gamma-Linolenic acid

Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.

Cross Reference

Introduction

To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Alcoholism D000437 27 associated lipids
Arteriosclerosis D001161 86 associated lipids
Ascorbic Acid Deficiency D001206 9 associated lipids
Back Pain D001416 5 associated lipids
Bacteriuria D001437 7 associated lipids
Body Weight D001835 333 associated lipids
Carcinoma 256, Walker D002279 22 associated lipids
Cardiovascular Diseases D002318 24 associated lipids
Carpal Tunnel Syndrome D002349 3 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Dermatitis D003872 30 associated lipids
Dermatitis, Atopic D003876 19 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Dyskinesia, Drug-Induced D004409 15 associated lipids
Dysmenorrhea D004412 9 associated lipids
Ecchymosis D004438 3 associated lipids
Encephalomyelitis, Autoimmune, Experimental D004681 26 associated lipids
Fallopian Tube Neoplasms D005185 1 associated lipids
Fatigue D005221 10 associated lipids
Fibrocystic Breast Disease D005348 1 associated lipids
Food Hypersensitivity D005512 7 associated lipids
Gastritis D005756 27 associated lipids
Gastritis, Atrophic D005757 4 associated lipids
Glioma D005910 112 associated lipids
Hand Dermatoses D006229 5 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Hyperlipidemias D006949 73 associated lipids
Hyperplasia D006965 34 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Hypertension D006973 115 associated lipids
Erectile Dysfunction D007172 19 associated lipids
Inflammation D007249 119 associated lipids
Insulin Resistance D007333 99 associated lipids
Intermittent Claudication D007383 6 associated lipids
Kidney Calculi D007669 7 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Leukemia P388 D007941 43 associated lipids
Liver Cirrhosis, Alcoholic D008104 17 associated lipids
Lung Neoplasms D008175 171 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Melanoma D008545 69 associated lipids
Mucocele D009078 1 associated lipids
Nausea D009325 7 associated lipids
Per page 10 20 50 100 | Total 85

PubChem Associated disorders and diseases

What pathways are associated with gamma-Linolenic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with gamma-Linolenic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with gamma-Linolenic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with gamma-Linolenic acid

