| MeSH term | MeSH ID | Detail |
|---|---|---|
| Cystic Fibrosis | D003550 | 65 associated lipids |
| Hypertension | D006973 | 115 associated lipids |
| Dermatitis | D003872 | 30 associated lipids |
| Leukemia, Myeloid, Acute | D015470 | 19 associated lipids |
| Neoplasms, Hormone-Dependent | D009376 | 23 associated lipids |
| Dermatitis, Seborrheic | D012628 | 10 associated lipids |
| Hyperlipidemias | D006949 | 73 associated lipids |
| Encephalomyelitis, Autoimmune, Experimental | D004681 | 26 associated lipids |
| Dermatitis, Atopic | D003876 | 19 associated lipids |
| Premenstrual Syndrome | D011293 | 7 associated lipids |
gamma-Linolenic acid
Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.
Cross Reference
Introduction
To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid
PubChem Associated disorders and diseases
What pathways are associated with gamma-Linolenic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with gamma-Linolenic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with gamma-Linolenic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
What genes are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
What common seen animal models are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with gamma-Linolenic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Leaver HA et al. | Intracellular oxidation by human glioma cell populations: effect of arachidonic acid. | 2004 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:15062847 |
| Miles EA et al. | The influence of different combinations of gamma-linolenic, stearidonic and eicosapentaenoic acids on the fatty acid composition of blood lipids and mononuclear cells in human volunteers. | 2004 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:15120716 |
| Torres CF et al. | Lipase-catalyzed ethanolysis of borage oil: a kinetic study. | 2004 May-Jun | Biotechnol. Prog. | pmid:15176879 |
| Gillis RC et al. | Inhibition of 5-lipoxygenase induces cell death in anti-inflammatory fatty acid-treated HL-60 cells. | 2004 Sep-Oct | JPEN J Parenter Enteral Nutr | pmid:15449569 |
| Liu FX et al. | [Study on the encapsulation technique of high purity gamma-linolenic acid, part 1--Single factor, and two-factor tests for encapsulation process]. | 2005 | Zhongguo Zhong Yao Za Zhi | pmid:15810447 |
| Menendez JA et al. | Inhibition of fatty acid synthase-dependent neoplastic lipogenesis as the mechanism of gamma-linolenic acid-induced toxicity to tumor cells: an extension to Nwankwo's hypothesis. | 2005 | Med. Hypotheses | pmid:15607568 |
| Vahedi K et al. | A 3-month double-blind randomised study comparing an olive oil- with a soyabean oil-based intravenous lipid emulsion in home parenteral nutrition patients. | 2005 | Br. J. Nutr. | pmid:16351767 |
| Menendez JA et al. | Effect of gamma-linolenic acid on the transcriptional activity of the Her-2/neu (erbB-2) oncogene. | 2005 | J. Natl. Cancer Inst. | pmid:16264182 |
| Heard CM et al. | Preferential pi-pi complexation between tamoxifen and borage oil/gamma linolenic acid: transcutaneous delivery and NMR spectral modulation. | 2005 | Int J Pharm | pmid:16115741 |
| Efstathopoulos N et al. | N-6 polyunsaturated fatty acids confer hemodynamic stability in an experimental model of multiple trauma. | 2005 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:15850717 |
| Oikawa D et al. | Modification of skin composition by conjugated linoleic acid alone or with combination of other fatty acids in mice. | 2005 | Br. J. Nutr. | pmid:16115363 |
