gamma-Linolenic acid

Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.

Cross Reference

Introduction

To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid

MeSH term MeSH ID Detail
Stomach Ulcer D013276 75 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Adenocarcinoma D000230 166 associated lipids
Pain D010146 64 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Lung Neoplasms D008175 171 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Inflammation D007249 119 associated lipids
Per page 10 20 50 100 | Total 85

PubChem Associated disorders and diseases

What pathways are associated with gamma-Linolenic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with gamma-Linolenic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with gamma-Linolenic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with gamma-Linolenic acid

Download all related citations
Per page 10 20 50 100 | Total 1121
Authors Title Published Journal PubMed Link
Fuller MA et al. Activity of soybean lipoxygenase isoforms against esterified fatty acids indicates functional specificity. 2001 Arch. Biochem. Biophys. pmid:11361131
Chakrabarti KB et al. Modification of doxorubicin-induced cardiotoxicity: effect of essential fatty acids and ICRF-187 (dexrazoxane). 2001 Eur. J. Cancer pmid:11435077
Banni S et al. Vaccenic acid feeding increases tissue levels of conjugated linoleic acid and suppresses development of premalignant lesions in rat mammary gland. 2001 Nutr Cancer pmid:12094634
Olguín EJ et al. The effect of low light flux and nitrogen deficiency on the chemical composition of Spirulina sp. (Arthrospira) grown on digested pig waste. 2001 Bioresour. Technol. pmid:11211071
Hounsom L et al. Oxidative stress participates in the breakdown of neuronal phenotype in experimental diabetic neuropathy. 2001 Diabetologia pmid:11357471
Ito Y et al. Effects of polyunsaturated fatty acids on atrophic gastritis in a Japanese population. 2001 Cancer Lett. pmid:11165751
Reinikainen M et al. The toxicities of a polyunsaturated fatty acid and a microcystin to Daphnia magna. 2001 Environ. Toxicol. pmid:11594032
Agatha G et al. Fatty acid composition of lymphocyte membrane phospholipids in children with acute leukemia. 2001 Cancer Lett. pmid:11597788
Wollheim FA [Meager support for herbal therapy of rheumatoid arthritis]. 2001 Lakartidningen pmid:11699249
Kast RE Borage oil reduction of rheumatoid arthritis activity may be mediated by increased cAMP that suppresses tumor necrosis factor-alpha. 2001 Int. Immunopharmacol. pmid:11710548
Ide T et al. Dietary mold oil rich in gamma linolenic acid increases insulin-dependent glucose utilization in isolated rat adipocytes. 2001 Comp. Biochem. Physiol. B, Biochem. Mol. Biol. pmid:11567903
Kaku S et al. Dietary gamma-linolenic acid dose-dependently modifies fatty acid composition and immune parameters in rats. 2001 Prostaglandins Leukot. Essent. Fatty Acids pmid:11728173
Colquhoun A and Schumacher RI gamma-Linolenic acid and eicosapentaenoic acid induce modifications in mitochondrial metabolism, reactive oxygen species generation, lipid peroxidation and apoptosis in Walker 256 rat carcinosarcoma cells. 2001 Biochim. Biophys. Acta pmid:11731331
Birch AE et al. Antioxidant properties of evening primrose seed extracts. 2001 J. Agric. Food Chem. pmid:11559161
Demmelmair H et al. Influence of formulas with borage oil or borage oil plus fish oil on the arachidonic acid status in premature infants. 2001 Lipids pmid:11485158
Guil-Guerrero JL et al. Occurrence and characterization of oils rich in gamma-linolenic acid (III): the taxonomical value of the fatty acids in Echium (Boraginaceae). 2001 Phytochemistry pmid:11524120
Ford I et al. The effects of treatment with alpha-lipoic acid or evening primrose oil on vascular hemostatic and lipid risk factors, blood flow, and peripheral nerve conduction in the streptozotocin-diabetic rat. 2001 Metab. Clin. Exp. pmid:11474472
Tsimaratos M et al. Gamma-linolenic acid restores renal medullary thick ascending limb Na(+),K(+)-ATPase activity in diabetic rats. 2001 J. Nutr. pmid:11739860
Mainou-Fowler T et al. Gamma-linolenic acid induces apoptosis in B-chronic lymphocytic leukaemia cells in vitro. 2001 Leuk. Lymphoma pmid:11426562
Serrano I et al. Ethanol-induced dimorphism and lipid composition changes in Mucor fragilis CCMI 142. 2001 Lett. Appl. Microbiol. pmid:11442823
Hou X et al. 2,3-Dinor-5,6-dihydro-15-F(2t)-isoprostane: a bioactive prostanoid metabolite. 2001 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:11448840
Fan YY et al. Dietary gamma-linolenic acid suppresses aortic smooth muscle cell proliferation and modifies atherosclerotic lesions in apolipoprotein E knockout mice. 2001 J. Nutr. pmid:11385052
Nwankwo JO Repression of cellular anaplerosis as the hypothesized mechanism of gamma-linolenic acid-induced toxicity to tumor cells. 2001 Med. Hypotheses pmid:11388772
