Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.
To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Manku MS et al. | Essential fatty acids in the plasma phospholipids of patients with atopic eczema. | 1984 | Br. J. Dermatol. | pmid:6329254 |
Sohal RS et al. | Relationship between lipofuscin granules and polyunsaturated fatty acids in the housefly, Musca domestica. | 1984 | Mech. Ageing Dev. | pmid:6330462 |
Hoffman P and Förster W | Effects of sunflowerseed oil, linseed oil, evening primrose oil and hydrogenated palm kernel oil on hypertension development in spontaneously hypertensive rats. | 1983 | Prostaglandins Leukot Med | pmid:6348801 |
Horrobin DF | The role of essential fatty acids and prostaglandins in the premenstrual syndrome. | 1983 | J Reprod Med | pmid:6350579 |
Haslett C et al. | A double-blind evaluation of evening primrose oil as an antiobesity agent. | 1983 | Int J Obes | pmid:6360923 |
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Phillips JS | Oil of the evening primrose. | 1984 | N. Z. Med. J. | pmid:6589527 |
Hanifin JM | Diet, nutrition, and allergy in atopic dermatitis. | 1983 | J. Am. Acad. Dermatol. | pmid:6863636 |
Kábrt J et al. | [Serum lipid concentration in familial hyperlipoproteinemia type IV. Treatment with vitamin C and unsaturated fatty acids]. | 1983 | Cas. Lek. Cesk. | pmid:6871949 |
Kábrt J et al. | [Serum lipid concentrations in familial hyperlipoproteinaemia type IIa. Treatment with unsaturated fatty acids and vitamin C (author's transl)]. | 1982 | Cas. Lek. Cesk. | pmid:7093988 |
Prencipe M et al. | Naudicelle and platelet reactivity in TIA patients. | 1982 | Ital J Neurol Sci | pmid:7166485 |
Karmali RA et al. | Prostaglandins and essential fatty acids in regulation of autoimmunity and development of antibodies to DNA in NZB x NZW F1 mice. | 1981 | Prog. Lipid Res. | pmid:7342118 |
Kunkel SL et al. | Suppression of chronic inflammation by evening primrose oil. | 1981 | Prog. Lipid Res. | pmid:7342138 |
Lindskov R and Petersen CS | [Oral gamma-linoleic acid (Epogam) in the treatment of atopic dermatitis]. | 1995 | Ugeskr. Laeg. | pmid:7483071 |
Hrelia S et al. | Essential fatty acid metabolism in cultured rat cardiomyocytes in response to either N-6 or N-3 fatty acid supplementation. | 1995 | Biochem. Biophys. Res. Commun. | pmid:7488075 |
Rose DP et al. | Effects of linoleic acid and gamma-linolenic acid on the growth and metastasis of a human breast cancer cell line in nude mice and on its growth and invasive capacity in vitro. | 1995 | Nutr Cancer | pmid:7491296 |
Kietzmann M | [Pharmacotherapeutic use of antipruritic drugs in skin diseases]. | 1995 | Tierarztl Prax | pmid:7545832 |
Larsson-Backström C et al. | Effects of dietary alpha- and gamma-linolenic acids on liver fatty acids, lipid metabolism, and survival in sepsis. | 1995 | Shock | pmid:7552772 |
Rossetti RG et al. | Differential regulation of human T lymphocyte protein kinase C activity by unsaturated fatty acids. | 1995 | Clin. Immunol. Immunopathol. | pmid:7554442 |
Manninen P et al. | Separation of gamma- and alpha-linolenic acid containing triacylglycerols by capillary supercritical fluid chromatography. | 1995 | Lipids | pmid:7564922 |
Chajès V et al. | Influence of n-3 fatty acids on the growth of human breast cancer cells in vitro: relationship to peroxides and vitamin-E. | 1995 | Breast Cancer Res. Treat. | pmid:7579484 |
Jiang WG et al. | Regulation of the expression of E-cadherin on human cancer cells by gamma-linolenic acid (GLA). | 1995 | Cancer Res. | pmid:7585549 |
Claassen N et al. | Supplemented gamma-linolenic acid and eicosapentaenoic acid influence bone status in young male rats: effects on free urinary collagen crosslinks, total urinary hydroxyproline, and bone calcium content. | 1995 | Bone | pmid:7626328 |
Das UN et al. | Local application of gamma-linolenic acid in the treatment of human gliomas. | 1995 | Cancer Lett. | pmid:7634242 |
