gamma-Linolenic acid

Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.

Cross Reference

Introduction

To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid

MeSH term MeSH ID Detail
Stomach Ulcer D013276 75 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Adenocarcinoma D000230 166 associated lipids
Pain D010146 64 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Lung Neoplasms D008175 171 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Inflammation D007249 119 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with gamma-Linolenic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with gamma-Linolenic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with gamma-Linolenic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with gamma-Linolenic acid

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Authors Title Published Journal PubMed Link
Fuller MA et al. Activity of soybean lipoxygenase isoforms against esterified fatty acids indicates functional specificity. 2001 Arch. Biochem. Biophys. pmid:11361131
Kamphuis MM et al. Fat-specific satiety in humans for fat high in linoleic acid vs fat high in oleic acid. 2001 Eur J Clin Nutr pmid:11423927
Chakrabarti KB et al. Modification of doxorubicin-induced cardiotoxicity: effect of essential fatty acids and ICRF-187 (dexrazoxane). 2001 Eur. J. Cancer pmid:11435077
Banni S et al. Vaccenic acid feeding increases tissue levels of conjugated linoleic acid and suppresses development of premalignant lesions in rat mammary gland. 2001 Nutr Cancer pmid:12094634
Olguín EJ et al. The effect of low light flux and nitrogen deficiency on the chemical composition of Spirulina sp. (Arthrospira) grown on digested pig waste. 2001 Bioresour. Technol. pmid:11211071
Hounsom L et al. Oxidative stress participates in the breakdown of neuronal phenotype in experimental diabetic neuropathy. 2001 Diabetologia pmid:11357471
Goffman FD and Galletti S Gamma-linolenic acid and tocopherol contents in the seed oil of 47 accessions from several Ribes species. 2001 J. Agric. Food Chem. pmid:11170598
Conti E et al. gamma-Linolenic acid production by solid-state fermentation of Mucorales strains on cereals. 2001 Bioresour. Technol. pmid:11198184
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Corbett JW et al. Trifluoromethyl-containing 3-alkoxymethyl- and 3-aryloxymethyl-2-pyridinones are potent inhibitors of HIV-1 non-nucleoside reverse transcriptase. 2001 Bioorg. Med. Chem. Lett. pmid:11212098
Agostoni C et al. Biochemical effects of supplemented long-chain polyunsaturated fatty acids in hyperphenylalaninemia. 2001 Prostaglandins Leukot. Essent. Fatty Acids pmid:11237478
Ito Y et al. Effects of polyunsaturated fatty acids on atrophic gastritis in a Japanese population. 2001 Cancer Lett. pmid:11165751
Reinikainen M et al. The toxicities of a polyunsaturated fatty acid and a microcystin to Daphnia magna. 2001 Environ. Toxicol. pmid:11594032
Agatha G et al. Fatty acid composition of lymphocyte membrane phospholipids in children with acute leukemia. 2001 Cancer Lett. pmid:11597788
Wollheim FA [Meager support for herbal therapy of rheumatoid arthritis]. 2001 Lakartidningen pmid:11699249
Kast RE Borage oil reduction of rheumatoid arthritis activity may be mediated by increased cAMP that suppresses tumor necrosis factor-alpha. 2001 Int. Immunopharmacol. pmid:11710548
Ide T et al. Dietary mold oil rich in gamma linolenic acid increases insulin-dependent glucose utilization in isolated rat adipocytes. 2001 Comp. Biochem. Physiol. B, Biochem. Mol. Biol. pmid:11567903
Kaku S et al. Dietary gamma-linolenic acid dose-dependently modifies fatty acid composition and immune parameters in rats. 2001 Prostaglandins Leukot. Essent. Fatty Acids pmid:11728173
Colquhoun A and Schumacher RI gamma-Linolenic acid and eicosapentaenoic acid induce modifications in mitochondrial metabolism, reactive oxygen species generation, lipid peroxidation and apoptosis in Walker 256 rat carcinosarcoma cells. 2001 Biochim. Biophys. Acta pmid:11731331
Birch AE et al. Antioxidant properties of evening primrose seed extracts. 2001 J. Agric. Food Chem. pmid:11559161
Demmelmair H et al. Influence of formulas with borage oil or borage oil plus fish oil on the arachidonic acid status in premature infants. 2001 Lipids pmid:11485158
Guil-Guerrero JL et al. Occurrence and characterization of oils rich in gamma-linolenic acid (III): the taxonomical value of the fatty acids in Echium (Boraginaceae). 2001 Phytochemistry pmid:11524120
