| MeSH term | MeSH ID | Detail |
|---|---|---|
| Stomach Ulcer | D013276 | 75 associated lipids |
| Kidney Failure, Chronic | D007676 | 51 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Neovascularization, Pathologic | D009389 | 39 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Lupus Erythematosus, Systemic | D008180 | 43 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
gamma-Linolenic acid
Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.
Cross Reference
Introduction
To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid
PubChem Associated disorders and diseases
What pathways are associated with gamma-Linolenic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with gamma-Linolenic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with gamma-Linolenic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
What genes are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
What common seen animal models are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with gamma-Linolenic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Sangeetha P et al. | Free radical generation in human leukocytes by CIS-unsaturated fatty acids is a calmodulin dependent process. | 1990 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:2160083 |
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| Bunce OR and Abou-El-Ela SH | Eicosanoid synthesis and ornithine decarboxylase activity in mammary tumors of rats fed varying levels and types of N-3 and/or N-6 fatty acids. | 1990 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:2177199 |
| Huang YS et al. | The effects of dietary protein and cholesterol on tissue cholesterol contents and N-6 fatty acid compositions in rats and mice fed a gamma-linolenate-rich diet. | 1990 | Monogr Atheroscler | pmid:2178226 |
| Horrobin DF | Evening primrose oil and premenstrual syndrome. | 1990 | Med. J. Aust. | pmid:2233440 |
| Abraham RD et al. | Effects of safflower oil and evening primrose oil in men with a low dihomo-gamma-linolenic level. | 1990 | Atherosclerosis | pmid:2112389 |
| Bégin ME et al. | Differential sensitivity of tumorigenic and genetically related non-tumorigenic cells to cytotoxic polyunsaturated fatty acids. | 1989 Jul-Aug | Anticancer Res. | pmid:2554786 |
| Siliprandi N | [Significance of evening primrose oil in the problem of the nutritional value of poly-unsaturated fatty acids]. | 1989 Jan-Mar | Minerva Dietol Gastroenterol | pmid:2657494 |
| Jenkins AP and Thompson RP | Trophic effect of Efamol on the rat small-intestinal mucosa. | 1989 | Clin. Sci. | pmid:2582727 |
| Pritchard GA et al. | Lipids in breast carcinogenesis. | 1989 | Br J Surg | pmid:2557113 |
| Bates D | Lipids and multiple sclerosis. | 1989 | Biochem. Soc. Trans. | pmid:2546837 |
| Santoli D and Zurier RB | Prostaglandin E precursor fatty acids inhibit human IL-2 production by a prostaglandin E-independent mechanism. | 1989 | J. Immunol. | pmid:2545787 |
| Watkins BA | Levels of dihomo-gamma-linolenate are depressed in heart phosphatidylcholine and phosphatidylethanolamine in the biotin-deficient chick. | 1989 | Poult. Sci. | pmid:2547210 |
| Uccella R et al. | [Action of evening primrose oil on cardiovascular risk factors in insulin-dependent diabetics]. | 1989 | Clin Ter | pmid:2548804 |
| Melnik BC and Plewig G | Is the origin of atopy linked to deficient conversion of omega-6-fatty acids to prostaglandin E1? | 1989 | J. Am. Acad. Dermatol. | pmid:2550526 |
| Tate G et al. | Suppression of acute and chronic inflammation by dietary gamma linolenic acid. | 1989 | J. Rheumatol. | pmid:2550629 |
| Rasmussen JE | Advances in nondietary management of children with atopic dermatitis. | 1989 | Pediatr Dermatol | pmid:2552424 |
| Rasmussen JE | Management of atopic dermatitis. | 1989 | Allergy | pmid:2554743 |
| Vaddadi KS et al. | A double-blind trial of essential fatty acid supplementation in patients with tardive dyskinesia. | 1989 | Psychiatry Res | pmid:2565585 |
| Kragballe K | Dietary supplementation with a combination of n-3 and n-6 fatty acids (super gamma-oil marine) improves psoriasis. | 1989 | Acta Derm. Venereol. | pmid:2566241 |
| Kim MR and Sok DE | Formation of 6,13-dihydroxyoctadecatrienoic acid isomers from gamma-linolenic acid. | 1989 | Biochem. Biophys. Res. Commun. | pmid:2539142 |
| Arnold LE et al. | Gamma-linolenic acid for attention-deficit hyperactivity disorder: placebo-controlled comparison to D-amphetamine. | 1989 | Biol. Psychiatry | pmid:2539203 |
