gamma-Linolenic acid

Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.

Cross Reference

Introduction

To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid

MeSH term MeSH ID Detail
Multiple Sclerosis, Relapsing-Remitting D020529 7 associated lipids
Mastocytoma D034801 3 associated lipids
Atherosclerosis D050197 85 associated lipids
Urolithiasis D052878 1 associated lipids
Acute Lung Injury D055371 33 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with gamma-Linolenic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with gamma-Linolenic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with gamma-Linolenic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with gamma-Linolenic acid

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Per page 10 20 50 100 | Total 1121
Authors Title Published Journal PubMed Link
Kavanagh T et al. Eicosapentaenoic acid and gamma-linolenic acid increase hippocampal concentrations of IL-4 and IL-10 and abrogate lipopolysaccharide-induced inhibition of long-term potentiation. 2004 Prostaglandins Leukot. Essent. Fatty Acids pmid:15041032
Papanikolaou N et al. Effects of OKY-046 and nifedipine in cyclosporine-induced renal dysfunction in rats. 1996 Prostaglandins Leukot. Essent. Fatty Acids pmid:8951993
Joubert AM et al. Comparative study of the effects of polyunsaturated fatty acids and their metabolites on cell growth and tyrosine kinase activity in oesophageal carcinoma cells. 1999 Prostaglandins Leukot. Essent. Fatty Acids pmid:10582657
Howie A et al. The influence of dietary essential fatty acids on uterine C20 and C22 fatty acid composition. 1992 Prostaglandins Leukot. Essent. Fatty Acids pmid:1502249
Navarette R et al. Dietary intake of concentrated gamma-linolenic acid (GLA)-enriched oil suppresses cutaneous level of dihomo-gamma-linolenic acid (DGLA): possible in vivo inhibition of microsomal elongation of GLA to DGLA. 1992 Prostaglandins Leukot. Essent. Fatty Acids pmid:1323857
Matsuo N et al. Effects of gamma-linolenic acid and its positional isomer pinolenic acid on immune parameters of brown-Norway rats. 1996 Prostaglandins Leukot. Essent. Fatty Acids pmid:8951990
Pham H et al. Dietary gamma-linolenate attenuates tumor growth in a rodent model of prostatic adenocarcinoma via suppression of elevated generation of PGE(2) and 5S-HETE. 2006 Prostaglandins Leukot. Essent. Fatty Acids pmid:16567086
Das UN and Rao KP Effect of gamma-linolenic acid and prostaglandins E1 on gamma-radiation and chemical-induced genetic damage to the bone marrow cells of mice. 2006 Prostaglandins Leukot. Essent. Fatty Acids pmid:16488586
de Kock M et al. The induction of apoptosis in human cervical carcinoma (HeLa) cells by gamma-linolenic acid. 1996 Prostaglandins Leukot. Essent. Fatty Acids pmid:9014218
Cleland LG et al. The effect of dietary fish oil supplement upon the content of dihomo-gammalinolenic acid in human plasma phospholipids. 1990 Prostaglandins Leukot. Essent. Fatty Acids pmid:2169063
van der Merwe CF et al. The effect of gamma-linolenic acid, an in vitro cytostatic substance contained in evening primrose oil, on primary liver cancer. A double-blind placebo controlled trial. 1990 Prostaglandins Leukot. Essent. Fatty Acids pmid:2169638
Miller MA and Morgan RJ Eicosanoids, erections and erectile dysfunction. 1994 Prostaglandins Leukot. Essent. Fatty Acids pmid:7938091
Horrobin DF et al. The effects of evening primrose oil, safflower oil and paraffin on plasma fatty acid levels in humans: choice of an appropriate placebo for clinical studies on primrose oil. 1991 Prostaglandins Leukot. Essent. Fatty Acids pmid:1871175
Arisaka M et al. Fatty acid and prostaglandin metabolism in children with diabetes mellitus. II. The effect of evening primrose oil supplementation on serum fatty acid and plasma prostaglandin levels. 1991 Prostaglandins Leukot. Essent. Fatty Acids pmid:1871184
Hrelia S et al. Kinetic analysis of delta-6-desaturation in liver microsomes: influence of gamma-linoleic acid dietary supplementation to young and old rats. 1991 Prostaglandins Leukot. Essent. Fatty Acids pmid:1808628
