gamma-Linolenic acid

Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.

Cross Reference

Introduction

To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid

MeSH term MeSH ID Detail
Cystic Fibrosis D003550 65 associated lipids
Hypertension D006973 115 associated lipids
Dermatitis D003872 30 associated lipids
Leukemia, Myeloid, Acute D015470 19 associated lipids
Neoplasms, Hormone-Dependent D009376 23 associated lipids
Dermatitis, Seborrheic D012628 10 associated lipids
Hyperlipidemias D006949 73 associated lipids
Encephalomyelitis, Autoimmune, Experimental D004681 26 associated lipids
Dermatitis, Atopic D003876 19 associated lipids
Premenstrual Syndrome D011293 7 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with gamma-Linolenic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with gamma-Linolenic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with gamma-Linolenic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with gamma-Linolenic acid

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Authors Title Published Journal PubMed Link
Fuller MA et al. Activity of soybean lipoxygenase isoforms against esterified fatty acids indicates functional specificity. 2001 Arch. Biochem. Biophys. pmid:11361131
Kamphuis MM et al. Fat-specific satiety in humans for fat high in linoleic acid vs fat high in oleic acid. 2001 Eur J Clin Nutr pmid:11423927
Chakrabarti KB et al. Modification of doxorubicin-induced cardiotoxicity: effect of essential fatty acids and ICRF-187 (dexrazoxane). 2001 Eur. J. Cancer pmid:11435077
Banni S et al. Vaccenic acid feeding increases tissue levels of conjugated linoleic acid and suppresses development of premalignant lesions in rat mammary gland. 2001 Nutr Cancer pmid:12094634
Olguín EJ et al. The effect of low light flux and nitrogen deficiency on the chemical composition of Spirulina sp. (Arthrospira) grown on digested pig waste. 2001 Bioresour. Technol. pmid:11211071
Hounsom L et al. Oxidative stress participates in the breakdown of neuronal phenotype in experimental diabetic neuropathy. 2001 Diabetologia pmid:11357471
Goffman FD and Galletti S Gamma-linolenic acid and tocopherol contents in the seed oil of 47 accessions from several Ribes species. 2001 J. Agric. Food Chem. pmid:11170598
Conti E et al. gamma-Linolenic acid production by solid-state fermentation of Mucorales strains on cereals. 2001 Bioresour. Technol. pmid:11198184
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Biessels GJ et al. The effect of gamma-linolenic acid-alpha-lipoic acid on functional deficits in the peripheral and central nervous system of streptozotocin-diabetic rats. 2001 J. Neurol. Sci. pmid:11137514
Wollheim FA [Meager support for herbal therapy of rheumatoid arthritis]. 2001 Lakartidningen pmid:11699249
Kast RE Borage oil reduction of rheumatoid arthritis activity may be mediated by increased cAMP that suppresses tumor necrosis factor-alpha. 2001 Int. Immunopharmacol. pmid:11710548
Ide T et al. Dietary mold oil rich in gamma linolenic acid increases insulin-dependent glucose utilization in isolated rat adipocytes. 2001 Comp. Biochem. Physiol. B, Biochem. Mol. Biol. pmid:11567903
Kaku S et al. Dietary gamma-linolenic acid dose-dependently modifies fatty acid composition and immune parameters in rats. 2001 Prostaglandins Leukot. Essent. Fatty Acids pmid:11728173
Colquhoun A and Schumacher RI gamma-Linolenic acid and eicosapentaenoic acid induce modifications in mitochondrial metabolism, reactive oxygen species generation, lipid peroxidation and apoptosis in Walker 256 rat carcinosarcoma cells. 2001 Biochim. Biophys. Acta pmid:11731331
Birch AE et al. Antioxidant properties of evening primrose seed extracts. 2001 J. Agric. Food Chem. pmid:11559161
Demmelmair H et al. Influence of formulas with borage oil or borage oil plus fish oil on the arachidonic acid status in premature infants. 2001 Lipids pmid:11485158
Guil-Guerrero JL et al. Occurrence and characterization of oils rich in gamma-linolenic acid (III): the taxonomical value of the fatty acids in Echium (Boraginaceae). 2001 Phytochemistry pmid:11524120
Ford I et al. The effects of treatment with alpha-lipoic acid or evening primrose oil on vascular hemostatic and lipid risk factors, blood flow, and peripheral nerve conduction in the streptozotocin-diabetic rat. 2001 Metab. Clin. Exp. pmid:11474472
Tsimaratos M et al. Gamma-linolenic acid restores renal medullary thick ascending limb Na(+),K(+)-ATPase activity in diabetic rats. 2001 J. Nutr. pmid:11739860
Thies F et al. Influence of dietary supplementation with long-chain n-3 or n-6 polyunsaturated fatty acids on blood inflammatory cell populations and functions and on plasma soluble adhesion molecules in healthy adults. 2001 Lipids pmid:11795850
