gamma-Linolenic acid

Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.

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Introduction

To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid

MeSH term MeSH ID Detail
Urolithiasis D052878 1 associated lipids
Mucocele D009078 1 associated lipids
Fibrocystic Breast Disease D005348 1 associated lipids
Salivary Gland Diseases D012466 1 associated lipids
Tietze's Syndrome D013991 1 associated lipids
Fallopian Tube Neoplasms D005185 1 associated lipids
Scurvy D012614 2 associated lipids
Carcinoma, Mucoepidermoid D018277 3 associated lipids
Arthritis, Psoriatic D015535 3 associated lipids
Mastocytoma D034801 3 associated lipids
Ecchymosis D004438 3 associated lipids
Pityriasis D010915 3 associated lipids
Carpal Tunnel Syndrome D002349 3 associated lipids
Gastritis, Atrophic D005757 4 associated lipids
Back Pain D001416 5 associated lipids
Hand Dermatoses D006229 5 associated lipids
Intermittent Claudication D007383 6 associated lipids
Xerostomia D014987 6 associated lipids
Premenstrual Syndrome D011293 7 associated lipids
Raynaud Disease D011928 7 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with gamma-Linolenic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with gamma-Linolenic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with gamma-Linolenic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with gamma-Linolenic acid

Download all related citations
Per page 10 20 50 100 | Total 1121
Authors Title Published Journal PubMed Link
Willemaers V et al. [Atopic dermatitis]. 1998 Rev Med Liege pmid:9564223
Hørby Jørgensen M et al. Effect of formula supplemented with docosahexaenoic acid and gamma-linolenic acid on fatty acid status and visual acuity in term infants. 1998 J. Pediatr. Gastroenterol. Nutr. pmid:9552137
Solomon LZ et al. Is gamma-linolenic acid an effective intravesical agent for superficial bladder cancer? In vitro cytotoxicity and in vivo tolerance studies. 1998 Urol. Res. pmid:9537690
Kis M et al. Light-induced expression of fatty acid desaturase genes. 1998 Proc. Natl. Acad. Sci. U.S.A. pmid:9539715
Cameron NE et al. Effects of alpha-lipoic acid on neurovascular function in diabetic rats: interaction with essential fatty acids. 1998 Diabetologia pmid:9562342
van Rooyen J et al. Diet can manipulate the metabolism of EPA and GLA in erythrocyte membrane and plasma. 1998 Prostaglandins Leukot. Essent. Fatty Acids pmid:9758205
Jiang WG et al. gamma-Linolenic acid blocks cell cycle progression by regulating phosphorylation of p27kip1 and p57kip2 and their interactions with other cycle regulators in cancer cells. 1998 Int. J. Oncol. pmid:9683802
Villalobos MA et al. Effect of dietary supplementation with evening primrose oil on vascular thrombogenesis in hyperlipemic rabbits. 1998 Thromb. Haemost. pmid:9798993
Eynard AR et al. Eicosatrienoic acid (20:3 n-9) inhibits the expression of E-cadherin and desmoglein in human squamous cell carcinoma in vitro. 1998 Prostaglandins Leukot. Essent. Fatty Acids pmid:10102382
Brouwer DA et al. Gamma-linolenic acid does not augment long-chain polyunsaturated fatty acid omega-3 status. 1998 Prostaglandins Leukot. Essent. Fatty Acids pmid:9888208
Seegers JC et al. Comparative anti-mitotic effects of lithium gamma-linolenate, gamma-linolenic acid and arachidonic acid, on transformed and embryonic cells. 1998 Prostaglandins Leukot. Essent. Fatty Acids pmid:9849656
