| MeSH term | MeSH ID | Detail |
|---|---|---|
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
gamma-Linolenic acid
Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.
Cross Reference
Introduction
To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid
PubChem Associated disorders and diseases
What pathways are associated with gamma-Linolenic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with gamma-Linolenic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with gamma-Linolenic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
What genes are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
What common seen animal models are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with gamma-Linolenic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Srinivas CV et al. | Safflower petals: a source of gamma linolenic acid. | 1999 | Plant Foods Hum Nutr | pmid:10646633 |
| Hornych A et al. | Effect of gamma-linolenic acid on plasma and membrane lipids and renal prostaglandins in old subjects. | 1999 | Br J Clin Pharmacol | pmid:10651470 |
| Peth JA et al. | Effects of a unique conjugate of alpha-lipoic acid and gamma-linolenic acid on insulin action in obese Zucker rats. | 2000 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:10666147 |
| Fan YY et al. | Modulation of atherogenesis by dietary gamma-linolenic acid. | 1999 | Adv. Exp. Med. Biol. | pmid:10667372 |
| Vartak S et al. | The selective cytotoxicity of gamma-linolenic acid (GLA) is associated with increased oxidative stress. | 1999 | Adv. Exp. Med. Biol. | pmid:10667373 |
| Robbins M et al. | gamma-linolenic acid (GLA)-mediated cytotoxicity in human prostate cancer cells. | 1999 | Adv. Exp. Med. Biol. | pmid:10667374 |
| Harris JE et al. | Five-lipoxygenase inhibitors reduce Panc-1 survival: synergism of MK886 with gamma linolenic acid. | 1999 | Adv. Exp. Med. Biol. | pmid:10667375 |
| Ramrath S et al. | Stimulation of cardiac glucose transport by thioctic acid and insulin. | 1999 | Horm. Metab. Res. | pmid:10668913 |
| Motaung E et al. | Cytotoxicity of combined essential fatty acids on a human prostate cancer cell line. | 1999 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10670696 |
| Davies CL et al. | Effect of gamma-linolenic acid on cellular uptake of structurally related anthracyclines in human drug sensitive and multidrug resistant bladder and breast cancer cell lines. | 1999 | Eur. J. Cancer | pmid:10673983 |
| Kenny FS et al. | Gamma linolenic acid with tamoxifen as primary therapy in breast cancer. | 2000 | Int. J. Cancer | pmid:10699943 |
| Ravichandran D et al. | Effect of 1-(gamma)linolenyl-3-eicosapentaenoyl propane diol on the growth of human pancreatic carcinoma in vitro and in vivo. | 2000 | Eur. J. Cancer | pmid:10708945 |
| Thijs C et al. | Essential fatty acids in breast milk of atopic mothers: comparison with non-atopic mothers, and effect of borage oil supplementation. | 2000 | Eur J Clin Nutr | pmid:10713746 |
| Guil-Guerrero JL et al. | Occurrence and characterization of oils rich in gamma-linolenic acid Part I: Echium seeds from Macaronesia. | 2000 | Phytochemistry | pmid:10731022 |
| Mohan IK and Das UN | Effect of L-arginine-nitric oxide system on the metabolism of essential fatty acids in chemical-induced diabetes mellitus. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10765977 |
| Leonard AE et al. | cDNA cloning and characterization of human Delta5-desaturase involved in the biosynthesis of arachidonic acid. | 2000 | Biochem. J. | pmid:10769175 |
| Jiang WG et al. | Peroxisome proliferator activated receptor-gamma (PPAR-gamma) mediates the action of gamma linolenic acid in breast cancer cells. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10780877 |
| Charnock JS | Gamma-linolenic acid provides additional protection against ventricular fibrillation in aged rats fed linoleic acid rich diets. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10780878 |
| Decsi T et al. | Effect of type of early infant feeding on fatty acid composition of plasma lipid classes in full-term infants during the second 6 months of life. | 2000 | J. Pediatr. Gastroenterol. Nutr. | pmid:10817286 |
| Preuss M et al. | Role of antioxidant enzyme expression in the selective cytotoxic response of glioma cells to gamma-linolenic acid supplementation. | 2000 | Free Radic. Biol. Med. | pmid:10832077 |
| Simán CM et al. | Failure of short-term gamma-linolenic acid treatment to reduce urinary calcium loss of diabetic rats. | 2000 | Urol. Res. | pmid:10850637 |
| Murray MJ et al. | Effects of eicosapentaenoic and gamma-linolenic acids (dietary lipids) on pulmonary surfactant composition and function during porcine endotoxemia. | 2000 | Chest | pmid:10858408 |
| Kumar KV et al. | Oxidant stress and essential fatty acids in patients with risk and established ARDS. | 2000 | Clin. Chim. Acta | pmid:10876008 |
| Kapoor R and Klimaszewski A | Efficacy of borage oil in patients with atopic eczema. | 2000 | Br. J. Dermatol. | pmid:10886164 |
