gamma-Linolenic acid

Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.

Cross Reference

Introduction

To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid

MeSH term MeSH ID Detail
Neuroblastoma D009447 66 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Psoriasis D011565 47 associated lipids
Alcoholism D000437 27 associated lipids
Bacteriuria D001437 7 associated lipids
Respiratory Insufficiency D012131 10 associated lipids
Erectile Dysfunction D007172 19 associated lipids
Liver Cirrhosis, Alcoholic D008104 17 associated lipids
Respiratory Distress Syndrome, Adult D012128 15 associated lipids
Seizures D012640 87 associated lipids
Per page 10 20 50 100 | Total 85

PubChem Associated disorders and diseases

What pathways are associated with gamma-Linolenic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with gamma-Linolenic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with gamma-Linolenic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with gamma-Linolenic acid

Download all related citations
Per page 10 20 50 100 | Total 1121
Authors Title Published Journal PubMed Link
Noli C et al. Conjugated linoleic acid and black currant seed oil in the treatment of canine atopic dermatitis: a preliminary report. 2007 Vet. J. pmid:16495095
Sýkora J et al. High-performance liquid chromatography with nuclear magnetic resonance detection--A method for quantification of alpha- and gamma-linolenic acids in their mixtures with free fatty acids. 2007 J Chromatogr A pmid:17157864
Pitel S et al. At low doses, a gamma-linolenic acid-lipoic acid conjugate is more effective than docosahexaenoic acid-enriched phospholipids in preventing neuropathy in diabetic rats. 2007 J. Nutr. pmid:17237313
Curtis L High-quality enteral nutrition essential for reducing morbidity and mortality in acute care patients. 2007 Crit. Care Med. pmid:17421112
Ortiz-Leyba C and Garnacho-Montero J Saving lives in severe sepsis with the help of enteral nutrition. 2007 Crit. Care Med. pmid:17421113
Kanehara S et al. Clinical effects of undershirts coated with borage oil on children with atopic dermatitis: a double-blind, placebo-controlled clinical trial. 2007 J. Dermatol. pmid:18078406
Vrinten P et al. Production of polyunsaturated fatty acids in transgenic plants. 2007 Biotechnol. Genet. Eng. Rev. pmid:18059637
Stolyhwo A and Mol J Changes in the content of gamma-linolenic C18:3 (n-6) and stearidonic C18:4 (n-3) acids in developing seeds of viper's bugloss Echium vulgare L. 2007 Acta Biochim. Pol. pmid:18066400
Saied GM et al. Low intensity laser therapy is comparable to bromocriptine-evening primrose oil for the treatment of cyclical mastalgia in Egyptian females. 2007 Tanzan Health Res Bull pmid:18087899
Poulsen RC et al. Specific effects of gamma-linolenic, eicosapentaenoic, and docosahexaenoic ethyl esters on bone post-ovariectomy in rats. 2007 Calcif. Tissue Int. pmid:18008020
Lindmark L and Clough P A 5-month open study with long-chain polyunsaturated fatty acids in dyslexia. 2007 J Med Food pmid:18158838
Guo SX et al. [Influence of methyl esterification on the ultraviolet absorption of gamma-linolenic acid]. 2007 Zhong Yao Cai pmid:18236761
Puri BK The safety of evening primrose oil in epilepsy. 2007 Prostaglandins Leukot. Essent. Fatty Acids pmid:17764919
Pinna A et al. Effect of oral linoleic and gamma-linolenic acid on meibomian gland dysfunction. 2007 Cornea pmid:17413949
Lu H et al. [Cloning and expression of a delta6-fatty acid desaturase gene from Rhizopus stolonifer in Saccharomyces cervisiae]. 2007 Wei Sheng Wu Xue Bao pmid:17436625
Cho HS et al. Anti-wrinkling effects of the mixture of vitamin C, vitamin E, pycnogenol and evening primrose oil, and molecular mechanisms on hairless mouse skin caused by chronic ultraviolet B irradiation. 2007 Photodermatol Photoimmunol Photomed pmid:17803593
Guil-Guerrero JL et al. Gamma-linolenic acid from Cape Verdian Boraginaceae. 2006 Nat. Prod. Res. pmid:16286301
Umeda-Sawada R et al. Distribution and metabolism of dihomo-gamma-linolenic acid (DGLA, 20:3n-6) by oral supplementation in rats. 2006 Biosci. Biotechnol. Biochem. pmid:16960355
Kim J et al. Comparative effect of gromwell (Lithospermum erythrorhizon) extract and borage oil on reversing epidermal hyperproliferation in guinea pigs. 2006 Biosci. Biotechnol. Biochem. pmid:16960390
Hatanaka E et al. Systematic study on ROS production induced by oleic, linoleic, and gamma-linolenic acids in human and rat neutrophils. 2006 Free Radic. Biol. Med. pmid:16962937
Pontes-Arruda A et al. Effects of enteral feeding with eicosapentaenoic acid, gamma-linolenic acid, and antioxidants in mechanically ventilated patients with severe sepsis and septic shock. 2006 Crit. Care Med. pmid:16850002
Fakas S et al. Lipids of Cunninghamella echinulata with emphasis to gamma-linolenic acid distribution among lipid classes. 2006 Appl. Microbiol. Biotechnol. pmid:16850299
Kong X et al. Induction of apoptosis in K562/ADM cells by gamma-linolenic acid involves lipid peroxidation and activation of caspase-3. 2006 Chem. Biol. Interact. pmid:16857180
