gamma-Linolenic acid

Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.

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Introduction

To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid

MeSH term MeSH ID Detail
Pityriasis D010915 3 associated lipids
Xerostomia D014987 6 associated lipids
Fallopian Tube Neoplasms D005185 1 associated lipids
Carcinoma, Mucoepidermoid D018277 3 associated lipids
Scurvy D012614 2 associated lipids
Hand Dermatoses D006229 5 associated lipids
Mucocele D009078 1 associated lipids
Salivary Gland Diseases D012466 1 associated lipids
Gastritis, Atrophic D005757 4 associated lipids
Postoperative Hemorrhage D019106 7 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with gamma-Linolenic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with gamma-Linolenic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with gamma-Linolenic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with gamma-Linolenic acid

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Authors Title Published Journal PubMed Link
Turon F et al. A direct method for regiospecific analysis of TAG using alpha-MAG. 2002 Lipids pmid:12371754
Dyer O Doctor accused of giving false information to drug trial. 2002 BMJ pmid:12269314
Tso P et al. Intestinal absorption and lymphatic transport of a high gamma-linolenic acid canola oil in lymph fistula Sprague-Dawley rats. 2002 J. Nutr. pmid:11823581
Deng X et al. Regulation of the rat SREBP-1c promoter in primary rat hepatocytes. 2002 Biochem. Biophys. Res. Commun. pmid:11779162
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Harris NM et al. Intravesical meglumine gamma-linolenic acid in superficial bladder cancer: an efficacy study. 2002 Eur. Urol. pmid:12121728
Hornych A et al. The effect of gamma-linolenic acid on plasma and membrane lipids and renal prostaglandin synthesis in older subjects. 2002 Bratisl Lek Listy pmid:12190041
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Hong H et al. High-level production of gamma-linolenic acid in Brassica juncea using a delta6 desaturase from Pythium irregulare. 2002 Plant Physiol. pmid:12011365
Patel GK and Logan RA Golden nail pigmentation. 2002 J Dermatolog Treat pmid:12006139
Leigh-Firbank EC et al. Eicosapentaenoic acid and docosahexaenoic acid from fish oils: differential associations with lipid responses. 2002 Br. J. Nutr. pmid:12010583
Braddock R et al. gamma-Linoleic acid and ascorbic acid ameliorate the effects of experimental diabetes on electrolyte and bone homeostasis in pregnant rats. 2002 J. Endocrinol. pmid:12010635
Uesaka Y [Prevention and treatment of diabetic neuropathy]. 2002 Nippon Rinsho pmid:12430238
Hamburger M et al. Constituents in evening primrose oil with radical scavenging, cyclooxygenase, and neutrophil elastase inhibitory activities. 2002 J. Agric. Food Chem. pmid:12236675
Khunyoshyeng S et al. Differential expression of desaturases and changes in fatty acid composition during sporangiospore germination and development in Mucor rouxii. 2002 Fungal Genet. Biol. pmid:12223185
Whelan J et al. Dietary EPA reduces tumor load in ApcMin/+ mice by altering arachidonic acid metabolism, but conjugated linoleic acid, gamma--and alpha-linolenic acids have no effect. 2002 Adv. Exp. Med. Biol. pmid:12664643
Pham H and Ziboh VA 5 alpha-reductase-catalyzed conversion of testosterone to dihydrotestosterone is increased in prostatic adenocarcinoma cells: suppression by 15-lipoxygenase metabolites of gamma-linolenic and eicosapentaenoic acids. 2002 J. Steroid Biochem. Mol. Biol. pmid:12589947
Yoon S et al. The therapeutic effect of evening primrose oil in atopic dermatitis patients with dry scaly skin lesions is associated with the normalization of serum gamma-interferon levels. 2002 Jan-Feb Skin Pharmacol. Appl. Skin Physiol. pmid:11803254
Das UN Abrupt and complete occlusion of tumor-feeding vessels by gamma-linolenic acid. 2002 Jul-Aug Nutrition pmid:12093450
Funtikova NS et al. [Synthesis of biologically active lipids by fungus Mucor lusitanicus 306D grown on media with various composition]. 2002 Nov-Dec Prikl. Biokhim. Mikrobiol. pmid:12449793
Harris NM et al. Epirubicin and meglumine gamma-linolenic acid: a logical choice of combination therapy for patients with superficial bladder carcinoma. 2003 Cancer pmid:12491507
Pham H et al. Activation of peroxisome proliferator-activated receptor (PPAR)-gamma by 15S-hydroxyeicosatrienoic acid parallels growth suppression of androgen-dependent prostatic adenocarcinoma cells. 2003 Cancer Lett. pmid:12445673
