gamma-Linolenic acid

Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.

Cross Reference

Introduction

To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid

MeSH term MeSH ID Detail
Weight Gain D015430 101 associated lipids
Cardiovascular Diseases D002318 24 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Glioma D005910 112 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Leukemia P388 D007941 43 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Thrombosis D013927 49 associated lipids
Hyperplasia D006965 34 associated lipids
Arteriosclerosis D001161 86 associated lipids
Per page 10 20 50 100 | Total 85

PubChem Associated disorders and diseases

What pathways are associated with gamma-Linolenic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with gamma-Linolenic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with gamma-Linolenic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with gamma-Linolenic acid

Download all related citations
Per page 10 20 50 100 | Total 1121
Authors Title Published Journal PubMed Link
Harbige LS et al. Prevention of experimental autoimmune encephalomyelitis in Lewis rats by a novel fungal source of gamma-linolenic acid. 1995 Br. J. Nutr. pmid:8541276
Burgess NA et al. Evaluation of four animal models of intrarenal calcium deposition and assessment of the influence of dietary supplementation with essential fatty acids on calcification. 1995 Urol. Res. pmid:8533210
Giamarellos-Bourboulis EJ et al. In-vitro inhibitory activity of gamma-linolenic acid on Escherichia coli strains and its influence on their susceptibilities to various antimicrobial agents. 1995 J. Antimicrob. Chemother. pmid:8522462
Dines CD et al. Nerve function in galactosaemic rats: effects of evening primrose oil and doxazosin. 1995 Eur. J. Pharmacol. pmid:8521914
Collins A et al. Essential fatty acids in the treatment of premenstrual syndrome. 1993 Obstet Gynecol pmid:8416468
Phinney SD et al. Abnormal polyunsaturated lipid metabolism in the obese Zucker rat, with partial metabolic correction by gamma-linolenic acid administration. 1993 Metab. Clin. Exp. pmid:8412765
Melnik B and Plewig G [External treatment of atopic eczema with gamma-linolenic acid?]. 1993 Hautarzt pmid:8407331
Oliwiecki S et al. The effect of essential fatty acids on epidermal atrophy due to topical steroids. 1993 Clin. Exp. Dermatol. pmid:8403467
Cantrill RC et al. Concentration-dependent effect of iron on gamma-linolenic acid toxicity in ZR-75-1 human breast tumor cells in culture. 1993 Cancer Lett. pmid:8402582
Cameron NE et al. The effects of evening primrose oil on nerve function and capillarization in streptozotocin-diabetic rats: modulation by the cyclo-oxygenase inhibitor flurbiprofen. 1993 Br. J. Pharmacol. pmid:8401950
Tollesson A and Frithz A Borage oil, an effective new treatment for infantile seborrhoeic dermatitis. 1993 Br. J. Dermatol. pmid:8396411
Kinchington D et al. Lithium gamma-linolenate-induced cytotoxicity against cells chronically infected with HIV-1. 1993 FEBS Lett. pmid:8396048
Galle AM et al. Biosynthesis of gamma-linolenic acid in developing seeds of borage (Borago officinalis L.). 1993 Biochim. Biophys. Acta pmid:8394742
Cerin A et al. Hormonal and biochemical profiles of premenstrual syndrome. Treatment with essential fatty acids. 1993 Acta Obstet Gynecol Scand pmid:8392261
Hopewell JW et al. The modulation of radiation-induced damage to pig skin by essential fatty acids. 1993 Br. J. Cancer pmid:8391301
Bala KV et al. Inhibition of methyl mercury chloride-induced chromosomal damage by gamma-linolenic acid. 1993 Food Chem. Toxicol. pmid:8390392
Karmali RA et al. Plant and marine n-3 fatty acids inhibit experimental metastasis of rat mammary adenocarcinoma cells. 1993 Prostaglandins Leukot. Essent. Fatty Acids pmid:8388566
Takeda S et al. Mechanism of lipid peroxidation in cancer cells in response to gamma-linolenic acid (GLA) analyzed by GC-MS(I): Conjugated dienes with peroxyl (or hydroperoxyl) groups and cell-killing effects. 1993 Jan-Feb Anticancer Res. pmid:8386494
Horrobin DF Fatty acid metabolism in health and disease: the role of delta-6-desaturase. 1993 Am. J. Clin. Nutr. pmid:8386433
Miura Y et al. Production of gamma-linolenic acid from the marine green alga Chlorella sp. NKG 042401. 1993 FEMS Microbiol. Lett. pmid:8386122
Plumb JA et al. Effect of polyunsaturated fatty acids on the drug sensitivity of human tumour cell lines resistant to either cisplatin or doxorubicin. 1993 Br. J. Cancer pmid:8385976
