gamma-Linolenic acid

Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.

Cross Reference

Introduction

To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid

MeSH term MeSH ID Detail
Carcinoma 256, Walker D002279 22 associated lipids
Neoplasm Invasiveness D009361 23 associated lipids
Neoplasms, Hormone-Dependent D009376 23 associated lipids
Cardiovascular Diseases D002318 24 associated lipids
Encephalomyelitis, Autoimmune, Experimental D004681 26 associated lipids
Gastritis D005756 27 associated lipids
Alcoholism D000437 27 associated lipids
Dermatitis D003872 30 associated lipids
Acute Lung Injury D055371 33 associated lipids
Hyperplasia D006965 34 associated lipids
Per page 10 20 50 100 | Total 85

PubChem Associated disorders and diseases

What pathways are associated with gamma-Linolenic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with gamma-Linolenic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with gamma-Linolenic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with gamma-Linolenic acid

Download all related citations
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Authors Title Published Journal PubMed Link
Menendez JA et al. Effect of gamma-linolenic acid on the transcriptional activity of the Her-2/neu (erbB-2) oncogene. 2005 J. Natl. Cancer Inst. pmid:16264182
Das UN Re: Effect of gamma-linolenic acid on the transcriptional activity of the Her-2/neu (erbB-2) oncogene. 2006 J. Natl. Cancer Inst. pmid:16705127
Cunnane SC et al. NMR and isotope ratio mass spectrometry studies of in vivo uptake and metabolism of polyunsaturates by the developing rat brain. 2001 Apr-Jun J. Mol. Neurosci. pmid:11478372
Khongto B et al. Fermentation process development of recombinant Hansenula polymorpha for gamma-linolenic acid production. 2010 J. Microbiol. Biotechnol. pmid:21124062
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Shewale SV et al. Botanical oils enriched in n-6 and n-3 FADS2 products are equally effective in preventing atherosclerosis and fatty liver. 2015 J. Lipid Res. pmid:25921305
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Engler MM et al. Dietary gamma-linolenic acid lowers blood pressure and alters aortic reactivity and cholesterol metabolism in hypertension. 1992 J. Hypertens. pmid:1335001
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Ramandi NF et al. Central composite design for the optimization of supercritical carbon dioxide fluid extraction of fatty acids from Borago officinalis L. flower. 2011 Nov-Dec J. Food Sci. pmid:22416687
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Won J et al. Stability analysis of zinc oxide-nanoencapsulated conjugated linoleic acid and gamma-linolenic acid. 2008 J. Food Sci. pmid:19019122
Garland HO et al. Dietary essential fatty acid supplementation, urinary calcium excretion and reproductive performance in the diabetic pregnant rat. 1997 J. Endocrinol. pmid:9203989
Cheng Z et al. Alteration of prostaglandin production and agonist responsiveness by n-6 polyunsaturated fatty acids in endometrial cells from late-gestation ewes. 2004 J. Endocrinol. pmid:15283685
Braddock R et al. gamma-Linoleic acid and ascorbic acid ameliorate the effects of experimental diabetes on electrolyte and bone homeostasis in pregnant rats. 2002 J. Endocrinol. pmid:12010635
Burnard SL et al. Cilazapril and dietary gamma-linolenic acid prevent the deficit in sciatic nerve conduction velocity in the streptozotocin diabetic rat. 1998 Mar-Apr J. Diabetes Complicat. pmid:9559483
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Kim JJ et al. Properties of cholesterol-reduced butter made with beta-cyclodextrin and added evening primrose oil and phytosterols. 2006 J. Dairy Sci. pmid:17106080
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Furse RK et al. Oral administration of gammalinolenic acid, an unsaturated fatty acid with anti-inflammatory properties, modulates interleukin-1beta production by human monocytes. 2002 J. Clin. Immunol. pmid:11998897
Roemen TH et al. Quantitative assessment of gamma-linolenic acid in human blood and plasma with capillary gas chromatography. 1990 J. Chromatogr. pmid:2166745
Martin TA et al. Synergistic regulation of endothelial tight junctions by antioxidant (Se) and polyunsaturated lipid (GLA) via Claudin-5 modulation. 2006 J. Cell. Biochem. pmid:16514648
Martin TA et al. Enhanced tight junction function in human breast cancer cells by antioxidant, selenium and polyunsaturated lipid. 2007 J. Cell. Biochem. pmid:17243118
Zaitone SA et al. Effect of evening primrose oil and ω-3 polyunsaturated fatty acids on the cardiovascular risk of celecoxib in rats. 2011 J. Cardiovasc. Pharmacol. pmid:21499116
Čertík M et al. Simultaneous enrichment of cereals with polyunsaturated fatty acids and pigments by fungal solid state fermentations. 2013 J. Biotechnol. pmid:23583333
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Burke A et al. Specific analysis in plasma and urine of 2,3-dinor-5, 6-dihydro-isoprostane F(2alpha)-III, a metabolite of isoprostane F(2alpha)-III and an oxidation product of gamma-linolenic acid. 2000 J. Biol. Chem. pmid:10644705
Weaver KL et al. Effect of dietary fatty acids on inflammatory gene expression in healthy humans. 2009 J. Biol. Chem. pmid:19359242
Kawashima Y et al. Peroxisome proliferators enhance linoleic acid metabolism in rat liver. Increased biosynthesis of omega 6 polyunsaturated fatty acids. 1990 J. Biol. Chem. pmid:2160962
MEAD JF and HOWTON DR Metabolism of essential fatty acids. VII. Conversion of gamma-linolenic acid to arachidonic acid. 1957 J. Biol. Chem. pmid:13502321
Muriana FJ et al. Fatty acid composition and properties of the liver microsomal membrane of rats fed diets enriched with cholesterol. 1992 J. Biochem. pmid:1491012
Zhu Y and Zhang BB Molecular cloning and functional characterization of a Δ6-fatty acid desaturase gene from Rhizopus oryzae. 2013 J. Basic Microbiol. pmid:22961300
Laho T et al. Effects of prefermented cereal-derived substrates (ground barley and rye bran) enriched with fungal γ-linolenic acid on rumen fermentation parameters and lipid metabolism in vitro. 2011 J. Appl. Microbiol. pmid:21672096