| MeSH term | MeSH ID | Detail |
|---|---|---|
| Stomach Ulcer | D013276 | 75 associated lipids |
| Kidney Failure, Chronic | D007676 | 51 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Neovascularization, Pathologic | D009389 | 39 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Lupus Erythematosus, Systemic | D008180 | 43 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
gamma-Linolenic acid
Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.
Cross Reference
Introduction
To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid
PubChem Associated disorders and diseases
What pathways are associated with gamma-Linolenic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with gamma-Linolenic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with gamma-Linolenic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
What genes are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
What common seen animal models are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with gamma-Linolenic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Pakala R et al. | Eicosapentaenoic acid and docosahexaenoic acid selectively attenuate U46619-induced smooth muscle cell proliferation. | 1999 | Lipids | pmid:10574655 |
| Stahl A et al. | Identification of the major intestinal fatty acid transport protein. | 1999 | Mol. Cell | pmid:10518211 |
| Ward GR et al. | Effects of gamma-linolenic acid and docosahexaenoic acid in formulae on brain fatty acid composition in artificially reared rats. | 1999 | Lipids | pmid:10580333 |
| Joubert AM et al. | Comparative study of the effects of polyunsaturated fatty acids and their metabolites on cell growth and tyrosine kinase activity in oesophageal carcinoma cells. | 1999 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10582657 |
| Bell HS et al. | Effects of N-6 essential fatty acids on glioma invasion and growth: experimental studies with glioma spheroids in collagen gels. | 1999 | J. Neurosurg. | pmid:10584845 |
| Fan YY et al. | Modulation of atherogenesis by dietary gamma-linolenic acid. | 1999 | Adv. Exp. Med. Biol. | pmid:10667372 |
| Cai J et al. | Inhibition of angiogenic factor- and tumour-induced angiogenesis by gamma linolenic acid. | 1999 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10319914 |
| Ihara-Watanabe M et al. | Effects of dietary alpha- or gamma-linolenic acid on levels and fatty acid compositions of serum and hepatic lipids, and activity and mRNA abundance of 3-hydroxy-3-methylglutaryl CoA reductase in rats. | 1999 | Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. | pmid:10327618 |
| Giamarellos-Bourboulis EJ et al. | In vitro interactions of gamma-linolenic acid and arachidonic acid with ceftazidime on multiresistant Pseudomonas aeruginosa. | 1999 | Lipids | pmid:10419130 |
| Hrelia S et al. | Concentration- and time-dependent effects of gamma-linolenic acid supplementation to tumor cells in culture. | 1999 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10397404 |
| Pakala R et al. | Thromboxane A2 fails to induce proliferation of smooth muscle cells enriched with eicosapentaenoic acid and docosahexaenoic acid. | 1999 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10397410 |
| Woltil HA et al. | Does supplementation of formula with evening primrose and fish oils augment long chain polyunsaturated fatty acid status of low birthweight infants to that of breast-fed counterparts? | 1999 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10359022 |
| DeLuca P et al. | Effects of gammalinolenic acid on interleukin-1 beta and tumor necrosis factor-alpha secretion by stimulated human peripheral blood monocytes: studies in vitro and in vivo. | 1999 | J. Investig. Med. | pmid:10361385 |
| Ilc K et al. | Cytotoxic effects of two gamma linoleic salts (lithium gammalinolenate or meglumine gammalinolenate) alone or associated with a nitrosourea: an experimental study on human glioblastoma cell lines. | 1999 | Anticancer Drugs | pmid:10378677 |
| Tsevegsüren N et al. | Occurrence of gamma-linolenic acid in compositae: a study of Youngia tenuicaulis seed oil. | 1999 | Lipids | pmid:10380126 |
| Wolf LA and Laster SM | Characterization of arachidonic acid-induced apoptosis. | 1999 | Cell Biochem. Biophys. | pmid:10403056 |
| Cai J et al. | Inhibition of the expression of VE-cadherin/catenin complex by gamma linolenic acid in human vascular endothelial cells, and its impact on angiogenesis. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10222244 |
| Leaver HA et al. | Dynamics of reactive oxygen intermediate production in human glioma: n-6 essential fatty acid effects. | 1999 | Eur. J. Clin. Invest. | pmid:10202379 |
| Wu D et al. | Effect of dietary supplementation with black currant seed oil on the immune response of healthy elderly subjects. | 1999 | Am. J. Clin. Nutr. | pmid:10500023 |
| Peterson LD et al. | Dose-dependent effects of dietary gamma-linolenic acid on rat spleen lymphocyte functions. | 1999 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10477037 |
| Haag M et al. | Polyunsaturated fatty acids inhibit Mg2+ -ATPase in basolateral membranes from rat enterocytes. | 1999 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10477038 |
| Huang YS et al. | Cloning of delta12- and delta6-desaturases from Mortierella alpina and recombinant production of gamma-linolenic acid in Saccharomyces cerevisiae. | 1999 | Lipids | pmid:10478922 |
