gamma-Linolenic acid

Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.

Cross Reference

Introduction

To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid

MeSH term MeSH ID Detail
Carpal Tunnel Syndrome D002349 3 associated lipids
Back Pain D001416 5 associated lipids
Urolithiasis D052878 1 associated lipids
Mastocytoma D034801 3 associated lipids
Ecchymosis D004438 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with gamma-Linolenic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with gamma-Linolenic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with gamma-Linolenic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with gamma-Linolenic acid

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Authors Title Published Journal PubMed Link
Cameron NE et al. Effects of alpha-lipoic acid on neurovascular function in diabetic rats: interaction with essential fatty acids. 1998 Diabetologia pmid:9562342
Engler MM and Engler MB Dietary borage oil alters plasma, hepatic and vascular tissue fatty acid composition in spontaneously hypertensive rats. 1998 Prostaglandins Leukot. Essent. Fatty Acids pmid:9758202
van Rooyen J et al. Diet can manipulate the metabolism of EPA and GLA in erythrocyte membrane and plasma. 1998 Prostaglandins Leukot. Essent. Fatty Acids pmid:9758205
Tanaka T et al. Methylene-interrupted double bond in polyunsaturated fatty acid is an essential structure for metabolism by the fatty acid chain elongation system of rat liver. 1998 Biochim. Biophys. Acta pmid:9748638
de Vries JE [Painful breasts]. 1998 Ned Tijdschr Geneeskd pmid:9749309
Ravichandran D et al. Effect of lithium gamma-linolenate on the growth of experimental human pancreatic carcinoma. 1998 Br J Surg pmid:9752859
Brouwer DA et al. Gamma-linolenic acid does not augment long-chain polyunsaturated fatty acid omega-3 status. 1998 Prostaglandins Leukot. Essent. Fatty Acids pmid:9888208
Fan YY and Chapkin RS Importance of dietary gamma-linolenic acid in human health and nutrition. 1998 J. Nutr. pmid:9732298
Dirks J et al. Cytokine levels affected by gamma-linolenic acid. 1998 Prostaglandins Leukot. Essent. Fatty Acids pmid:9849654
Leng GC et al. Randomized controlled trial of gamma-linolenic acid and eicosapentaenoic acid in peripheral arterial disease. 1998 Clin Nutr pmid:10205349
Hounsom L et al. A lipoic acid-gamma linolenic acid conjugate is effective against multiple indices of experimental diabetic neuropathy. 1998 Diabetologia pmid:9686927
Kumamoto T and Ide T Comparative effects of alpha- and gamma-linolenic acids on rat liver fatty acid oxidation. 1998 Lipids pmid:9688166
Bell JG et al. Growth, mortality, tissue histopathology and fatty acid compositions, eicosanoid production and response to stress, in juvenile turbot fed diets rich in gamma-linolenic acid in combination with eicosapentaenoic acid or docosahexaenoic acid. 1998 Prostaglandins Leukot. Essent. Fatty Acids pmid:9690713
Ravichandran D et al. Growth inhibitory effect of lithium gammalinolenate on pancreatic cancer cell lines: the influence of albumin and iron. 1998 Eur. J. Cancer pmid:9624256
Sanderson P and Calder PC Dietary fish oil appears to prevent the activation of phospholipase C-gamma in lymphocytes. 1998 Biochim. Biophys. Acta pmid:9630688
Martens-Lobenhoffer J and Meyer FP Pharmacokinetic data of gamma-linolenic acid in healthy volunteers after the administration of evening primrose oil (Epogam). 1998 Int J Clin Pharmacol Ther pmid:9707349
Johnson SR Premenstrual syndrome therapy. 1998 Clin Obstet Gynecol pmid:9646973
Engler MM et al. Effects of dietary gamma-linolenic acid on blood pressure and adrenal angiotensin receptors in hypertensive rats. 1998 Proc. Soc. Exp. Biol. Med. pmid:9648942
Giamarellos-Bourboulis EJ et al. In vitro activity of polyunsaturated fatty acids on Pseudomonas aeruginosa: relationship to lipid peroxidation. 1998 Prostaglandins Leukot. Essent. Fatty Acids pmid:9654401
Kahler CP and Du Plooy WJ Effect of gammalinolenic acid, dihomogammalinolenic acid, ascorbyl-6-gammalinolenic acid, and ascorbyl-6-dihomo gammalinolenic acid on histamine- and methacholine-induced contraction of the isolated guinea pig tracheal chain. 1998 Prostaglandins Leukot. Essent. Fatty Acids pmid:9654407
Solomon LZ et al. Bladder cancer recurrence by implantation of exfoliated cells: is gamma-linolenic acid an effective tumoricidal agent? 1998 Br J Urol pmid:9698674
Vartak S et al. Gamma-linolenic acid (GLA) is cytotoxic to 36B10 malignant rat astrocytoma cells but not to 'normal' rat astrocytes. 1998 Br. J. Cancer pmid:9635836
McGahon B et al. Analysis of the effect of membrane arachidonic acid concentration on modulation of glutamate release by interleukin-1: an age-related study. 1998 Exp. Gerontol. pmid:9639170