Download all related citations
Per page 10 20 50 100 | Total 1121
Authors Title Published Journal PubMed Link
Fuller MA et al. Activity of soybean lipoxygenase isoforms against esterified fatty acids indicates functional specificity. 2001 Arch. Biochem. Biophys. pmid:11361131
Barre DE Potential of evening primrose, borage, black currant, and fungal oils in human health. 2001 Ann. Nutr. Metab. pmid:11359029
Hounsom L et al. Oxidative stress participates in the breakdown of neuronal phenotype in experimental diabetic neuropathy. 2001 Diabetologia pmid:11357471
Hrelia S et al. Role of gamma-linolenic acid in counteracting doxorubicin-induced damage in cultured rat cardiomyocytes. 2001 Prostaglandins Leukot. Essent. Fatty Acids pmid:11334548
Colquhoun A and Schumacher RI Modifications in mitochondrial metabolism and ultrastructure and their relationship to tumour growth inhibition by gamma-linolenic acid. 2001 Mol. Cell. Biochem. pmid:11330827
Mpanju O et al. Selective cytotoxicity of lithium gamma-linolenic acid in human T cells chronically and productively infected with HIV. 1997 Antivir. Ther. (Lond.) pmid:11322262
Fauconnot L and Buist PH Gamma-linolenic acid biosynthesis: cryptoregiochemistry of delta6 desaturation. 2001 J. Org. Chem. pmid:11312950
Sims EC and Plowman PN Stereotactic radiosurgery XII. Large AVM and the failure of the radiation response modifier gamma linolenic acid to improve the therapeutic ratio. 2001 Br J Neurosurg pmid:11303657
Kaku S et al. Interactions of dietary fats and proteins on fatty acid composition of immune cells and LTB4 production by peritoneal exudate cells of rats. 2001 Biosci. Biotechnol. Biochem. pmid:11302164
Kenny FS et al. Effect of dietary GLA+/-tamoxifen on the growth, ER expression and fatty acid profile of ER positive human breast cancer xenografts. 2001 Int. J. Cancer pmid:11291069
Little C and Parsons T Herbal therapy for treating rheumatoid arthritis. 2001 Cochrane Database Syst Rev pmid:11279784
Keysser G [Are there effective dietary recommendations for patients with rheumatoid arthritis?]. 2001 Z Rheumatol pmid:11263011
Borenshtein D et al. Cataract development in diabetic sand rats treated with alpha-lipoic acid and its gamma-linolenic acid conjugate. 2001 Jan-Feb Diabetes Metab. Res. Rev. pmid:11241890
Menéndez JA et al. Effects of gamma-linolenic acid and oleic acid on paclitaxel cytotoxicity in human breast cancer cells. 2001 Eur. J. Cancer pmid:11239764
Thies F et al. Dietary supplementation with eicosapentaenoic acid, but not with other long-chain n-3 or n-6 polyunsaturated fatty acids, decreases natural killer cell activity in healthy subjects aged >55 y. 2001 Am. J. Clin. Nutr. pmid:11237929
Agostoni C et al. Biochemical effects of supplemented long-chain polyunsaturated fatty acids in hyperphenylalaninemia. 2001 Prostaglandins Leukot. Essent. Fatty Acids pmid:11237478
Shahidi F Antioxidant factors in plant foods and selected oilseeds. 2000 Biofactors pmid:11237180
Khamaisi M et al. Metabolic effects of gamma-linolenic acid-alpha-lipoic acid conjugate in streptozotocin diabetic rats. 1999 Antioxid. Redox Signal. pmid:11233149
Corbett JW et al. Trifluoromethyl-containing 3-alkoxymethyl- and 3-aryloxymethyl-2-pyridinones are potent inhibitors of HIV-1 non-nucleoside reverse transcriptase. 2001 Bioorg. Med. Chem. Lett. pmid:11212098
Olguín EJ et al. The effect of low light flux and nitrogen deficiency on the chemical composition of Spirulina sp. (Arthrospira) grown on digested pig waste. 2001 Bioresour. Technol. pmid:11211071
Frenoux JM et al. A polyunsaturated fatty acid diet lowers blood pressure and improves antioxidant status in spontaneously hypertensive rats. 2001 J. Nutr. pmid:11208936
Conti E et al. gamma-Linolenic acid production by solid-state fermentation of Mucorales strains on cereals. 2001 Bioresour. Technol. pmid:11198184
Beaudoin F et al. Production of C20 polyunsaturated fatty acids (PUFAs) by pathway engineering: identification of a PUFA elongase component from Caenorhabditis elegans. 2000 Biochem. Soc. Trans. pmid:11171161
Dobson G Leaf lipids of Ribes nigrum: a plant containing 16:3, alpha-18:3, gamma-18:3 and 18:4 fatty acids. 2000 Biochem. Soc. Trans. pmid:11171133
Goffman FD and Galletti S Gamma-linolenic acid and tocopherol contents in the seed oil of 47 accessions from several Ribes species. 2001 J. Agric. Food Chem. pmid:11170598
