| MeSH term | MeSH ID | Detail |
|---|---|---|
| Stomach Ulcer | D013276 | 75 associated lipids |
| Kidney Failure, Chronic | D007676 | 51 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Neovascularization, Pathologic | D009389 | 39 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Lupus Erythematosus, Systemic | D008180 | 43 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
gamma-Linolenic acid
Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.
Cross Reference
Introduction
To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid
PubChem Associated disorders and diseases
What pathways are associated with gamma-Linolenic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with gamma-Linolenic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with gamma-Linolenic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
What genes are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
What common seen animal models are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with gamma-Linolenic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Ziboh VA and Fletcher MP | Dose-response effects of dietary gamma-linolenic acid-enriched oils on human polymorphonuclear-neutrophil biosynthesis of leukotriene B4. | 1992 | Am. J. Clin. Nutr. | pmid:1309474 |
| Mimouni V et al. | Evidence for insulin dependent hepatic microsomal gamma-linolenic acid chain elongation in spontaneously diabetic Wistar BB rats. | 1992 | Biochim. Biophys. Acta | pmid:1310052 |
| St Louis C et al. | Antihypertensive effect of gamma-linolenic acid in spontaneously hypertensive rats. | 1992 | Hypertension | pmid:1310479 |
| Lockett MJ and Tomlinson DR | The effects of dietary treatment with essential fatty acids on sciatic nerve conduction and activity of the Na+/K+ pump in streptozotocin-diabetic rats. | 1992 | Br. J. Pharmacol. | pmid:1313726 |
| Van Biervliet JP et al. | Serum cholesterol, cholesteryl ester, and high-density lipoprotein development in newborn infants: response to formulas supplemented with cholesterol and gamma-linolenic acid. | 1992 | J. Pediatr. | pmid:1313864 |
| de Kock M et al. | Effects of gamma-linolenic acid on mitosis and nuclear morphology in osteogenic sarcoma cells. | 1992 | S. Afr. Med. J. | pmid:1315459 |
| Bégin ME and Ells G | Levels of thiobarbituric acid reactive substances and the cytocidal potential of gammalinolenic and docosahexaenoic acids on ZR-75-1 and CV-1 cells. | 1992 | Lipids | pmid:1315901 |
| Duffy O et al. | Effects of an oil enriched in gamma linolenic acid on locomotor activity and behaviour in the Morris Maze, following in utero ethanol exposure in rats. | 1992 | Drug Alcohol Depend | pmid:1317288 |
| Kerscher MJ and Korting HC | Treatment of atopic eczema with evening primrose oil: rationale and clinical results. | 1992 | Clin Investig | pmid:1318129 |
| Gibson RA et al. | Gamma linolenic acid (GLA) content of encapsulated evening primrose oil products. | 1992 | Lipids | pmid:1318991 |
| Vaddadi KS | Use of gamma-linolenic acid in the treatment of schizophrenia and tardive dyskinesia. | 1992 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:1321448 |
| Horrobin DF | The relationship between schizophrenia and essential fatty acid and eicosanoid metabolism. | 1992 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:1321449 |
| Horrobin DF | The use of gamma-linolenic acid in diabetic neuropathy. | 1992 | Agents Actions Suppl. | pmid:1321553 |
| Ross MA et al. | Heparin reduces Fe(II)-catalyzed peroxidation of linolenic acid. | 1992 | Biochem. Soc. Trans. | pmid:1321761 |
| Fan YY and Chapkin RS | Mouse peritoneal macrophage prostaglandin E1 synthesis is altered by dietary gamma-linolenic acid. | 1992 | J. Nutr. | pmid:1322453 |
| Raederstorff D and Moser U | Borage or primrose oil added to standardized diets are equivalent sources for gamma-linolenic acid in rats. | 1992 | Lipids | pmid:1336802 |
