gamma-Linolenic acid

Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.

Cross Reference

Introduction

To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid

MeSH term MeSH ID Detail
Urolithiasis D052878 1 associated lipids
Fallopian Tube Neoplasms D005185 1 associated lipids
Fibrocystic Breast Disease D005348 1 associated lipids
Mucocele D009078 1 associated lipids
Tietze's Syndrome D013991 1 associated lipids
Salivary Gland Diseases D012466 1 associated lipids
Scurvy D012614 2 associated lipids
Mastocytoma D034801 3 associated lipids
Carpal Tunnel Syndrome D002349 3 associated lipids
Ecchymosis D004438 3 associated lipids
Carcinoma, Mucoepidermoid D018277 3 associated lipids
Arthritis, Psoriatic D015535 3 associated lipids
Pityriasis D010915 3 associated lipids
Gastritis, Atrophic D005757 4 associated lipids
Back Pain D001416 5 associated lipids
Hand Dermatoses D006229 5 associated lipids
Xerostomia D014987 6 associated lipids
Intermittent Claudication D007383 6 associated lipids
Postoperative Hemorrhage D019106 7 associated lipids
Nausea D009325 7 associated lipids
Premenstrual Syndrome D011293 7 associated lipids
Bacteriuria D001437 7 associated lipids
Raynaud Disease D011928 7 associated lipids
Kidney Calculi D007669 7 associated lipids
Food Hypersensitivity D005512 7 associated lipids
Multiple Sclerosis, Relapsing-Remitting D020529 7 associated lipids
Ascorbic Acid Deficiency D001206 9 associated lipids
Dysmenorrhea D004412 9 associated lipids
Respiratory Insufficiency D012131 10 associated lipids
Dermatitis, Seborrheic D012628 10 associated lipids
Fatigue D005221 10 associated lipids
Critical Illness D016638 13 associated lipids
Dyskinesia, Drug-Induced D004409 15 associated lipids
Synovitis D013585 15 associated lipids
Respiratory Distress Syndrome, Adult D012128 15 associated lipids
Scleroderma, Systemic D012595 16 associated lipids
Liver Cirrhosis, Alcoholic D008104 17 associated lipids
Dermatitis, Atopic D003876 19 associated lipids
Leukemia, Myeloid, Acute D015470 19 associated lipids
Erectile Dysfunction D007172 19 associated lipids
Carcinoma 256, Walker D002279 22 associated lipids
Neoplasm Invasiveness D009361 23 associated lipids
Neoplasms, Hormone-Dependent D009376 23 associated lipids
Cardiovascular Diseases D002318 24 associated lipids
Encephalomyelitis, Autoimmune, Experimental D004681 26 associated lipids
Gastritis D005756 27 associated lipids
Alcoholism D000437 27 associated lipids
Dermatitis D003872 30 associated lipids
Acute Lung Injury D055371 33 associated lipids
Hyperplasia D006965 34 associated lipids
Per page 10 20 50 100 | Total 85

PubChem Associated disorders and diseases

What pathways are associated with gamma-Linolenic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with gamma-Linolenic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with gamma-Linolenic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with gamma-Linolenic acid