Ito Y et al. Effects of polyunsaturated fatty acids on atrophic gastritis in a Japanese population. 2001 Cancer Lett. pmid:11165751
Kankaanpää PE et al. The influence of polyunsaturated fatty acids on probiotic growth and adhesion. 2001 FEMS Microbiol. Lett. pmid:11164299
Biessels GJ et al. The effect of gamma-linolenic acid-alpha-lipoic acid on functional deficits in the peripheral and central nervous system of streptozotocin-diabetic rats. 2001 J. Neurol. Sci. pmid:11137514
Harbige LS et al. The protective effects of omega-6 fatty acids in experimental autoimmune encephalomyelitis (EAE) in relation to transforming growth factor-beta 1 (TGF-beta1) up-regulation and increased prostaglandin E2 (PGE2) production. 2000 Clin. Exp. Immunol. pmid:11122253
Horner NK and Lampe JW Potential mechanisms of diet therapy for fibrocystic breast conditions show inadequate evidence of effectiveness. 2000 J Am Diet Assoc pmid:11103660
Worm M and Henz BM Novel unconventional therapeutic approaches to atopic eczema. 2000 Dermatology (Basel) pmid:11096188
Fokkema MR et al. Short-term supplementation of low-dose gamma-linolenic acid (GLA), alpha-linolenic acid (ALA), or GLA plus ALA does not augment LCP omega 3 status of Dutch vegans to an appreciable extent. 2000 Prostaglandins Leukot. Essent. Fatty Acids pmid:11090255
Takahashi Y et al. Dietary gamma-linolenic acid in the form of borage oil causes less body fat accumulation accompanying an increase in uncoupling protein 1 mRNA level in brown adipose tissue. 2000 Comp. Biochem. Physiol. B, Biochem. Mol. Biol. pmid:11079375
Chan LW et al. Microencapsulation of oils using sodium alginate. 2000 Nov-Dec J Microencapsul pmid:11063422
Pakala R et al. Vascular smooth muscle cells preloaded with eicosapentaenoic acid and docosahexaenoic acid fail to respond to serotonin stimulation. 2000 Atherosclerosis pmid:11058699
Palombo JD et al. Comparison of growth and fatty acid metabolism in rats fed diets containing equal levels of gamma-linolenic acid from high gamma-linolenic acid canola oil or borage oil. 2000 Lipids pmid:11026618
Petrik MB et al. Highly unsaturated (n-3) fatty acids, but not alpha-linolenic, conjugated linoleic or gamma-linolenic acids, reduce tumorigenesis in Apc(Min/+) mice. 2000 J. Nutr. pmid:11015469
Iijima S et al. Oral supplementation with gamma-linolenic acid extracted from Mucor circinelloides improves the deformability of red blood cells in hemodialysis patients. 2000 Nephron pmid:11014980
Oakley OR et al. The effects of lithium gamma-linolenic acid in reversing LPBM5 MuLV induced suppression of hematopoietic progenitor cells in vitro. 1998 Jan-Jun Rom J Physiol pmid:11000861
Vinik AI et al. Diabetic neuropathies. 2000 Diabetologia pmid:10990072
Liu QY and Tan BK Effects of cis-unsaturated fatty acids on doxorubicin sensitivity in P388/DOX resistant and P388 parental cell lines. 2000 Life Sci. pmid:10954054
Guil-Guerrero JL et al. Occurrence and characterization of oils rich in gamma-linolenic acid part II: fatty acids and squalene from Macaronesian Echium leaves. 2000 Phytochemistry pmid:10939357
Arnold LE et al. Does zinc moderate essential fatty acid and amphetamine treatment of attention-deficit/hyperactivity disorder? 2000 J Child Adolesc Psychopharmacol pmid:10933121
Barham JB et al. Addition of eicosapentaenoic acid to gamma-linolenic acid-supplemented diets prevents serum arachidonic acid accumulation in humans. 2000 J. Nutr. pmid:10917903
Rahbeeni F et al. The effect of evening primrose oil on the radiation response and blood flow of mouse normal and tumour tissue. 2000 Int. J. Radiat. Biol. pmid:10902742
Parker-Barnes JM et al. Identification and characterization of an enzyme involved in the elongation of n-6 and n-3 polyunsaturated fatty acids. 2000 Proc. Natl. Acad. Sci. U.S.A. pmid:10899997
Oguogho A et al. Prostaglandin synthesis in human lymphatics from precursor fatty acids. 2000 Lymphology pmid:10897472
Kapoor R and Klimaszewski A Efficacy of borage oil in patients with atopic eczema. 2000 Br. J. Dermatol. pmid:10886164
Kumar KV et al. Oxidant stress and essential fatty acids in patients with risk and established ARDS. 2000 Clin. Chim. Acta pmid:10876008
Murray MJ et al. Effects of eicosapentaenoic and gamma-linolenic acids (dietary lipids) on pulmonary surfactant composition and function during porcine endotoxemia. 2000 Chest pmid:10858408