Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.
To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Dib A and Carreau JP | Effects of gamma-linolenic acid supplementation on pregnant rats fed a zinc-deficient diet. | 1987 | Ann. Nutr. Metab. | pmid:2821872 |
Huang YS et al. | Protective effect of gamma-linolenic acid on aspirin-induced gastric hemorrhage in rats. | 1987 | Digestion | pmid:3030865 |
Horrobin DF | Essential fatty acids, prostaglandins, and alcoholism: an overview. | 1987 | Alcohol. Clin. Exp. Res. | pmid:3032012 |
Meigel W et al. | [Additional oral therapy of atopic dermatitis with unsaturated fatty acids]. | 1987 | Z. Hautkr. | pmid:2894730 |
Fujiwara F et al. | Fatty acid modification of cultured neuroblastoma cells by gamma linolenic acid relevant to its antitumor effect. | 1987 | Prostaglandins Leukot Med | pmid:2829239 |
McIllmurray MB and Turkie W | Controlled trial of gamma linolenic acid in Duke's C colorectal cancer. | 1987 | Br Med J (Clin Res Ed) | pmid:3036291 |
Huang YS and Horrobin DF | Sex differences in n-3 and n-6 fatty acid metabolism in EFA-depleted rats. | 1987 | Proc. Soc. Exp. Biol. Med. | pmid:3037555 |
el-Ela SH et al. | Effects of dietary primrose oil on mammary tumorigenesis induced by 7,12-dimethylbenz(a)anthracene. | 1987 | Lipids | pmid:3131611 |
Cunnane SC | Hepatic triacylglycerol accumulation induced by ethanol and carbon tetrachloride: interactions with essential fatty acids and prostaglandins. | 1987 | Alcohol. Clin. Exp. Res. | pmid:3032013 |
Ziboh VA and Chapkin RS | Biologic significance of polyunsaturated fatty acids in the skin. | 1987 | Arch Dermatol | pmid:3688908 |
Singh NK et al. | Essential fatty acids and cancer with particular reference to Hodgkin's disease. | 1987 | J Assoc Physicians India | pmid:3693269 |
Das UN et al. | Beneficial effect of essential fatty acids in cirrhosis of the liver. | 1987 | J Assoc Physicians India | pmid:3693270 |
Papanikolaou N | Alteration of mercuric chloride-induced autoimmune glomerulonephritis in brown-Norway rats by herring oil, evening primrose oil and OKY-046 a selective TXA-synthetase inhibitor. | 1987 | Prostaglandins Leukot Med | pmid:3475724 |
Papanikolaou N et al. | Effect of thromboxane A2-synthetase inhibitor OKY-046 and evening primrose oil (Efamol) on mercuric chloride induced autoimmune glomerulonephritis in Brown-Norway rats. | 1987 | Prog. Clin. Biol. Res. | pmid:3671393 |
Guenther L and Wexler D | Efamol in the treatment of atopic dermatitis. | 1987 | J. Am. Acad. Dermatol. | pmid:3680673 |
Choi YS and Sugano M | Effects of dietary alpha- and gamma-linolenic acid on lipid metabolism in young and adult rats. | 1988 | Ann. Nutr. Metab. | pmid:2903713 |
Abou-el-Ela SH et al. | Eicosanoid synthesis in 7,12-dimethylbenz(a)anthracene-induced mammary carcinomas in Sprague-Dawley rats fed primrose oil, menhaden oil or corn oil diet. | 1988 | Lipids | pmid:3143882 |
Cronholm T et al. | Influence of dietary fats on pancreatic phospholipids of chronically ethanol-treated rats. | 1988 | Lipids | pmid:2846981 |
Tate GA et al. | Suppression of monosodium urate crystal-induced acute inflammation by diets enriched with gamma-linolenic acid and eicosapentaenoic acid. | 1988 | Arthritis Rheum. | pmid:2848532 |
Williams JH | The use of gamma linolenic acid, linoleic acid and natural vitamin E for the treatment of multicentric lymphoma in two dogs. | 1988 | J S Afr Vet Assoc | pmid:2848946 |
Belch JJ et al. | Effects of altering dietary essential fatty acids on requirements for non-steroidal anti-inflammatory drugs in patients with rheumatoid arthritis: a double blind placebo controlled study. | 1988 | Ann. Rheum. Dis. | pmid:2833184 |
Chaud M et al. | Gamma-linolenic acid improves the constancy of contractions in uteri from sprayed rats and is metabolized to prostaglandin E1 but not to bisenoic prostanoids. | 1988 | Prostaglandins | pmid:2836889 |
Wade AE et al. | Effect of 7,12-dimethylbenz(a)anthracene administration on hepatic drug metabolizing enzymes in female rats fed corn, primrose, and menhaden oils. | 1988 | Drug Nutr Interact | pmid:3149238 |
