gamma-Linolenic acid

Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.

Cross Reference

Introduction

To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid

MeSH term MeSH ID Detail
Carpal Tunnel Syndrome D002349 3 associated lipids
Back Pain D001416 5 associated lipids
Urolithiasis D052878 1 associated lipids
Mastocytoma D034801 3 associated lipids
Ecchymosis D004438 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with gamma-Linolenic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with gamma-Linolenic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with gamma-Linolenic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with gamma-Linolenic acid

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Authors Title Published Journal PubMed Link
Cheng Z et al. Alteration of prostaglandin production and agonist responsiveness by n-6 polyunsaturated fatty acids in endometrial cells from late-gestation ewes. 2004 J. Endocrinol. pmid:15283685
Johnston GA et al. The use of dietary manipulation by parents of children with atopic dermatitis. 2004 Br. J. Dermatol. pmid:15214908
Saevik BK et al. A randomized, controlled study to evaluate the steroid sparing effect of essential fatty acid supplementation in the treatment of canine atopic dermatitis. 2004 Vet. Dermatol. pmid:15214949
Ziboh VA et al. Suppression of leukotriene B4 generation by ex-vivo neutrophils isolated from asthma patients on dietary supplementation with gammalinolenic acid-containing borage oil: possible implication in asthma. 2004 Clin. Dev. Immunol. pmid:15154607
Agombar A et al. An aqueous formulation of gamma-linolenic acid with anti-proliferative action on human pancreatic cancer cell lines. 2004 Anticancer Drugs pmid:15075672
Dokholyan RS et al. A trial of omega-3 fatty acids for prevention of hypertension. 2004 Am. J. Cardiol. pmid:15081453
van Gool CJ et al. Oral essential fatty acid supplementation in atopic dermatitis-a meta-analysis of placebo-controlled trials. 2004 Br. J. Dermatol. pmid:15099370
Leaver HA et al. Intracellular oxidation by human glioma cell populations: effect of arachidonic acid. 2004 Prostaglandins Leukot. Essent. Fatty Acids pmid:15062847
Miles EA et al. The influence of different combinations of gamma-linolenic, stearidonic and eicosapentaenoic acids on the fatty acid composition of blood lipids and mononuclear cells in human volunteers. 2004 Prostaglandins Leukot. Essent. Fatty Acids pmid:15120716
Das UN From bench to the clinic: gamma-linolenic acid therapy of human gliomas. 2004 Prostaglandins Leukot. Essent. Fatty Acids pmid:15120717
Gallagher S Omega 3 oils and pregnancy. 2004 Midwifery Today Int Midwife pmid:15124319
Menendez JA et al. Omega-6 polyunsaturated fatty acid gamma-linolenic acid (18:3n-6) enhances docetaxel (Taxotere) cytotoxicity in human breast carcinoma cells: Relationship to lipid peroxidation and HER-2/neu expression. 2004 Oncol. Rep. pmid:15138562
Radomska A Antioxidant properties of captopril in vitro. 2003 May-Jun Acta Pol Pharm pmid:14556487
Nelson JL et al. Effect of enteral feeding with eicosapentaenoic acid, gamma-linolenic acid, and antioxidants on antioxidant status in patients with acute respiratory distress syndrome. 2003 Mar-Apr JPEN J Parenter Enteral Nutr pmid:12665164
Giamarellos-Bourboulis EJ et al. Lipid peroxidation by Pseudomonas aeruginosa in the pathogenesis of nosocomial sepsis. 2003 Jan-Mar J Postgrad Med pmid:12865564
Halat KM and Dennehy CE Botanicals and dietary supplements in diabetic peripheral neuropathy. 2003 Jan-Feb J Am Board Fam Pract pmid:12583650
Harris NM et al. Epirubicin and meglumine gamma-linolenic acid: a logical choice of combination therapy for patients with superficial bladder carcinoma. 2003 Cancer pmid:12491507
Pham H et al. Activation of peroxisome proliferator-activated receptor (PPAR)-gamma by 15S-hydroxyeicosatrienoic acid parallels growth suppression of androgen-dependent prostatic adenocarcinoma cells. 2003 Cancer Lett. pmid:12445673
Shotton HR et al. The effectiveness of treatments of diabetic autonomic neuropathy is not the same in autonomic nerves supplying different organs. 2003 Diabetes pmid:12502507
Delmonte P et al. Synthesis and isolation of trans-7,cis-9 octadecadienoic acid and other CLA isomers by base conjugation of partially hydrogenated gamma-linolenic acid. 2003 Lipids pmid:12880116
Surette ME et al. Inhibition of leukotriene synthesis, pharmacokinetics, and tolerability of a novel dietary fatty acid formulation in healthy adult subjects. 2003 Clin Ther pmid:12852710
Surette ME et al. Inhibition of leukotriene biosynthesis by a novel dietary fatty acid formulation in patients with atopic asthma: a randomized, placebo-controlled, parallel-group, prospective trial. 2003 Clin Ther pmid:12852711
