gamma-Linolenic acid

Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.

Cross Reference

Introduction

To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid

MeSH term MeSH ID Detail
Stomach Ulcer D013276 75 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Adenocarcinoma D000230 166 associated lipids
Pain D010146 64 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Lung Neoplasms D008175 171 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Inflammation D007249 119 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Body Weight D001835 333 associated lipids
Gastritis D005756 27 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Osteosarcoma D012516 50 associated lipids
Melanoma D008545 69 associated lipids
Kidney Calculi D007669 7 associated lipids
Weight Gain D015430 101 associated lipids
Cardiovascular Diseases D002318 24 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Glioma D005910 112 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Leukemia P388 D007941 43 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Thrombosis D013927 49 associated lipids
Hyperplasia D006965 34 associated lipids
Arteriosclerosis D001161 86 associated lipids
Neuroblastoma D009447 66 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Psoriasis D011565 47 associated lipids
Alcoholism D000437 27 associated lipids
Bacteriuria D001437 7 associated lipids
Respiratory Insufficiency D012131 10 associated lipids
Erectile Dysfunction D007172 19 associated lipids
Liver Cirrhosis, Alcoholic D008104 17 associated lipids
Respiratory Distress Syndrome, Adult D012128 15 associated lipids
Seizures D012640 87 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Hypertension D006973 115 associated lipids
Dermatitis D003872 30 associated lipids
Leukemia, Myeloid, Acute D015470 19 associated lipids
Neoplasms, Hormone-Dependent D009376 23 associated lipids
Dermatitis, Seborrheic D012628 10 associated lipids
Hyperlipidemias D006949 73 associated lipids
Encephalomyelitis, Autoimmune, Experimental D004681 26 associated lipids
Dermatitis, Atopic D003876 19 associated lipids
Premenstrual Syndrome D011293 7 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with gamma-Linolenic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with gamma-Linolenic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with gamma-Linolenic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with gamma-Linolenic acid