Pham H et al. Dietary gamma-linolenate attenuates tumor growth in a rodent model of prostatic adenocarcinoma via suppression of elevated generation of PGE(2) and 5S-HETE. 2006 Prostaglandins Leukot. Essent. Fatty Acids pmid:16567086
Singer P et al. Benefit of an enteral diet enriched with eicosapentaenoic acid and gamma-linolenic acid in ventilated patients with acute lung injury. 2006 Crit. Care Med. pmid:16484911
Das UN and Rao KP Effect of gamma-linolenic acid and prostaglandins E1 on gamma-radiation and chemical-induced genetic damage to the bone marrow cells of mice. 2006 Prostaglandins Leukot. Essent. Fatty Acids pmid:16488586
Martin TA et al. Synergistic regulation of endothelial tight junctions by antioxidant (Se) and polyunsaturated lipid (GLA) via Claudin-5 modulation. 2006 J. Cell. Biochem. pmid:16514648
Pacht ER Enteral therapy to decrease morbidity and improve survival in acute respiratory distress syndrome: its time has come. 2006 Crit. Care Med. pmid:16921322
Arab K et al. Conjugated linoleic acid, unlike other unsaturated fatty acids, strongly induces glutathione synthesis without any lipoperoxidation. 2006 Br. J. Nutr. pmid:17092368
Das UN Tumoricidal and anti-angiogenic actions of gamma-linolenic acid and its derivatives. 2006 Curr Pharm Biotechnol pmid:17168663
Morse NL and Clough PM A meta-analysis of randomized, placebo-controlled clinical trials of Efamol evening primrose oil in atopic eczema. Where do we go from here in light of more recent discoveries? 2006 Curr Pharm Biotechnol pmid:17168667
Kapoor R and Huang YS Gamma linolenic acid: an antiinflammatory omega-6 fatty acid. 2006 Curr Pharm Biotechnol pmid:17168669
DeMichele SJ et al. A nutritional strategy to improve oxygenation and decrease morbidity in patients who have acute respiratory distress syndrome. 2006 Respir Care Clin N Am pmid:17150431
Kim JJ et al. Properties of cholesterol-reduced butter made with beta-cyclodextrin and added evening primrose oil and phytosterols. 2006 J. Dairy Sci. pmid:17106080
Gasperino J and Kvetan V Acute lung injury and nutritional support. 2006 Crit. Care Med. pmid:16550085
Yu Z et al. Induction of renal cytochrome P450 arachidonic acid epoxygenase activity by dietary gamma-linolenic acid. 2006 J. Pharmacol. Exp. Ther. pmid:16421287
Tocher DR et al. Effect of diets enriched in Delta6 desaturated fatty acids (18:3n-6 and 18:4n-3), on growth, fatty acid composition and highly unsaturated fatty acid synthesis in two populations of Arctic charr (Salvelinus alpinus L.). 2006 Comp. Biochem. Physiol. B, Biochem. Mol. Biol. pmid:16630735
Kitz R et al. Impact of early dietary gamma-linolenic acid supplementation on atopic eczema in infancy. 2006 Pediatr Allergy Immunol pmid:16618360
Chen YC et al. Therapeutic effect of topical gamma-linolenic acid on refractory uremic pruritus. 2006 Am. J. Kidney Dis. pmid:16797388
Miles EA et al. Self-reported health problems in young male subjects supplementing their diet with oils rich in eicosapentaenoic, gamma-linolenic and stearidonic acids. 2006 Prostaglandins Leukot. Essent. Fatty Acids pmid:16820286
Hongsthong A et al. Revealing the complementation of ferredoxin by cytochrome b (5) in the Spirulina- (6)-desaturation reaction by N-terminal fusion and co-expression of the fungal-cytochrome b (5) domain and Spirulina- (6)-acyl-lipid desaturase. 2006 Appl. Microbiol. Biotechnol. pmid:16575563
Das UN Re: Effect of gamma-linolenic acid on the transcriptional activity of the Her-2/neu (erbB-2) oncogene. 2006 J. Natl. Cancer Inst. pmid:16705127
Azevedo-Martins AK et al. Fatty acid-induced toxicity and neutral lipid accumulation in insulin-producing RINm5F cells. 2006 Toxicol In Vitro pmid:16644178
Verhoeven MO et al. Effect of a combination of isoflavones and Actaea racemosa Linnaeus on climacteric symptoms in healthy symptomatic perimenopausal women: a 12-week randomized, placebo-controlled, double-blind study. 2005 Jul-Aug Menopause pmid:16037756
Goyal A and Mansel RE A randomized multicenter study of gamolenic acid (Efamast) with and without antioxidant vitamins and minerals in the management of mastalgia. 2005 Jan-Feb Breast J pmid:15647077
Efstathopoulos N et al. N-6 polyunsaturated fatty acids confer hemodynamic stability in an experimental model of multiple trauma. 2005 Prostaglandins Leukot. Essent. Fatty Acids pmid:15850717
Vang K and Ziboh VA 15-lipoxygenase metabolites of gamma-linolenic acid/eicosapentaenoic acid suppress growth and arachidonic acid metabolism in human prostatic adenocarcinoma cells: possible implications of dietary fatty acids. 2005 Prostaglandins Leukot. Essent. Fatty Acids pmid:15850718
Taweechaisupapong S et al. Evening primrose oil effects on osteoclasts during tooth movement. 2005 Angle Orthod pmid:15898373
Na-Ranong S et al. Substrate specificity and preference of Delta6-desaturase of Mucor rouxii. 2005 FEBS Lett. pmid:15862319
Takeno S et al. Molecular evidence that the rate-limiting step for the biosynthesis of arachidonic acid in Mortierella alpina is at the level of an elongase. 2005 Lipids pmid:15825827