gamma-Linolenic acid

Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.

Cross Reference

Introduction

To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid

MeSH term MeSH ID Detail
Stomach Ulcer D013276 75 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Adenocarcinoma D000230 166 associated lipids
Pain D010146 64 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Lung Neoplasms D008175 171 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Inflammation D007249 119 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with gamma-Linolenic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with gamma-Linolenic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with gamma-Linolenic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with gamma-Linolenic acid

Download all related citations
Per page 10 20 50 100 | Total 1121
Authors Title Published Journal PubMed Link
Santoli D and Zurier RB Prostaglandin E precursor fatty acids inhibit human IL-2 production by a prostaglandin E-independent mechanism. 1989 J. Immunol. pmid:2545787
Kragballe K Dietary supplementation with a combination of n-3 and n-6 fatty acids (super gamma-oil marine) improves psoriasis. 1989 Acta Derm. Venereol. pmid:2566241
Kim MR and Sok DE Formation of 6,13-dihydroxyoctadecatrienoic acid isomers from gamma-linolenic acid. 1989 Biochem. Biophys. Res. Commun. pmid:2539142
Arnold LE et al. Gamma-linolenic acid for attention-deficit hyperactivity disorder: placebo-controlled comparison to D-amphetamine. 1989 Biol. Psychiatry pmid:2539203
Ishikawa T et al. Effects of gammalinolenic acid on plasma lipoproteins and apolipoproteins. 1989 Atherosclerosis pmid:2540757
Botha JH et al. The role of prostaglandins in the inhibition of cultured carcinoma cell growth produced by gamma-linolenic acid. 1989 Prostaglandins Leukot. Essent. Fatty Acids pmid:2541450
McCollum JR FDA alert on evening primrose oil. 1989 J Am Diet Assoc pmid:2542387
Morse PF et al. Meta-analysis of placebo-controlled studies of the efficacy of Epogam in the treatment of atopic eczema. Relationship between plasma essential fatty acid changes and clinical response. 1989 Br. J. Dermatol. pmid:2667620
Jäntti J et al. Evening primrose oil in rheumatoid arthritis: changes in serum lipids and fatty acids. 1989 Ann. Rheum. Dis. pmid:2649022
Moodley J and Norman RJ Attempts at dietary alteration of prostaglandin pathways in the management of pre-eclampsia. 1989 Prostaglandins Leukot. Essent. Fatty Acids pmid:2608693
Wilson JH et al. The effect of very low energy diets on the fatty acid composition of serum lipids. 1989 Int J Obes pmid:2613428
Wright S and Bolton C Breast milk fatty acids in mothers of children with atopic eczema. 1989 Br. J. Nutr. pmid:2557889
Stenius-Aarniala B et al. Evening primose oil and fish oil are ineffective as supplementary treatment of bronchial asthma. 1989 Ann Allergy pmid:2735560
Siliprandi N [Significance of evening primrose oil in the problem of the nutritional value of poly-unsaturated fatty acids]. 1989 Jan-Mar Minerva Dietol Gastroenterol pmid:2657494
Bégin ME et al. Differential sensitivity of tumorigenic and genetically related non-tumorigenic cells to cytotoxic polyunsaturated fatty acids. 1989 Jul-Aug Anticancer Res. pmid:2554786
Schrek R An animal model for intractable chronic lymphocytic leukemia. 1990 Med. Hypotheses pmid:1963468
Hayashi Y et al. Anticancer activity of free gamma-linolenic acid on AH-109A rat hepatoma cells and the effect of serum albumin on anticancer activity of gamma-linolenic acid in vitro. 1990 J. Pharmacobio-dyn. pmid:1965510
Sharpe GR and Farr PM Evening primrose oil and eczema. 1990 Lancet pmid:1969047
Horrobin DF and Stewart C Evening primrose oil in atopic eczema. 1990 Lancet pmid:1969596
Sharpe GR and Farr PM Evening primrose oil and eczema. 1990 Lancet pmid:1971352
Horrobin DF and Stewart C Evening primrose oil and atopic eczema. 1990 Lancet pmid:1973228
Chapkin RS and Carmichael SL Effect of dietary blackcurrant seed oil on mouse macrophage subclasses of choline and ethanolamine glycerophospholipids. 1990 J. Nutr. pmid:1974284
Dodge JA et al. Paradoxical effects of essential fatty acid supplementation on lipid profiles and sweat electrolytes in cystic fibrosis. 1990 Br. J. Nutr. pmid:2185826
