gamma-Linolenic acid

Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.

Cross Reference

Introduction

To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid

MeSH term MeSH ID Detail
Neoplasm Invasiveness D009361 23 associated lipids
Neoplasms, Hormone-Dependent D009376 23 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Neuroblastoma D009447 66 associated lipids
Pain D010146 64 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Pityriasis D010915 3 associated lipids
Premenstrual Syndrome D011293 7 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Psoriasis D011565 47 associated lipids
Per page 10 20 50 100 | Total 85

PubChem Associated disorders and diseases

What pathways are associated with gamma-Linolenic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with gamma-Linolenic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with gamma-Linolenic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with gamma-Linolenic acid

Download all related citations
Per page 10 20 50 100 | Total 1121
Authors Title Published Journal PubMed Link
Williams WV et al. Effects of unsaturated fatty acids on expression of early response genes in human T lymphocytes. 1996 Pathobiology pmid:8856792
Deferne JL and Leeds AR Resting blood pressure and cardiovascular reactivity to mental arithmetic in mild hypertensive males supplemented with blackcurrant seed oil. 1996 J Hum Hypertens pmid:8895037
Papanikolaou N et al. Effects of OKY-046 and nifedipine in cyclosporine-induced renal dysfunction in rats. 1996 Prostaglandins Leukot. Essent. Fatty Acids pmid:8951993
Matsuo N et al. Effects of gamma-linolenic acid and its positional isomer pinolenic acid on immune parameters of brown-Norway rats. 1996 Prostaglandins Leukot. Essent. Fatty Acids pmid:8951990
Hederos CA and Berg A Epogam evening primrose oil treatment in atopic dermatitis and asthma. 1996 Arch. Dis. Child. pmid:9014601
Glen AI et al. Membrane fatty acids, niacin flushing and clinical parameters. 1996 Prostaglandins Leukot. Essent. Fatty Acids pmid:8888117
Cameron NE and Cotter MA Comparison of the effects of ascorbyl gamma-linolenic acid and gamma-linolenic acid in the correction of neurovascular deficits in diabetic rats. 1996 Diabetologia pmid:8877288
Awad AB et al. The effect of unsaturated fatty acids on membrane composition and signal transduction in HT-29 human colon cancer cells. 1996 Cancer Lett. pmid:8950205
Reddy AS and Thomas TL Expression of a cyanobacterial delta 6-desaturase gene results in gamma-linolenic acid production in transgenic plants. 1996 Nat. Biotechnol. pmid:9630958
Sadi AM et al. Dietary effects of corn oil, oleic acid, perilla oil, and evening [corrected] primrose oil on plasma and hepatic lipid level and atherosclerosis in Japanese quail. 1996 Exp. Anim. pmid:8689581
Huang Z et al. Functional identification of the active-site nucleophile of the human 85-kDa cytosolic phospholipase A2. 1996 Biochemistry pmid:8619991
Leaver HA et al. Arachidonic acid activation of monocyte and neutrophil reactive oxygen in lung cancer patients undergoing pulmonary resection. 1996 Biologicals pmid:9088546
Cantrill RC et al. Exogenous gamma-linolenic acid alters hormone stimulated cyclic AMP levels in U937 cells. 1996 Cancer Lett. pmid:8620439
Wainwright PE et al. Effects of dietary gamma-linolenic acid and prenatal ethanol on mouse brain and behavior. 1996 Pharmacol. Biochem. Behav. pmid:8801587
Quoc KP and Pascaud M Effects of dietary gamma-linolenic acid on the tissue phospholipid fatty acid composition and the synthesis of eicosanoids in rats. 1996 Ann. Nutr. Metab. pmid:8773734
Hrelia S et al. gamma-Linolenic acid supplementation can affect cancer cell proliferation via modification of fatty acid composition. 1996 Biochem. Biophys. Res. Commun. pmid:8753781
Fan YY et al. Dietary lipid source alters murine macrophage/vascular smooth muscle cell interactions in vitro. 1996 J. Nutr. pmid:8814195
Omawari N et al. Deficient nitric oxide responsible for reduced nerve blood flow in diabetic rats: effects of L-NAME, L-arginine, sodium nitroprusside and evening primrose oil. 1996 Br. J. Pharmacol. pmid:8733594
Sherrington EJ et al. The effect of dietary lipid manipulation on the uptake of [3H]-triolein by tissues of the rat. 1996 Biochem. Soc. Trans. pmid:8736833
Grant D et al. The antioxidant activity of heparins. 1996 Biochem. Soc. Trans. pmid:8736852
Stainforth JM et al. Clinical aspects of the use of gamma linolenic acid in systemic sclerosis. 1996 Acta Derm. Venereol. pmid:8740271
Budeiri D et al. Is evening primrose oil of value in the treatment of premenstrual syndrome? 1996 Control Clin Trials pmid:8721802