| Mengeaud V et al. | Effects of eicosapentaenoic acid, gamma-linolenic acid and prostaglandin E1 on three human colon carcinoma cell lines. | 1992 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:1337209 |
| Girault C et al. | Effect of dietary gamma-linolenic acid on specific activities of delta 6 desaturation in obese Zucker rats. | 1992 | C. R. Seances Soc. Biol. Fil. | pmid:1337306 |
| Arundel BL | Evening primrose oil and epilepsy. | 1992 | Vet. Rec. | pmid:1475904 |
| Muriana FJ et al. | Fatty acid composition and properties of the liver microsomal membrane of rats fed diets enriched with cholesterol. | 1992 | J. Biochem. | pmid:1491012 |
| Cyclical breast pain--what works and what doesn't. | 1992 | Drug Ther Bull | pmid:1425218 | |
| Huang YS et al. | Effects of repeated gestation and lactation on milk n-6 fatty acid composition in rats fed on a diet rich in 18:2n-6 or 18:3n-6. | 1992 | Br. J. Nutr. | pmid:1445816 |
| Bond R and Lloyd DH | A double-blind comparison of olive oil and a combination of evening primrose oil and fish oil in the management of canine atopy. | 1992 | Vet. Rec. | pmid:1481346 |
| Howie A et al. | The influence of dietary essential fatty acids on uterine C20 and C22 fatty acid composition. | 1992 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:1502249 |
| Navarette R et al. | Dietary intake of concentrated gamma-linolenic acid (GLA)-enriched oil suppresses cutaneous level of dihomo-gamma-linolenic acid (DGLA): possible in vivo inhibition of microsomal elongation of GLA to DGLA. | 1992 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:1323857 |
| Scott DW et al. | Comparison of the clinical efficacy of two commercial fatty acid supplements (EfaVet and DVM Derm Caps), evening primrose oil, and cold water marine fish oil in the management of allergic pruritus in dogs: a double-blinded study. | 1992 | Cornell Vet | pmid:1643883 |
| Gateley CA et al. | Drug treatments for mastalgia: 17 years experience in the Cardiff Mastalgia Clinic. | 1992 | J R Soc Med | pmid:1548647 |
| Gateley CA et al. | Plasma fatty acid profiles in benign breast disorders. | 1992 | Br J Surg | pmid:1596720 |
| Nassar BA et al. | The effect of chemical hepatocarcinogenesis on liver phospholipid composition in rats fed N-6 and N-3 fatty acid-supplemented diets. | 1992 | Proc. Soc. Exp. Biol. Med. | pmid:1539039 |
| Jenkins AP et al. | Effects of bolus doses of fat on small intestinal structure and on release of gastrin, cholecystokinin, peptide tyrosine-tyrosine, and enteroglucagon. | 1992 | Gut | pmid:1541417 |
| Jenkins AP and Thompson RP | Effect of dietary fat on the distribution of mucosal mass and cell proliferation along the small intestine. | 1992 | Gut | pmid:1541418 |
| Ergan F et al. | Lipase specificity against some fatty acids? | 1992 | Ann. N. Y. Acad. Sci. | pmid:1335712 |
| Oon BB et al. | A diet enriched in essential fatty acids protects against the loss of lymphocytes which occurs in rats suffering from streptozotocin-induced diabetes. | 1992 | Exp. Physiol. | pmid:1543584 |
| Furuse M et al. | Effect of gamma-linolenic acid on lipid metabolism in laying hens. | 1992 | Comp Biochem Physiol A Comp Physiol | pmid:1347726 |
| Ormerod LD et al. | Eicosanoid modulation and epithelial wound healing kinetics of the alkali-burned cornea. | 1992 | J Ocul Pharmacol | pmid:1328428 |
| Barre DE and Holub BJ | The effect of borage oil consumption on the composition of individual phospholipids in human platelets. | 1992 | Lipids | pmid:1328794 |
| Fragoso YD and Skinner ER | The effect of gammalinolenic acid on the subfractions of plasma high density lipoprotein of the rabbit. | 1992 | Biochem. Pharmacol. | pmid:1329758 |
| Duffy O et al. | Attenuation of the effects of chronic ethanol administration in the brain lipid content of the developing rat by an oil enriched in gamma linolenic acid. | 1992 | Drug Alcohol Depend | pmid:1330473 |
