gamma-Linolenic acid

Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.

Cross Reference

Introduction

To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid

MeSH term MeSH ID Detail
Stomach Ulcer D013276 75 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Adenocarcinoma D000230 166 associated lipids
Pain D010146 64 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Lung Neoplasms D008175 171 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Inflammation D007249 119 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with gamma-Linolenic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with gamma-Linolenic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with gamma-Linolenic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with gamma-Linolenic acid

Download all related citations
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Authors Title Published Journal PubMed Link
Miyake JA et al. Gamma-linolenic acid inhibits both tumour cell cycle progression and angiogenesis in the orthotopic C6 glioma model through changes in VEGF, Flt1, ERK1/2, MMP2, cyclin D1, pRb, p53 and p27 protein expression. 2009 Lipids Health Dis pmid:19292920
Ge H et al. Gamma-linolenic acid induces apoptosis and lipid peroxidation in human chronic myelogenous leukemia K562 cells. 2009 Cell Biol. Int. pmid:19356705
Weaver KL et al. Effect of dietary fatty acids on inflammatory gene expression in healthy humans. 2009 J. Biol. Chem. pmid:19359242
Zaniewska A et al. The activity of lysosomal exoglycosidases in serum of alcohol-dependent men supplemented with borage oil enriched with vitamin E. 2009 J Med Food pmid:19735195
Labruzzo BA et al. Which complementary therapies can help patients with PMS? 2009 J Fam Pract pmid:19874736
Senapati S et al. Evening primrose oil is effective in atopic dermatitis: a randomized placebo-controlled trial. 2008 Sep-Oct Indian J Dermatol Venereol Leprol pmid:19052401
Pontes-Arruda A et al. The use of an inflammation-modulating diet in patients with acute lung injury or acute respiratory distress syndrome: a meta-analysis of outcome data. 2008 Nov-Dec JPEN J Parenter Enteral Nutr pmid:18974237
Preiser JC Nutrition therapy for acute respiratory distress syndrome. 2008 Nov-Dec JPEN J Parenter Enteral Nutr pmid:18974251
Dickerson RN Modified EN support for patients with acute respiratory distress syndrome. 2008 Nov-Dec JPEN J Parenter Enteral Nutr pmid:18974252
Funtikova NS and Mysiakina IS [Effects of conditions for obtaining sporangiospores of the inoculum on the morphology and productivity of the fungus Mucor circinelloides var. lusitanicus 12 M, a producer of gamma-linolenic acid]. 2008 Jul-Aug Prikl. Biokhim. Mikrobiol. pmid:18924414
Mysiakina IS and Funtikova NS [Activity of NAD-dependent isocitrate dehydrogenase, isocitrate lyase, and malate dehydrogenase in Mucor circinelloides var. lusitanicus INMI under different modes of nitrogen supply]. 2008 Jul-Aug Mikrobiologiia pmid:18825970
Mysiakina IS and Funtikova NS [Metabolic characteristics and lipid composition of yeastlike cells and mycelium of Mucor circinelloides var. lusitanicus INMI grown at a high glucose content in the medium]. 2008 Jul-Aug Mikrobiologiia pmid:18825971
Yen CH et al. Linoleic acid metabolite levels and transepidermal water loss in children with atopic dermatitis. 2008 Ann. Allergy Asthma Immunol. pmid:18254485
Clément M et al. Purification and identification of bovine cheese whey fatty acids exhibiting in vitro antifungal activity. 2008 J. Dairy Sci. pmid:18565910
Leskinen H et al. Regioisomeric structure determination of alpha- and gamma-linolenoyldilinoleoylglycerol in blackcurrant seed oil by silver ion high-performance liquid chromatography and mass spectrometry. 2008 Anal. Chem. pmid:18578547
Guo JP and Xue H [Prepared evening primrose oil microspheres by spray drying]. 2008 Zhongguo Zhong Yao Za Zhi pmid:18589773
Fakas S et al. Gamma-linolenic acid production by Cunninghamella echinulata growing on complex organic nitrogen sources. 2008 Bioresour. Technol. pmid:18609766
Yu Q et al. LC/ESR/MS study of spin trapped carbon-centred radicals formed from in vitro lipoxygenase-catalysed peroxidation of gamma-linolenic acid. 2008 Free Radic. Res. pmid:18484409
Thumfart J et al. Magnesium stimulates renal phosphate reabsorption. 2008 Am. J. Physiol. Renal Physiol. pmid:18701629
Bloom P Atopic dermatitis: the quest for the silver bullet. 2008 Vet. J. pmid:18554562
Adam O [Ankylosing Spondylitis and convenient nutrition]. 2008 Wien Med Wochenschr pmid:18560957
Wedig KE and Whitsett JA Down the primrose path: petechiae in a neonate exposed to herbal remedy for parturition. 2008 J. Pediatr. pmid:18154917