Ford I et al. The effects of treatment with alpha-lipoic acid or evening primrose oil on vascular hemostatic and lipid risk factors, blood flow, and peripheral nerve conduction in the streptozotocin-diabetic rat. 2001 Metab. Clin. Exp. pmid:11474472
Tsimaratos M et al. Gamma-linolenic acid restores renal medullary thick ascending limb Na(+),K(+)-ATPase activity in diabetic rats. 2001 J. Nutr. pmid:11739860
Thies F et al. Influence of dietary supplementation with long-chain n-3 or n-6 polyunsaturated fatty acids on blood inflammatory cell populations and functions and on plasma soluble adhesion molecules in healthy adults. 2001 Lipids pmid:11795850
Kaku S et al. Interactions of dietary fats and proteins on fatty acid composition of immune cells and LTB4 production by peritoneal exudate cells of rats. 2001 Biosci. Biotechnol. Biochem. pmid:11302164
Sims EC and Plowman PN Stereotactic radiosurgery XII. Large AVM and the failure of the radiation response modifier gamma linolenic acid to improve the therapeutic ratio. 2001 Br J Neurosurg pmid:11303657
Little C and Parsons T Herbal therapy for treating rheumatoid arthritis. 2001 Cochrane Database Syst Rev pmid:11279784
Fauconnot L and Buist PH Gamma-linolenic acid biosynthesis: cryptoregiochemistry of delta6 desaturation. 2001 J. Org. Chem. pmid:11312950
Kenny FS et al. Effect of dietary GLA+/-tamoxifen on the growth, ER expression and fatty acid profile of ER positive human breast cancer xenografts. 2001 Int. J. Cancer pmid:11291069
Colquhoun A and Schumacher RI Modifications in mitochondrial metabolism and ultrastructure and their relationship to tumour growth inhibition by gamma-linolenic acid. 2001 Mol. Cell. Biochem. pmid:11330827
Serrano I et al. Ethanol-induced dimorphism and lipid composition changes in Mucor fragilis CCMI 142. 2001 Lett. Appl. Microbiol. pmid:11442823
Hou X et al. 2,3-Dinor-5,6-dihydro-15-F(2t)-isoprostane: a bioactive prostanoid metabolite. 2001 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:11448840
Fan YY et al. Dietary gamma-linolenic acid suppresses aortic smooth muscle cell proliferation and modifies atherosclerotic lesions in apolipoprotein E knockout mice. 2001 J. Nutr. pmid:11385052
Nwankwo JO Repression of cellular anaplerosis as the hypothesized mechanism of gamma-linolenic acid-induced toxicity to tumor cells. 2001 Med. Hypotheses pmid:11388772
Furse RK et al. Gammalinolenic acid, an unsaturated fatty acid with anti-inflammatory properties, blocks amplification of IL-1 beta production by human monocytes. 2001 J. Immunol. pmid:11418687
Thies F et al. Dietary supplementation with gamma-linolenic acid or fish oil decreases T lymphocyte proliferation in healthy older humans. 2001 J. Nutr. pmid:11435508
Yogo Y and Fujishima S [Nutritional support for ARDS]. 2001 Nippon Rinsho pmid:11439576
Frenoux JM et al. A polyunsaturated fatty acid diet lowers blood pressure and improves antioxidant status in spontaneously hypertensive rats. 2001 J. Nutr. pmid:11208936
Berry JA Benign breast pain. New approaches manage this common condition more effectively. 2001 Adv Nurse Pract pmid:12400335
Chan LW et al. Microencapsulation of oils using sodium alginate. 2000 Nov-Dec J Microencapsul pmid:11063422
Iijima S et al. Oral supplementation with gamma-linolenic acid extracted from Mucor circinelloides improves the deformability of red blood cells in hemodialysis patients. 2000 Nephron pmid:11014980
Arnold LE et al. Does zinc moderate essential fatty acid and amphetamine treatment of attention-deficit/hyperactivity disorder? 2000 J Child Adolesc Psychopharmacol pmid:10933121
Guil-Guerrero JL et al. Occurrence and characterization of oils rich in gamma-linolenic acid part II: fatty acids and squalene from Macaronesian Echium leaves. 2000 Phytochemistry pmid:10939357
Liu QY and Tan BK Effects of cis-unsaturated fatty acids on doxorubicin sensitivity in P388/DOX resistant and P388 parental cell lines. 2000 Life Sci. pmid:10954054
Parker-Barnes JM et al. Identification and characterization of an enzyme involved in the elongation of n-6 and n-3 polyunsaturated fatty acids. 2000 Proc. Natl. Acad. Sci. U.S.A. pmid:10899997
Rahbeeni F et al. The effect of evening primrose oil on the radiation response and blood flow of mouse normal and tumour tissue. 2000 Int. J. Radiat. Biol. pmid:10902742
Kapoor R and Klimaszewski A Efficacy of borage oil in patients with atopic eczema. 2000 Br. J. Dermatol. pmid:10886164
Takahashi Y et al. Dietary gamma-linolenic acid in the form of borage oil causes less body fat accumulation accompanying an increase in uncoupling protein 1 mRNA level in brown adipose tissue. 2000 Comp. Biochem. Physiol. B, Biochem. Mol. Biol. pmid:11079375