Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.
To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Segarnick DJ et al. | Gamma-linolenic acid inhibits the development of the ethanol-induced fatty liver. | 1985 | Prostaglandins Leukot Med | pmid:2986177 |
Botha JH et al. | The response of human carcinoma cell lines to gamma-linolenic acid with special reference to the effects of agents which influence prostaglandin and thromboxane synthesis. | 1985 | Prostaglandins Leukot Med | pmid:2994114 |
Segarnick DJ et al. | Prostanoid modulation (mediation?) of certain behavioral effects of ethanol. | 1985 | Pharmacol. Biochem. Behav. | pmid:2994122 |
Das UN et al. | Prostaglandins and their precursors can modify genetic damage-induced by gamma-radiation and benzo(a)pyrene. | 1985 | Prostaglandins | pmid:2994175 |
de Bravo MM et al. | Metabolism of gammalinolenic acid by human blood platelet microsomes. | 1985 | Biochem. Int. | pmid:2994669 |
Mills DE et al. | Gamma linolenic acid attenuates cardiovascular responses to stress in borderline hypertensive rats. | 1985 | Lipids | pmid:2995750 |
Booyens J et al. | The use of drugs for the inhibition of prostaglandin or leukotriene synthesis from arachidonic acid is theoretically hazardous. | 1985 | Med. Hypotheses | pmid:2995775 |
Wainwright P et al. | gamma-Linolenic acid fails to prevent the effects of prenatal ethanol exposure on brain and behavioral development in B6D2F2 mice. | 1985 Jul-Aug | Alcohol. Clin. Exp. Res. | pmid:2996378 |
Robinson KM and Botha JH | Effects of gamma-linolenic acid, dihomo-gamma-linolenic acid and ethanol on cultured human mammary carcinoma cells. | 1985 | Prostaglandins Leukot Med | pmid:2999828 |
Wolkin A et al. | Essential fatty acid supplementation in tardive dyskinesia. | 1986 | Am J Psychiatry | pmid:3013033 |
Skogh M | Atopic eczema unresponsive to evening primrose oil (linoleic and gamma-linolenic acids) | 1986 | J. Am. Acad. Dermatol. | pmid:3013957 |
Bégin ME and Das UN | A deficiency in dietary gamma-linolenic and/or eicosapentaenoic acids may determine individual susceptibility to AIDS. | 1986 | Med. Hypotheses | pmid:3014282 |
Fujiwara F et al. | Antitumor effect of gamma-linolenic acid on cultured human neuroblastoma cells. | 1986 | Prostaglandins Leukot Med | pmid:3020590 |
Dib A and Carreau JP | Effects of gamma-linolenic acid supplementation on lipogenesis regulation in pregnant zinc-deficient rat and fetus. | 1986 | Int. J. Biochem. | pmid:3026865 |
Stymne S and Stobart AK | Biosynthesis of gamma-linolenic acid in cotyledons and microsomal preparations of the developing seeds of common borage (Borago officinalis). | 1986 | Biochem. J. | pmid:3028375 |
Viikari J and Lehtonen A | Effect of primrose oil on serum lipids and blood pressure in hyperlipidemic subjects. | 1986 | Int J Clin Pharmacol Ther Toxicol | pmid:3028968 |
Bursztyn PG and King MH | Fat induced hypertension in rabbits: the effects of dietary linoleic and linolenic acid. | 1986 | J. Hypertens. | pmid:3029216 |
Huang YS et al. | Protective effect of gamma-linolenic acid on aspirin-induced gastric hemorrhage in rats. | 1987 | Digestion | pmid:3030865 |
Horrobin DF | Essential fatty acids, prostaglandins, and alcoholism: an overview. | 1987 | Alcohol. Clin. Exp. Res. | pmid:3032012 |
Cunnane SC | Hepatic triacylglycerol accumulation induced by ethanol and carbon tetrachloride: interactions with essential fatty acids and prostaglandins. | 1987 | Alcohol. Clin. Exp. Res. | pmid:3032013 |
Nassar BA et al. | The influence of dietary marine oil (Polepa) and evening primrose oil (Efamol) on prostaglandin production by the rat mesenteric vasculature. | 1987 | Prostaglandins Leukot Med | pmid:3033691 |
McIllmurray MB and Turkie W | Controlled trial of gamma linolenic acid in Duke's C colorectal cancer. | 1987 | Br Med J (Clin Res Ed) | pmid:3036291 |
Huang YS and Horrobin DF | Sex differences in n-3 and n-6 fatty acid metabolism in EFA-depleted rats. | 1987 | Proc. Soc. Exp. Biol. Med. | pmid:3037555 |
Biagi PL et al. | A long-term study on the use of evening primrose oil (Efamol) in atopic children. | 1988 | Drugs Exp Clin Res | pmid:3048952 |
Bordoni A et al. | Evening primrose oil (Efamol) in the treatment of children with atopic eczema. | 1988 | Drugs Exp Clin Res | pmid:3048953 |
