gamma-Linolenic acid

Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.

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Introduction

To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid

MeSH term MeSH ID Detail
Stomach Ulcer D013276 75 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Adenocarcinoma D000230 166 associated lipids
Pain D010146 64 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Lung Neoplasms D008175 171 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Inflammation D007249 119 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Body Weight D001835 333 associated lipids
Gastritis D005756 27 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Osteosarcoma D012516 50 associated lipids
Melanoma D008545 69 associated lipids
Kidney Calculi D007669 7 associated lipids
Weight Gain D015430 101 associated lipids
Cardiovascular Diseases D002318 24 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Glioma D005910 112 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Leukemia P388 D007941 43 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Thrombosis D013927 49 associated lipids
Hyperplasia D006965 34 associated lipids
Arteriosclerosis D001161 86 associated lipids
Neuroblastoma D009447 66 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Psoriasis D011565 47 associated lipids
Alcoholism D000437 27 associated lipids
Bacteriuria D001437 7 associated lipids
Respiratory Insufficiency D012131 10 associated lipids
Erectile Dysfunction D007172 19 associated lipids
Liver Cirrhosis, Alcoholic D008104 17 associated lipids
Respiratory Distress Syndrome, Adult D012128 15 associated lipids
Seizures D012640 87 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Hypertension D006973 115 associated lipids
Dermatitis D003872 30 associated lipids
Leukemia, Myeloid, Acute D015470 19 associated lipids
Neoplasms, Hormone-Dependent D009376 23 associated lipids
Dermatitis, Seborrheic D012628 10 associated lipids
Hyperlipidemias D006949 73 associated lipids
Encephalomyelitis, Autoimmune, Experimental D004681 26 associated lipids
Dermatitis, Atopic D003876 19 associated lipids
Premenstrual Syndrome D011293 7 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with gamma-Linolenic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with gamma-Linolenic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with gamma-Linolenic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with gamma-Linolenic acid

