gamma-Linolenic acid

Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.

Cross Reference

Introduction

To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid

MeSH term MeSH ID Detail
Stomach Ulcer D013276 75 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Adenocarcinoma D000230 166 associated lipids
Pain D010146 64 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Lung Neoplasms D008175 171 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Inflammation D007249 119 associated lipids
Per page 10 20 50 100 | Total 85

PubChem Associated disorders and diseases

What pathways are associated with gamma-Linolenic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with gamma-Linolenic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with gamma-Linolenic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with gamma-Linolenic acid

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Authors Title Published Journal PubMed Link
Yoon S et al. The therapeutic effect of evening primrose oil in atopic dermatitis patients with dry scaly skin lesions is associated with the normalization of serum gamma-interferon levels. 2002 Jan-Feb Skin Pharmacol. Appl. Skin Physiol. pmid:11803254
Simoncíkova P et al. Comparison of the extrapancreatic action of gamma-linolenic acid and n-3 PUFAs in the high fat diet-induced insulin resistance [corrected]. 2002 Endocr Regul pmid:12466014
Leaver HA et al. Highly unsaturated fatty acid induced tumour regression in glioma pharmacodynamics and bioavailability of gamma linolenic acid in an implantation glioma model: effects on tumour biomass, apoptosis and neuronal tissue histology. 2002 Prostaglandins Leukot. Essent. Fatty Acids pmid:12445487
Blommers J et al. Evening primrose oil and fish oil for severe chronic mastalgia: a randomized, double-blind, controlled trial. 2002 Am. J. Obstet. Gynecol. pmid:12439536
Senanayake SP and Shahidi F Positional distribution of FA in TAG of enzymatically modified borage and evening primrose oils. 2002 Lipids pmid:12371752
Turon F et al. A direct method for regiospecific analysis of TAG using alpha-MAG. 2002 Lipids pmid:12371754
Dyer O Doctor accused of giving false information to drug trial. 2002 BMJ pmid:12269314
Tso P et al. Intestinal absorption and lymphatic transport of a high gamma-linolenic acid canola oil in lymph fistula Sprague-Dawley rats. 2002 J. Nutr. pmid:11823581
Deng X et al. Regulation of the rat SREBP-1c promoter in primary rat hepatocytes. 2002 Biochem. Biophys. Res. Commun. pmid:11779162
Senanayake SP and Shahidi F Structured lipids via lipase-catalyzed incorporation of eicosapentaenoic acid into borage (Borago officinalis L.) and evening primrose (Oenothera biennis L.) oils. 2002 J. Agric. Food Chem. pmid:11804516
Jack AM et al. Effects of diabetes and evening primrose oil treatment on responses of aorta, corpus cavernosum and mesenteric vasculature in rats. 2002 Life Sci. pmid:12175702
Harris NM et al. Intravesical meglumine gamma-linolenic acid in superficial bladder cancer: an efficacy study. 2002 Eur. Urol. pmid:12121728
Hornych A et al. The effect of gamma-linolenic acid on plasma and membrane lipids and renal prostaglandin synthesis in older subjects. 2002 Bratisl Lek Listy pmid:12190041
Theander E et al. Gammalinolenic acid treatment of fatigue associated with primary Sjögren's syndrome. 2002 Scand. J. Rheumatol. pmid:12109650
Furse RK et al. Oral administration of gammalinolenic acid, an unsaturated fatty acid with anti-inflammatory properties, modulates interleukin-1beta production by human monocytes. 2002 J. Clin. Immunol. pmid:11998897
Gema H et al. Production of gamma-linolenic acid by Cunninghamella echinulata cultivated on glucose and orange peel. 2002 Appl. Microbiol. Biotechnol. pmid:11935180
Hong H et al. High-level production of gamma-linolenic acid in Brassica juncea using a delta6 desaturase from Pythium irregulare. 2002 Plant Physiol. pmid:12011365
Patel GK and Logan RA Golden nail pigmentation. 2002 J Dermatolog Treat pmid:12006139
Leigh-Firbank EC et al. Eicosapentaenoic acid and docosahexaenoic acid from fish oils: differential associations with lipid responses. 2002 Br. J. Nutr. pmid:12010583
Braddock R et al. gamma-Linoleic acid and ascorbic acid ameliorate the effects of experimental diabetes on electrolyte and bone homeostasis in pregnant rats. 2002 J. Endocrinol. pmid:12010635
Crook TJ et al. The effects of meglumine gamma linolenic acid (MeGLA) on an organ culture model of superficial bladder cancer. 2002 Urol. Res. pmid:11942327
García-Maroto F et al. Cloning and molecular characterization of the delta6-desaturase from two echium plant species: production of GLA by heterologous expression in yeast and tobacco. 2002 Lipids pmid:12030323