Kaku S et al. Interactions of dietary fats and proteins on fatty acid composition of immune cells and LTB4 production by peritoneal exudate cells of rats. 2001 Biosci. Biotechnol. Biochem. pmid:11302164
Sims EC and Plowman PN Stereotactic radiosurgery XII. Large AVM and the failure of the radiation response modifier gamma linolenic acid to improve the therapeutic ratio. 2001 Br J Neurosurg pmid:11303657
Nwankwo JO Repression of cellular anaplerosis as the hypothesized mechanism of gamma-linolenic acid-induced toxicity to tumor cells. 2001 Med. Hypotheses pmid:11388772
Furse RK et al. Gammalinolenic acid, an unsaturated fatty acid with anti-inflammatory properties, blocks amplification of IL-1 beta production by human monocytes. 2001 J. Immunol. pmid:11418687
Thies F et al. Dietary supplementation with gamma-linolenic acid or fish oil decreases T lymphocyte proliferation in healthy older humans. 2001 J. Nutr. pmid:11435508
Yogo Y and Fujishima S [Nutritional support for ARDS]. 2001 Nippon Rinsho pmid:11439576
Frenoux JM et al. A polyunsaturated fatty acid diet lowers blood pressure and improves antioxidant status in spontaneously hypertensive rats. 2001 J. Nutr. pmid:11208936
Cunnane SC et al. NMR and isotope ratio mass spectrometry studies of in vivo uptake and metabolism of polyunsaturates by the developing rat brain. 2001 Apr-Jun J. Mol. Neurosci. pmid:11478372
Nwankwo JO and Robbins ME Peroxisome proliferator-activated receptor- gamma expression in human malignant and normal brain, breast and prostate-derived cells. 2001 Apr-May Prostaglandins Leukot. Essent. Fatty Acids pmid:11418018
Borenshtein D et al. Cataract development in diabetic sand rats treated with alpha-lipoic acid and its gamma-linolenic acid conjugate. 2001 Jan-Feb Diabetes Metab. Res. Rev. pmid:11241890
Zavodnik LB et al. [Effect of gamma-linolenic acid on microsomal oxidation in the rat liver following gamma-irradiation]. 2001 Jul-Aug Eksp Klin Farmakol pmid:11589114
OtleÅŸ S and Pire R Fatty acid composition of Chlorella and Spirulina microalgae species. 2001 Nov-Dec J AOAC Int pmid:11767135
Keegan A et al. Corpus cavernosum dysfunction in diabetic rats: effects of combined alpha-lipoic acid and gamma-linolenic acid treatment. 2001 Sep-Oct Diabetes Metab. Res. Rev. pmid:11747143
Simoncíkova P et al. Comparison of the extrapancreatic action of gamma-linolenic acid and n-3 PUFAs in the high fat diet-induced insulin resistance [corrected]. 2002 Endocr Regul pmid:12466014
Leaver HA et al. Highly unsaturated fatty acid induced tumour regression in glioma pharmacodynamics and bioavailability of gamma linolenic acid in an implantation glioma model: effects on tumour biomass, apoptosis and neuronal tissue histology. 2002 Prostaglandins Leukot. Essent. Fatty Acids pmid:12445487
Blommers J et al. Evening primrose oil and fish oil for severe chronic mastalgia: a randomized, double-blind, controlled trial. 2002 Am. J. Obstet. Gynecol. pmid:12439536
Senanayake SP and Shahidi F Positional distribution of FA in TAG of enzymatically modified borage and evening primrose oils. 2002 Lipids pmid:12371752
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Dyer O Doctor accused of giving false information to drug trial. 2002 BMJ pmid:12269314
Cook D et al. Modification of fatty acid composition in tomato (Lycopersicon esculentum) by expression of a borage delta6-desaturase. 2002 Mol. Biotechnol. pmid:12059112
Leaver HA et al. Antitumour and pro-apoptotic actions of highly unsaturated fatty acids in glioma. 2002 Prostaglandins Leukot. Essent. Fatty Acids pmid:12051954
Chung S et al. Gamma-linolenic acid in borage oil reverses epidermal hyperproliferation in guinea pigs. 2002 J. Nutr. pmid:12368400
Gillis RC et al. Eicosapentaenoic acid and gamma-linolenic acid induce apoptosis in HL-60 cells. 2002 J. Surg. Res. pmid:12384078
Pérez Y et al. Measurement by nuclear magnetic resonance diffusion of the dimensions of the mobile lipid compartment in C6 cells. 2002 Cancer Res. pmid:12384523
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Uesaka Y [Prevention and treatment of diabetic neuropathy]. 2002 Nippon Rinsho pmid:12430238
Hamburger M et al. Constituents in evening primrose oil with radical scavenging, cyclooxygenase, and neutrophil elastase inhibitory activities. 2002 J. Agric. Food Chem. pmid:12236675
Khunyoshyeng S et al. Differential expression of desaturases and changes in fatty acid composition during sporangiospore germination and development in Mucor rouxii. 2002 Fungal Genet. Biol. pmid:12223185
Whelan J et al. Dietary EPA reduces tumor load in ApcMin/+ mice by altering arachidonic acid metabolism, but conjugated linoleic acid, gamma--and alpha-linolenic acids have no effect. 2002 Adv. Exp. Med. Biol. pmid:12664643