Download all related citations
Per page 10 20 50 100 | Total 1121
Authors Title Published Journal PubMed Link
Dickerson RN Modified EN support for patients with acute respiratory distress syndrome. 2008 Nov-Dec JPEN J Parenter Enteral Nutr pmid:18974252
Nasrollahzadeh J et al. The influence of feeding linoleic, gamma-linolenic and docosahexaenoic acid rich oils on rat brain tumor fatty acids composition and fatty acid binding protein 7 mRNA expression. 2008 Lipids Health Dis pmid:19014610
Won J et al. Stability analysis of zinc oxide-nanoencapsulated conjugated linoleic acid and gamma-linolenic acid. 2008 J. Food Sci. pmid:19019122
Nandakumar M and Tan MW Gamma-linolenic and stearidonic acids are required for basal immunity in Caenorhabditis elegans through their effects on p38 MAP kinase activity. 2008 PLoS Genet. pmid:19023415
Senapati S et al. Evening primrose oil is effective in atopic dermatitis: a randomized placebo-controlled trial. 2008 Sep-Oct Indian J Dermatol Venereol Leprol pmid:19052401
Brzeski M et al. Evening primrose oil in patients with rheumatoid arthritis and side-effects of non-steroidal anti-inflammatory drugs. 1991 Br. J. Rheumatol. pmid:1913008
Lu H et al. Identification and characterization of a novel delta6-fatty acid desaturase gene from Rhizopus nigricans. 2009 Mol. Biol. Rep. pmid:19152021
Wright S Atopic eczema. 1991 J R Coll Physicians Lond pmid:1920221
Schnebelen C et al. Dietary n-3 and n-6 PUFA enhance DHA incorporation in retinal phospholipids without affecting PGE(1) and PGE (2) levels. 2009 Lipids pmid:19242743
Shi LM et al. [Effects of gamma linolenic acid on atherosclerosis induced by cholesterol-rich diet in rats]. 2008 Zhongguo Zhong Yao Za Zhi pmid:19260318
Kong X et al. Gamma-linolenic acid modulates the response of multidrug-resistant K562 leukemic cells to anticancer drugs. 2009 Toxicol In Vitro pmid:19268700
Miyake JA et al. Gamma-linolenic acid inhibits both tumour cell cycle progression and angiogenesis in the orthotopic C6 glioma model through changes in VEGF, Flt1, ERK1/2, MMP2, cyclin D1, pRb, p53 and p27 protein expression. 2009 Lipids Health Dis pmid:19292920
Recently introduced products. 1991 Drug Ther Bull pmid:1935601
Ge H et al. Gamma-linolenic acid induces apoptosis and lipid peroxidation in human chronic myelogenous leukemia K562 cells. 2009 Cell Biol. Int. pmid:19356705
Weaver KL et al. Effect of dietary fatty acids on inflammatory gene expression in healthy humans. 2009 J. Biol. Chem. pmid:19359242
Viau S et al. Efficacy of a 2-month dietary supplementation with polyunsaturated fatty acids in dry eye induced by scopolamine in a rat model. 2009 Graefes Arch. Clin. Exp. Ophthalmol. pmid:19415319
Schäfer L and Kragballe K Supplementation with evening primrose oil in atopic dermatitis: effect on fatty acids in neutrophils and epidermis. 1991 Lipids pmid:1943500
Ring J and Kleinheinz A [Evening primrose oil in neurodermatitis?]. 1991 Med Monatsschr Pharm pmid:1943974
Schnebelen C et al. Nutrition for the eye: different susceptibility of the retina and the lacrimal gland to dietary omega-6 and omega-3 polyunsaturated fatty acid incorporation. 2009 Ophthalmic Res. pmid:19451735
Jangbua P et al. Gamma-linolenic acid production of Mucor rouxii by solid-state fermentation using agricultural by-products. 2009 Lett. Appl. Microbiol. pmid:19453951
Di Geronimo G et al. Treatment of carpal tunnel syndrome with alpha-lipoic acid. 2009 Mar-Apr Eur Rev Med Pharmacol Sci pmid:19499849
Smyk B et al. Steady-state and time-resolved fluorescence studies of stripped Borage oil. 2009 Anal. Chim. Acta pmid:19523559
Ruiz-Rodriguez A et al. Recent trends in the advanced analysis of bioactive fatty acids. 2010 J Pharm Biomed Anal pmid:19525080
Fakas S et al. Fatty acid composition in lipid fractions lengthwise the mycelium of Mortierella isabellina and lipid production by solid state fermentation. 2009 Bioresour. Technol. pmid:19574039
Schrek R An animal model for intractable chronic lymphocytic leukemia. 1990 Med. Hypotheses pmid:1963468