Furse RK et al. Gammalinolenic acid, an unsaturated fatty acid with anti-inflammatory properties, blocks amplification of IL-1 beta production by human monocytes. 2001 J. Immunol. pmid:11418687
Thies F et al. Dietary supplementation with gamma-linolenic acid or fish oil decreases T lymphocyte proliferation in healthy older humans. 2001 J. Nutr. pmid:11435508
Yogo Y and Fujishima S [Nutritional support for ARDS]. 2001 Nippon Rinsho pmid:11439576
Frenoux JM et al. A polyunsaturated fatty acid diet lowers blood pressure and improves antioxidant status in spontaneously hypertensive rats. 2001 J. Nutr. pmid:11208936
Berry JA Benign breast pain. New approaches manage this common condition more effectively. 2001 Adv Nurse Pract pmid:12400335
Cunnane SC et al. NMR and isotope ratio mass spectrometry studies of in vivo uptake and metabolism of polyunsaturates by the developing rat brain. 2001 Apr-Jun J. Mol. Neurosci. pmid:11478372
Nwankwo JO and Robbins ME Peroxisome proliferator-activated receptor- gamma expression in human malignant and normal brain, breast and prostate-derived cells. 2001 Apr-May Prostaglandins Leukot. Essent. Fatty Acids pmid:11418018
Borenshtein D et al. Cataract development in diabetic sand rats treated with alpha-lipoic acid and its gamma-linolenic acid conjugate. 2001 Jan-Feb Diabetes Metab. Res. Rev. pmid:11241890
Zavodnik LB et al. [Effect of gamma-linolenic acid on microsomal oxidation in the rat liver following gamma-irradiation]. 2001 Jul-Aug Eksp Klin Farmakol pmid:11589114
OtleÅŸ S and Pire R Fatty acid composition of Chlorella and Spirulina microalgae species. 2001 Nov-Dec J AOAC Int pmid:11767135
Keegan A et al. Corpus cavernosum dysfunction in diabetic rats: effects of combined alpha-lipoic acid and gamma-linolenic acid treatment. 2001 Sep-Oct Diabetes Metab. Res. Rev. pmid:11747143
Simoncíkova P et al. Comparison of the extrapancreatic action of gamma-linolenic acid and n-3 PUFAs in the high fat diet-induced insulin resistance [corrected]. 2002 Endocr Regul pmid:12466014
Leaver HA et al. Highly unsaturated fatty acid induced tumour regression in glioma pharmacodynamics and bioavailability of gamma linolenic acid in an implantation glioma model: effects on tumour biomass, apoptosis and neuronal tissue histology. 2002 Prostaglandins Leukot. Essent. Fatty Acids pmid:12445487
Blommers J et al. Evening primrose oil and fish oil for severe chronic mastalgia: a randomized, double-blind, controlled trial. 2002 Am. J. Obstet. Gynecol. pmid:12439536
Senanayake SP and Shahidi F Structured lipids via lipase-catalyzed incorporation of eicosapentaenoic acid into borage (Borago officinalis L.) and evening primrose (Oenothera biennis L.) oils. 2002 J. Agric. Food Chem. pmid:11804516
Leigh-Firbank EC et al. Eicosapentaenoic acid and docosahexaenoic acid from fish oils: differential associations with lipid responses. 2002 Br. J. Nutr. pmid:12010583
Braddock R et al. gamma-Linoleic acid and ascorbic acid ameliorate the effects of experimental diabetes on electrolyte and bone homeostasis in pregnant rats. 2002 J. Endocrinol. pmid:12010635
Crook TJ et al. The effects of meglumine gamma linolenic acid (MeGLA) on an organ culture model of superficial bladder cancer. 2002 Urol. Res. pmid:11942327
García-Maroto F et al. Cloning and molecular characterization of the delta6-desaturase from two echium plant species: production of GLA by heterologous expression in yeast and tobacco. 2002 Lipids pmid:12030323
Colquhoun A Gamma-linolenic acid alters the composition of mitochondrial membrane subfractions, decreases outer mitochondrial membrane binding of hexokinase and alters carnitine palmitoyltransferase I properties in the Walker 256 rat tumour. 2002 Biochim. Biophys. Acta pmid:12069851
Menéndez JA et al. Synergistic interaction between vinorelbine and gamma-linolenic acid in breast cancer cells. 2002 Breast Cancer Res. Treat. pmid:12058962
Cook D et al. Modification of fatty acid composition in tomato (Lycopersicon esculentum) by expression of a borage delta6-desaturase. 2002 Mol. Biotechnol. pmid:12059112
Leaver HA et al. Antitumour and pro-apoptotic actions of highly unsaturated fatty acids in glioma. 2002 Prostaglandins Leukot. Essent. Fatty Acids pmid:12051954
Chung S et al. Gamma-linolenic acid in borage oil reverses epidermal hyperproliferation in guinea pigs. 2002 J. Nutr. pmid:12368400
Gillis RC et al. Eicosapentaenoic acid and gamma-linolenic acid induce apoptosis in HL-60 cells. 2002 J. Surg. Res. pmid:12384078
Das UN Abrupt and complete occlusion of tumor-feeding vessels by gamma-linolenic acid. 2002 Nutrition pmid:12297217
Samuels R et al. Hypocholesterolemic effect of spirulina in patients with hyperlipidemic nephrotic syndrome. 2002 J Med Food pmid:12487756