| Hamberg M | Metabolism of 6,9,12-octadecatrienoic acid in the red alga Lithothamnion corallioides: mechanism of formation of a conjugated tetraene fatty acid. | 1992 | Biochem. Biophys. Res. Commun. | pmid:1332713 |
| Gunstone FD | Gamma linolenic acid--occurrence and physical and chemical properties. | 1992 | Prog. Lipid Res. | pmid:1334265 |
| Horrobin DF | Nutritional and medical importance of gamma-linolenic acid. | 1992 | Prog. Lipid Res. | pmid:1334266 |
| Engler MM et al. | Dietary gamma-linolenic acid lowers blood pressure and alters aortic reactivity and cholesterol metabolism in hypertension. | 1992 | J. Hypertens. | pmid:1335001 |
| McFayden IJ et al. | Cyclical breast pain--some observations and the difficulties in treatment. | 1992 | Br J Clin Pract | pmid:1286012 |
| Hayashi Y et al. | Anticancer effects of free polyunsaturated fatty acids in an oily lymphographic agent following intrahepatic arterial administration to a rabbit bearing VX-2 tumor. | 1992 | Cancer Res. | pmid:1309442 |
| Say B | A panacea for all ills? | 1991 Apr 10-16 | Nurs Times | pmid:2020583 |
| Ring J and Kleinheinz A | [Evening primrose oil in neurodermatitis?]. | 1991 | Med Monatsschr Pharm | pmid:1943974 |
| Horrobin DF et al. | The effects of evening primrose oil, safflower oil and paraffin on plasma fatty acid levels in humans: choice of an appropriate placebo for clinical studies on primrose oil. | 1991 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:1871175 |
| Arisaka M et al. | Fatty acid and prostaglandin metabolism in children with diabetes mellitus. II. The effect of evening primrose oil supplementation on serum fatty acid and plasma prostaglandin levels. | 1991 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:1871184 |
| Gateley CA and Mansel RE | Management of the painful and nodular breast. | 1991 | Br. Med. Bull. | pmid:1834299 |
| Hrelia S et al. | Kinetic analysis of delta-6-desaturation in liver microsomes: influence of gamma-linoleic acid dietary supplementation to young and old rats. | 1991 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:1808628 |
| Tauson AH et al. | Effect of evening primrose oil as food supplement on reproduction in the mink. | 1991 | Acta Vet. Scand. | pmid:1814183 |
| Tauson AH and Forsberg M | Effect of evening primrose oil as food supplement on reproduction in the blue fox. | 1991 | Acta Vet. Scand. | pmid:1814184 |
| Gardiner NS and Duncan JR | Possible involvement of delta-6-desaturase in control of melanoma growth by gamma-linolenic acid. | 1991 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:1650000 |
| Chapkin RS and Coble KJ | Utilization of gammalinolenic acid by mouse peritoneal macrophages. | 1991 | Biochim. Biophys. Acta | pmid:1655039 |
| Freeman MS et al. | The effects of essential fatty acid supplementation on lithium absorption kinetics in guinea pig jejunum. | 1991 | Biochem. Soc. Trans. | pmid:1665438 |
| Melnik B and Plewig G | Atopic dermatitis and disturbances of essential fatty acid and prostaglandin E metabolism. | 1991 | J. Am. Acad. Dermatol. | pmid:1666398 |
| Gilani S et al. | Chick embryonic development following exposure to ethanol, gamma-linolenic and linolenic acids. | 1991 | Anat Anz | pmid:1666823 |
| KristofÃková L et al. | Selection of Rhizopus strains for L(+)-lactic acid and gamma-linolenic acid production. | 1991 | Folia Microbiol. (Praha) | pmid:1668279 |
| Simpson LO | Melanoma and fatty acids. | 1991 | N. Z. Med. J. | pmid:1996191 |
| Brzeski M et al. | Evening primrose oil in patients with rheumatoid arthritis and side-effects of non-steroidal anti-inflammatory drugs. | 1991 | Br. J. Rheumatol. | pmid:1913008 |
| Recently introduced products. | 1991 | Drug Ther Bull | pmid:1935601 | |
| Holborow P | Melanoma and polyunsaturated fat. | 1991 | N. Z. Med. J. | pmid:2006066 |
| Holborow P | Melanoma and fatty acids. | 1991 | N. Z. Med. J. | pmid:2008253 |