| Vang K and Ziboh VA | 15-lipoxygenase metabolites of gamma-linolenic acid/eicosapentaenoic acid suppress growth and arachidonic acid metabolism in human prostatic adenocarcinoma cells: possible implications of dietary fatty acids. | 2005 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:15850718 |
| Taweechaisupapong S et al. | Evening primrose oil effects on osteoclasts during tooth movement. | 2005 | Angle Orthod | pmid:15898373 |
| Na-Ranong S et al. | Substrate specificity and preference of Delta6-desaturase of Mucor rouxii. | 2005 | FEBS Lett. | pmid:15862319 |
| Cerolini S et al. | Dietary fish and evening primrose oil with vitamin E effects on semen variables in cockerels. | 2005 | Br. Poult. Sci. | pmid:15957443 |
| Hao YL et al. | Cloning of delta6-desaturase from Mucor circinelloides and its high expression in Saccharomyces cerevisiae. | 2005 | Yi Chuan Xue Bao | pmid:15931792 |
| Tahvonen RL et al. | Black currant seed oil and fish oil supplements differ in their effects on fatty acid profiles of plasma lipids, and concentrations of serum total and lipoprotein lipids, plasma glucose and insulin. | 2005 | J. Nutr. Biochem. | pmid:15936647 |
| Seidel A et al. | The Influence of long-chain polyunsaturated fatty acids on total lipid fatty acid composition of a canine mastocytoma cell line. | 2005 | J Vet Med A Physiol Pathol Clin Med | pmid:15943605 |
| Cury-Boaventura MF and Curi R | Regulation of reactive oxygen species (ROS) production by C18 fatty acids in Jurkat and Raji cells. | 2005 | Clin. Sci. | pmid:15563273 |
| Hirasawa A et al. | Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120. | 2005 | Nat. Med. | pmid:15619630 |
| Aragona P et al. | Systemic omega-6 essential fatty acid treatment and pge1 tear content in Sjögren's syndrome patients. | 2005 | Invest. Ophthalmol. Vis. Sci. | pmid:16303936 |
| Takeno S et al. | Molecular evidence that the rate-limiting step for the biosynthesis of arachidonic acid in Mortierella alpina is at the level of an elongase. | 2005 | Lipids | pmid:15825827 |
| Hrastinger A et al. | Is there clinical evidence supporting the use of botanical dietary supplements in children? | 2005 | J. Pediatr. | pmid:15756210 |
| Watkins G et al. | Gamma-Linolenic acid regulates the expression and secretion of SPARC in human cancer cells. | 2005 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:15763439 |
| Qureshi S and Sultan N | Topical nonsteroidal anti-inflammatory drugs versus oil of evening primrose in the treatment of mastalgia. | 2005 | Surgeon | pmid:15789786 |
| Patnayak S and Sree A | Screening of bacterial associates of marine sponges for single cell oil and PUFA. | 2005 | Lett. Appl. Microbiol. | pmid:15836739 |
| Goyal A and Mansel RE | A randomized multicenter study of gamolenic acid (Efamast) with and without antioxidant vitamins and minerals in the management of mastalgia. | 2005 Jan-Feb | Breast J | pmid:15647077 |
| Verhoeven MO et al. | Effect of a combination of isoflavones and Actaea racemosa Linnaeus on climacteric symptoms in healthy symptomatic perimenopausal women: a 12-week randomized, placebo-controlled, double-blind study. | 2005 Jul-Aug | Menopause | pmid:16037756 |
| Guil-Guerrero JL et al. | Gamma-linolenic acid from Cape Verdian Boraginaceae. | 2006 | Nat. Prod. Res. | pmid:16286301 |
| Pontes-Arruda A et al. | Effects of enteral feeding with eicosapentaenoic acid, gamma-linolenic acid, and antioxidants in mechanically ventilated patients with severe sepsis and septic shock. | 2006 | Crit. Care Med. | pmid:16850002 |
| Fakas S et al. | Lipids of Cunninghamella echinulata with emphasis to gamma-linolenic acid distribution among lipid classes. | 2006 | Appl. Microbiol. Biotechnol. | pmid:16850299 |