Download all related citations
Per page 10 20 50 100 | Total 1121
Authors Title Published Journal PubMed Link
Ziboh VA and Fletcher MP Dose-response effects of dietary gamma-linolenic acid-enriched oils on human polymorphonuclear-neutrophil biosynthesis of leukotriene B4. 1992 Am. J. Clin. Nutr. pmid:1309474
Mimouni V et al. Evidence for insulin dependent hepatic microsomal gamma-linolenic acid chain elongation in spontaneously diabetic Wistar BB rats. 1992 Biochim. Biophys. Acta pmid:1310052
St Louis C et al. Antihypertensive effect of gamma-linolenic acid in spontaneously hypertensive rats. 1992 Hypertension pmid:1310479
Lockett MJ and Tomlinson DR The effects of dietary treatment with essential fatty acids on sciatic nerve conduction and activity of the Na+/K+ pump in streptozotocin-diabetic rats. 1992 Br. J. Pharmacol. pmid:1313726
Van Biervliet JP et al. Serum cholesterol, cholesteryl ester, and high-density lipoprotein development in newborn infants: response to formulas supplemented with cholesterol and gamma-linolenic acid. 1992 J. Pediatr. pmid:1313864
de Kock M et al. Effects of gamma-linolenic acid on mitosis and nuclear morphology in osteogenic sarcoma cells. 1992 S. Afr. Med. J. pmid:1315459
Bégin ME and Ells G Levels of thiobarbituric acid reactive substances and the cytocidal potential of gammalinolenic and docosahexaenoic acids on ZR-75-1 and CV-1 cells. 1992 Lipids pmid:1315901
Duffy O et al. Effects of an oil enriched in gamma linolenic acid on locomotor activity and behaviour in the Morris Maze, following in utero ethanol exposure in rats. 1992 Drug Alcohol Depend pmid:1317288
Kerscher MJ and Korting HC Treatment of atopic eczema with evening primrose oil: rationale and clinical results. 1992 Clin Investig pmid:1318129
Gibson RA et al. Gamma linolenic acid (GLA) content of encapsulated evening primrose oil products. 1992 Lipids pmid:1318991
Vaddadi KS Use of gamma-linolenic acid in the treatment of schizophrenia and tardive dyskinesia. 1992 Prostaglandins Leukot. Essent. Fatty Acids pmid:1321448
Horrobin DF The relationship between schizophrenia and essential fatty acid and eicosanoid metabolism. 1992 Prostaglandins Leukot. Essent. Fatty Acids pmid:1321449
Navarette R et al. Dietary intake of concentrated gamma-linolenic acid (GLA)-enriched oil suppresses cutaneous level of dihomo-gamma-linolenic acid (DGLA): possible in vivo inhibition of microsomal elongation of GLA to DGLA. 1992 Prostaglandins Leukot. Essent. Fatty Acids pmid:1323857
Scott DW et al. Comparison of the clinical efficacy of two commercial fatty acid supplements (EfaVet and DVM Derm Caps), evening primrose oil, and cold water marine fish oil in the management of allergic pruritus in dogs: a double-blinded study. 1992 Cornell Vet pmid:1643883
Gateley CA et al. Drug treatments for mastalgia: 17 years experience in the Cardiff Mastalgia Clinic. 1992 J R Soc Med pmid:1548647
Hamberg M Metabolism of 6,9,12-octadecatrienoic acid in the red alga Lithothamnion corallioides: mechanism of formation of a conjugated tetraene fatty acid. 1992 Biochem. Biophys. Res. Commun. pmid:1332713
Gunstone FD Gamma linolenic acid--occurrence and physical and chemical properties. 1992 Prog. Lipid Res. pmid:1334265
Horrobin DF Nutritional and medical importance of gamma-linolenic acid. 1992 Prog. Lipid Res. pmid:1334266
Engler MM et al. Dietary gamma-linolenic acid lowers blood pressure and alters aortic reactivity and cholesterol metabolism in hypertension. 1992 J. Hypertens. pmid:1335001
McFayden IJ et al. Cyclical breast pain--some observations and the difficulties in treatment. 1992 Br J Clin Pract pmid:1286012
Hayashi Y et al. Anticancer effects of free polyunsaturated fatty acids in an oily lymphographic agent following intrahepatic arterial administration to a rabbit bearing VX-2 tumor. 1992 Cancer Res. pmid:1309442
Dobbin SN Evening primrose oil and epilepsy. 1992 Dec 19-26 Vet. Rec. pmid:1287960
Takeda S et al. Lipid peroxidation in human breast cancer cells in response to gamma-linolenic acid and iron. 1992 Mar-Apr Anticancer Res. pmid:1316091
Söreide E et al. Long-term use of gamma-linolenic acid-enriched fat emulsion (PFE 4501): case report. 1992 May-Jun Nutrition pmid:1326350
Cantrill RC et al. The effect of n-6 fatty acids on normal and v-Ki ras transformed NIH-3T3 cells. 1992 Nov-Dec Anticancer Res. pmid:1338278
Dehaut F et al. n-6 polyunsaturated fatty acids increase the neurite length of PC12 cells and embryonic chick motoneurons. 1993 Neurosci. Lett. pmid:8272254
Araya J and Cagalj A [Exclusion of alpha-linolenic acid from diets for rats during several generations. I. Effect on reproduction and postnatal growth]. 1993 Arch Latinoam Nutr pmid:7826185
Tollesson A and Frithz A Transepidermal water loss and water content in the stratum corneum in infantile seborrhoeic dermatitis. 1993 Acta Derm. Venereol. pmid:8095744
Berth-Jones J and Graham-Brown RA Placebo-controlled trial of essential fatty acid supplementation in atopic dermatitis. 1993 Lancet pmid:8099640
Shield MJ et al. Essential fatty acid supplementation in atopic dermatitis. 1993 Lancet pmid:8101623
Dines KC et al. Contrasting effects of treatment with omega-3 and omega-6 essential fatty acids on peripheral nerve function and capillarization in streptozotocin-diabetic rats. 1993 Diabetologia pmid:8270127
Szczesna M [Therapeutic assessment of the evening primrose]. 1993 Rocz Panstw Zakl Hig pmid:8016534
Laivuori H et al. Dietary supplementation with primrose oil or fish oil does not change urinary excretion of prostacyclin and thromboxane metabolites in pre-eclamptic women. 1993 Prostaglandins Leukot. Essent. Fatty Acids pmid:8248275
Stevens EJ et al. Prostacyclin release in experimental diabetes: effects of evening primrose oil. 1993 Prostaglandins Leukot. Essent. Fatty Acids pmid:8248277
Leyton E Disagreeing on how to treat CFS patients. 1993 Can Fam Physician pmid:8347205
Engler MM Comparative study of diets enriched with evening primrose, black currant, borage or fungal oils on blood pressure and pressor responses in spontaneously hypertensive rats. 1993 Prostaglandins Leukot. Essent. Fatty Acids pmid:8259378
Harvey RG A comparison of evening primrose oil and sunflower oil for the management of papulocrustous dermatitis in cats. 1993 Vet. Rec. pmid:8303807
Stevens EJ et al. Essential fatty acid treatment prevents nerve ischaemia and associated conduction anomalies in rats with experimental diabetes mellitus. 1993 Diabetologia pmid:8314443
Joe LA and Hart LL Evening primrose oil in rheumatoid arthritis. 1993 Ann Pharmacother pmid:8305783
Keen H et al. Treatment of diabetic neuropathy with gamma-linolenic acid. The gamma-Linolenic Acid Multicenter Trial Group. 1993 Diabetes Care pmid:8380765
Horrobin DF The effects of gamma-linolenic acid on breast pain and diabetic neuropathy: possible non-eicosanoid mechanisms. 1993 Prostaglandins Leukot. Essent. Fatty Acids pmid:8380930
Hopewell JW et al. The modulation of radiation-induced damage to pig skin by essential fatty acids. 1993 Br. J. Cancer pmid:8391301
Cerin A et al. Hormonal and biochemical profiles of premenstrual syndrome. Treatment with essential fatty acids. 1993 Acta Obstet Gynecol Scand pmid:8392261
Galle AM et al. Biosynthesis of gamma-linolenic acid in developing seeds of borage (Borago officinalis L.). 1993 Biochim. Biophys. Acta pmid:8394742
Kinchington D et al. Lithium gamma-linolenate-induced cytotoxicity against cells chronically infected with HIV-1. 1993 FEBS Lett. pmid:8396048
Tollesson A and Frithz A Borage oil, an effective new treatment for infantile seborrhoeic dermatitis. 1993 Br. J. Dermatol. pmid:8396411
Cameron NE et al. The effects of evening primrose oil on nerve function and capillarization in streptozotocin-diabetic rats: modulation by the cyclo-oxygenase inhibitor flurbiprofen. 1993 Br. J. Pharmacol. pmid:8401950
Phinney SD et al. Abnormal polyunsaturated lipid metabolism in the obese Zucker rat, with partial metabolic correction by gamma-linolenic acid administration. 1993 Metab. Clin. Exp. pmid:8412765
Poisson JP et al. Effect of salt-loading and spontaneous hypertension on in vitro metabolism of [1-14C]linoleic and [2-14C]dihomo-gamma-linolenic acids. 1993 Biochem. Med. Metab. Biol. pmid:8382502
Horrobin DF Fatty acid metabolism in health and disease: the role of delta-6-desaturase. 1993 Am. J. Clin. Nutr. pmid:8386433