Leng GC et al. Randomized controlled trial of gamma-linolenic acid and eicosapentaenoic acid in peripheral arterial disease. 1998 Clin Nutr pmid:10205349
Hounsom L et al. A lipoic acid-gamma linolenic acid conjugate is effective against multiple indices of experimental diabetic neuropathy. 1998 Diabetologia pmid:9686927
Kumamoto T and Ide T Comparative effects of alpha- and gamma-linolenic acids on rat liver fatty acid oxidation. 1998 Lipids pmid:9688166
Bell JG et al. Growth, mortality, tissue histopathology and fatty acid compositions, eicosanoid production and response to stress, in juvenile turbot fed diets rich in gamma-linolenic acid in combination with eicosapentaenoic acid or docosahexaenoic acid. 1998 Prostaglandins Leukot. Essent. Fatty Acids pmid:9690713
Ravichandran D et al. Growth inhibitory effect of lithium gammalinolenate on pancreatic cancer cell lines: the influence of albumin and iron. 1998 Eur. J. Cancer pmid:9624256
Sanderson P and Calder PC Dietary fish oil appears to prevent the activation of phospholipase C-gamma in lymphocytes. 1998 Biochim. Biophys. Acta pmid:9630688
Martens-Lobenhoffer J and Meyer FP Pharmacokinetic data of gamma-linolenic acid in healthy volunteers after the administration of evening primrose oil (Epogam). 1998 Int J Clin Pharmacol Ther pmid:9707349
Johnson SR Premenstrual syndrome therapy. 1998 Clin Obstet Gynecol pmid:9646973
Engler MM et al. Effects of dietary gamma-linolenic acid on blood pressure and adrenal angiotensin receptors in hypertensive rats. 1998 Proc. Soc. Exp. Biol. Med. pmid:9648942
Giamarellos-Bourboulis EJ et al. In vitro activity of polyunsaturated fatty acids on Pseudomonas aeruginosa: relationship to lipid peroxidation. 1998 Prostaglandins Leukot. Essent. Fatty Acids pmid:9654401
Kahler CP and Du Plooy WJ Effect of gammalinolenic acid, dihomogammalinolenic acid, ascorbyl-6-gammalinolenic acid, and ascorbyl-6-dihomo gammalinolenic acid on histamine- and methacholine-induced contraction of the isolated guinea pig tracheal chain. 1998 Prostaglandins Leukot. Essent. Fatty Acids pmid:9654407
Reilly JD et al. Effect of a supplementary dietary evening primrose oil mixture on hoof growth, hoof growth rate and hoof lipid fractions in horses: a controlled and blinded trial. 1998 Equine Vet J Suppl pmid:9932095
Kruger MC et al. Calcium, gamma-linolenic acid and eicosapentaenoic acid supplementation in senile osteoporosis. 1998 Aging (Milano) pmid:9932142
Ramesh G and Das UN Effect of evening primrose and fish oils on two stage skin carcinogenesis in mice. 1998 Prostaglandins Leukot. Essent. Fatty Acids pmid:9844986
Kuruvilla R et al. Evening primrose oil treatment corrects reduced conduction velocity but not depletion of arachidonic acid in nerve from streptozotocin-induced diabetic rats. 1998 Prostaglandins Leukot. Essent. Fatty Acids pmid:9844993
Schellhammer PF Intravesical chemotherapy with gamma linolenic acid becomes a reality. 1998 J. Urol. pmid:9817299
Solomon LZ et al. Intravesical chemotherapy with gamma linolenic acid becomes a realistic prospect in serum-free applications: in vitro cytotoxicity and systemic absorption studies. 1998 J. Urol. pmid:9817384
Chen Q et al. Analysis of the acyl-CoAs that accumulate during the peroxisomal beta-oxidation of arachidonic acid and 6,9,12-octadecatrienoic acid. 1998 Arch. Biochem. Biophys. pmid:9448727
Jiang WG et al. The effects of n-6 polyunsaturated fatty acids on the expression of nm-23 in human cancer cells. 1998 Br. J. Cancer pmid:9514051
