gamma-Linolenic acid

Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.

Cross Reference

Introduction

To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid

MeSH term MeSH ID Detail
Neuroblastoma D009447 66 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Psoriasis D011565 47 associated lipids
Alcoholism D000437 27 associated lipids
Bacteriuria D001437 7 associated lipids
Respiratory Insufficiency D012131 10 associated lipids
Erectile Dysfunction D007172 19 associated lipids
Liver Cirrhosis, Alcoholic D008104 17 associated lipids
Respiratory Distress Syndrome, Adult D012128 15 associated lipids
Seizures D012640 87 associated lipids
Per page 10 20 50 100 | Total 85

PubChem Associated disorders and diseases

What pathways are associated with gamma-Linolenic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with gamma-Linolenic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with gamma-Linolenic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with gamma-Linolenic acid

Download all related citations
Per page 10 20 50 100 | Total 1121
Authors Title Published Journal PubMed Link
Liu FX et al. [Study on the encapsulation technique of high purity gamma-linolenic acid, part 1--Single factor, and two-factor tests for encapsulation process]. 2005 Zhongguo Zhong Yao Za Zhi pmid:15810447
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Vahedi K et al. A 3-month double-blind randomised study comparing an olive oil- with a soyabean oil-based intravenous lipid emulsion in home parenteral nutrition patients. 2005 Br. J. Nutr. pmid:16351767
Menendez JA et al. Effect of gamma-linolenic acid on the transcriptional activity of the Her-2/neu (erbB-2) oncogene. 2005 J. Natl. Cancer Inst. pmid:16264182
Heard CM et al. Preferential pi-pi complexation between tamoxifen and borage oil/gamma linolenic acid: transcutaneous delivery and NMR spectral modulation. 2005 Int J Pharm pmid:16115741
Oikawa D et al. Modification of skin composition by conjugated linoleic acid alone or with combination of other fatty acids in mice. 2005 Br. J. Nutr. pmid:16115363
Cerolini S et al. Dietary fish and evening primrose oil with vitamin E effects on semen variables in cockerels. 2005 Br. Poult. Sci. pmid:15957443
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Gillis RC et al. Inhibition of 5-lipoxygenase induces cell death in anti-inflammatory fatty acid-treated HL-60 cells. 2004 Sep-Oct JPEN J Parenter Enteral Nutr pmid:15449569
Torres CF et al. Lipase-catalyzed ethanolysis of borage oil: a kinetic study. 2004 May-Jun Biotechnol. Prog. pmid:15176879
Kavanagh T et al. Eicosapentaenoic acid and gamma-linolenic acid increase hippocampal concentrations of IL-4 and IL-10 and abrogate lipopolysaccharide-induced inhibition of long-term potentiation. 2004 Prostaglandins Leukot. Essent. Fatty Acids pmid:15041032
Del Castillo ML et al. Fatty acid content and juice characteristics in black currant (Ribes nigrum L.) genotypes. 2004 J. Agric. Food Chem. pmid:14969555
Menendez JA et al. Omega-6 polyunsaturated fatty acid gamma-linolenic acid (18:3n-6) is a selective estrogen-response modulator in human breast cancer cells: gamma-linolenic acid antagonizes estrogen receptor-dependent transcriptional activity, transcriptionally represses estrogen receptor expression and synergistically enhances tamoxifen and ICI 182,780 (Faslodex) efficacy in human breast cancer cells. 2004 Int. J. Cancer pmid:15027132
Nakanishi T et al. Gamma-linolenic acid prevents conjugated linoleic acid-induced fatty liver in mice. 2004 Nutrition pmid:15043857
Li MC et al. [Expression of delta6-fatty acid desaturase gene from Mortierella alpina in Pichia pastoris]. 2004 Sheng Wu Gong Cheng Xue Bao pmid:16108486
Zhang Q et al. [Progress on molecular biology of delta6-fatty acid desaturases]. 2004 Sheng Wu Gong Cheng Xue Bao pmid:15971598
Cheng Z et al. Alteration of prostaglandin production and agonist responsiveness by n-6 polyunsaturated fatty acids in endometrial cells from late-gestation ewes. 2004 J. Endocrinol. pmid:15283685
Papanikolaou S et al. Repression of reserve lipid turnover in Cunninghamella echinulata and Mortierella isabellina cultivated in multiple-limited media. 2004 J. Appl. Microbiol. pmid:15357737