Each of the following has been shown to be effective for cyclical breast pain. 1996 Can Fam Physician pmid:8704485
Schöpf E et al. [Gamma-linolenic acid in atopic patients?]. 1996 Med Monatsschr Pharm pmid:8684312
Jiang WG et al. Inhibition of neutrophil respiratory burst and cytokine priming by gamma-linolenic acid. 1996 Br J Surg pmid:8689213
McCarty MF Fish oil may impede tumour angiogenesis and invasiveness by down-regulating protein kinase C and modulating eicosanoid production. 1996 Med. Hypotheses pmid:8692033
Chilton-Lopez ME et al. Metabolism of gammalinolenic acid in human neutrophils. 1996 J. Immunol. pmid:8609415
Luthria DL and Sprecher H Metabolism of deuterium-labeled linoleic, 6,9,12-octadecatrienoic, 8,11,14-eicosatrienoic, and arachidonic acids in the rat. 1995 J. Lipid Res. pmid:8558078
Berth-Jones J et al. Evening primrose oil and atopic eczema. 1995 Lancet pmid:7861894
Morris GM et al. Trophic effects of essential fatty acids on pig skin. 1995 Cell Prolif. pmid:7893841
Scholey JW and Mills DE Dietary fatty acids and the glomerular hemodynamic response to cyclosporine in borderline hypertensive rats. 1995 Kidney Int. pmid:7723248
Fan YY et al. Dietary gamma-linolenic acid modulates macrophage-vascular smooth muscle cell interactions. Evidence for a macrophage-derived soluble factor that downregulates DNA synthesis in smooth muscle cells. 1995 Arterioscler. Thromb. Vasc. Biol. pmid:7670954
Sherrington EJ et al. The effect of dietary lipid manipulation on macrophage cell surface molecule expression. 1995 Biochem. Soc. Trans. pmid:7672298
Karasu C et al. Effects of anti-oxidant treatment on sciatic nerve dysfunction in streptozotocin-diabetic rats; comparison with essential fatty acids. 1995 Diabetologia pmid:7713308
Dines KC et al. Comparison of the effects of evening primrose oil and triglycerides containing gamma-linolenic acid on nerve conduction and blood flow in diabetic rats. 1995 J. Pharmacol. Exp. Ther. pmid:7714803
Murray MJ et al. Select dietary fatty acids attenuate cardiopulmonary dysfunction during acute lung injury in pigs. 1995 Am. J. Physiol. pmid:8594921
Bell JG et al. Diets rich in eicosapentaenoic acid and gamma-linolenic acid affect phospholipid fatty acid composition and production of prostaglandins E1, E2 and E3 in turbot (Scophthalmus maximus), a species deficient in delta 5 fatty acid desaturase. 1995 Prostaglandins Leukot. Essent. Fatty Acids pmid:8577782
Rothman D et al. Botanical lipids: effects on inflammation, immune responses, and rheumatoid arthritis. 1995 Semin. Arthritis Rheum. pmid:8578315
Dines CD et al. Nerve function in galactosaemic rats: effects of evening primrose oil and doxazosin. 1995 Eur. J. Pharmacol. pmid:8521914
de Bravo MG et al. [Effect of dietary supplementation with gamma-linolenic acid on the growth of a human lung carcinoma implanted in nude mice]. 1995 Medicina (B Aires) pmid:8731577
Giamarellos-Bourboulis EJ et al. In-vitro inhibitory activity of gamma-linolenic acid on Escherichia coli strains and its influence on their susceptibilities to various antimicrobial agents. 1995 J. Antimicrob. Chemother. pmid:8522462
Burgess NA et al. Evaluation of four animal models of intrarenal calcium deposition and assessment of the influence of dietary supplementation with essential fatty acids on calcification. 1995 Urol. Res. pmid:8533210
Harbige LS et al. Prevention of experimental autoimmune encephalomyelitis in Lewis rats by a novel fungal source of gamma-linolenic acid. 1995 Br. J. Nutr. pmid:8541276
Sture GH and Lloyd DH Canine atopic disease: therapeutic use of an evening primrose oil and fish oil combination. 1995 Vet. Rec. pmid:8553525
Cartwright-Shamoon JM et al. A complex biochemical modulation of intestinal ion transport in rats fed on high-fat diets. 1995 J. Pediatr. Gastroenterol. Nutr. pmid:7884616
Karikó K et al. Stimulatory effect of unsaturated fatty acids on the level of plasminogen activator inhibitor-1 mRNA in cultured human endothelial cells. 1995 FEBS Lett. pmid:7890029
Lindskov R and Petersen CS [Oral gamma-linoleic acid (Epogam) in the treatment of atopic dermatitis]. 1995 Ugeskr. Laeg. pmid:7483071
Hrelia S et al. Essential fatty acid metabolism in cultured rat cardiomyocytes in response to either N-6 or N-3 fatty acid supplementation. 1995 Biochem. Biophys. Res. Commun. pmid:7488075
Jiang WG et al. Inhibition of hepatocyte growth factor-induced motility and in vitro invasion of human colon cancer cells by gamma-linolenic acid. 1995 Br. J. Cancer pmid:7710939
Jiang WG et al. Regulation of the expression of E-cadherin on human cancer cells by gamma-linolenic acid (GLA). 1995 Cancer Res. pmid:7585549