gamma-Linolenic acid

Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.

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Introduction

To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid

MeSH term MeSH ID Detail
Carpal Tunnel Syndrome D002349 3 associated lipids
Back Pain D001416 5 associated lipids
Urolithiasis D052878 1 associated lipids
Mastocytoma D034801 3 associated lipids
Ecchymosis D004438 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with gamma-Linolenic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with gamma-Linolenic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with gamma-Linolenic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with gamma-Linolenic acid

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Authors Title Published Journal PubMed Link
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Jamal GA and Carmichael H The effect of gamma-linolenic acid on human diabetic peripheral neuropathy: a double-blind placebo-controlled trial. 1990 Diabet. Med. pmid:2159860
Sangeetha P et al. Free radical generation in human leukocytes by CIS-unsaturated fatty acids is a calmodulin dependent process. 1990 Prostaglandins Leukot. Essent. Fatty Acids pmid:2160083
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Bunce OR and Abou-El-Ela SH Eicosanoid synthesis and ornithine decarboxylase activity in mammary tumors of rats fed varying levels and types of N-3 and/or N-6 fatty acids. 1990 Prostaglandins Leukot. Essent. Fatty Acids pmid:2177199
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Kawashima Y et al. Peroxisome proliferators enhance linoleic acid metabolism in rat liver. Increased biosynthesis of omega 6 polyunsaturated fatty acids. 1990 J. Biol. Chem. pmid:2160962
Abraham RD et al. Effects of safflower oil and evening primrose oil in men with a low dihomo-gamma-linolenic level. 1990 Atherosclerosis pmid:2112389
Ikushima S et al. Gamma linolenic acid alters the cytotoxic activity of anticancer drugs on cultured human neuroblastoma cells. 1990 Jul-Aug Anticancer Res. pmid:2166461
Sircar S et al. Transformation renders MDR cells more sensitive to polyunsaturated fatty acids. 1990 Nov-Dec Anticancer Res. pmid:2178327
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Arisaka M et al. Fatty acid and prostaglandin metabolism in children with diabetes mellitus. II. The effect of evening primrose oil supplementation on serum fatty acid and plasma prostaglandin levels. 1991 Prostaglandins Leukot. Essent. Fatty Acids pmid:1871184
Gateley CA and Mansel RE Management of the painful and nodular breast. 1991 Br. Med. Bull. pmid:1834299
Hrelia S et al. Kinetic analysis of delta-6-desaturation in liver microsomes: influence of gamma-linoleic acid dietary supplementation to young and old rats. 1991 Prostaglandins Leukot. Essent. Fatty Acids pmid:1808628
Tauson AH et al. Effect of evening primrose oil as food supplement on reproduction in the mink. 1991 Acta Vet. Scand. pmid:1814183
Tauson AH and Forsberg M Effect of evening primrose oil as food supplement on reproduction in the blue fox. 1991 Acta Vet. Scand. pmid:1814184
Gardiner NS and Duncan JR Possible involvement of delta-6-desaturase in control of melanoma growth by gamma-linolenic acid. 1991 Prostaglandins Leukot. Essent. Fatty Acids pmid:1650000
Chapkin RS and Coble KJ Utilization of gammalinolenic acid by mouse peritoneal macrophages. 1991 Biochim. Biophys. Acta pmid:1655039
Freeman MS et al. The effects of essential fatty acid supplementation on lithium absorption kinetics in guinea pig jejunum. 1991 Biochem. Soc. Trans. pmid:1665438
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Gilani S et al. Chick embryonic development following exposure to ethanol, gamma-linolenic and linolenic acids. 1991 Anat Anz pmid:1666823
Kristofíková L et al. Selection of Rhizopus strains for L(+)-lactic acid and gamma-linolenic acid production. 1991 Folia Microbiol. (Praha) pmid:1668279
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Brzeski M et al. Evening primrose oil in patients with rheumatoid arthritis and side-effects of non-steroidal anti-inflammatory drugs. 1991 Br. J. Rheumatol. pmid:1913008
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Cameron NE et al. Essential fatty acid diet supplementation. Effects on peripheral nerve and skeletal muscle function and capillarization in streptozocin-induced diabetic rats. 1991 Diabetes pmid:2022301
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Ziboh VA and Fletcher MP Dose-response effects of dietary gamma-linolenic acid-enriched oils on human polymorphonuclear-neutrophil biosynthesis of leukotriene B4. 1992 Am. J. Clin. Nutr. pmid:1309474
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Navarette R et al. Dietary intake of concentrated gamma-linolenic acid (GLA)-enriched oil suppresses cutaneous level of dihomo-gamma-linolenic acid (DGLA): possible in vivo inhibition of microsomal elongation of GLA to DGLA. 1992 Prostaglandins Leukot. Essent. Fatty Acids pmid:1323857
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Duffy O et al. Attenuation of the effects of chronic ethanol administration in the brain lipid content of the developing rat by an oil enriched in gamma linolenic acid. 1992 Drug Alcohol Depend pmid:1330473
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Horrobin DF Nutritional and medical importance of gamma-linolenic acid. 1992 Prog. Lipid Res. pmid:1334266
Engler MM et al. Dietary gamma-linolenic acid lowers blood pressure and alters aortic reactivity and cholesterol metabolism in hypertension. 1992 J. Hypertens. pmid:1335001
McFayden IJ et al. Cyclical breast pain--some observations and the difficulties in treatment. 1992 Br J Clin Pract pmid:1286012
Hayashi Y et al. Anticancer effects of free polyunsaturated fatty acids in an oily lymphographic agent following intrahepatic arterial administration to a rabbit bearing VX-2 tumor. 1992 Cancer Res. pmid:1309442