercritical carbon dioxide fluid extraction of fatty acids from Borago officinalis L. flower. | 2011 Nov-Dec | J. Food Sci. | pmid:22416687 |
Fu J et al. | Hypolipidemic activity in Sprague-Dawley rats and constituents of a novel natural vegetable oil from Cornus wilsoniana fruits. | 2012 | J. Food Sci. | pmid:22747885 |
Li R et al. | Enzymatic Synthesis of Refined Olive Oil-Based Structured Lipid Containing Omega -3 and -6 Fatty Acids for Potential Application in Infant Formula. | 2015 | J. Food Sci. | pmid:26408984 |
Won J et al. | Stability analysis of zinc oxide-nanoencapsulated conjugated linoleic acid and gamma-linolenic acid. | 2008 | J. Food Sci. | pmid:19019122 |
Marra F et al. | Effects of supplementation with unsaturated fatty acids on plasma and membrane lipid composition and platelet function in patients with cirrhosis and defective aggregation. | 1998 | J. Hepatol. | pmid:9566835 |
Bursztyn PG and King MH | Fat induced hypertension in rabbits: the effects of dietary linoleic and linolenic acid. | 1986 | J. Hypertens. | pmid:3029216 |