Akahane N et al. | Antithrombotic activity of a symmetrical triglyceride with eicosapentaenoic acid and gamma-linolenic acid in guinea pig mesenteric microvasculature. | 1995 | Thromb. Res. | pmid:7660360 |
Fan YY et al. | Dietary gamma-linolenic acid modulates macrophage-vascular smooth muscle cell interactions. Evidence for a macrophage-derived soluble factor that downregulates DNA synthesis in smooth muscle cells. | 1995 | Arterioscler. Thromb. Vasc. Biol. | pmid:7670954 |
Sherrington EJ et al. | The effect of dietary lipid manipulation on macrophage cell surface molecule expression. | 1995 | Biochem. Soc. Trans. | pmid:7672298 |
Beno DW et al. | Gamma-linolenic acid suppression of hepatic Ito cell mitogenesis: post-PDGF receptor prostaglandin-independent mechanism. | 1993 | Am. J. Physiol. | pmid:7694498 |
Goldfien A | Premenstrual syndrome. | 1994 | Curr Ther Endocrinol Metab | pmid:7704719 |
Jiang WG et al. | Inhibition of hepatocyte growth factor-induced motility and in vitro invasion of human colon cancer cells by gamma-linolenic acid. | 1995 | Br. J. Cancer | pmid:7710939 |
Karasu C et al. | Effects of anti-oxidant treatment on sciatic nerve dysfunction in streptozotocin-diabetic rats; comparison with essential fatty acids. | 1995 | Diabetologia | pmid:7713308 |
Dines KC et al. | Comparison of the effects of evening primrose oil and triglycerides containing gamma-linolenic acid on nerve conduction and blood flow in diabetic rats. | 1995 | J. Pharmacol. Exp. Ther. | pmid:7714803 |
Scholey JW and Mills DE | Dietary fatty acids and the glomerular hemodynamic response to cyclosporine in borderline hypertensive rats. | 1995 | Kidney Int. | pmid:7723248 |
Tate GA and Zurier RB | Suppression of monosodium urate crystal-induced inflammation by black currant seed oil. | 1994 | Agents Actions | pmid:7741038 |
Darlington LG and Ramsey NW | Review of dietary therapy for rheumatoid arthritis. | 1994 | Compr Ther | pmid:7805365 |
BeLieu RM | Mastodynia. | 1994 | Obstet. Gynecol. Clin. North Am. | pmid:7816407 |
Berth-Jones J and Graham-Brown RA | Evening primrose oil. Does not show promise in atopic dermatitis. | 1994 | BMJ | pmid:7819863 |
Horrobin DF and Morse PF | Evening primrose oil and atopic eczema. | 1995 | Lancet | pmid:7823743 |
Araya J and Cagalj A | [Exclusion of alpha-linolenic acid from diets for rats during several generations. I. Effect on reproduction and postnatal growth]. | 1993 | Arch Latinoam Nutr | pmid:7826185 |
Hauben M | Comment: evening primrose oil in the treatment of rheumatoid arthritis--proper application of statistical analysis. | 1994 Jul-Aug | Ann Pharmacother | pmid:7832860 |
Guivernau M et al. | Clinical and experimental study on the long-term effect of dietary gamma-linolenic acid on plasma lipids, platelet aggregation, thromboxane formation, and prostacyclin production. | 1994 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:7846101 |
McCaul JA and Lamey PJ | Multiple oral mucoceles treated with gamma-linolenic acid: report of a case. | 1994 | Br J Oral Maxillofac Surg | pmid:7849001 |
Falconer JS et al. | Polyunsaturated fatty acids in the treatment of weight-losing patients with pancreatic cancer. | 1994 | World Rev Nutr Diet | pmid:7856240 |
Berth-Jones J et al. | Evening primrose oil and atopic eczema. | 1995 | Lancet | pmid:7861894 |
Tulloch I et al. | Evening primrose oil reduces urinary calcium excretion in both normal and hypercalciuric rats. | 1994 | Urol. Res. | pmid:7871634 |
Purasiri P et al. | Modulation of cytokine production in vivo by dietary essential fatty acids in patients with colorectal cancer. | 1994 | Clin. Sci. | pmid:7874864 |
Cartwright-Shamoon JM et al. | A complex biochemical modulation of intestinal ion transport in rats fed on high-fat diets. | 1995 | J. Pediatr. Gastroenterol. Nutr. | pmid:7884616 |
Cameron NE and Cotter MA | Effects of evening primrose oil treatment on sciatic nerve blood flow and endoneurial oxygen tension in streptozotocin-diabetic rats. | 1994 | Acta Diabetol | pmid:7888693 |