Mansel RE et al. A randomized trial of dietary intervention with essential fatty acids in patients with categorized cysts. 1990 Ann. N. Y. Acad. Sci. pmid:2192634
Nakahara T et al. Inhibitory effects of mold oil including gamma-linolenate on platelet thrombus formation in mesenteric microvessels of the rat. 1990 Thromb. Res. pmid:2156348
Roemen TH et al. Quantitative assessment of gamma-linolenic acid in human blood and plasma with capillary gas chromatography. 1990 J. Chromatogr. pmid:2166745
Cleland LG et al. The effect of dietary fish oil supplement upon the content of dihomo-gammalinolenic acid in human plasma phospholipids. 1990 Prostaglandins Leukot. Essent. Fatty Acids pmid:2169063
van der Merwe CF et al. The effect of gamma-linolenic acid, an in vitro cytostatic substance contained in evening primrose oil, on primary liver cancer. A double-blind placebo controlled trial. 1990 Prostaglandins Leukot. Essent. Fatty Acids pmid:2169638
Hirschberg Y et al. The response to endotoxin in guinea pigs after intravenous black currant seed oil. 1990 Lipids pmid:2170795
Simpson LO Melanoma and fatty acids. 1990 N. Z. Med. J. pmid:2173823
Gamolenic acid in atopic eczema: Epogam. 1990 Drug Ther Bull pmid:2131219
Gateley CA and Mansel RE Management of cyclical breast pain. 1990 Br J Hosp Med pmid:2364227
Watson J et al. Mechanism of action of polyunsaturated fatty acids in rheumatoid arthritis. 1990 Biochem. Soc. Trans. pmid:2379720
Singer P et al. N-6 and N-3 PUFA in liver lipids, thromboxane formation and blood pressure from SHR during diets supplemented with evening primrose, sunflowerseed or fish oil. 1990 Prostaglandins Leukot. Essent. Fatty Acids pmid:2336450
Huang YS et al. Stress modulates cholesterol-induced changes in plasma and liver fatty acid composition in rats fed n-6 fatty acid-rich oils. 1990 Proc. Soc. Exp. Biol. Med. pmid:2399256
Singer P et al. Blood pressure and serum lipids from SHR after diets supplemented with evening primrose, sunflowerseed or fish oil. 1990 Prostaglandins Leukot. Essent. Fatty Acids pmid:2399267
Khoo SK et al. Evening primrose oil and treatment of premenstrual syndrome. 1990 Med. J. Aust. pmid:2201888
Gateley CA et al. Mastalgia refractory to drug treatment. 1990 Br J Surg pmid:2224458
Bordoni A [Significance and motivation of the clinical use of essential fatty acid derivatives, especially gamma-linolenic acid]. 1990 Clin Ter pmid:2158408
Jamal GA and Carmichael H The effect of gamma-linolenic acid on human diabetic peripheral neuropathy: a double-blind placebo-controlled trial. 1990 Diabet. Med. pmid:2159860
Sangeetha P et al. Free radical generation in human leukocytes by CIS-unsaturated fatty acids is a calmodulin dependent process. 1990 Prostaglandins Leukot. Essent. Fatty Acids pmid:2160083
Melnik BC [A chance for the prevention of atopic diseases]. 1990 Monatsschr Kinderheilkd pmid:2162007
Bunce OR and Abou-El-Ela SH Eicosanoid synthesis and ornithine decarboxylase activity in mammary tumors of rats fed varying levels and types of N-3 and/or N-6 fatty acids. 1990 Prostaglandins Leukot. Essent. Fatty Acids pmid:2177199
Huang YS et al. The effects of dietary protein and cholesterol on tissue cholesterol contents and N-6 fatty acid compositions in rats and mice fed a gamma-linolenate-rich diet. 1990 Monogr Atheroscler pmid:2178226
Horrobin DF Evening primrose oil and premenstrual syndrome. 1990 Med. J. Aust. pmid:2233440
Kawashima Y et al. Peroxisome proliferators enhance linoleic acid metabolism in rat liver. Increased biosynthesis of omega 6 polyunsaturated fatty acids. 1990 J. Biol. Chem. pmid:2160962
Abraham RD et al. Effects of safflower oil and evening primrose oil in men with a low dihomo-gamma-linolenic level. 1990 Atherosclerosis pmid:2112389
Ikushima S et al. Gamma linolenic acid alters the cytotoxic activity of anticancer drugs on cultured human neuroblastoma cells. 1990 Jul-Aug Anticancer Res. pmid:2166461
Sircar S et al. Transformation renders MDR cells more sensitive to polyunsaturated fatty acids. 1990 Nov-Dec Anticancer Res. pmid:2178327
Chapkin RS and Coble KJ Utilization of gammalinolenic acid by mouse peritoneal macrophages. 1991 Biochim. Biophys. Acta pmid:1655039