Papanikolaou S et al. Single cell oil (SCO) production by Mortierella isabellina grown on high-sugar content media. 2004 Bioresour. Technol. pmid:15288271
Harrison RA et al. Who and how many people are taking herbal supplements? A survey of 21,923 adults. 2004 Int J Vitam Nutr Res pmid:15296076
Crowe DL and Chandraratna RA A retinoid X receptor (RXR)-selective retinoid reveals that RXR-alpha is potentially a therapeutic target in breast cancer cell lines, and that it potentiates antiproliferative and apoptotic responses to peroxisome proliferator-activated receptor ligands. 2004 Breast Cancer Res. pmid:15318936
Hirawa N and Umemura S [Prostaglandin/bradykinin]. 2004 Nippon Rinsho pmid:15250292
Bruder ED et al. Metabolic consequences of hypoxia from birth and dexamethasone treatment in the neonatal rat: comprehensive hepatic lipid and fatty acid profiling. 2004 Endocrinology pmid:15271879
Pham H et al. Suppression of cyclooxygenase-2 overexpression by 15S-hydroxyeicosatrienoic acid in androgen-dependent prostatic adenocarcinoma cells. 2004 Int. J. Cancer pmid:15197770
Johnston GA et al. The use of dietary manipulation by parents of children with atopic dermatitis. 2004 Br. J. Dermatol. pmid:15214908
Saevik BK et al. A randomized, controlled study to evaluate the steroid sparing effect of essential fatty acid supplementation in the treatment of canine atopic dermatitis. 2004 Vet. Dermatol. pmid:15214949
Ziboh VA et al. Suppression of leukotriene B4 generation by ex-vivo neutrophils isolated from asthma patients on dietary supplementation with gammalinolenic acid-containing borage oil: possible implication in asthma. 2004 Clin. Dev. Immunol. pmid:15154607
Agombar A et al. An aqueous formulation of gamma-linolenic acid with anti-proliferative action on human pancreatic cancer cell lines. 2004 Anticancer Drugs pmid:15075672
Dokholyan RS et al. A trial of omega-3 fatty acids for prevention of hypertension. 2004 Am. J. Cardiol. pmid:15081453
van Gool CJ et al. Oral essential fatty acid supplementation in atopic dermatitis-a meta-analysis of placebo-controlled trials. 2004 Br. J. Dermatol. pmid:15099370
Leaver HA et al. Intracellular oxidation by human glioma cell populations: effect of arachidonic acid. 2004 Prostaglandins Leukot. Essent. Fatty Acids pmid:15062847
Miles EA et al. The influence of different combinations of gamma-linolenic, stearidonic and eicosapentaenoic acids on the fatty acid composition of blood lipids and mononuclear cells in human volunteers. 2004 Prostaglandins Leukot. Essent. Fatty Acids pmid:15120716
Das UN From bench to the clinic: gamma-linolenic acid therapy of human gliomas. 2004 Prostaglandins Leukot. Essent. Fatty Acids pmid:15120717
Gallagher S Omega 3 oils and pregnancy. 2004 Midwifery Today Int Midwife pmid:15124319
Karia C et al. Simultaneous permeation of tamoxifen and gamma linolenic acid across excised human skin. Further evidence of the permeation of solvated complexes. 2004 Int J Pharm pmid:15129999
Menendez JA et al. Overexpression and hyperactivity of breast cancer-associated fatty acid synthase (oncogenic antigen-519) is insensitive to normal arachidonic fatty acid-induced suppression in lipogenic tissues but it is selectively inhibited by tumoricidal alpha-linolenic and gamma-linolenic fatty acids: a novel mechanism by which dietary fat can alter mammary tumorigenesis. 2004 Int. J. Oncol. pmid:15138577
Shotton HR et al. Prevention and partial reversal of diabetes-induced changes in enteric nerves of the rat ileum by combined treatment with alpha-lipoic acid and evening primrose oil. 2004 Auton Neurosci pmid:15109939
Fewtrell MS et al. Randomized, double-blind trial of long-chain polyunsaturated fatty acid supplementation with fish oil and borage oil in preterm infants. 2004 J. Pediatr. pmid:15069395
Puri BK The clinical advantages of cold-pressed non-raffinated evening primrose oil over refined preparations. 2004 Med. Hypotheses pmid:14729014
Zhang Q et al. Identification and characterization of a novel Delta6-fatty acid desaturase gene from Rhizopus arrhizus. 2004 FEBS Lett. pmid:14706830
Menendez JA et al. Omega-6 polyunsaturated fatty acid gamma-linolenic acid (18:3n-6) enhances docetaxel (Taxotere) cytotoxicity in human breast carcinoma cells: Relationship to lipid peroxidation and HER-2/neu expression. 2004 Oncol. Rep. pmid:15138562