| Gadek JE et al. | Effect of enteral feeding with eicosapentaenoic acid, gamma-linolenic acid, and antioxidants in patients with acute respiratory distress syndrome. Enteral Nutrition in ARDS Study Group. | 1999 | Crit. Care Med. | pmid:10470743 |
| Passorn S et al. | Heterologous expression of Mucor rouxii delta(12)-desaturase gene in Saccharomyces cerevisiae. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10486251 |
| Patel J and Tomlinson DR | Nerve conduction impairment in experimental diabetes-proximodistal gradient of severity. | 1999 | Muscle Nerve | pmid:10487907 |
| Palombo JD et al. | Effect of short-term enteral feeding with eicosapentaenoic and gamma-linolenic acids on alveolar macrophage eicosanoid synthesis and bactericidal function in rats. | 1999 | Crit. Care Med. | pmid:10507617 |
| Senanayake SP and Shahidi F | Enzyme-assisted acidolysis of borage (Borago officinalis L.) and evening primrose (Oenothera biennis L.) oils: incorporation of omega-3 polyunsaturated fatty acids. | 1999 | J. Agric. Food Chem. | pmid:10552616 |
| Gehring W et al. | Effect of topically applied evening primrose oil on epidermal barrier function in atopic dermatitis as a function of vehicle. | 1999 | Arzneimittelforschung | pmid:10442214 |
| Cheung KL | Management of cyclical mastalgia in oriental women: pioneer experience of using gamolenic acid (Efamast) in Asia. | 1999 | Aust N Z J Surg | pmid:10442919 |
| De La Cruz JP et al. | Antioxidant potential of evening primrose oil administration in hyperlipemic rabbits. | 1999 | Life Sci. | pmid:10462081 |
| Schwartz Z et al. | Arachidonic acid directly mediates the rapid effects of 24,25-dihydroxyvitamin D3 via protein kinase C and indirectly through prostaglandin production in resting zone chondrocytes. | 1999 | Endocrinology | pmid:10385391 |
| Henz BM et al. | Double-blind, multicentre analysis of the efficacy of borage oil in patients with atopic eczema. | 1999 | Br. J. Dermatol. | pmid:10233322 |
| Likhodii SS and Cunnane SC | Uptake of 13C-tracer arachidonate and gamma-linolenate by the brain and liver of the suckling rat observed using 13C-NMR. | 1999 | J. Neurochem. | pmid:10349866 |
| Yoshimoto-Furuie K et al. | Effects of oral supplementation with evening primrose oil for six weeks on plasma essential fatty acids and uremic skin symptoms in hemodialysis patients. | 1999 | Nephron | pmid:9933750 |
| Khamaisi M et al. | Metabolic effects of gamma-linolenic acid-alpha-lipoic acid conjugate in streptozotocin diabetic rats. | 1999 | Antioxid. Redox Signal. | pmid:11233149 |
| Murakami K et al. | Evidence for direct binding of fatty acids and eicosanoids to human peroxisome proliferators-activated receptor alpha. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10403814 |
| Burnard SL et al. | Cilazapril and dietary gamma-linolenic acid prevent the deficit in sciatic nerve conduction velocity in the streptozotocin diabetic rat. | 1998 Mar-Apr | J. Diabetes Complicat. | pmid:9559483 |
| Anderson KM et al. | Five-lipoxygenase inhibitors reduce Panc-1 survival: the mode of cell death and synergism of MK886 with gamma linolenic acid. | 1998 Mar-Apr | Anticancer Res. | pmid:9615721 |
| Oakley OR et al. | The effects of lithium gamma-linolenic acid in reversing LPBM5 MuLV induced suppression of hematopoietic progenitor cells in vitro. | 1998 Jan-Jun | Rom J Physiol | pmid:11000861 |
| Frati-Munari AC and Ariza-Andraca CR | [Treatment of diabetic neuropathy]. | 1998 Jan-Feb | Gac Med Mex | pmid:9658700 |
| Martens-Lobenhoffer J and Meyer FP | Pharmacokinetic data of gamma-linolenic acid in healthy volunteers after the administration of evening primrose oil (Epogam). | 1998 | Int J Clin Pharmacol Ther | pmid:9707349 |
| Johnson SR | Premenstrual syndrome therapy. | 1998 | Clin Obstet Gynecol | pmid:9646973 |
| Engler MM et al. | Effects of dietary gamma-linolenic acid on blood pressure and adrenal angiotensin receptors in hypertensive rats. | 1998 | Proc. Soc. Exp. Biol. Med. | pmid:9648942 |
| Giamarellos-Bourboulis EJ et al. | In vitro activity of polyunsaturated fatty acids on Pseudomonas aeruginosa: relationship to lipid peroxidation. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9654401 |
| Kahler CP and Du Plooy WJ | Effect of gammalinolenic acid, dihomogammalinolenic acid, ascorbyl-6-gammalinolenic acid, and ascorbyl-6-dihomo gammalinolenic acid on histamine- and methacholine-induced contraction of the isolated guinea pig tracheal chain. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9654407 |
| Solomon LZ et al. | Bladder cancer recurrence by implantation of exfoliated cells: is gamma-linolenic acid an effective tumoricidal agent? | 1998 | Br J Urol | pmid:9698674 |
| Ramesh G and Das UN | Effect of evening primrose and fish oils on two stage skin carcinogenesis in mice. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9844986 |
| Kuruvilla R et al. | Evening primrose oil treatment corrects reduced conduction velocity but not depletion of arachidonic acid in nerve from streptozotocin-induced diabetic rats. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9844993 |
| Schellhammer PF | Intravesical chemotherapy with gamma linolenic acid becomes a reality. | 1998 | J. Urol. | pmid:9817299 |
| Solomon LZ et al. | Intravesical chemotherapy with gamma linolenic acid becomes a realistic prospect in serum-free applications: in vitro cytotoxicity and systemic absorption studies. | 1998 | J. Urol. | pmid:9817384 |