Colquhoun A Gamma-linolenic acid alters the composition of mitochondrial membrane subfractions, decreases outer mitochondrial membrane binding of hexokinase and alters carnitine palmitoyltransferase I properties in the Walker 256 rat tumour. 2002 Biochim. Biophys. Acta pmid:12069851
Menéndez JA et al. Synergistic interaction between vinorelbine and gamma-linolenic acid in breast cancer cells. 2002 Breast Cancer Res. Treat. pmid:12058962
Cook D et al. Modification of fatty acid composition in tomato (Lycopersicon esculentum) by expression of a borage delta6-desaturase. 2002 Mol. Biotechnol. pmid:12059112
Leaver HA et al. Antitumour and pro-apoptotic actions of highly unsaturated fatty acids in glioma. 2002 Prostaglandins Leukot. Essent. Fatty Acids pmid:12051954
Chung S et al. Gamma-linolenic acid in borage oil reverses epidermal hyperproliferation in guinea pigs. 2002 J. Nutr. pmid:12368400
Gillis RC et al. Eicosapentaenoic acid and gamma-linolenic acid induce apoptosis in HL-60 cells. 2002 J. Surg. Res. pmid:12384078
Pérez Y et al. Measurement by nuclear magnetic resonance diffusion of the dimensions of the mobile lipid compartment in C6 cells. 2002 Cancer Res. pmid:12384523
Ernst E Ayurvedic medicines. 2002 Pharmacoepidemiol Drug Saf pmid:12426929
Uesaka Y [Prevention and treatment of diabetic neuropathy]. 2002 Nippon Rinsho pmid:12430238
Hamburger M et al. Constituents in evening primrose oil with radical scavenging, cyclooxygenase, and neutrophil elastase inhibitory activities. 2002 J. Agric. Food Chem. pmid:12236675
Khunyoshyeng S et al. Differential expression of desaturases and changes in fatty acid composition during sporangiospore germination and development in Mucor rouxii. 2002 Fungal Genet. Biol. pmid:12223185
Whelan J et al. Dietary EPA reduces tumor load in ApcMin/+ mice by altering arachidonic acid metabolism, but conjugated linoleic acid, gamma--and alpha-linolenic acids have no effect. 2002 Adv. Exp. Med. Biol. pmid:12664643
Pham H and Ziboh VA 5 alpha-reductase-catalyzed conversion of testosterone to dihydrotestosterone is increased in prostatic adenocarcinoma cells: suppression by 15-lipoxygenase metabolites of gamma-linolenic and eicosapentaenoic acids. 2002 J. Steroid Biochem. Mol. Biol. pmid:12589947
Das UN Abrupt and complete occlusion of tumor-feeding vessels by gamma-linolenic acid. 2002 Nutrition pmid:12297217
Samuels R et al. Hypocholesterolemic effect of spirulina in patients with hyperlipidemic nephrotic syndrome. 2002 J Med Food pmid:12487756
Keegan A et al. Corpus cavernosum dysfunction in diabetic rats: effects of combined alpha-lipoic acid and gamma-linolenic acid treatment. 2001 Sep-Oct Diabetes Metab. Res. Rev. pmid:11747143
OtleÅŸ S and Pire R Fatty acid composition of Chlorella and Spirulina microalgae species. 2001 Nov-Dec J AOAC Int pmid:11767135
Zavodnik LB et al. [Effect of gamma-linolenic acid on microsomal oxidation in the rat liver following gamma-irradiation]. 2001 Jul-Aug Eksp Klin Farmakol pmid:11589114
Borenshtein D et al. Cataract development in diabetic sand rats treated with alpha-lipoic acid and its gamma-linolenic acid conjugate. 2001 Jan-Feb Diabetes Metab. Res. Rev. pmid:11241890
Nwankwo JO and Robbins ME Peroxisome proliferator-activated receptor- gamma expression in human malignant and normal brain, breast and prostate-derived cells. 2001 Apr-May Prostaglandins Leukot. Essent. Fatty Acids pmid:11418018
Cunnane SC et al. NMR and isotope ratio mass spectrometry studies of in vivo uptake and metabolism of polyunsaturates by the developing rat brain. 2001 Apr-Jun J. Mol. Neurosci. pmid:11478372
Kamphuis MM et al. Fat-specific satiety in humans for fat high in linoleic acid vs fat high in oleic acid. 2001 Eur J Clin Nutr pmid:11423927
Olguín EJ et al. The effect of low light flux and nitrogen deficiency on the chemical composition of Spirulina sp. (Arthrospira) grown on digested pig waste. 2001 Bioresour. Technol. pmid:11211071
Goffman FD and Galletti S Gamma-linolenic acid and tocopherol contents in the seed oil of 47 accessions from several Ribes species. 2001 J. Agric. Food Chem. pmid:11170598
Conti E et al. gamma-Linolenic acid production by solid-state fermentation of Mucorales strains on cereals. 2001 Bioresour. Technol. pmid:11198184
Tsimaratos M et al. Gamma-linolenic acid restores renal medullary thick ascending limb Na(+),K(+)-ATPase activity in diabetic rats. 2001 J. Nutr. pmid:11739860
Thies F et al. Influence of dietary supplementation with long-chain n-3 or n-6 polyunsaturated fatty acids on blood inflammatory cell populations and functions and on plasma soluble adhesion molecules in healthy adults. 2001 Lipids pmid:11795850
Kaku S et al. Interactions of dietary fats and proteins on fatty acid composition of immune cells and LTB4 production by peritoneal exudate cells of rats. 2001 Biosci. Biotechnol. Biochem. pmid:11302164