| Ishikawa T et al. | Effects of gammalinolenic acid on plasma lipoproteins and apolipoproteins. | 1989 | Atherosclerosis | pmid:2540757 |
| Botha JH et al. | The role of prostaglandins in the inhibition of cultured carcinoma cell growth produced by gamma-linolenic acid. | 1989 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:2541450 |
| McCollum JR | FDA alert on evening primrose oil. | 1989 | J Am Diet Assoc | pmid:2542387 |
| Morse PF et al. | Meta-analysis of placebo-controlled studies of the efficacy of Epogam in the treatment of atopic eczema. Relationship between plasma essential fatty acid changes and clinical response. | 1989 | Br. J. Dermatol. | pmid:2667620 |
| Jäntti J et al. | Evening primrose oil in rheumatoid arthritis: changes in serum lipids and fatty acids. | 1989 | Ann. Rheum. Dis. | pmid:2649022 |
| Moodley J and Norman RJ | Attempts at dietary alteration of prostaglandin pathways in the management of pre-eclampsia. | 1989 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:2608693 |
| Wilson JH et al. | The effect of very low energy diets on the fatty acid composition of serum lipids. | 1989 | Int J Obes | pmid:2613428 |
| Wright S and Bolton C | Breast milk fatty acids in mothers of children with atopic eczema. | 1989 | Br. J. Nutr. | pmid:2557889 |
| Melnik B and Plewig G | [A new concept of the etiopathogenesis and prevention of atopic dermatitis]. | 1989 | Hautarzt | pmid:2558092 |
| Tomlinson DR et al. | Essential fatty acid treatment--effects on nerve conduction, polyol pathway and axonal transport in streptozotocin diabetic rats. | 1989 | Diabetologia | pmid:2477293 |
| Horrobin DF | Effects of evening primrose oil in rheumatoid arthritis. | 1989 | Ann. Rheum. Dis. | pmid:2688567 |
| Papanikolaou N et al. | Partial protection against acute renal failure by Efamol. | 1989 | Prog. Clin. Biol. Res. | pmid:2798451 |
| Ebden P et al. | A study of evening primrose seed oil in atopic asthma. | 1989 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:2717651 |
| Huang YS et al. | The prostaglandin outflow from perfused mesenteric vasculature of rats fed different fats. | 1989 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:2717652 |
| Jäntti J et al. | Evening primrose oil and olive oil in treatment of rheumatoid arthritis. | 1989 | Clin. Rheumatol. | pmid:2758770 |
| Beaudoin AR et al. | Type of dietary lipids exerts a major influence on the secretory activity of the exocrine pancreas: medium-term studies. | 1989 | Pancreas | pmid:2762271 |
| Stenius-Aarniala B et al. | Evening primose oil and fish oil are ineffective as supplementary treatment of bronchial asthma. | 1989 | Ann Allergy | pmid:2735560 |
| Julu PO | Essential fatty acids prevent slowed nerve conduction in streptozotocin diabetic rats. | 1988 Oct-Dec | J Diabet Complications | pmid:2853165 |
| Choi YS and Sugano M | Effects of dietary alpha- and gamma-linolenic acid on lipid metabolism in young and adult rats. | 1988 | Ann. Nutr. Metab. | pmid:2903713 |
| Abou-el-Ela SH et al. | Eicosanoid synthesis in 7,12-dimethylbenz(a)anthracene-induced mammary carcinomas in Sprague-Dawley rats fed primrose oil, menhaden oil or corn oil diet. | 1988 | Lipids | pmid:3143882 |
| Cronholm T et al. | Influence of dietary fats on pancreatic phospholipids of chronically ethanol-treated rats. | 1988 | Lipids | pmid:2846981 |
| Tate GA et al. | Suppression of monosodium urate crystal-induced acute inflammation by diets enriched with gamma-linolenic acid and eicosapentaenoic acid. | 1988 | Arthritis Rheum. | pmid:2848532 |
| Williams JH | The use of gamma linolenic acid, linoleic acid and natural vitamin E for the treatment of multicentric lymphoma in two dogs. | 1988 | J S Afr Vet Assoc | pmid:2848946 |
| Belch JJ et al. | Effects of altering dietary essential fatty acids on requirements for non-steroidal anti-inflammatory drugs in patients with rheumatoid arthritis: a double blind placebo controlled study. | 1988 | Ann. Rheum. Dis. | pmid:2833184 |
| Chaud M et al. | Gamma-linolenic acid improves the constancy of contractions in uteri from sprayed rats and is metabolized to prostaglandin E1 but not to bisenoic prostanoids. | 1988 | Prostaglandins | pmid:2836889 |
| Wade AE et al. | Effect of 7,12-dimethylbenz(a)anthracene administration on hepatic drug metabolizing enzymes in female rats fed corn, primrose, and menhaden oils. | 1988 | Drug Nutr Interact | pmid:3149238 |