González CA et al. Borage consumption as a possible gastric cancer protective factor. 1993 Mar-Apr Cancer Epidemiol. Biomarkers Prev. pmid:8385521
Poisson JP et al. Effect of salt-loading and spontaneous hypertension on in vitro metabolism of [1-14C]linoleic and [2-14C]dihomo-gamma-linolenic acids. 1993 Biochem. Med. Metab. Biol. pmid:8382502
Horrobin DF The effects of gamma-linolenic acid on breast pain and diabetic neuropathy: possible non-eicosanoid mechanisms. 1993 Prostaglandins Leukot. Essent. Fatty Acids pmid:8380930
Keen H et al. Treatment of diabetic neuropathy with gamma-linolenic acid. The gamma-Linolenic Acid Multicenter Trial Group. 1993 Diabetes Care pmid:8380765
Leyton E Disagreeing on how to treat CFS patients. 1993 Can Fam Physician pmid:8347205
Stevens EJ et al. Essential fatty acid treatment prevents nerve ischaemia and associated conduction anomalies in rats with experimental diabetes mellitus. 1993 Diabetologia pmid:8314443
Joe LA and Hart LL Evening primrose oil in rheumatoid arthritis. 1993 Ann Pharmacother pmid:8305783
Harvey RG A comparison of evening primrose oil and sunflower oil for the management of papulocrustous dermatitis in cats. 1993 Vet. Rec. pmid:8303807
Ramanathan R et al. Effects of gamma-linolenic acid, flavonoids, and vitamins on cytotoxicity and lipid peroxidation. 1994 Free Radic. Biol. Med. pmid:8299995
Harvey RG Effect of varying proportions of evening primrose oil and fish oil on cats with crusting dermatosis ('miliary dermatitis') 1993 Vet. Rec. pmid:8280288
Dehaut F et al. n-6 polyunsaturated fatty acids increase the neurite length of PC12 cells and embryonic chick motoneurons. 1993 Neurosci. Lett. pmid:8272254
Dines KC et al. Contrasting effects of treatment with omega-3 and omega-6 essential fatty acids on peripheral nerve function and capillarization in streptozotocin-diabetic rats. 1993 Diabetologia pmid:8270127
Engler MM Comparative study of diets enriched with evening primrose, black currant, borage or fungal oils on blood pressure and pressor responses in spontaneously hypertensive rats. 1993 Prostaglandins Leukot. Essent. Fatty Acids pmid:8259378
Stevens EJ et al. Prostacyclin release in experimental diabetes: effects of evening primrose oil. 1993 Prostaglandins Leukot. Essent. Fatty Acids pmid:8248277
Laivuori H et al. Dietary supplementation with primrose oil or fish oil does not change urinary excretion of prostacyclin and thromboxane metabolites in pre-eclamptic women. 1993 Prostaglandins Leukot. Essent. Fatty Acids pmid:8248275
Karlstad MD et al. Effect of intravenous lipid emulsions enriched with gamma-linolenic acid on plasma n-6 fatty acids and prostaglandin biosynthesis after burn and endotoxin injury in rats. 1993 Crit. Care Med. pmid:8222692
Leventhal LJ et al. Treatment of rheumatoid arthritis with gammalinolenic acid. 1993 Ann. Intern. Med. pmid:8214997
Jamal GA The use of gamma linolenic acid in the prevention and treatment of diabetic neuropathy. 1994 Diabet. Med. pmid:8200197
Devi MA and Das NP Antiproliferative effect of polyunsaturated fatty acids and interleukin-2 on normal and abnormal human lymphocytes. 1994 Experientia pmid:8194587
Christophe A et al. Effect of administration of gamma-linolenic acid on the fatty acid composition of serum phospholipids and cholesteryl esters in patients with cystic fibrosis. 1994 Ann. Nutr. Metab. pmid:8185286
Wetzig NR Mastalgia: a 3 year Australian study. 1994 Aust N Z J Surg pmid:8179529
Maaswinkel-Mooij PD et al. Unsuccessful dietary treatment of Sjögren-Larsson syndrome. 1994 J. Pediatr. pmid:8176565
Morphake P et al. Alteration of cyclosporine (CsA)-induced nephrotoxicity by gamma linolenic acid (GLA) and eicosapentaenoic acid (EPA) in Wistar rats. 1994 Prostaglandins Leukot. Essent. Fatty Acids pmid:8146206
Takada R et al. Dietary gamma-linolenic acid-enriched oil reduces body fat content and induces liver enzyme activities relating to fatty acid beta-oxidation in rats. 1994 J. Nutr. pmid:8145067
Chenoy R et al. Effect of oral gamolenic acid from evening primrose oil on menopausal flushing. 1994 BMJ pmid:8136666
Phinney S Potential risk of prolonged gamma-linolenic acid use. 1994 Ann. Intern. Med. pmid:8135457
Bond R and Lloyd DH Combined treatment with concentrated essential fatty acids and prednisolone in the management of canine atopy. 1994 Vet. Rec. pmid:8135003
Shield MJ et al. Essential fatty acid supplementation in atopic dermatitis. 1993 Lancet pmid:8101623
Berth-Jones J and Graham-Brown RA Placebo-controlled trial of essential fatty acid supplementation in atopic dermatitis. 1993 Lancet pmid:8099640