| MeSH term | MeSH ID | Detail |
|---|---|---|
| Stomach Ulcer | D013276 | 75 associated lipids |
| Kidney Failure, Chronic | D007676 | 51 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Neovascularization, Pathologic | D009389 | 39 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Lupus Erythematosus, Systemic | D008180 | 43 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
gamma-Linolenic acid
Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.
Cross Reference
Introduction
To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid
PubChem Associated disorders and diseases
What pathways are associated with gamma-Linolenic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with gamma-Linolenic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with gamma-Linolenic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
What genes are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
What common seen animal models are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with gamma-Linolenic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Furuse M et al. | Effect of gamma-linolenic acid on lipid metabolism in laying hens. | 1992 | Comp Biochem Physiol A Comp Physiol | pmid:1347726 |
| Tocher DR et al. | Effect of diets enriched in Delta6 desaturated fatty acids (18:3n-6 and 18:4n-3), on growth, fatty acid composition and highly unsaturated fatty acid synthesis in two populations of Arctic charr (Salvelinus alpinus L.). | 2006 | Comp. Biochem. Physiol. B, Biochem. Mol. Biol. | pmid:16630735 |
| Takahashi Y et al. | Dietary gamma-linolenic acid in the form of borage oil causes less body fat accumulation accompanying an increase in uncoupling protein 1 mRNA level in brown adipose tissue. | 2000 | Comp. Biochem. Physiol. B, Biochem. Mol. Biol. | pmid:11079375 |
| Ide T et al. | Dietary mold oil rich in gamma linolenic acid increases insulin-dependent glucose utilization in isolated rat adipocytes. | 2001 | Comp. Biochem. Physiol. B, Biochem. Mol. Biol. | pmid:11567903 |
| Ihara-Watanabe M et al. | Effects of dietary alpha- or gamma-linolenic acid on levels and fatty acid compositions of serum and hepatic lipids, and activity and mRNA abundance of 3-hydroxy-3-methylglutaryl CoA reductase in rats. | 1999 | Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. | pmid:10327618 |
| Darlington LG and Ramsey NW | Review of dietary therapy for rheumatoid arthritis. | 1994 | Compr Ther | pmid:7805365 |
| Budeiri D et al. | Is evening primrose oil of value in the treatment of premenstrual syndrome? | 1996 | Control Clin Trials | pmid:8721802 |
| Barabino S et al. | Systemic linoleic and gamma-linolenic acid therapy in dry eye syndrome with an inflammatory component. | 2003 | Cornea | pmid:12605039 |
| Pinna A et al. | Effect of oral linoleic and gamma-linolenic acid on meibomian gland dysfunction. | 2007 | Cornea | pmid:17413949 |
| Scott DW et al. | Comparison of the clinical efficacy of two commercial fatty acid supplements (EfaVet and DVM Derm Caps), evening primrose oil, and cold water marine fish oil in the management of allergic pruritus in dogs: a double-blinded study. | 1992 | Cornell Vet | pmid:1643883 |
| Pontes-Arruda A et al. | Enteral nutrition with eicosapentaenoic acid, γ-linolenic acid and antioxidants in the early treatment of sepsis: results from a multicenter, prospective, randomized, double-blinded, controlled study: the INTERSEPT study. | 2011 | Crit Care | pmid:21658240 |
| Das UN | n-3 fatty acids, γ-linolenic acid, and antioxidants in sepsis. | 2013 | Crit Care | pmid:23597172 |
| Schott CK and Huang DT | ω-3 fatty acids, γ-linolenic acid, and antioxidants: immunomodulators or inert dietary supplements? | 2012 | Crit Care | pmid:23176247 |
| Machado FR et al. | INTERSEPT study: we still need more clarity. | 2012 | Crit Care | pmid:22410246 |
| Machado FR | Fish oil and sepsis: we still need more trials. | 2011 | Crit Care | pmid:22112369 |
| Mancuso P et al. | Dietary fish oil and fish and borage oil suppress intrapulmonary proinflammatory eicosanoid biosynthesis and attenuate pulmonary neutrophil accumulation in endotoxic rats. | 1997 | Crit. Care Med. | pmid:9233748 |
| Mancuso P et al. | Effects of eicosapentaenoic and gamma-linolenic acid on lung permeability and alveolar macrophage eicosanoid synthesis in endotoxic rats. | 1997 | Crit. Care Med. | pmid:9118672 |
| Pontes-Arruda A et al. | Effects of enteral feeding with eicosapentaenoic acid, gamma-linolenic acid, and antioxidants in mechanically ventilated patients with severe sepsis and septic shock. | 2006 | Crit. Care Med. | pmid:16850002 |
| Singer P et al. | Benefit of an enteral diet enriched with eicosapentaenoic acid and gamma-linolenic acid in ventilated patients with acute lung injury. | 2006 | Crit. Care Med. | pmid:16484911 |
| Pacht ER | Enteral therapy to decrease morbidity and improve survival in acute respiratory distress syndrome: its time has come. | 2006 | Crit. Care Med. | pmid:16921322 |
| Gasperino J and Kvetan V | Acute lung injury and nutritional support. | 2006 | Crit. Care Med. | pmid:16550085 |