van Doormaal JJ et al. | Effects of short-term high dose intake of evening primrose oil on plasma and cellular fatty acid compositions, alpha-tocopherol levels, and erythropoiesis in normal and type 1 (insulin-dependent) diabetic men. | 1988 | Diabetologia | pmid:3065111 |
Simpson LO | Pinch skin grafting or porcine dermis in venous ulcers. | 1987 | Br Med J (Clin Res Ed) | pmid:3109651 |
el-Ela SH et al. | Effects of dietary primrose oil on mammary tumorigenesis induced by 7,12-dimethylbenz(a)anthracene. | 1987 | Lipids | pmid:3131611 |
Abou-el-Ela SH et al. | Eicosanoid synthesis in 7,12-dimethylbenz(a)anthracene-induced mammary carcinomas in Sprague-Dawley rats fed primrose oil, menhaden oil or corn oil diet. | 1988 | Lipids | pmid:3143882 |
Wade AE et al. | Effect of 7,12-dimethylbenz(a)anthracene administration on hepatic drug metabolizing enzymes in female rats fed corn, primrose, and menhaden oils. | 1988 | Drug Nutr Interact | pmid:3149238 |
Barcelli UO et al. | A diet containing n-3 and n-6 fatty acids favorably alters the renal phospholipids, eicosanoid synthesis and plasma lipids in nephrotic rats. | 1988 | Lipids | pmid:3237005 |
Darlington LG | Do diets rich in polyunsaturated fatty acids affect disease activity in rheumatoid arthritis? | 1988 | Ann. Rheum. Dis. | pmid:3281607 |
Manthorpe R and Prause JU | Treatment of Sjögren's syndrome: an overview. | 1986 | Scand. J. Rheumatol. Suppl. | pmid:3296150 |
Horrobin DF | Essential fatty acid and prostaglandin metabolism in Sjögren's syndrome, systemic sclerosis and rheumatoid arthritis. | 1986 | Scand. J. Rheumatol. Suppl. | pmid:3296151 |
Schalin-Karrila M et al. | Evening primrose oil in the treatment of atopic eczema: effect on clinical status, plasma phospholipid fatty acids and circulating blood prostaglandins. | 1987 | Br. J. Dermatol. | pmid:3307886 |
Greaves MW and Corbett MF | Treatment of atopic eczema with evening primrose oil. | 1988 | Br. J. Dermatol. | pmid:3355786 |
Novak E | Maintaining remission of Crohn's disease. | 1988 | CMAJ | pmid:3383034 |
Morrison CS | Leg ulceration and Efamol. | 1986 | N. Z. Med. J. | pmid:3463912 |
Simpson LO | Leg ulceration and Efamol. | 1986 | N. Z. Med. J. | pmid:3466083 |
Morrison CS | Leg ulcers and Efamol. | 1986 | N. Z. Med. J. | pmid:3468432 |
Papanikolaou N | Alteration of mercuric chloride-induced autoimmune glomerulonephritis in brown-Norway rats by herring oil, evening primrose oil and OKY-046 a selective TXA-synthetase inhibitor. | 1987 | Prostaglandins Leukot Med | pmid:3475724 |
Godfrey DG et al. | Effects of dietary supplementation on autoimmunity in the MRL/lpr mouse: a preliminary investigation. | 1986 | Ann. Rheum. Dis. | pmid:3492970 |
Singer P et al. | Serum triglycerides and HDL cholesterol from SHR after evening primrose oil and other polyunsaturated fats. | 1986 | Prostaglandins Leukot Med | pmid:3523538 |
Ferrando J | [Clinical trial of a topical preparation containing urea, sunflower oil, evening primrose oil, wheat germ oil and sodium pyruvate, in several hyperkeratotic skin conditions]. | 1986 | Med Cutan Ibero Lat Am | pmid:3528709 |
Oxholm P et al. | Patients with primary Sjögren's syndrome treated for two months with evening primrose oil. | 1986 | Scand. J. Rheumatol. | pmid:3529370 |
Glen I et al. | The role of essential fatty acids in alcohol dependence and tissue damage. | 1987 | Alcohol. Clin. Exp. Res. | pmid:3551662 |
Bordoni A et al. | [Treatment of premenstrual syndrome with essential fatty acids (evening primrose oil)]. | 1987 | G Clin Med | pmid:3609594 |
Chapkin RS et al. | Dietary influences of evening primrose and fish oil on the skin of essential fatty acid-deficient guinea pigs. | 1987 | J. Nutr. | pmid:3625311 |
Takahashi R et al. | Effect of different ratios of dietary N-6 and N-3 fatty acids on fatty acid composition, prostaglandin formation and platelet aggregation in the rat. | 1987 | Thromb. Res. | pmid:3660347 |
Papanikolaou N et al. | Effect of thromboxane A2-synthetase inhibitor OKY-046 and evening primrose oil (Efamol) on mercuric chloride induced autoimmune glomerulonephritis in Brown-Norway rats. | 1987 | Prog. Clin. Biol. Res. | pmid:3671393 |