Hayashi Y et al. Anticancer activity of free gamma-linolenic acid on AH-109A rat hepatoma cells and the effect of serum albumin on anticancer activity of gamma-linolenic acid in vitro. 1990 J. Pharmacobio-dyn. pmid:1965510
Sharpe GR and Farr PM Evening primrose oil and eczema. 1990 Lancet pmid:1969047
Horrobin DF and Stewart C Evening primrose oil in atopic eczema. 1990 Lancet pmid:1969596
Sharpe GR and Farr PM Evening primrose oil and eczema. 1990 Lancet pmid:1971352
Platzbecker U et al. Reduction of 5-azacitidine induced skin reactions in MDS patients with evening primrose oil. 2010 Ann. Hematol. pmid:19714330
Horrobin DF and Stewart C Evening primrose oil and atopic eczema. 1990 Lancet pmid:1973228
Zaniewska A et al. The activity of lysosomal exoglycosidases in serum of alcohol-dependent men supplemented with borage oil enriched with vitamin E. 2009 J Med Food pmid:19735195
Chapkin RS and Carmichael SL Effect of dietary blackcurrant seed oil on mouse macrophage subclasses of choline and ethanolamine glycerophospholipids. 1990 J. Nutr. pmid:1974284
Riaz A et al. Assessment of anticoagulant effect of evening primrose oil. 2009 Pak J Pharm Sci pmid:19783511
Habermann N et al. Effects of fatty acids on metabolism and cell growth of human colon cell lines of different transformation state. 2009 Sep-Oct Biofactors pmid:19798733
Tsai NP et al. Activation of testicular orphan receptor 4 by fatty acids. 2009 Nov-Dec Biochim. Biophys. Acta pmid:19800043
Lindemann J et al. Clinical study of the effects on asthma-related QOL and asthma management of a medical food in adult asthma patients. 2009 Curr Med Res Opin pmid:19811112
Lísa M et al. Comparison of various types of stationary phases in non-aqueous reversed-phase high-performance liquid chromatography-mass spectrometry of glycerolipids in blackcurrant oil and its enzymatic hydrolysis mixture. 2009 J Chromatogr A pmid:19837411
Chang CS et al. Gamma-linolenic acid inhibits inflammatory responses by regulating NF-kappaB and AP-1 activation in lipopolysaccharide-induced RAW 264.7 macrophages. 2010 Inflammation pmid:19842026
Rodgers A et al. Evening primrose oil supplementation increases citraturia and decreases other urinary risk factors for calcium oxalate urolithiasis. 2009 J. Urol. pmid:19846138
Labruzzo BA et al. Which complementary therapies can help patients with PMS? 2009 J Fam Pract pmid:19874736
Wan X et al. Production of gamma-linolenic acid in Pichia pastoris by Expression of a delta-6 desaturase gene from Cunninghamella echinulata. 2009 J. Microbiol. Biotechnol. pmid:19884765
Ranieri M et al. The use of alpha-lipoic acid (ALA), gamma linolenic acid (GLA) and rehabilitation in the treatment of back pain: effect on health-related quality of life. 2009 Jul-Sep Int J Immunopathol Pharmacol pmid:19887043
Kishino S et al. Microbial production of conjugated gamma-linolenic acid from gamma-linolenic acid by Lactobacillus plantarum AKU 1009a. 2010 J. Appl. Microbiol. pmid:19919619
Ribeiro G et al. The novel ruthenium-gamma-linolenic complex [Ru(2)(aGLA)(4)Cl] inhibits C6 rat glioma cell proliferation and induces changes in mitochondrial membrane potential, increased reactive oxygen species generation and apoptosis in vitro. 2010 Cell Biochem. Funct. pmid:19927275
Cameron M et al. Evidence of effectiveness of herbal medicinal products in the treatment of arthritis. Part 2: Rheumatoid arthritis. 2009 Phytother Res pmid:19941324
Simpson LO Melanoma and fatty acids. 1991 N. Z. Med. J. pmid:1996191
Scheim DE Cytotoxicity of unsaturated fatty acids in fresh human tumor explants: concentration thresholds and implications for clinical efficacy. 2009 Lipids Health Dis pmid:20003514
Barar J et al. Barrier functionality and transport machineries of human ECV304 cells. 2010 Med. Sci. Monit. pmid:20037486
Fa-lin Z et al. Efficacy of blackcurrant oil soft capsule, a Chinese herbal drug, in hyperlipidemia treatment. 2010 Phytother Res pmid:20041414