| Karlstad MD et al. | Effect of intravenous lipid emulsions enriched with gamma-linolenic acid on plasma n-6 fatty acids and prostaglandin biosynthesis after burn and endotoxin injury in rats. | 1993 | Crit. Care Med. | pmid:8222692 |
| Gadek JE et al. | Effect of enteral feeding with eicosapentaenoic acid, gamma-linolenic acid, and antioxidants in patients with acute respiratory distress syndrome. Enteral Nutrition in ARDS Study Group. | 1999 | Crit. Care Med. | pmid:10470743 |
| Palombo JD et al. | Effect of short-term enteral feeding with eicosapentaenoic and gamma-linolenic acids on alveolar macrophage eicosanoid synthesis and bactericidal function in rats. | 1999 | Crit. Care Med. | pmid:10507617 |
| Wiedemann HP | Fish oil is not the fix for acute lung injury. | 2011 | Crit. Care Med. | pmid:21685749 |
| Curtis L | High-quality enteral nutrition essential for reducing morbidity and mortality in acute care patients. | 2007 | Crit. Care Med. | pmid:17421112 |
| Ortiz-Leyba C and Garnacho-Montero J | Saving lives in severe sepsis with the help of enteral nutrition. | 2007 | Crit. Care Med. | pmid:17421113 |
| Pacht ER et al. | Enteral nutrition with eicosapentaenoic acid, gamma-linolenic acid, and antioxidants reduces alveolar inflammatory mediators and protein influx in patients with acute respiratory distress syndrome. | 2003 | Crit. Care Med. | pmid:12576957 |
| Lindemann J et al. | Clinical study of the effects on asthma-related QOL and asthma management of a medical food in adult asthma patients. | 2009 | Curr Med Res Opin | pmid:19811112 |
| Surette ME et al. | The impact of a medical food containing gammalinolenic and eicosapentaenoic acids on asthma management and the quality of life of adult asthma patients. | 2008 | Curr Med Res Opin | pmid:18194593 |
| Das UN | Tumoricidal and anti-angiogenic actions of gamma-linolenic acid and its derivatives. | 2006 | Curr Pharm Biotechnol | pmid:17168663 |
| Morse NL and Clough PM | A meta-analysis of randomized, placebo-controlled clinical trials of Efamol evening primrose oil in atopic eczema. Where do we go from here in light of more recent discoveries? | 2006 | Curr Pharm Biotechnol | pmid:17168667 |
| Kapoor R and Huang YS | Gamma linolenic acid: an antiinflammatory omega-6 fatty acid. | 2006 | Curr Pharm Biotechnol | pmid:17168669 |
| Goldfien A | Premenstrual syndrome. | 1994 | Curr Ther Endocrinol Metab | pmid:7704719 |
| Mettang T | Uremic Itch Management. | 2016 | Curr. Probl. Dermatol. | pmid:27578082 |
| Mayo TT et al. | Comparative study on bruise reduction treatments after bruise induction using the pulsed dye laser. | 2013 | Dermatol Surg | pmid:23899131 |
| Whitaker DK et al. | Evening primrose oil (Epogam) in the treatment of chronic hand dermatitis: disappointing therapeutic results. | 1996 | Dermatology (Basel) | pmid:8884146 |
| Worm M and Henz BM | Novel unconventional therapeutic approaches to atopic eczema. | 2000 | Dermatology (Basel) | pmid:11096188 |
| Jamal GA | The use of gamma linolenic acid in the prevention and treatment of diabetic neuropathy. | 1994 | Diabet. Med. | pmid:8200197 |
| Jamal GA and Carmichael H | The effect of gamma-linolenic acid on human diabetic peripheral neuropathy: a double-blind placebo-controlled trial. | 1990 | Diabet. Med. | pmid:2159860 |
| Shotton HR et al. | The effectiveness of treatments of diabetic autonomic neuropathy is not the same in autonomic nerves supplying different organs. | 2003 | Diabetes | pmid:12502507 |
| Horrobin DF | Essential fatty acids in the management of impaired nerve function in diabetes. | 1997 | Diabetes | pmid:9285506 |
| Cameron NE et al. | Essential fatty acid diet supplementation. Effects on peripheral nerve and skeletal muscle function and capillarization in streptozocin-induced diabetic rats. | 1991 | Diabetes | pmid:2022301 |
| Keen H et al. | Treatment of diabetic neuropathy with gamma-linolenic acid. The gamma-Linolenic Acid Multicenter Trial Group. | 1993 | Diabetes Care | pmid:8380765 |
| Borenshtein D et al. | Cataract development in diabetic sand rats treated with alpha-lipoic acid and its gamma-linolenic acid conjugate. | 2001 Jan-Feb | Diabetes Metab. Res. Rev. | pmid:11241890 |
| Keegan A et al. | Corpus cavernosum dysfunction in diabetic rats: effects of combined alpha-lipoic acid and gamma-linolenic acid treatment. | 2001 Sep-Oct | Diabetes Metab. Res. Rev. | pmid:11747143 |
| Dines KC et al. | Contrasting effects of treatment with omega-3 and omega-6 essential fatty acids on peripheral nerve function and capillarization in streptozotocin-diabetic rats. | 1993 | Diabetologia | pmid:8270127 |
| Tomlinson DR et al. | Essential fatty acid treatment--effects on nerve conduction, polyol pathway and axonal transport in streptozotocin diabetic rats. | 1989 | Diabetologia | pmid:2477293 |
| Karasu C et al. | Effects of anti-oxidant treatment on sciatic nerve dysfunction in streptozotocin-diabetic rats; comparison with essential fatty acids. | 1995 | Diabetologia | pmid:7713308 |
| van Doormaal JJ et al. | Effects of short-term high dose intake of evening primrose oil on plasma and cellular fatty acid compositions, alpha-tocopherol levels, and erythropoiesis in normal and type 1 (insulin-dependent) diabetic men. | 1988 | Diabetologia | pmid:3065111 |