Biagi PL et al. | A long-term study on the use of evening primrose oil (Efamol) in atopic children. | 1988 | Drugs Exp Clin Res | pmid:3048952 |
Bordoni A et al. | Evening primrose oil (Efamol) in the treatment of children with atopic eczema. | 1988 | Drugs Exp Clin Res | pmid:3048953 |
van Doormaal JJ et al. | Effects of short-term high dose intake of evening primrose oil on plasma and cellular fatty acid compositions, alpha-tocopherol levels, and erythropoiesis in normal and type 1 (insulin-dependent) diabetic men. | 1988 | Diabetologia | pmid:3065111 |
Miller CC and Ziboh VA | Gammalinolenic acid-enriched diet alters cutaneous eicosanoids. | 1988 | Biochem. Biophys. Res. Commun. | pmid:2841938 |
Novak E | Maintaining remission of Crohn's disease. | 1988 | CMAJ | pmid:3383034 |
Greaves MW and Corbett MF | Treatment of atopic eczema with evening primrose oil. | 1988 | Br. J. Dermatol. | pmid:3355786 |
Darlington LG | Do diets rich in polyunsaturated fatty acids affect disease activity in rheumatoid arthritis? | 1988 | Ann. Rheum. Dis. | pmid:3281607 |
Barcelli UO et al. | A diet containing n-3 and n-6 fatty acids favorably alters the renal phospholipids, eicosanoid synthesis and plasma lipids in nephrotic rats. | 1988 | Lipids | pmid:3237005 |
Julu PO | Essential fatty acids prevent slowed nerve conduction in streptozotocin diabetic rats. | 1988 Oct-Dec | J Diabet Complications | pmid:2853165 |
Bates D | Lipids and multiple sclerosis. | 1989 | Biochem. Soc. Trans. | pmid:2546837 |
Santoli D and Zurier RB | Prostaglandin E precursor fatty acids inhibit human IL-2 production by a prostaglandin E-independent mechanism. | 1989 | J. Immunol. | pmid:2545787 |
Watkins BA | Levels of dihomo-gamma-linolenate are depressed in heart phosphatidylcholine and phosphatidylethanolamine in the biotin-deficient chick. | 1989 | Poult. Sci. | pmid:2547210 |
Uccella R et al. | [Action of evening primrose oil on cardiovascular risk factors in insulin-dependent diabetics]. | 1989 | Clin Ter | pmid:2548804 |
Melnik BC and Plewig G | Is the origin of atopy linked to deficient conversion of omega-6-fatty acids to prostaglandin E1? | 1989 | J. Am. Acad. Dermatol. | pmid:2550526 |
Tate G et al. | Suppression of acute and chronic inflammation by dietary gamma linolenic acid. | 1989 | J. Rheumatol. | pmid:2550629 |
Arnold LE et al. | Gamma-linolenic acid for attention-deficit hyperactivity disorder: placebo-controlled comparison to D-amphetamine. | 1989 | Biol. Psychiatry | pmid:2539203 |
Ishikawa T et al. | Effects of gammalinolenic acid on plasma lipoproteins and apolipoproteins. | 1989 | Atherosclerosis | pmid:2540757 |
Botha JH et al. | The role of prostaglandins in the inhibition of cultured carcinoma cell growth produced by gamma-linolenic acid. | 1989 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:2541450 |
McCollum JR | FDA alert on evening primrose oil. | 1989 | J Am Diet Assoc | pmid:2542387 |
Morse PF et al. | Meta-analysis of placebo-controlled studies of the efficacy of Epogam in the treatment of atopic eczema. Relationship between plasma essential fatty acid changes and clinical response. | 1989 | Br. J. Dermatol. | pmid:2667620 |
Jäntti J et al. | Evening primrose oil in rheumatoid arthritis: changes in serum lipids and fatty acids. | 1989 | Ann. Rheum. Dis. | pmid:2649022 |
Moodley J and Norman RJ | Attempts at dietary alteration of prostaglandin pathways in the management of pre-eclampsia. | 1989 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:2608693 |
Wilson JH et al. | The effect of very low energy diets on the fatty acid composition of serum lipids. | 1989 | Int J Obes | pmid:2613428 |
Wright S and Bolton C | Breast milk fatty acids in mothers of children with atopic eczema. | 1989 | Br. J. Nutr. | pmid:2557889 |
Melnik B and Plewig G | [A new concept of the etiopathogenesis and prevention of atopic dermatitis]. | 1989 | Hautarzt | pmid:2558092 |
Tomlinson DR et al. | Essential fatty acid treatment--effects on nerve conduction, polyol pathway and axonal transport in streptozotocin diabetic rats. | 1989 | Diabetologia | pmid:2477293 |
Horrobin DF | Effects of evening primrose oil in rheumatoid arthritis. | 1989 | Ann. Rheum. Dis. | pmid:2688567 |