Shotton HR et al. The effectiveness of treatments of diabetic autonomic neuropathy is not the same in autonomic nerves supplying different organs. 2003 Diabetes pmid:12502507
Delmonte P et al. Synthesis and isolation of trans-7,cis-9 octadecadienoic acid and other CLA isomers by base conjugation of partially hydrogenated gamma-linolenic acid. 2003 Lipids pmid:12880116
Surette ME et al. Inhibition of leukotriene synthesis, pharmacokinetics, and tolerability of a novel dietary fatty acid formulation in healthy adult subjects. 2003 Clin Ther pmid:12852710
Surette ME et al. Inhibition of leukotriene biosynthesis by a novel dietary fatty acid formulation in patients with atopic asthma: a randomized, placebo-controlled, parallel-group, prospective trial. 2003 Clin Ther pmid:12852711
Whitehouse PA et al. Synergistic activity of gamma-linolenic acid and cytotoxic drugs against pancreatic adenocarcinoma cell lines. 2003 Pancreatology pmid:14526145
Song C et al. Effects of dietary n-3 or n-6 fatty acids on interleukin-1beta-induced anxiety, stress, and inflammatory responses in rats. 2003 J. Lipid Res. pmid:12837849
Gimeno RE et al. Characterization of a heart-specific fatty acid transport protein. 2003 J. Biol. Chem. pmid:12556534
Li MC et al. [Expression of Mortierella isabellina delta6-fatty acid desaturase gene in gamma-linolenic acid production in transgenic tobacco]. 2003 Sheng Wu Gong Cheng Xue Bao pmid:15966318
Vogelzang JL Fat facts and fallacies. 2003 Home Healthc Nurse pmid:14614382
Koletzko B et al. Fatty acid profiles, antioxidant status, and growth of preterm infants fed diets without or with long-chain polyunsaturated fatty acids. A randomized clinical trial. 2003 Eur J Nutr pmid:14569405
Barabino S et al. Systemic linoleic and gamma-linolenic acid therapy in dry eye syndrome with an inflammatory component. 2003 Cornea pmid:12605039
Djoussé L et al. Dietary linolenic acid is inversely associated with plasma triacylglycerol: the National Heart, Lung, and Blood Institute Family Heart Study. 2003 Am. J. Clin. Nutr. pmid:14668270
Williams HC Evening primrose oil for atopic dermatitis. 2003 BMJ pmid:14670851
Takwale A et al. Efficacy and tolerability of borage oil in adults and children with atopic eczema: randomised, double blind, placebo controlled, parallel group trial. 2003 BMJ pmid:14670885
Macrì A et al. Effect of linoleic acid and gamma-linolenic acid on tear production, tear clearance and on the ocular surface after photorefractive keratectomy. 2003 Graefes Arch. Clin. Exp. Ophthalmol. pmid:12768289
Jelińska M et al. Effects of dietary linseed, evening primrose or fish oils on fatty acid and prostaglandin E2 contents in the rat livers and 7,12-dimethylbenz[a]anthracene-induced tumours. 2003 Biochim. Biophys. Acta pmid:12697300
van Gool CJ et al. Gamma-linolenic acid supplementation for prophylaxis of atopic dermatitis--a randomized controlled trial in infants at high familial risk. 2003 Am. J. Clin. Nutr. pmid:12663296
Spector SL and Surette ME Diet and asthma: has the role of dietary lipids been overlooked in the management of asthma? 2003 Ann. Allergy Asthma Immunol. pmid:12722956
Vecera R et al. Antioxidant status, lipoprotein profile and liver lipids in rats fed on high-cholesterol diet containing currant oil rich in n-3 and n-6 polyunsaturated fatty acids. 2003 Physiol Res pmid:12678660
Seibel MM Treating hot flushes without hormone replacement therapy. 2003 J Fam Pract pmid:12681090
Wainwright PE et al. Effects of high-gamma-linolenic acid canola oil compared with borage oil on reproduction, growth, and brain and behavioral development in mice. 2003 Lipids pmid:12733750
Soeken KL et al. Herbal medicines for the treatment of rheumatoid arthritis: a systematic review. 2003 Rheumatology (Oxford) pmid:12709541
Duttaroy AK et al. Acyl-CoA thioesterase activity in human placental choriocarcinoma (BeWo), cells: effects of fatty acids. 2003 Prostaglandins Leukot. Essent. Fatty Acids pmid:12538089
Pacht ER et al. Enteral nutrition with eicosapentaenoic acid, gamma-linolenic acid, and antioxidants reduces alveolar inflammatory mediators and protein influx in patients with acute respiratory distress syndrome. 2003 Crit. Care Med. pmid:12576957
Shimizu S and Nakano M Structural characterization of triacylglycerol in several oils containing gamma-linolenic acid. 2003 Biosci. Biotechnol. Biochem. pmid:12619674