Download all related citations
Per page 10 20 50 100 | Total 1121
Authors Title Published Journal PubMed Link
Purasiri P et al. Modulation of cytokine production in vivo by dietary essential fatty acids in patients with colorectal cancer. 1994 Clin. Sci. pmid:7874864
Stillwell W et al. Cholesterol condensation of alpha-linolenic and gamma-linolenic acid-containing phosphatidylcholine monolayers and bilayers. 1994 Biochim. Biophys. Acta pmid:7918592
Fiocchi A et al. The efficacy and safety of gamma-linolenic acid in the treatment of infantile atopic dermatitis. 1994 Jan-Feb J. Int. Med. Res. pmid:7910570
Hauben M Comment: evening primrose oil in the treatment of rheumatoid arthritis--proper application of statistical analysis. 1994 Jul-Aug Ann Pharmacother pmid:7832860
Schoemaker JH Pharmacological treatment of diabetic peripheral neuropathy: challenges and possibilities. 1994 Mar-Apr Br J Clin Pract pmid:8024999
Sasaki S et al. Effects of gamma-linolenic and eicosapentaenoic acids on blood pressure in SHR. 1995 Clin Exp Pharmacol Physiol Suppl pmid:9072404
Luthria DL and Sprecher H Metabolism of deuterium-labeled linoleic, 6,9,12-octadecatrienoic, 8,11,14-eicosatrienoic, and arachidonic acids in the rat. 1995 J. Lipid Res. pmid:8558078
Berth-Jones J et al. Evening primrose oil and atopic eczema. 1995 Lancet pmid:7861894
Morris GM et al. Trophic effects of essential fatty acids on pig skin. 1995 Cell Prolif. pmid:7893841
Rose DP et al. Effects of linoleic acid and gamma-linolenic acid on the growth and metastasis of a human breast cancer cell line in nude mice and on its growth and invasive capacity in vitro. 1995 Nutr Cancer pmid:7491296
Horrobin DF and Morse PF Evening primrose oil and atopic eczema. 1995 Lancet pmid:7823743
Scholey JW and Mills DE Dietary fatty acids and the glomerular hemodynamic response to cyclosporine in borderline hypertensive rats. 1995 Kidney Int. pmid:7723248
Murai A et al. Role of dietary gamma-linolenic acid in liver lipid metabolism in Japanese quail. 1995 Br. Poult. Sci. pmid:8746984
Fan YY et al. Dietary gamma-linolenic acid modulates macrophage-vascular smooth muscle cell interactions. Evidence for a macrophage-derived soluble factor that downregulates DNA synthesis in smooth muscle cells. 1995 Arterioscler. Thromb. Vasc. Biol. pmid:7670954
Sherrington EJ et al. The effect of dietary lipid manipulation on macrophage cell surface molecule expression. 1995 Biochem. Soc. Trans. pmid:7672298
Karasu C et al. Effects of anti-oxidant treatment on sciatic nerve dysfunction in streptozotocin-diabetic rats; comparison with essential fatty acids. 1995 Diabetologia pmid:7713308
Dines KC et al. Comparison of the effects of evening primrose oil and triglycerides containing gamma-linolenic acid on nerve conduction and blood flow in diabetic rats. 1995 J. Pharmacol. Exp. Ther. pmid:7714803
Murray MJ et al. Select dietary fatty acids attenuate cardiopulmonary dysfunction during acute lung injury in pigs. 1995 Am. J. Physiol. pmid:8594921
Bell JG et al. Diets rich in eicosapentaenoic acid and gamma-linolenic acid affect phospholipid fatty acid composition and production of prostaglandins E1, E2 and E3 in turbot (Scophthalmus maximus), a species deficient in delta 5 fatty acid desaturase. 1995 Prostaglandins Leukot. Essent. Fatty Acids pmid:8577782
Rothman D et al. Botanical lipids: effects on inflammation, immune responses, and rheumatoid arthritis. 1995 Semin. Arthritis Rheum. pmid:8578315
Dines CD et al. Nerve function in galactosaemic rats: effects of evening primrose oil and doxazosin. 1995 Eur. J. Pharmacol. pmid:8521914
Koba K et al. Distribution of plasma phosphatidylcholine molecular species in rabbits fed fish oil is modulated by dietary n-6 fatty acids. 1995 Prostaglandins Leukot. Essent. Fatty Acids pmid:8821127
Leichsenring M et al. (n-6)-Fatty acids in plasma lipids of children with atopic bronchial asthma. 1995 Pediatr Allergy Immunol pmid:8822394
Meehan E et al. Influence of an n-6 polyunsaturated fatty acid-enriched diet on the development of tolerance during chronic ethanol administration in rats. 1995 Alcohol. Clin. Exp. Res. pmid:8749808
Goonaratna C Good morning, evening primrose oil. 1995 Ceylon Med J pmid:8689697
de Bravo MG et al. [Effect of dietary supplementation with gamma-linolenic acid on the growth of a human lung carcinoma implanted in nude mice]. 1995 Medicina (B Aires) pmid:8731577
Giamarellos-Bourboulis EJ et al. In-vitro inhibitory activity of gamma-linolenic acid on Escherichia coli strains and its influence on their susceptibilities to various antimicrobial agents. 1995 J. Antimicrob. Chemother. pmid:8522462
Burgess NA et al. Evaluation of four animal models of intrarenal calcium deposition and assessment of the influence of dietary supplementation with essential fatty acids on calcification. 1995 Urol. Res. pmid:8533210
Harbige LS et al. Prevention of experimental autoimmune encephalomyelitis in Lewis rats by a novel fungal source of gamma-linolenic acid. 1995 Br. J. Nutr. pmid:8541276
Sture GH and Lloyd DH Canine atopic disease: therapeutic use of an evening primrose oil and fish oil combination. 1995 Vet. Rec. pmid:8553525
Cartwright-Shamoon JM et al. A complex biochemical modulation of intestinal ion transport in rats fed on high-fat diets. 1995 J. Pediatr. Gastroenterol. Nutr. pmid:7884616
Karikó K et al. Stimulatory effect of unsaturated fatty acids on the level of plasminogen activator inhibitor-1 mRNA in cultured human endothelial cells. 1995 FEBS Lett. pmid:7890029
Rossetti RG et al. Differential regulation of human T lymphocyte protein kinase C activity by unsaturated fatty acids. 1995 Clin. Immunol. Immunopathol. pmid:7554442
Lindskov R and Petersen CS [Oral gamma-linoleic acid (Epogam) in the treatment of atopic dermatitis]. 1995 Ugeskr. Laeg. pmid:7483071
Hrelia S et al. Essential fatty acid metabolism in cultured rat cardiomyocytes in response to either N-6 or N-3 fatty acid supplementation. 1995 Biochem. Biophys. Res. Commun. pmid:7488075
Chajès V et al. Influence of n-3 fatty acids on the growth of human breast cancer cells in vitro: relationship to peroxides and vitamin-E. 1995 Breast Cancer Res. Treat. pmid:7579484
Larsson-Backström C et al. Effects of dietary alpha- and gamma-linolenic acids on liver fatty acids, lipid metabolism, and survival in sepsis. 1995 Shock pmid:7552772
Das UN et al. Local application of gamma-linolenic acid in the treatment of human gliomas. 1995 Cancer Lett. pmid:7634242
Kietzmann M [Pharmacotherapeutic use of antipruritic drugs in skin diseases]. 1995 Tierarztl Prax pmid:7545832
Claassen N et al. Supplemented gamma-linolenic acid and eicosapentaenoic acid influence bone status in young male rats: effects on free urinary collagen crosslinks, total urinary hydroxyproline, and bone calcium content. 1995 Bone pmid:7626328
Manninen P et al. Separation of gamma- and alpha-linolenic acid containing triacylglycerols by capillary supercritical fluid chromatography. 1995 Lipids pmid:7564922
Akahane N et al. Antithrombotic activity of a symmetrical triglyceride with eicosapentaenoic acid and gamma-linolenic acid in guinea pig mesenteric microvasculature. 1995 Thromb. Res. pmid:7660360
Jiang WG et al. Inhibition of hepatocyte growth factor-induced motility and in vitro invasion of human colon cancer cells by gamma-linolenic acid. 1995 Br. J. Cancer pmid:7710939
Jiang WG et al. Regulation of the expression of E-cadherin on human cancer cells by gamma-linolenic acid (GLA). 1995 Cancer Res. pmid:7585549
Huang Z et al. Functional identification of the active-site nucleophile of the human 85-kDa cytosolic phospholipase A2. 1996 Biochemistry pmid:8619991
Fan YY et al. Dietary lipid source alters murine macrophage/vascular smooth muscle cell interactions in vitro. 1996 J. Nutr. pmid:8814195
Omawari N et al. Deficient nitric oxide responsible for reduced nerve blood flow in diabetic rats: effects of L-NAME, L-arginine, sodium nitroprusside and evening primrose oil. 1996 Br. J. Pharmacol. pmid:8733594
Sherrington EJ et al. The effect of dietary lipid manipulation on the uptake of [3H]-triolein by tissues of the rat. 1996 Biochem. Soc. Trans. pmid:8736833
Grant D et al. The antioxidant activity of heparins. 1996 Biochem. Soc. Trans. pmid:8736852
Stainforth JM et al. Clinical aspects of the use of gamma linolenic acid in systemic sclerosis. 1996 Acta Derm. Venereol. pmid:8740271