Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.
To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Thies F et al. | Influence of dietary supplementation with long-chain n-3 or n-6 polyunsaturated fatty acids on blood inflammatory cell populations and functions and on plasma soluble adhesion molecules in healthy adults. | 2001 | Lipids | pmid:11795850 |
Yoon S et al. | The therapeutic effect of evening primrose oil in atopic dermatitis patients with dry scaly skin lesions is associated with the normalization of serum gamma-interferon levels. | 2002 Jan-Feb | Skin Pharmacol. Appl. Skin Physiol. | pmid:11803254 |
Senanayake SP and Shahidi F | Structured lipids via lipase-catalyzed incorporation of eicosapentaenoic acid into borage (Borago officinalis L.) and evening primrose (Oenothera biennis L.) oils. | 2002 | J. Agric. Food Chem. | pmid:11804516 |
Tso P et al. | Intestinal absorption and lymphatic transport of a high gamma-linolenic acid canola oil in lymph fistula Sprague-Dawley rats. | 2002 | J. Nutr. | pmid:11823581 |
Gema H et al. | Production of gamma-linolenic acid by Cunninghamella echinulata cultivated on glucose and orange peel. | 2002 | Appl. Microbiol. Biotechnol. | pmid:11935180 |
Crook TJ et al. | The effects of meglumine gamma linolenic acid (MeGLA) on an organ culture model of superficial bladder cancer. | 2002 | Urol. Res. | pmid:11942327 |
Furse RK et al. | Oral administration of gammalinolenic acid, an unsaturated fatty acid with anti-inflammatory properties, modulates interleukin-1beta production by human monocytes. | 2002 | J. Clin. Immunol. | pmid:11998897 |
Patel GK and Logan RA | Golden nail pigmentation. | 2002 | J Dermatolog Treat | pmid:12006139 |
Leigh-Firbank EC et al. | Eicosapentaenoic acid and docosahexaenoic acid from fish oils: differential associations with lipid responses. | 2002 | Br. J. Nutr. | pmid:12010583 |
Braddock R et al. | gamma-Linoleic acid and ascorbic acid ameliorate the effects of experimental diabetes on electrolyte and bone homeostasis in pregnant rats. | 2002 | J. Endocrinol. | pmid:12010635 |
Hong H et al. | High-level production of gamma-linolenic acid in Brassica juncea using a delta6 desaturase from Pythium irregulare. | 2002 | Plant Physiol. | pmid:12011365 |
GarcÃa-Maroto F et al. | Cloning and molecular characterization of the delta6-desaturase from two echium plant species: production of GLA by heterologous expression in yeast and tobacco. | 2002 | Lipids | pmid:12030323 |
Leaver HA et al. | Antitumour and pro-apoptotic actions of highly unsaturated fatty acids in glioma. | 2002 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12051954 |
Menéndez JA et al. | Synergistic interaction between vinorelbine and gamma-linolenic acid in breast cancer cells. | 2002 | Breast Cancer Res. Treat. | pmid:12058962 |
Cook D et al. | Modification of fatty acid composition in tomato (Lycopersicon esculentum) by expression of a borage delta6-desaturase. | 2002 | Mol. Biotechnol. | pmid:12059112 |
Colquhoun A | Gamma-linolenic acid alters the composition of mitochondrial membrane subfractions, decreases outer mitochondrial membrane binding of hexokinase and alters carnitine palmitoyltransferase I properties in the Walker 256 rat tumour. | 2002 | Biochim. Biophys. Acta | pmid:12069851 |
Das UN | Abrupt and complete occlusion of tumor-feeding vessels by gamma-linolenic acid. | 2002 Jul-Aug | Nutrition | pmid:12093450 |
Banni S et al. | Vaccenic acid feeding increases tissue levels of conjugated linoleic acid and suppresses development of premalignant lesions in rat mammary gland. | 2001 | Nutr Cancer | pmid:12094634 |
Theander E et al. | Gammalinolenic acid treatment of fatigue associated with primary Sjögren's syndrome. | 2002 | Scand. J. Rheumatol. | pmid:12109650 |
Cohen SM et al. | Therapeutic use of selected herbs. | 2000 | Holist Nurs Pract | pmid:12119629 |
Harris NM et al. | Intravesical meglumine gamma-linolenic acid in superficial bladder cancer: an efficacy study. | 2002 | Eur. Urol. | pmid:12121728 |
Jack AM et al. | Effects of diabetes and evening primrose oil treatment on responses of aorta, corpus cavernosum and mesenteric vasculature in rats. | 2002 | Life Sci. | pmid:12175702 |
Hornych A et al. | The effect of gamma-linolenic acid on plasma and membrane lipids and renal prostaglandin synthesis in older subjects. | 2002 | Bratisl Lek Listy | pmid:12190041 |
Khunyoshyeng S et al. | Differential expression of desaturases and changes in fatty acid composition during sporangiospore germination and development in Mucor rouxii. | 2002 | Fungal Genet. Biol. | pmid:12223185 |