| Kong X et al. | Induction of apoptosis in K562/ADM cells by gamma-linolenic acid involves lipid peroxidation and activation of caspase-3. | 2006 | Chem. Biol. Interact. | pmid:16857180 |
| Pham H et al. | Dietary gamma-linolenate attenuates tumor growth in a rodent model of prostatic adenocarcinoma via suppression of elevated generation of PGE(2) and 5S-HETE. | 2006 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:16567086 |
| Singer P et al. | Benefit of an enteral diet enriched with eicosapentaenoic acid and gamma-linolenic acid in ventilated patients with acute lung injury. | 2006 | Crit. Care Med. | pmid:16484911 |
| Das UN and Rao KP | Effect of gamma-linolenic acid and prostaglandins E1 on gamma-radiation and chemical-induced genetic damage to the bone marrow cells of mice. | 2006 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:16488586 |
| Martin TA et al. | Synergistic regulation of endothelial tight junctions by antioxidant (Se) and polyunsaturated lipid (GLA) via Claudin-5 modulation. | 2006 | J. Cell. Biochem. | pmid:16514648 |
| Pacht ER | Enteral therapy to decrease morbidity and improve survival in acute respiratory distress syndrome: its time has come. | 2006 | Crit. Care Med. | pmid:16921322 |
| Arab K et al. | Conjugated linoleic acid, unlike other unsaturated fatty acids, strongly induces glutathione synthesis without any lipoperoxidation. | 2006 | Br. J. Nutr. | pmid:17092368 |
| Das UN | Tumoricidal and anti-angiogenic actions of gamma-linolenic acid and its derivatives. | 2006 | Curr Pharm Biotechnol | pmid:17168663 |
| Morse NL and Clough PM | A meta-analysis of randomized, placebo-controlled clinical trials of Efamol evening primrose oil in atopic eczema. Where do we go from here in light of more recent discoveries? | 2006 | Curr Pharm Biotechnol | pmid:17168667 |
| Kapoor R and Huang YS | Gamma linolenic acid: an antiinflammatory omega-6 fatty acid. | 2006 | Curr Pharm Biotechnol | pmid:17168669 |
| DeMichele SJ et al. | A nutritional strategy to improve oxygenation and decrease morbidity in patients who have acute respiratory distress syndrome. | 2006 | Respir Care Clin N Am | pmid:17150431 |
| Kim JJ et al. | Properties of cholesterol-reduced butter made with beta-cyclodextrin and added evening primrose oil and phytosterols. | 2006 | J. Dairy Sci. | pmid:17106080 |
| Gasperino J and Kvetan V | Acute lung injury and nutritional support. | 2006 | Crit. Care Med. | pmid:16550085 |
| Yu Z et al. | Induction of renal cytochrome P450 arachidonic acid epoxygenase activity by dietary gamma-linolenic acid. | 2006 | J. Pharmacol. Exp. Ther. | pmid:16421287 |
| Tocher DR et al. | Effect of diets enriched in Delta6 desaturated fatty acids (18:3n-6 and 18:4n-3), on growth, fatty acid composition and highly unsaturated fatty acid synthesis in two populations of Arctic charr (Salvelinus alpinus L.). | 2006 | Comp. Biochem. Physiol. B, Biochem. Mol. Biol. | pmid:16630735 |
| Kitz R et al. | Impact of early dietary gamma-linolenic acid supplementation on atopic eczema in infancy. | 2006 | Pediatr Allergy Immunol | pmid:16618360 |
| Chen YC et al. | Therapeutic effect of topical gamma-linolenic acid on refractory uremic pruritus. | 2006 | Am. J. Kidney Dis. | pmid:16797388 |
| Miles EA et al. | Self-reported health problems in young male subjects supplementing their diet with oils rich in eicosapentaenoic, gamma-linolenic and stearidonic acids. | 2006 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:16820286 |
| Azevedo-Martins AK et al. | Fatty acid-induced toxicity and neutral lipid accumulation in insulin-producing RINm5F cells. | 2006 | Toxicol In Vitro | pmid:16644178 |