gamma-Linolenic acid
Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.
Cross Reference
Introduction
To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid
PubChem Associated disorders and diseases
What pathways are associated with gamma-Linolenic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with gamma-Linolenic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with gamma-Linolenic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
What genes are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
What common seen animal models are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with gamma-Linolenic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Singer P et al. | Benefit of an enteral diet enriched with eicosapentaenoic acid and gamma-linolenic acid in ventilated patients with acute lung injury. | 2006 | Crit. Care Med. | pmid:16484911 |
| Das UN and Rao KP | Effect of gamma-linolenic acid and prostaglandins E1 on gamma-radiation and chemical-induced genetic damage to the bone marrow cells of mice. | 2006 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:16488586 |
| Noli C et al. | Conjugated linoleic acid and black currant seed oil in the treatment of canine atopic dermatitis: a preliminary report. | 2007 | Vet. J. | pmid:16495095 |
| Gardiner NS and Duncan JR | Possible involvement of delta-6-desaturase in control of melanoma growth by gamma-linolenic acid. | 1991 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:1650000 |
| Martin TA et al. | Synergistic regulation of endothelial tight junctions by antioxidant (Se) and polyunsaturated lipid (GLA) via Claudin-5 modulation. | 2006 | J. Cell. Biochem. | pmid:16514648 |
| Gasperino J and Kvetan V | Acute lung injury and nutritional support. | 2006 | Crit. Care Med. | pmid:16550085 |
| Chapkin RS and Coble KJ | Utilization of gammalinolenic acid by mouse peritoneal macrophages. | 1991 | Biochim. Biophys. Acta | pmid:1655039 |
| Pham H et al. | Dietary gamma-linolenate attenuates tumor growth in a rodent model of prostatic adenocarcinoma via suppression of elevated generation of PGE(2) and 5S-HETE. | 2006 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:16567086 |
| Ulmann L et al. | Incorporation into liver microsomal lipids of linoleic and stearic acids and of their respective products of delta 6 and delta 9 desaturation, gamma-linolenic and oleic acids: effect of age and of blackcurrant seed oil. | 1991 | Biochim. Biophys. Acta | pmid:1657182 |
| Beck SA et al. | Anticachectic and antitumor effect of eicosapentaenoic acid and its effect on protein turnover. | 1991 | Cancer Res. | pmid:1657378 |
| Hongsthong A et al. | Revealing the complementation of ferredoxin by cytochrome b (5) in the Spirulina- (6)-desaturation reaction by N-terminal fusion and co-expression of the fungal-cytochrome b (5) domain and Spirulina- (6)-acyl-lipid desaturase. | 2006 | Appl. Microbiol. Biotechnol. | pmid:16575563 |
| Kitz R et al. | Impact of early dietary gamma-linolenic acid supplementation on atopic eczema in infancy. | 2006 | Pediatr Allergy Immunol | pmid:16618360 |
| Izumi T et al. | Purification of two forms of arachidonate 15-lipoxygenase from human leukocytes. | 1991 | Eur. J. Biochem. | pmid:1662607 |
| Tocher DR et al. | Effect of diets enriched in Delta6 desaturated fatty acids (18:3n-6 and 18:4n-3), on growth, fatty acid composition and highly unsaturated fatty acid synthesis in two populations of Arctic charr (Salvelinus alpinus L.). | 2006 | Comp. Biochem. Physiol. B, Biochem. Mol. Biol. | pmid:16630735 |
| Julu PO and Mutamba A | Comparison of short-term effects of insulin and essential fatty acids on the slowed nerve conduction of streptozotocin diabetes in rats. | 1991 | J. Neurol. Sci. | pmid:1663993 |
| Azevedo-Martins AK et al. | Fatty acid-induced toxicity and neutral lipid accumulation in insulin-producing RINm5F cells. | 2006 | Toxicol In Vitro | pmid:16644178 |
| Freeman MS et al. | The effects of essential fatty acid supplementation on lithium absorption kinetics in guinea pig jejunum. | 1991 | Biochem. Soc. Trans. | pmid:1665438 |
| Melnik B and Plewig G | Atopic dermatitis and disturbances of essential fatty acid and prostaglandin E metabolism. | 1991 | J. Am. Acad. Dermatol. | pmid:1666398 |
| Gilani S et al. | Chick embryonic development following exposure to ethanol, gamma-linolenic and linolenic acids. | 1991 | Anat Anz | pmid:1666823 |
| KristofÃková L et al. | Selection of Rhizopus strains for L(+)-lactic acid and gamma-linolenic acid production. | 1991 | Folia Microbiol. (Praha) | pmid:1668279 |
| Das UN | Re: Effect of gamma-linolenic acid on the transcriptional activity of the Her-2/neu (erbB-2) oncogene. | 2006 | J. Natl. Cancer Inst. | pmid:16705127 |
| Biagi PL et al. | Gamma-linolenic acid dietary supplementation can reverse the aging influence on rat liver microsome delta 6-desaturase activity. | 1991 | Biochim. Biophys. Acta | pmid:1674661 |
