gamma-Linolenic acid
Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.
Cross Reference
Introduction
To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid
PubChem Associated disorders and diseases
What pathways are associated with gamma-Linolenic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with gamma-Linolenic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with gamma-Linolenic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
What genes are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
What common seen animal models are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with gamma-Linolenic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
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| Cheng Z et al. | Alteration of prostaglandin production and agonist responsiveness by n-6 polyunsaturated fatty acids in endometrial cells from late-gestation ewes. | 2004 | J. Endocrinol. | pmid:15283685 |
| Bruder ED et al. | Metabolic consequences of hypoxia from birth and dexamethasone treatment in the neonatal rat: comprehensive hepatic lipid and fatty acid profiling. | 2004 | Endocrinology | pmid:15271879 |
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| Saevik BK et al. | A randomized, controlled study to evaluate the steroid sparing effect of essential fatty acid supplementation in the treatment of canine atopic dermatitis. | 2004 | Vet. Dermatol. | pmid:15214949 |
| Johnston GA et al. | The use of dietary manipulation by parents of children with atopic dermatitis. | 2004 | Br. J. Dermatol. | pmid:15214908 |
| Pham H et al. | Suppression of cyclooxygenase-2 overexpression by 15S-hydroxyeicosatrienoic acid in androgen-dependent prostatic adenocarcinoma cells. | 2004 | Int. J. Cancer | pmid:15197770 |
| Liu JW et al. | Effect of long-term dietary supplementation of high-gamma-linolenic canola oil versus borage oil on growth, hematology, serum biochemistry, and N-6 fatty acid metabolism in rats. | 2004 | J. Agric. Food Chem. | pmid:15186123 |
| Miles EA et al. | The influence of different combinations of gamma-linolenic acid, stearidonic acid and EPA on immune function in healthy young male subjects. | 2004 | Br. J. Nutr. | pmid:15182393 |
| Torres CF et al. | Lipase-catalyzed ethanolysis of borage oil: a kinetic study. | 2004 May-Jun | Biotechnol. Prog. | pmid:15176879 |
| Remans PH et al. | Nutrient supplementation with polyunsaturated fatty acids and micronutrients in rheumatoid arthritis: clinical and biochemical effects. | 2004 | Eur J Clin Nutr | pmid:15164103 |
| Knorr R and Hamburger M | Quantitative analysis of anti-inflammatory and radical scavenging triterpenoid esters in evening primrose oil. | 2004 | J. Agric. Food Chem. | pmid:15161190 |
| Ziboh VA et al. | Suppression of leukotriene B4 generation by ex-vivo neutrophils isolated from asthma patients on dietary supplementation with gammalinolenic acid-containing borage oil: possible implication in asthma. | 2004 | Clin. Dev. Immunol. | pmid:15154607 |
| Menendez JA et al. | Overexpression and hyperactivity of breast cancer-associated fatty acid synthase (oncogenic antigen-519) is insensitive to normal arachidonic fatty acid-induced suppression in lipogenic tissues but it is selectively inhibited by tumoricidal alpha-linolenic and gamma-linolenic fatty acids: a novel mechanism by which dietary fat can alter mammary tumorigenesis. | 2004 | Int. J. Oncol. | pmid:15138577 |
| Menendez JA et al. | Omega-6 polyunsaturated fatty acid gamma-linolenic acid (18:3n-6) enhances docetaxel (Taxotere) cytotoxicity in human breast carcinoma cells: Relationship to lipid peroxidation and HER-2/neu expression. | 2004 | Oncol. Rep. | pmid:15138562 |
| Karia C et al. | Simultaneous permeation of tamoxifen and gamma linolenic acid across excised human skin. Further evidence of the permeation of solvated complexes. | 2004 | Int J Pharm | pmid:15129999 |
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| Shotton HR et al. | Prevention and partial reversal of diabetes-induced changes in enteric nerves of the rat ileum by combined treatment with alpha-lipoic acid and evening primrose oil. | 2004 | Auton Neurosci | pmid:15109939 |
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| Dokholyan RS et al. | A trial of omega-3 fatty acids for prevention of hypertension. | 2004 | Am. J. Cardiol. | pmid:15081453 |
| Agombar A et al. | An aqueous formulation of gamma-linolenic acid with anti-proliferative action on human pancreatic cancer cell lines. | 2004 | Anticancer Drugs | pmid:15075672 |
| Fewtrell MS et al. | Randomized, double-blind trial of long-chain polyunsaturated fatty acid supplementation with fish oil and borage oil in preterm infants. | 2004 | J. Pediatr. | pmid:15069395 |
| Leaver HA et al. | Intracellular oxidation by human glioma cell populations: effect of arachidonic acid. | 2004 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:15062847 |
| Plowman PN | Re: Packer RJ. Effects of radiotherapy on the brain. Med Pediatr Oncol 2003;41:448-449. | 2004 | Pediatr Blood Cancer | pmid:15049029 |
| Nakanishi T et al. | Gamma-linolenic acid prevents conjugated linoleic acid-induced fatty liver in mice. | 2004 | Nutrition | pmid:15043857 |
| Kavanagh T et al. | Eicosapentaenoic acid and gamma-linolenic acid increase hippocampal concentrations of IL-4 and IL-10 and abrogate lipopolysaccharide-induced inhibition of long-term potentiation. | 2004 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:15041032 |
| Menendez JA et al. | Omega-6 polyunsaturated fatty acid gamma-linolenic acid (18:3n-6) is a selective estrogen-response modulator in human breast cancer cells: gamma-linolenic acid antagonizes estrogen receptor-dependent transcriptional activity, transcriptionally represses estrogen receptor expression and synergistically enhances tamoxifen and ICI 182,780 (Faslodex) efficacy in human breast cancer cells. | 2004 | Int. J. Cancer | pmid:15027132 |
| Howie A et al. | The influence of dietary essential fatty acids on uterine C20 and C22 fatty acid composition. | 1992 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:1502249 |
| Gamma-linolenic acid (GLA). Monograph. | 2004 | Altern Med Rev | pmid:15005646 | |
| Del Castillo ML et al. | Fatty acid content and juice characteristics in black currant (Ribes nigrum L.) genotypes. | 2004 | J. Agric. Food Chem. | pmid:14969555 |
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| Bond R and Lloyd DH | A double-blind comparison of olive oil and a combination of evening primrose oil and fish oil in the management of canine atopy. | 1992 | Vet. Rec. | pmid:1481346 |