Nasrollahzadeh J et al. The influence of feeding linoleic, gamma-linolenic and docosahexaenoic acid rich oils on rat brain tumor fatty acids composition and fatty acid binding protein 7 mRNA expression. 2008 Lipids Health Dis pmid:19014610
Shi LM et al. [Effects of gamma linolenic acid on atherosclerosis induced by cholesterol-rich diet in rats]. 2008 Zhongguo Zhong Yao Za Zhi pmid:19260318
Nandakumar M and Tan MW Gamma-linolenic and stearidonic acids are required for basal immunity in Caenorhabditis elegans through their effects on p38 MAP kinase activity. 2008 PLoS Genet. pmid:19023415
Won J et al. Stability analysis of zinc oxide-nanoencapsulated conjugated linoleic acid and gamma-linolenic acid. 2008 J. Food Sci. pmid:19019122
Geppert J et al. Co-supplementation of healthy women with fish oil and evening primrose oil increases plasma docosahexaenoic acid, gamma-linolenic acid and dihomo-gamma-linolenic acid levels without reducing arachidonic acid concentrations. 2008 Br. J. Nutr. pmid:17678567
Rühl R et al. Fatty acid composition of serum lipid classes in mice following allergic sensitisation with or without dietary docosahexaenoic acid-enriched fish oil substitution. 2008 Br. J. Nutr. pmid:18005485
Chilton FH et al. Mechanisms by which botanical lipids affect inflammatory disorders. 2008 Am. J. Clin. Nutr. pmid:18258646
Surette ME et al. The impact of a medical food containing gammalinolenic and eicosapentaenoic acids on asthma management and the quality of life of adult asthma patients. 2008 Curr Med Res Opin pmid:18194593
Cui PH et al. Monoepoxy octadecadienoates and monoepoxy octadecatrienoates 1: NMR spectral characterization. 2008 Chem. Phys. Lipids pmid:18339314
Wu CC et al. Metabolism of omega-6 polyunsaturated fatty acids in women with dysmenorrhea. 2008 Asia Pac J Clin Nutr pmid:18296341
Jeennor S et al. Evaluation of inoculum performance for enhancing gamma-linolenic acid production from Mucor rouxii. 2008 Lett. Appl. Microbiol. pmid:18298455
Puch F et al. Consumption of functional fermented milk containing borage oil, green tea and vitamin E enhances skin barrier function. 2008 Exp. Dermatol. pmid:18318715
Vinggaard AM et al. Screening of 397 chemicals and development of a quantitative structure--activity relationship model for androgen receptor antagonism. 2008 Chem. Res. Toxicol. pmid:18324785
Song C et al. Long-chain polyunsaturated fatty acids modulate interleukin-1beta-induced changes in behavior, monoaminergic neurotransmitters, and brain inflammation in rats. 2008 J. Nutr. pmid:18424607
Choi GG et al. Enhanced biomass and gamma-linolenic acid production of mutant strain Arthrospira platensis. 2008 J. Microbiol. Biotechnol. pmid:18388474
Prociuk MA et al. Cholesterol-induced stimulation of platelet aggregation is prevented by a hempseed-enriched diet. 2008 Can. J. Physiol. Pharmacol. pmid:18418423
Kanehara S et al. Undershirts coated with borage oil alleviate the symptoms of atopic dermatitis in children. 2007 Sep-Oct Eur J Dermatol pmid:17673396
Puri BK Long-chain polyunsaturated fatty acids and the pathophysiology of myalgic encephalomyelitis (chronic fatigue syndrome). 2007 J. Clin. Pathol. pmid:16935966
Martin TA et al. Enhanced tight junction function in human breast cancer cells by antioxidant, selenium and polyunsaturated lipid. 2007 J. Cell. Biochem. pmid:17243118
Matta JA et al. TRPV1 is a novel target for omega-3 polyunsaturated fatty acids. 2007 J. Physiol. (Lond.) pmid:17038422
Pitel S et al. At low doses, a gamma-linolenic acid-lipoic acid conjugate is more effective than docosahexaenoic acid-enriched phospholipids in preventing neuropathy in diabetic rats. 2007 J. Nutr. pmid:17237313
Christie A et al. Effectiveness of nonpharmacological and nonsurgical interventions for patients with rheumatoid arthritis: an overview of systematic reviews. 2007 Phys Ther pmid:17906290
Dobryniewski J et al. [The gamma-linolenic acid (GLA)--the therapeutic value]. 2007 Prz. Lek. pmid:17892041
Theilla M et al. A diet enriched in eicosapentanoic acid, gamma-linolenic acid and antioxidants in the prevention of new pressure ulcer formation in critically ill patients with acute lung injury: A randomized, prospective, controlled study. 2007 Clin Nutr pmid:17933438
Garaiova I et al. A randomised cross-over trial in healthy adults indicating improved absorption of omega-3 fatty acids by pre-emulsification. 2007 Nutr J pmid:17254329
Das UN Gamma-linolenic acid therapy of human glioma-a review of in vitro, in vivo, and clinical studies. 2007 Med. Sci. Monit. pmid:17599036
Schirmer MA and Phinney SD Gamma-linolenate reduces weight regain in formerly obese humans. 2007 J. Nutr. pmid:17513402
Pinna A et al. Effect of oral linoleic and gamma-linolenic acid on meibomian gland dysfunction. 2007 Cornea pmid:17413949