Hamburger M et al. | Constituents in evening primrose oil with radical scavenging, cyclooxygenase, and neutrophil elastase inhibitory activities. | 2002 | J. Agric. Food Chem. | pmid:12236675 |
Dyer O | Doctor accused of giving false information to drug trial. | 2002 | BMJ | pmid:12269314 |
Das UN | Abrupt and complete occlusion of tumor-feeding vessels by gamma-linolenic acid. | 2002 | Nutrition | pmid:12297217 |
Chung S et al. | Gamma-linolenic acid in borage oil reverses epidermal hyperproliferation in guinea pigs. | 2002 | J. Nutr. | pmid:12368400 |
Senanayake SP and Shahidi F | Positional distribution of FA in TAG of enzymatically modified borage and evening primrose oils. | 2002 | Lipids | pmid:12371752 |
Turon F et al. | A direct method for regiospecific analysis of TAG using alpha-MAG. | 2002 | Lipids | pmid:12371754 |
Gillis RC et al. | Eicosapentaenoic acid and gamma-linolenic acid induce apoptosis in HL-60 cells. | 2002 | J. Surg. Res. | pmid:12384078 |
Pérez Y et al. | Measurement by nuclear magnetic resonance diffusion of the dimensions of the mobile lipid compartment in C6 cells. | 2002 | Cancer Res. | pmid:12384523 |
Berry JA | Benign breast pain. New approaches manage this common condition more effectively. | 2001 | Adv Nurse Pract | pmid:12400335 |
Ernst E | Ayurvedic medicines. | 2002 | Pharmacoepidemiol Drug Saf | pmid:12426929 |
Uesaka Y | [Prevention and treatment of diabetic neuropathy]. | 2002 | Nippon Rinsho | pmid:12430238 |
Blommers J et al. | Evening primrose oil and fish oil for severe chronic mastalgia: a randomized, double-blind, controlled trial. | 2002 | Am. J. Obstet. Gynecol. | pmid:12439536 |
Leaver HA et al. | Highly unsaturated fatty acid induced tumour regression in glioma pharmacodynamics and bioavailability of gamma linolenic acid in an implantation glioma model: effects on tumour biomass, apoptosis and neuronal tissue histology. | 2002 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12445487 |
Pham H et al. | Activation of peroxisome proliferator-activated receptor (PPAR)-gamma by 15S-hydroxyeicosatrienoic acid parallels growth suppression of androgen-dependent prostatic adenocarcinoma cells. | 2003 | Cancer Lett. | pmid:12445673 |
Funtikova NS et al. | [Synthesis of biologically active lipids by fungus Mucor lusitanicus 306D grown on media with various composition]. | 2002 Nov-Dec | Prikl. Biokhim. Mikrobiol. | pmid:12449793 |
SimoncÃkova P et al. | Comparison of the extrapancreatic action of gamma-linolenic acid and n-3 PUFAs in the high fat diet-induced insulin resistance [corrected]. | 2002 | Endocr Regul | pmid:12466014 |
Samuels R et al. | Hypocholesterolemic effect of spirulina in patients with hyperlipidemic nephrotic syndrome. | 2002 | J Med Food | pmid:12487756 |
Harris NM et al. | Epirubicin and meglumine gamma-linolenic acid: a logical choice of combination therapy for patients with superficial bladder carcinoma. | 2003 | Cancer | pmid:12491507 |
Shotton HR et al. | The effectiveness of treatments of diabetic autonomic neuropathy is not the same in autonomic nerves supplying different organs. | 2003 | Diabetes | pmid:12502507 |
Duttaroy AK et al. | Acyl-CoA thioesterase activity in human placental choriocarcinoma (BeWo), cells: effects of fatty acids. | 2003 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12538089 |
Gimeno RE et al. | Characterization of a heart-specific fatty acid transport protein. | 2003 | J. Biol. Chem. | pmid:12556534 |
Pacht ER et al. | Enteral nutrition with eicosapentaenoic acid, gamma-linolenic acid, and antioxidants reduces alveolar inflammatory mediators and protein influx in patients with acute respiratory distress syndrome. | 2003 | Crit. Care Med. | pmid:12576957 |
Xian M et al. | Production of gamma-linolenic acid by disrupted mycelia of Mortierella isabellina. | 2003 | Lett. Appl. Microbiol. | pmid:12581380 |
Halat KM and Dennehy CE | Botanicals and dietary supplements in diabetic peripheral neuropathy. | 2003 Jan-Feb | J Am Board Fam Pract | pmid:12583650 |
Pham H and Ziboh VA | 5 alpha-reductase-catalyzed conversion of testosterone to dihydrotestosterone is increased in prostatic adenocarcinoma cells: suppression by 15-lipoxygenase metabolites of gamma-linolenic and eicosapentaenoic acids. | 2002 | J. Steroid Biochem. Mol. Biol. | pmid:12589947 |
Rosenstein ED et al. | Pilot study of dietary fatty acid supplementation in the treatment of adult periodontitis. | 2003 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12591005 |