de Kock M et al. Differential cytotoxic effects of gamma-linolenic acid on MG-63 and HeLa cells. 1994 Prostaglandins Leukot. Essent. Fatty Acids pmid:7972263
du Toit PJ et al. The effect of gamma-linolenic acid and eicosapentaenoic acid on urokinase activity. 1994 Prostaglandins Leukot. Essent. Fatty Acids pmid:7972265
Eynard AR et al. Eicosatrienoic acid (20:3 n-9) inhibits the expression of E-cadherin and desmoglein in human squamous cell carcinoma in vitro. 1998 Prostaglandins Leukot. Essent. Fatty Acids pmid:10102382
Glen AI et al. Membrane fatty acids, niacin flushing and clinical parameters. 1996 Prostaglandins Leukot. Essent. Fatty Acids pmid:8888117
Brouwer DA et al. Gamma-linolenic acid does not augment long-chain polyunsaturated fatty acid omega-3 status. 1998 Prostaglandins Leukot. Essent. Fatty Acids pmid:9888208
Hrelia S et al. Concentration- and time-dependent effects of gamma-linolenic acid supplementation to tumor cells in culture. 1999 Prostaglandins Leukot. Essent. Fatty Acids pmid:10397404
Pakala R et al. Thromboxane A2 fails to induce proliferation of smooth muscle cells enriched with eicosapentaenoic acid and docosahexaenoic acid. 1999 Prostaglandins Leukot. Essent. Fatty Acids pmid:10397410
Woltil HA et al. Does supplementation of formula with evening primrose and fish oils augment long chain polyunsaturated fatty acid status of low birthweight infants to that of breast-fed counterparts? 1999 Prostaglandins Leukot. Essent. Fatty Acids pmid:10359022
Horrobin DF The effects of gamma-linolenic acid on breast pain and diabetic neuropathy: possible non-eicosanoid mechanisms. 1993 Prostaglandins Leukot. Essent. Fatty Acids pmid:8380930
Bell JG et al. Growth, mortality, tissue histopathology and fatty acid compositions, eicosanoid production and response to stress, in juvenile turbot fed diets rich in gamma-linolenic acid in combination with eicosapentaenoic acid or docosahexaenoic acid. 1998 Prostaglandins Leukot. Essent. Fatty Acids pmid:9690713
Botha JH et al. The role of prostaglandins in the inhibition of cultured carcinoma cell growth produced by gamma-linolenic acid. 1989 Prostaglandins Leukot. Essent. Fatty Acids pmid:2541450
Leaver HA et al. Intracellular oxidation by human glioma cell populations: effect of arachidonic acid. 2004 Prostaglandins Leukot. Essent. Fatty Acids pmid:15062847
Miles EA et al. The influence of different combinations of gamma-linolenic, stearidonic and eicosapentaenoic acids on the fatty acid composition of blood lipids and mononuclear cells in human volunteers. 2004 Prostaglandins Leukot. Essent. Fatty Acids pmid:15120716
Das UN From bench to the clinic: gamma-linolenic acid therapy of human gliomas. 2004 Prostaglandins Leukot. Essent. Fatty Acids pmid:15120717
Zurier RB et al. Human peripheral blood T lymphocyte proliferation after activation of the T cell receptor: effects of unsaturated fatty acids. 1999 May-Jun Prostaglandins Leukot. Essent. Fatty Acids pmid:10471124
Ebden P et al. A study of evening primrose seed oil in atopic asthma. 1989 Prostaglandins Leukot. Essent. Fatty Acids pmid:2717651
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Bunce OR and Abou-El-Ela SH Eicosanoid synthesis and ornithine decarboxylase activity in mammary tumors of rats fed varying levels and types of N-3 and/or N-6 fatty acids. 1990 Prostaglandins Leukot. Essent. Fatty Acids pmid:2177199
Kaku S et al. Dietary gamma-linolenic acid dose-dependently modifies fatty acid composition and immune parameters in rats. 2001 Prostaglandins Leukot. Essent. Fatty Acids pmid:11728173
Hrelia S et al. Role of gamma-linolenic acid in counteracting doxorubicin-induced damage in cultured rat cardiomyocytes. 2001 Prostaglandins Leukot. Essent. Fatty Acids pmid:11334548
Nwankwo JO and Robbins ME Peroxisome proliferator-activated receptor- gamma expression in human malignant and normal brain, breast and prostate-derived cells. 2001 Apr-May Prostaglandins Leukot. Essent. Fatty Acids pmid:11418018
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Hindo J et al. Evidence of the formation of different hydroperoxides in irradiated gamma-linolenate solutions: effect of micelle formation. 2000 Radiat. Res. pmid:10629620
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