| Biagi PL et al. | A long-term study on the use of evening primrose oil (Efamol) in atopic children. | 1988 | Drugs Exp Clin Res | pmid:3048952 |
| Bordoni A et al. | Evening primrose oil (Efamol) in the treatment of children with atopic eczema. | 1988 | Drugs Exp Clin Res | pmid:3048953 |
| van Doormaal JJ et al. | Effects of short-term high dose intake of evening primrose oil on plasma and cellular fatty acid compositions, alpha-tocopherol levels, and erythropoiesis in normal and type 1 (insulin-dependent) diabetic men. | 1988 | Diabetologia | pmid:3065111 |
| Miller CC and Ziboh VA | Gammalinolenic acid-enriched diet alters cutaneous eicosanoids. | 1988 | Biochem. Biophys. Res. Commun. | pmid:2841938 |
| Novak E | Maintaining remission of Crohn's disease. | 1988 | CMAJ | pmid:3383034 |
| Greaves MW and Corbett MF | Treatment of atopic eczema with evening primrose oil. | 1988 | Br. J. Dermatol. | pmid:3355786 |
| Darlington LG | Do diets rich in polyunsaturated fatty acids affect disease activity in rheumatoid arthritis? | 1988 | Ann. Rheum. Dis. | pmid:3281607 |
| Barcelli UO et al. | A diet containing n-3 and n-6 fatty acids favorably alters the renal phospholipids, eicosanoid synthesis and plasma lipids in nephrotic rats. | 1988 | Lipids | pmid:3237005 |
| Dib A and Carreau JP | Effects of gamma-linolenic acid supplementation on pregnant rats fed a zinc-deficient diet. | 1987 | Ann. Nutr. Metab. | pmid:2821872 |
| Huang YS et al. | Protective effect of gamma-linolenic acid on aspirin-induced gastric hemorrhage in rats. | 1987 | Digestion | pmid:3030865 |
| Horrobin DF | Essential fatty acids, prostaglandins, and alcoholism: an overview. | 1987 | Alcohol. Clin. Exp. Res. | pmid:3032012 |
| Meigel W et al. | [Additional oral therapy of atopic dermatitis with unsaturated fatty acids]. | 1987 | Z. Hautkr. | pmid:2894730 |
| Fujiwara F et al. | Fatty acid modification of cultured neuroblastoma cells by gamma linolenic acid relevant to its antitumor effect. | 1987 | Prostaglandins Leukot Med | pmid:2829239 |
| Van der Merwe CF et al. | Oral gamma-linolenic acid in 21 patients with untreatable malignancy. An ongoing pilot open clinical trial. | 1987 | Br J Clin Pract | pmid:2837264 |
| Simpson LO | Pinch skin grafting or porcine dermis in venous ulcers. | 1987 | Br Med J (Clin Res Ed) | pmid:3109651 |
| Nassar BA et al. | The influence of dietary marine oil (Polepa) and evening primrose oil (Efamol) on prostaglandin production by the rat mesenteric vasculature. | 1987 | Prostaglandins Leukot Med | pmid:3033691 |
| McIllmurray MB and Turkie W | Controlled trial of gamma linolenic acid in Duke's C colorectal cancer. | 1987 | Br Med J (Clin Res Ed) | pmid:3036291 |
| Huang YS and Horrobin DF | Sex differences in n-3 and n-6 fatty acid metabolism in EFA-depleted rats. | 1987 | Proc. Soc. Exp. Biol. Med. | pmid:3037555 |
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| Cunnane SC | Hepatic triacylglycerol accumulation induced by ethanol and carbon tetrachloride: interactions with essential fatty acids and prostaglandins. | 1987 | Alcohol. Clin. Exp. Res. | pmid:3032013 |
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| Papanikolaou N | Alteration of mercuric chloride-induced autoimmune glomerulonephritis in brown-Norway rats by herring oil, evening primrose oil and OKY-046 a selective TXA-synthetase inhibitor. | 1987 | Prostaglandins Leukot Med | pmid:3475724 |
| Papanikolaou N et al. | Effect of thromboxane A2-synthetase inhibitor OKY-046 and evening primrose oil (Efamol) on mercuric chloride induced autoimmune glomerulonephritis in Brown-Norway rats. | 1987 | Prog. Clin. Biol. Res. | pmid:3671393 |
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| Stymne S and Stobart AK | Biosynthesis of gamma-linolenic acid in cotyledons and microsomal preparations of the developing seeds of common borage (Borago officinalis). | 1986 | Biochem. J. | pmid:3028375 |
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| Bégin ME and Das UN | A deficiency in dietary gamma-linolenic and/or eicosapentaenoic acids may determine individual susceptibility to AIDS. | 1986 | Med. Hypotheses | pmid:3014282 |
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| Fujiwara F et al. | Antitumor effect of gamma-linolenic acid on cultured human neuroblastoma cells. | 1986 | Prostaglandins Leukot Med | pmid:3020590 |
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