Gu JY et al. Effect of dietary fats and sesamin on the lipid metabolism and immune function of Sprague-Dawley rats. 1998 Biosci. Biotechnol. Biochem. pmid:9836427
Frati-Munari AC and Ariza-Andraca CR [Treatment of diabetic neuropathy]. 1998 Jan-Feb Gac Med Mex pmid:9658700
Oakley OR et al. The effects of lithium gamma-linolenic acid in reversing LPBM5 MuLV induced suppression of hematopoietic progenitor cells in vitro. 1998 Jan-Jun Rom J Physiol pmid:11000861
Burnard SL et al. Cilazapril and dietary gamma-linolenic acid prevent the deficit in sciatic nerve conduction velocity in the streptozotocin diabetic rat. 1998 Mar-Apr J. Diabetes Complicat. pmid:9559483
Anderson KM et al. Five-lipoxygenase inhibitors reduce Panc-1 survival: the mode of cell death and synergism of MK886 with gamma linolenic acid. 1998 Mar-Apr Anticancer Res. pmid:9615721
Stahl A et al. Identification of the major intestinal fatty acid transport protein. 1999 Mol. Cell pmid:10518211
Cai J et al. Inhibition of angiogenic factor- and tumour-induced angiogenesis by gamma linolenic acid. 1999 Prostaglandins Leukot. Essent. Fatty Acids pmid:10319914
Ihara-Watanabe M et al. Effects of dietary alpha- or gamma-linolenic acid on levels and fatty acid compositions of serum and hepatic lipids, and activity and mRNA abundance of 3-hydroxy-3-methylglutaryl CoA reductase in rats. 1999 Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. pmid:10327618
Giamarellos-Bourboulis EJ et al. In vitro interactions of gamma-linolenic acid and arachidonic acid with ceftazidime on multiresistant Pseudomonas aeruginosa. 1999 Lipids pmid:10419130
Hrelia S et al. Concentration- and time-dependent effects of gamma-linolenic acid supplementation to tumor cells in culture. 1999 Prostaglandins Leukot. Essent. Fatty Acids pmid:10397404
Pakala R et al. Thromboxane A2 fails to induce proliferation of smooth muscle cells enriched with eicosapentaenoic acid and docosahexaenoic acid. 1999 Prostaglandins Leukot. Essent. Fatty Acids pmid:10397410
Warren G et al. The role of essential fatty acids in chronic fatigue syndrome. A case-controlled study of red-cell membrane essential fatty acids (EFA) and a placebo-controlled treatment study with high dose of EFA. 1999 Acta Neurol. Scand. pmid:10071170
Muñoz SE et al. Differential effects of dietary Oenothera, Zizyphus mistol, and corn oils, and essential fatty acid deficiency on the progression of a murine mammary gland adenocarcinoma. 1999 Nutrition pmid:10198915
Tamimi NA et al. Role of gamma-linolenic acid in uraemic pruritus. 1999 Nephron pmid:10516500
Wu D et al. Effect of dietary supplementation with black currant seed oil on the immune response of healthy elderly subjects. 1999 Am. J. Clin. Nutr. pmid:10500023
Peterson LD et al. Dose-dependent effects of dietary gamma-linolenic acid on rat spleen lymphocyte functions. 1999 Prostaglandins Leukot. Essent. Fatty Acids pmid:10477037
Haag M et al. Polyunsaturated fatty acids inhibit Mg2+ -ATPase in basolateral membranes from rat enterocytes. 1999 Prostaglandins Leukot. Essent. Fatty Acids pmid:10477038
Huang YS et al. Cloning of delta12- and delta6-desaturases from Mortierella alpina and recombinant production of gamma-linolenic acid in Saccharomyces cerevisiae. 1999 Lipids pmid:10478922
Khamaisi M et al. Metabolic effects of gamma-linolenic acid-alpha-lipoic acid conjugate in streptozotocin diabetic rats. 1999 Antioxid. Redox Signal. pmid:11233149
Redden PR et al. Acyloxymethyl acidic drug derivatives: in vitro hydrolytic reactivity. 1999 Int J Pharm pmid:10370185