Whitehouse PA et al. Synergistic activity of gamma-linolenic acid and cytotoxic drugs against pancreatic adenocarcinoma cell lines. 2003 Pancreatology pmid:14526145
Song C et al. Effects of dietary n-3 or n-6 fatty acids on interleukin-1beta-induced anxiety, stress, and inflammatory responses in rats. 2003 J. Lipid Res. pmid:12837849
Gimeno RE et al. Characterization of a heart-specific fatty acid transport protein. 2003 J. Biol. Chem. pmid:12556534
Li MC et al. [Expression of Mortierella isabellina delta6-fatty acid desaturase gene in gamma-linolenic acid production in transgenic tobacco]. 2003 Sheng Wu Gong Cheng Xue Bao pmid:15966318
Vogelzang JL Fat facts and fallacies. 2003 Home Healthc Nurse pmid:14614382
Koletzko B et al. Fatty acid profiles, antioxidant status, and growth of preterm infants fed diets without or with long-chain polyunsaturated fatty acids. A randomized clinical trial. 2003 Eur J Nutr pmid:14569405
Arimura T et al. Caspase-independent apoptosis induced by evening primrose extract in Ehrlich ascites tumor cells. 2003 Cancer Lett. pmid:14580681
Barabino S et al. Systemic linoleic and gamma-linolenic acid therapy in dry eye syndrome with an inflammatory component. 2003 Cornea pmid:12605039
Djoussé L et al. Dietary linolenic acid is inversely associated with plasma triacylglycerol: the National Heart, Lung, and Blood Institute Family Heart Study. 2003 Am. J. Clin. Nutr. pmid:14668270
Williams HC Evening primrose oil for atopic dermatitis. 2003 BMJ pmid:14670851
Takwale A et al. Efficacy and tolerability of borage oil in adults and children with atopic eczema: randomised, double blind, placebo controlled, parallel group trial. 2003 BMJ pmid:14670885
Macrì A et al. Effect of linoleic acid and gamma-linolenic acid on tear production, tear clearance and on the ocular surface after photorefractive keratectomy. 2003 Graefes Arch. Clin. Exp. Ophthalmol. pmid:12768289
Jelińska M et al. Effects of dietary linseed, evening primrose or fish oils on fatty acid and prostaglandin E2 contents in the rat livers and 7,12-dimethylbenz[a]anthracene-induced tumours. 2003 Biochim. Biophys. Acta pmid:12697300
van Gool CJ et al. Gamma-linolenic acid supplementation for prophylaxis of atopic dermatitis--a randomized controlled trial in infants at high familial risk. 2003 Am. J. Clin. Nutr. pmid:12663296
Spector SL and Surette ME Diet and asthma: has the role of dietary lipids been overlooked in the management of asthma? 2003 Ann. Allergy Asthma Immunol. pmid:12722956
Vecera R et al. Antioxidant status, lipoprotein profile and liver lipids in rats fed on high-cholesterol diet containing currant oil rich in n-3 and n-6 polyunsaturated fatty acids. 2003 Physiol Res pmid:12678660
Seibel MM Treating hot flushes without hormone replacement therapy. 2003 J Fam Pract pmid:12681090
Wainwright PE et al. Effects of high-gamma-linolenic acid canola oil compared with borage oil on reproduction, growth, and brain and behavioral development in mice. 2003 Lipids pmid:12733750
Soeken KL et al. Herbal medicines for the treatment of rheumatoid arthritis: a systematic review. 2003 Rheumatology (Oxford) pmid:12709541
Duttaroy AK et al. Acyl-CoA thioesterase activity in human placental choriocarcinoma (BeWo), cells: effects of fatty acids. 2003 Prostaglandins Leukot. Essent. Fatty Acids pmid:12538089
Pacht ER et al. Enteral nutrition with eicosapentaenoic acid, gamma-linolenic acid, and antioxidants reduces alveolar inflammatory mediators and protein influx in patients with acute respiratory distress syndrome. 2003 Crit. Care Med. pmid:12576957
Xian M et al. Production of gamma-linolenic acid by disrupted mycelia of Mortierella isabellina. 2003 Lett. Appl. Microbiol. pmid:12581380
Rosenstein ED et al. Pilot study of dietary fatty acid supplementation in the treatment of adult periodontitis. 2003 Prostaglandins Leukot. Essent. Fatty Acids pmid:12591005
Usami M et al. Effect of gamma-linolenic acid or docosahexaenoic acid on tight junction permeability in intestinal monolayer cells and their mechanism by protein kinase C activation and/or eicosanoid formation. 2003 Nutrition pmid:12591548
Hirano A et al. Arachidonic acid-induced channel- and carrier-type ion transport across planar bilayer lipid membranes. 2003 Anal Sci pmid:12608744
Shimizu S and Nakano M Structural characterization of triacylglycerol in several oils containing gamma-linolenic acid. 2003 Biosci. Biotechnol. Biochem. pmid:12619674
Funtikova NS et al. [Synthesis of biologically active lipids by fungus Mucor lusitanicus 306D grown on media with various composition]. 2002 Nov-Dec Prikl. Biokhim. Mikrobiol. pmid:12449793
Das UN Abrupt and complete occlusion of tumor-feeding vessels by gamma-linolenic acid. 2002 Jul-Aug Nutrition pmid:12093450