| Chen YC et al. | Therapeutic effect of topical gamma-linolenic acid on refractory uremic pruritus. | 2006 | Am. J. Kidney Dis. | pmid:16797388 |
| Miles EA et al. | Self-reported health problems in young male subjects supplementing their diet with oils rich in eicosapentaenoic, gamma-linolenic and stearidonic acids. | 2006 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:16820286 |
| Pontes-Arruda A et al. | Effects of enteral feeding with eicosapentaenoic acid, gamma-linolenic acid, and antioxidants in mechanically ventilated patients with severe sepsis and septic shock. | 2006 | Crit. Care Med. | pmid:16850002 |
| Fakas S et al. | Lipids of Cunninghamella echinulata with emphasis to gamma-linolenic acid distribution among lipid classes. | 2006 | Appl. Microbiol. Biotechnol. | pmid:16850299 |
| Kong X et al. | Induction of apoptosis in K562/ADM cells by gamma-linolenic acid involves lipid peroxidation and activation of caspase-3. | 2006 | Chem. Biol. Interact. | pmid:16857180 |
| Pacht ER | Enteral therapy to decrease morbidity and improve survival in acute respiratory distress syndrome: its time has come. | 2006 | Crit. Care Med. | pmid:16921322 |
| Puri BK | Long-chain polyunsaturated fatty acids and the pathophysiology of myalgic encephalomyelitis (chronic fatigue syndrome). | 2007 | J. Clin. Pathol. | pmid:16935966 |
| Umeda-Sawada R et al. | Distribution and metabolism of dihomo-gamma-linolenic acid (DGLA, 20:3n-6) by oral supplementation in rats. | 2006 | Biosci. Biotechnol. Biochem. | pmid:16960355 |
| Kim J et al. | Comparative effect of gromwell (Lithospermum erythrorhizon) extract and borage oil on reversing epidermal hyperproliferation in guinea pigs. | 2006 | Biosci. Biotechnol. Biochem. | pmid:16960390 |
| Hatanaka E et al. | Systematic study on ROS production induced by oleic, linoleic, and gamma-linolenic acids in human and rat neutrophils. | 2006 | Free Radic. Biol. Med. | pmid:16962937 |
| Matta JA et al. | TRPV1 is a novel target for omega-3 polyunsaturated fatty acids. | 2007 | J. Physiol. (Lond.) | pmid:17038422 |
| Arab K et al. | Conjugated linoleic acid, unlike other unsaturated fatty acids, strongly induces glutathione synthesis without any lipoperoxidation. | 2006 | Br. J. Nutr. | pmid:17092368 |
| Kim JJ et al. | Properties of cholesterol-reduced butter made with beta-cyclodextrin and added evening primrose oil and phytosterols. | 2006 | J. Dairy Sci. | pmid:17106080 |
| DeMichele SJ et al. | A nutritional strategy to improve oxygenation and decrease morbidity in patients who have acute respiratory distress syndrome. | 2006 | Respir Care Clin N Am | pmid:17150431 |
| Sýkora J et al. | High-performance liquid chromatography with nuclear magnetic resonance detection--A method for quantification of alpha- and gamma-linolenic acids in their mixtures with free fatty acids. | 2007 | J Chromatogr A | pmid:17157864 |
| Das UN | Tumoricidal and anti-angiogenic actions of gamma-linolenic acid and its derivatives. | 2006 | Curr Pharm Biotechnol | pmid:17168663 |
| Morse NL and Clough PM | A meta-analysis of randomized, placebo-controlled clinical trials of Efamol evening primrose oil in atopic eczema. Where do we go from here in light of more recent discoveries? | 2006 | Curr Pharm Biotechnol | pmid:17168667 |
| Kapoor R and Huang YS | Gamma linolenic acid: an antiinflammatory omega-6 fatty acid. | 2006 | Curr Pharm Biotechnol | pmid:17168669 |
| Pitel S et al. | At low doses, a gamma-linolenic acid-lipoic acid conjugate is more effective than docosahexaenoic acid-enriched phospholipids in preventing neuropathy in diabetic rats. | 2007 | J. Nutr. | pmid:17237313 |
| Martin TA et al. | Enhanced tight junction function in human breast cancer cells by antioxidant, selenium and polyunsaturated lipid. | 2007 | J. Cell. Biochem. | pmid:17243118 |
| Garaiova I et al. | A randomised cross-over trial in healthy adults indicating improved absorption of omega-3 fatty acids by pre-emulsification. | 2007 | Nutr J | pmid:17254329 |
| Pinna A et al. | Effect of oral linoleic and gamma-linolenic acid on meibomian gland dysfunction. | 2007 | Cornea | pmid:17413949 |
| Curtis L | High-quality enteral nutrition essential for reducing morbidity and mortality in acute care patients. | 2007 | Crit. Care Med. | pmid:17421112 |
| Ortiz-Leyba C and Garnacho-Montero J | Saving lives in severe sepsis with the help of enteral nutrition. | 2007 | Crit. Care Med. | pmid:17421113 |
| Lu H et al. | [Cloning and expression of a delta6-fatty acid desaturase gene from Rhizopus stolonifer in Saccharomyces cervisiae]. | 2007 | Wei Sheng Wu Xue Bao | pmid:17436625 |
| Schirmer MA and Phinney SD | Gamma-linolenate reduces weight regain in formerly obese humans. | 2007 | J. Nutr. | pmid:17513402 |
| Das UN | Gamma-linolenic acid therapy of human glioma-a review of in vitro, in vivo, and clinical studies. | 2007 | Med. Sci. Monit. | pmid:17599036 |
| Kanehara S et al. | Undershirts coated with borage oil alleviate the symptoms of atopic dermatitis in children. | 2007 Sep-Oct | Eur J Dermatol | pmid:17673396 |