| Oguogho A et al. | Prostaglandin synthesis in human lymphatics from precursor fatty acids. | 2000 | Lymphology | pmid:10897472 |
| Parker-Barnes JM et al. | Identification and characterization of an enzyme involved in the elongation of n-6 and n-3 polyunsaturated fatty acids. | 2000 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10899997 |
| Rahbeeni F et al. | The effect of evening primrose oil on the radiation response and blood flow of mouse normal and tumour tissue. | 2000 | Int. J. Radiat. Biol. | pmid:10902742 |
| Barham JB et al. | Addition of eicosapentaenoic acid to gamma-linolenic acid-supplemented diets prevents serum arachidonic acid accumulation in humans. | 2000 | J. Nutr. | pmid:10917903 |
| Arnold LE et al. | Does zinc moderate essential fatty acid and amphetamine treatment of attention-deficit/hyperactivity disorder? | 2000 | J Child Adolesc Psychopharmacol | pmid:10933121 |
| Guil-Guerrero JL et al. | Occurrence and characterization of oils rich in gamma-linolenic acid part II: fatty acids and squalene from Macaronesian Echium leaves. | 2000 | Phytochemistry | pmid:10939357 |
| Liu QY and Tan BK | Effects of cis-unsaturated fatty acids on doxorubicin sensitivity in P388/DOX resistant and P388 parental cell lines. | 2000 | Life Sci. | pmid:10954054 |
| Vinik AI et al. | Diabetic neuropathies. | 2000 | Diabetologia | pmid:10990072 |
| Oakley OR et al. | The effects of lithium gamma-linolenic acid in reversing LPBM5 MuLV induced suppression of hematopoietic progenitor cells in vitro. | 1998 Jan-Jun | Rom J Physiol | pmid:11000861 |
| Iijima S et al. | Oral supplementation with gamma-linolenic acid extracted from Mucor circinelloides improves the deformability of red blood cells in hemodialysis patients. | 2000 | Nephron | pmid:11014980 |
| Petrik MB et al. | Highly unsaturated (n-3) fatty acids, but not alpha-linolenic, conjugated linoleic or gamma-linolenic acids, reduce tumorigenesis in Apc(Min/+) mice. | 2000 | J. Nutr. | pmid:11015469 |
| Palombo JD et al. | Comparison of growth and fatty acid metabolism in rats fed diets containing equal levels of gamma-linolenic acid from high gamma-linolenic acid canola oil or borage oil. | 2000 | Lipids | pmid:11026618 |
| Pakala R et al. | Vascular smooth muscle cells preloaded with eicosapentaenoic acid and docosahexaenoic acid fail to respond to serotonin stimulation. | 2000 | Atherosclerosis | pmid:11058699 |
| Chan LW et al. | Microencapsulation of oils using sodium alginate. | 2000 Nov-Dec | J Microencapsul | pmid:11063422 |
| Takahashi Y et al. | Dietary gamma-linolenic acid in the form of borage oil causes less body fat accumulation accompanying an increase in uncoupling protein 1 mRNA level in brown adipose tissue. | 2000 | Comp. Biochem. Physiol. B, Biochem. Mol. Biol. | pmid:11079375 |
| Fokkema MR et al. | Short-term supplementation of low-dose gamma-linolenic acid (GLA), alpha-linolenic acid (ALA), or GLA plus ALA does not augment LCP omega 3 status of Dutch vegans to an appreciable extent. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11090255 |
| Worm M and Henz BM | Novel unconventional therapeutic approaches to atopic eczema. | 2000 | Dermatology (Basel) | pmid:11096188 |
| Horner NK and Lampe JW | Potential mechanisms of diet therapy for fibrocystic breast conditions show inadequate evidence of effectiveness. | 2000 | J Am Diet Assoc | pmid:11103660 |
| Harbige LS et al. | The protective effects of omega-6 fatty acids in experimental autoimmune encephalomyelitis (EAE) in relation to transforming growth factor-beta 1 (TGF-beta1) up-regulation and increased prostaglandin E2 (PGE2) production. | 2000 | Clin. Exp. Immunol. | pmid:11122253 |
| Biessels GJ et al. | The effect of gamma-linolenic acid-alpha-lipoic acid on functional deficits in the peripheral and central nervous system of streptozotocin-diabetic rats. | 2001 | J. Neurol. Sci. | pmid:11137514 |
| Kankaanpää PE et al. | The influence of polyunsaturated fatty acids on probiotic growth and adhesion. | 2001 | FEMS Microbiol. Lett. | pmid:11164299 |
| Ito Y et al. | Effects of polyunsaturated fatty acids on atrophic gastritis in a Japanese population. | 2001 | Cancer Lett. | pmid:11165751 |
| Goffman FD and Galletti S | Gamma-linolenic acid and tocopherol contents in the seed oil of 47 accessions from several Ribes species. | 2001 | J. Agric. Food Chem. | pmid:11170598 |
| Dobson G | Leaf lipids of Ribes nigrum: a plant containing 16:3, alpha-18:3, gamma-18:3 and 18:4 fatty acids. | 2000 | Biochem. Soc. Trans. | pmid:11171133 |
| Beaudoin F et al. | Production of C20 polyunsaturated fatty acids (PUFAs) by pathway engineering: identification of a PUFA elongase component from Caenorhabditis elegans. | 2000 | Biochem. Soc. Trans. | pmid:11171161 |
| Conti E et al. | gamma-Linolenic acid production by solid-state fermentation of Mucorales strains on cereals. | 2001 | Bioresour. Technol. | pmid:11198184 |