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| Cameron NE et al. | Essential fatty acid diet supplementation. Effects on peripheral nerve and skeletal muscle function and capillarization in streptozocin-induced diabetic rats. | 1991 | Diabetes | pmid:2022301 |
| Izumi T et al. | Purification of two forms of arachidonate 15-lipoxygenase from human leukocytes. | 1991 | Eur. J. Biochem. | pmid:1662607 |
| Wright S | Atopic eczema. | 1991 | J R Coll Physicians Lond | pmid:1920221 |
| Schäfer L and Kragballe K | Supplementation with evening primrose oil in atopic dermatitis: effect on fatty acids in neutrophils and epidermis. | 1991 | Lipids | pmid:1943500 |
| Das UN | Tumoricidal action of cis-unsaturated fatty acids and their relationship to free radicals and lipid peroxidation. | 1991 | Cancer Lett. | pmid:1850658 |
| Ulmann L et al. | Incorporation into liver microsomal lipids of linoleic and stearic acids and of their respective products of delta 6 and delta 9 desaturation, gamma-linolenic and oleic acids: effect of age and of blackcurrant seed oil. | 1991 | Biochim. Biophys. Acta | pmid:1657182 |
| Julu PO and Mutamba A | Comparison of short-term effects of insulin and essential fatty acids on the slowed nerve conduction of streptozotocin diabetes in rats. | 1991 | J. Neurol. Sci. | pmid:1663993 |
| Biagi PL et al. | Gamma-linolenic acid dietary supplementation can reverse the aging influence on rat liver microsome delta 6-desaturase activity. | 1991 | Biochim. Biophys. Acta | pmid:1674661 |
| Sircar S et al. | Transformation renders MDR cells more sensitive to polyunsaturated fatty acids. | 1990 Nov-Dec | Anticancer Res. | pmid:2178327 |
| Ikushima S et al. | Gamma linolenic acid alters the cytotoxic activity of anticancer drugs on cultured human neuroblastoma cells. | 1990 Jul-Aug | Anticancer Res. | pmid:2166461 |
| Schrek R | An animal model for intractable chronic lymphocytic leukemia. | 1990 | Med. Hypotheses | pmid:1963468 |
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| Sharpe GR and Farr PM | Evening primrose oil and eczema. | 1990 | Lancet | pmid:1969047 |
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| Chapkin RS and Carmichael SL | Effect of dietary blackcurrant seed oil on mouse macrophage subclasses of choline and ethanolamine glycerophospholipids. | 1990 | J. Nutr. | pmid:1974284 |
| Dodge JA et al. | Paradoxical effects of essential fatty acid supplementation on lipid profiles and sweat electrolytes in cystic fibrosis. | 1990 | Br. J. Nutr. | pmid:2185826 |
| Mansel RE et al. | A randomized trial of dietary intervention with essential fatty acids in patients with categorized cysts. | 1990 | Ann. N. Y. Acad. Sci. | pmid:2192634 |
| Nakahara T et al. | Inhibitory effects of mold oil including gamma-linolenate on platelet thrombus formation in mesenteric microvessels of the rat. | 1990 | Thromb. Res. | pmid:2156348 |
| Roemen TH et al. | Quantitative assessment of gamma-linolenic acid in human blood and plasma with capillary gas chromatography. | 1990 | J. Chromatogr. | pmid:2166745 |
| Cleland LG et al. | The effect of dietary fish oil supplement upon the content of dihomo-gammalinolenic acid in human plasma phospholipids. | 1990 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:2169063 |
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| Hirschberg Y et al. | The response to endotoxin in guinea pigs after intravenous black currant seed oil. | 1990 | Lipids | pmid:2170795 |
| Simpson LO | Melanoma and fatty acids. | 1990 | N. Z. Med. J. | pmid:2173823 |
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| Watson J et al. | Mechanism of action of polyunsaturated fatty acids in rheumatoid arthritis. | 1990 | Biochem. Soc. Trans. | pmid:2379720 |
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| Sangeetha P et al. | Free radical generation in human leukocytes by CIS-unsaturated fatty acids is a calmodulin dependent process. | 1990 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:2160083 |
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