Reilly JD et al. Effect of a supplementary dietary evening primrose oil mixture on hoof growth, hoof growth rate and hoof lipid fractions in horses: a controlled and blinded trial. 1998 Equine Vet J Suppl pmid:9932095
Kruger MC et al. Calcium, gamma-linolenic acid and eicosapentaenoic acid supplementation in senile osteoporosis. 1998 Aging (Milano) pmid:9932142
Ramesh G and Das UN Effect of evening primrose and fish oils on two stage skin carcinogenesis in mice. 1998 Prostaglandins Leukot. Essent. Fatty Acids pmid:9844986
Kuruvilla R et al. Evening primrose oil treatment corrects reduced conduction velocity but not depletion of arachidonic acid in nerve from streptozotocin-induced diabetic rats. 1998 Prostaglandins Leukot. Essent. Fatty Acids pmid:9844993
Schellhammer PF Intravesical chemotherapy with gamma linolenic acid becomes a reality. 1998 J. Urol. pmid:9817299
Solomon LZ et al. Intravesical chemotherapy with gamma linolenic acid becomes a realistic prospect in serum-free applications: in vitro cytotoxicity and systemic absorption studies. 1998 J. Urol. pmid:9817384
Marra F et al. Effects of supplementation with unsaturated fatty acids on plasma and membrane lipid composition and platelet function in patients with cirrhosis and defective aggregation. 1998 J. Hepatol. pmid:9566835
Chen Q et al. Analysis of the acyl-CoAs that accumulate during the peroxisomal beta-oxidation of arachidonic acid and 6,9,12-octadecatrienoic acid. 1998 Arch. Biochem. Biophys. pmid:9448727
Ramesh G and Das UN Effect of cis-unsaturated fatty acids on Meth-A ascitic tumour cells in vitro and in vivo. 1998 Cancer Lett. pmid:9489490
Jiang WG et al. Regulation of tight junction permeability and occludin expression by polyunsaturated fatty acids. 1998 Biochem. Biophys. Res. Commun. pmid:9514943
Kairemo KJ et al. The effect of lithium gamma-linolenate therapy of pancreatic cancer on perfusion in liver and pancreatic tissues. 1998 Pancreas pmid:9436871
Kairemo KJ et al. Effects of lithium gammalinolenate on the perfusion of liver and pancreatic tissues in pancreatic cancer. 1997 Sep-Oct Anticancer Res. pmid:9427770
Andreassi M et al. Efficacy of gamma-linolenic acid in the treatment of patients with atopic dermatitis. 1997 Sep-Oct J. Int. Med. Res. pmid:9364289
Tollesson A et al. Malassezia furfur in infantile seborrheic dermatitis. 1997 Nov-Dec Pediatr Dermatol pmid:9436835
Borrek S et al. [Gamma-linolenic-acid-rich borage seed oil capsules in children with atopic dermatitis. A placebo-controlled double-blind study]. 1997 May-Jun Klin Padiatr pmid:9244815
Palombo JD et al. Cyclic vs continuous enteral feeding with omega-3 and gamma-linolenic fatty acids: effects on modulation of phospholipid fatty acids in rat lung and liver immune cells. 1997 May-Jun JPEN J Parenter Enteral Nutr pmid:9168366
Morris GM et al. Modulation of the cell kinetics of pig skin by the topical application of evening primrose oil or Lioxasol. 1997 Aug-Sep Cell Prolif. pmid:9501921
Bordoni A et al. Manipulation of lipid composition of rat heart myocytes aged in culture and its effect on alpha1-adrenoceptor stimulation. 1997 Biochim. Biophys. Acta pmid:9366250
Larsen LN et al. Polyunsaturated thia- and oxa-fatty acids: incorporation into cell-lipids and their effects on arachidonic acid- and eicosanoid synthesis. 1997 Biochim. Biophys. Acta pmid:9366251
Ziboh VA et al. gamma-Linolenic acid-containing diet attenuates bleomycin-induced lung fibrosis in hamsters. 1997 Lipids pmid:9252965
De La Cruz JP et al. Effect of evening primrose oil on platelet aggregation in rabbits fed an atherogenic diet. 1997 Thromb. Res. pmid:9253809
Fang C et al. Expression of constitutive cyclo-oxygenase (COX-1) in rats with streptozotocin-induced diabetes; effects of treatment with evening primrose oil or an aldose reductase inhibitor on COX-1 mRNA levels. 1997 Prostaglandins Leukot. Essent. Fatty Acids pmid:9051726
McGahon B et al. The ability of aged rats to sustain long-term potentiation is restored when the age-related decrease in membrane arachidonic acid concentration is reversed. 1997 Neuroscience pmid:9300396
Quoc KP and Dubacq JP Effect of growth temperature on the biosynthesis of eukaryotic lipid molecular species by the cyanobacterium Spirulina platensis. 1997 Biochim. Biophys. Acta pmid:9219908
Purasiri P et al. Modulation in vitro of human natural cytotoxicity, lymphocyte proliferative response to mitogens and cytokine production by essential fatty acids. 1997 Immunology pmid:9415022
de Antueno R et al. In vivo and in vitro biotransformation of the lithium salt of gamma-linolenic acid by three human carcinomas. 1997 Br. J. Cancer pmid:9192987
Griffiths G et al. Effect of n-6 polyunsaturated fatty acids on growth and lipid composition of neoplastic and non-neoplastic canine prostate epithelial cell cultures. 1997 Prostate pmid:9108883