gamma-Linolenic acid

Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.

Cross Reference

Introduction

To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid

MeSH term MeSH ID Detail
Scleroderma, Systemic D012595 16 associated lipids
Raynaud Disease D011928 7 associated lipids
Food Hypersensitivity D005512 7 associated lipids
Carcinoma 256, Walker D002279 22 associated lipids
Dysmenorrhea D004412 9 associated lipids
Dyskinesia, Drug-Induced D004409 15 associated lipids
Ascorbic Acid Deficiency D001206 9 associated lipids
Synovitis D013585 15 associated lipids
Arthritis, Psoriatic D015535 3 associated lipids
Atherosclerosis D050197 85 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with gamma-Linolenic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with gamma-Linolenic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with gamma-Linolenic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with gamma-Linolenic acid

Download all related citations
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Authors Title Published Journal PubMed Link
Leaver HA et al. Highly unsaturated fatty acid induced tumour regression in glioma pharmacodynamics and bioavailability of gamma linolenic acid in an implantation glioma model: effects on tumour biomass, apoptosis and neuronal tissue histology. 2002 Prostaglandins Leukot. Essent. Fatty Acids pmid:12445487
Vaddadi KS Use of gamma-linolenic acid in the treatment of schizophrenia and tardive dyskinesia. 1992 Prostaglandins Leukot. Essent. Fatty Acids pmid:1321448
Horrobin DF The relationship between schizophrenia and essential fatty acid and eicosanoid metabolism. 1992 Prostaglandins Leukot. Essent. Fatty Acids pmid:1321449
Fokkema MR et al. Short-term supplementation of low-dose gamma-linolenic acid (GLA), alpha-linolenic acid (ALA), or GLA plus ALA does not augment LCP omega 3 status of Dutch vegans to an appreciable extent. 2000 Prostaglandins Leukot. Essent. Fatty Acids pmid:11090255
Dines KC et al. Effectiveness of natural oils as sources of gamma-linolenic acid to correct peripheral nerve conduction velocity abnormalities in diabetic rats: modulation by thromboxane A2 inhibition. 1996 Prostaglandins Leukot. Essent. Fatty Acids pmid:8931113
Fang C et al. Expression of constitutive cyclo-oxygenase (COX-1) in rats with streptozotocin-induced diabetes; effects of treatment with evening primrose oil or an aldose reductase inhibitor on COX-1 mRNA levels. 1997 Prostaglandins Leukot. Essent. Fatty Acids pmid:9051726
Miles EA et al. Self-reported health problems in young male subjects supplementing their diet with oils rich in eicosapentaenoic, gamma-linolenic and stearidonic acids. 2006 Prostaglandins Leukot. Essent. Fatty Acids pmid:16820286
Engler MM and Engler MB Dietary borage oil alters plasma, hepatic and vascular tissue fatty acid composition in spontaneously hypertensive rats. 1998 Prostaglandins Leukot. Essent. Fatty Acids pmid:9758202
van Rooyen J et al. Diet can manipulate the metabolism of EPA and GLA in erythrocyte membrane and plasma. 1998 Prostaglandins Leukot. Essent. Fatty Acids pmid:9758205
Gardiner NS and Duncan JR Possible involvement of delta-6-desaturase in control of melanoma growth by gamma-linolenic acid. 1991 Prostaglandins Leukot. Essent. Fatty Acids pmid:1650000
Dirks J et al. Cytokine levels affected by gamma-linolenic acid. 1998 Prostaglandins Leukot. Essent. Fatty Acids pmid:9849654
Seegers JC et al. Comparative anti-mitotic effects of lithium gamma-linolenate, gamma-linolenic acid and arachidonic acid, on transformed and embryonic cells. 1998 Prostaglandins Leukot. Essent. Fatty Acids pmid:9849656
Morphake P et al. Alteration of cyclosporine (CsA)-induced nephrotoxicity by gamma linolenic acid (GLA) and eicosapentaenoic acid (EPA) in Wistar rats. 1994 Prostaglandins Leukot. Essent. Fatty Acids pmid:8146206
Cai J et al. Inhibition of angiogenic factor- and tumour-induced angiogenesis by gamma linolenic acid. 1999 Prostaglandins Leukot. Essent. Fatty Acids pmid:10319914
Engler MM Comparative study of diets enriched with evening primrose, black currant, borage or fungal oils on blood pressure and pressor responses in spontaneously hypertensive rats. 1993 Prostaglandins Leukot. Essent. Fatty Acids pmid:8259378
Kahler CP and Du Plooy WJ Effect of gammalinolenic acid, dihomogammalinolenic acid, ascorbyl-6-gammalinolenic acid, and ascorbyl-6-dihomo gammalinolenic acid on histamine- and methacholine-induced contraction of the isolated guinea pig tracheal chain. 1998 Prostaglandins Leukot. Essent. Fatty Acids pmid:9654407
Moodley J and Norman RJ Attempts at dietary alteration of prostaglandin pathways in the management of pre-eclampsia. 1989 Prostaglandins Leukot. Essent. Fatty Acids pmid:2608693
Peterson LD et al. Dose-dependent effects of dietary gamma-linolenic acid on rat spleen lymphocyte functions. 1999 Prostaglandins Leukot. Essent. Fatty Acids pmid:10477037
Griffiths G et al. Effect of n-6 polyunsaturated fatty acids on growth and lipid composition of neoplastic and non-neoplastic canine prostate epithelial cell cultures. 1997 Prostate pmid:9108883
Dobryniewski J et al. [The gamma-linolenic acid (GLA)--the therapeutic value]. 2007 Prz. Lek. pmid:17892041